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Browse our CRHR1 Proteins (CRHR1)

Full name:
Corticotropin Releasing Hormone Receptor 1 Proteins (CRHR1)
On are 13 Corticotropin Releasing Hormone Receptor 1 (CRHR1) Proteins from 3 different suppliers available. Additionally we are shipping CRHR1 Antibodies (163) and CRHR1 Kits (19) and many more products for this protein. A total of 202 CRHR1 products are currently listed.
CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRH-R1h, Crhr, crhr1, crhr1-A, CRHR1f, CRHR1L
list all proteins Gene Name GeneID UniProt
CRHR1 1394 P34998
CRHR1 12921 P35347
Rat CRHR1 CRHR1 58959 P35353

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CRHR1 Proteins (CRHR1) by Origin

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Top referenced CRHR1 Proteins

  1. Human CRHR1 Protein expressed in Wheat germ - ABIN1350338 : Xu, Xu, Hennebold, Molskness, Stouffer: Expression and role of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate corpus luteum during the menstrual cycle. in Endocrinology 2007 (PubMed)

More Proteins for CRHR1 Interaction Partners

Pig (Porcine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. CRFr1 activation mediates intestinal mucosa barrier dysfunction and hypersecretion in early-weaned piglets, whereas CRFr2 (show CRHR2 Proteins) activation may be responsible for novel protective properties in the porcine intestine in response to early life stress.

Horse (Equine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. The expression of UCN, CRHR1, CRHR2 and CRHBP by immunohistochemistry, Western blot and reverse transcription with the polymerase chain reaction (RT-PCR) in the horse thyroid gland, was investigated

Human Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. cardiac expression of CRFR1, CRF (show CRH Proteins), and Ucn3 (show UCN3 Proteins) genes is elevated in heart failure and may contribute to the activation of the CRF (show CRH Proteins)/Ucn system in these patients. A common variant within the CRFR1 gene and a novel CRFR1 splice variant may modulate CRFR1 expression and signaling.

  2. there are brain region- and cell type-specific effects of CRFR signalling that are influenced by the individual's prior experience and that shape molecular, cellular and ultimately behavioural responses to stressful challenges.

  3. This study showed that associations between BPD and haplotype combinations of the genes FKBP5 (show FKBP5 Proteins) and CRHR1.

  4. replicated the initially reported association of the CRHR1 rs878886 G-allele with cued fear acquisition deficits, albeit with a different pattern of results regarding the interaction with 5-HTT (show SLC6A4 Proteins) variation

  5. hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-34a can regulate the CRH (show CRH Proteins)/CRHR1/POMC (show POMC Proteins) axis and may influence body mass index.

  6. results found that among children with no copies of the protective CRHR1 TAT (show TAT Proteins) haplotype, children of mothers with a history of Manic Depressive Disorder had significantly higher levels of brooding than children of mothers with no history of depression.

  7. The CRHR1 gene reduces the risk for depressive symptoms among youths living in families undergoing high levels of economic hardship.

  8. CAL (show FBLIM1 Proteins) can regulate the anterograde trafficking, the internalization as well as the signaling of CRFR1 via modulating the post-translational modifications that the receptor undergoes at the Golgi apparatus.

  9. CRF-R1 activation by CRF and UCN inhibits the proliferation of SK-N-SH (N) cells and promotes neuronal-like differentiation.

  10. The results revealed that changes in depressive symptoms over time depended on both intervention group and genotypes (5-HTTLPR (show SLC6A4 Proteins) and CRHR1).

Mouse (Murine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. Study demonstrated that CRF1 receptor-deficiency prolongs whereas CRF2 receptor (show CRHR2 Proteins)-deficiency shortens the duration of recognition memory deficits induced by morphine discontinuation, unraveling opposite roles for the two known CRF (show CRH Proteins) receptor subtypes in cognitive dysfunction associated with opiate withdrawal.

  2. CRFR1, in a subset of AgRP (show AGRP Proteins) neurons, plays a regulatory role that enables appropriate sympathetic nervous system activation and consequently protects the organism from hypothermia and hypoglycemia.

