CRHR1 Protein (AA 23-121) (His tag)
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- Target See all CRHR1 Proteins
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-121
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This CRHR1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSLQDQHCES LSPASNVSGL QCNASVDLIG TCWPRSPARQ LVVRPCPAFF YGVRYNTTNN GYRECLANGS WAARVNYSEC QEILNEEKKS KVHYHVAVI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CRHR1 Protein
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Corticotropin Releasing Hormone Receptor 1 (CRHR1) (AA 24-121) protein (GST tag)
CRHR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Corticotropin Releasing Hormone Receptor 1 (CRHR1) (AA 1-415) protein (GST tag)CRHR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Corticotropin Releasing Hormone Receptor 1 (CRHR1) (AA 24-444) protein (rho-1D4 tag)Crystallography grade CRHR1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Corticotropin Releasing Hormone Receptor 1 (CRHR1) (AA 24-415) protein (rho-1D4 tag)Crystallography grade CRHR1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Corticotropin Releasing Hormone Receptor 1 (CRHR1) (AA 24-121) protein (GST tag)CRHR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- Alternative Name
- CRFR1 (CRHR1 Products)
- Synonyms
- CRF-R Protein, CRF-R-1 Protein, CRF-R1 Protein, CRF1 Protein, CRFR-1 Protein, CRFR1 Protein, CRH-R-1 Protein, CRH-R1 Protein, CRH-R1h Protein, CRHR Protein, CRHR1L Protein, CRHR1f Protein, Crhr Protein, crhr1 Protein, crhr1-A Protein, CRHR1 Protein, CRHR1-IT1-CRHR1 Protein, MGC57346-CRHR1 Protein, corticotropin releasing hormone receptor 1 Protein, corticotropin releasing hormone receptor 1, gene 2 S homeolog Protein, corticotropin-releasing factor receptor 1 Protein, LINC02210-CRHR1 readthrough Protein, CRHR1 Protein, Crhr1 Protein, crhr1.2.S Protein, LOC610380 Protein, LOC100065598 Protein, LINC02210-CRHR1 Protein, crhr1 Protein
- Background
- G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
- Molecular Weight
- 13.1 kDa
- UniProt
- P34998
- Pathways
- Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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