  3. the cyclic AMP (show TMPRSS5 Proteins) (cAMP) response of CRHR1 in physiologically relevant scenarios engages separate cAMP sources, involving the atypical soluble adenylyl cyclase (sAC (show ADCY10 Proteins)) in addition to transmembrane adenylyl cyclases (tmACs).

  4. Data suggest a physiologically relevant role for local corticotropin-releasing hormone (show CRH Proteins) signaling towards shaping the neuronal circuitry within the mouse olfactory bulb.

  5. A role was found for extra-hypothalamic CRF-R1 in stress-escalated alcohol drinking.

  6. This study demonstrated that an anatomical mechanism for sex-differences in the convergent modulation of ventrolateral medulla catecholaminergic neurons by CRF (show CRH Proteins) and glutamate (show GRIN1 Proteins).

  7. these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.

  8. bladder smooth muscle contractility is unchanged by CsA (show HSPA9 Proteins); however, there are changes in the levels of the downstream transcription factors MEF-2 (show MYEF2 Proteins) and NFAT (show NFATC1 Proteins).

  9. The genetic disruption of the CRF1R pathway decreased the period of extinction in males and females suggesting that CRF (show CRH Proteins)/CRF1R is implicated in the duration of aversive memory.

  10. Anatomical and biochemical findings demonstrate that accumulation of Abeta (show APP Proteins) is significantly reduced in the brain of Alzheimer's disease model mice lacking CRFR1 providing support for a direct relationship between CRFR1 and Abeta (show APP Proteins) production pathways

Cow (Bovine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN, CRHR1 and CRHR2 and that UCN plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.

  2. CRHR1 and CRHR2 (show CRHR2 Proteins) are expressed in the bovine adrenal gland.

  3. results indicate that arginine vasopressin (show AVP Proteins) receptor V3 and corticotropin-releasing factor receptor 1 mRNAs are coordinately downregulated in the anterior pituitary during systemic inflammatory stress in cattle[AVP receptor V3 (show AVPR1B Proteins)]

Rhesus Monkey Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. The results of this study suggested that variation in CRHR1 may influence brain function before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes and childhood trauma reported to affect human psychopathology

Xenopus laevis Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. CRF (show CRH Proteins) is expressed in tadpole tail, is up-regulated by environmental stressors, and is cytoprotective

CRHR1 Protein Profile

Protein Summary

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346.

Alternative names and synonyms associated with CRHR1

  • corticotropin releasing hormone receptor 1 (CRHR1)
  • corticotropin releasing hormone receptor 1 (Crhr1)
  • corticotropin releasing hormone receptor 1, gene 2 (crhr1.2)
  • CRF-R protein
  • CRF-R-1 protein
  • CRF-R1 protein
  • CRF1 protein
  • CRFR-1 protein
  • CRFR1 protein
  • CRH-R-1 protein
  • CRH-R1 protein
  • CRH-R1h protein
  • Crhr protein
  • crhr1 protein
  • crhr1-A protein
  • CRHR1f protein
  • CRHR1L protein

Protein level used designations for CRHR1

corticotropin releasing hormone receptor type I , corticotropin-releasing factor receptor 1 , corticotropin releasing hormone receptor 1 , corticotropin releasing hormone receptor variant 1e , corticotropin releasing hormone receptor variant 1g , corticotropin-releasing factor type 1 receptor , corticotropin-releasing hormone receptor 1 , seven transmembrane helix receptor , CRF 1 receptor , CRF-R-1 , CRF-R1 , CRF-R1alpha , CRFR-1 , CRH-R-1 , CRH-R1 , CRF-R , CRF1 , CRH-R 1 , corticotrophin releasing hormone receptor 1 , corticotropin releasing hormone 1 , corticotropin releasing factor receptor type 1 , corticotrophin-releasing factor type 1 alpha receptor

397426 Sus scrofa
468283 Pan troglodytes
723971 Felis catus
100065598 Equus caballus
1394 Homo sapiens
12921 Mus musculus
58959 Rattus norvegicus
610380 Canis lupus familiaris
281716 Bos taurus
443025 Ovis aries
100302436 Oryctolagus cuniculus
374218 Gallus gallus
574095 Macaca mulatta
373580 Xenopus laevis
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