Browse our anti-LTBP4 (LTBP4) Antibodies

Full name:
anti-Latent Transforming Growth Factor beta Binding Protein 4 Antibodies (LTBP4)
On are 6 Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4) Antibodies from 5 different suppliers available. Additionally we are shipping LTBP4 Kits (4) and and many more products for this protein. A total of 13 LTBP4 products are currently listed.
2310046A13Rik, ARCL1C, LTBP-4, LTBP4L, LTBP4S
list all antibodies Gene Name GeneID UniProt
LTBP4 8425 Q8N2S1
LTBP4 108075 Q8K4G1
LTBP4 292734  

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Top referenced anti-LTBP4 Antibodies

  1. Human Polyclonal LTBP4 Primary Antibody for IF (p), IHC (p) - ABIN714626 : Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. in Nature communications 2016 (PubMed)

More Antibodies against LTBP4 Interaction Partners

Human Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4) interaction partners

  1. Studied the potential role of LTBP-4 in scleroderma through clinical, in vivo and in vitro studies. Results suggest that LTBP-4 protein level is increased in plasma and skin tissue of scleroderma patients; found LTBP-4 to be a potential biomarker to differentiate systemic scleroderma (SSc (show CYP11A1 Antibodies)) from localized scleroderma (LSc (show ARHGEF1 Antibodies)) patients.

  2. The LTBP4 VTTT allele is associated with increased risk of dilated cardiomyopathy in European Americans. LTBP4 protein with the IAAM residues bound more latent TGFbeta (show TGFB1 Antibodies) compared to the LTBP4 VTTT protein.

  3. Our results show that LTBP4 interacts with TGFBR2 (show TGFBR2 Antibodies) and stabilizes TGFbeta (show TGFB1 Antibodies) receptors by preventing their endocytosis and lysosomal degradation in a ligand-dependent and receptor kinase activity-dependent manner.

  4. We show that corticosteroid treatment and the IAAM haplotype of the LTBP4 gene are significantly associated with prolonged ambulation in patients with Duchenne muscular dystrophy (show DMD Antibodies)

  5. In the mdx (show DMD Antibodies) mouse model of Duchenne muscular dystrophy (show DMD Antibodies), the human LTBP4 transgene exacerbated muscular dystrophy symptoms and resulted in weaker muscles with an increased inflammatory infiltrate.

  6. In Caucasians with Duchenne muscular dystrophy (show DMD Antibodies) and LTBP4 genotype there was a protective effect on age at loss of ambulation.

  7. It recruits elastin (show ELN Antibodies) to microfibrils via fibulin-5 (show FBLN5 Antibodies).

  8. LTBP4 haplotype influences age at loss of ambulation, and should be considered in the management of Duchenne muscular dystrophy (show DMD Antibodies) patients.

  9. Latent transforming growth factor beta-binding protein 4 is downregulated in esophageal cancer via promoter methylation.

  10. Data indicate mutations of FBLN4 (show FBLN4 Antibodies), FBLN5 (show FBLN5 Antibodies), and LTBP4 in 12 probands presenting with type 1 recessive cutis laxa.

Mouse (Murine) Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4) interaction partners

  1. we found that myostatin (show MSTN Antibodies) forms a complex with LTBP4 and that overexpression of LTBP4 led to a decrease in myostatin (show MSTN Antibodies) levels. LTBP4 also interacted with TGFbeta (show TGFB1 Antibodies) and GDF11 (show GDF11 Antibodies), a protein highly related to myostatin (show MSTN Antibodies). These data identify LTBP4 as a multi-TGFbeta (show TGFB1 Antibodies) family ligand binding protein with the capacity to modify muscle disease through overexpression

  2. Ltbp-4L expression is essential for incorporation of fibulin-4 (show FBLN4 Antibodies) into the extracellular matrix.

  3. These results are consistent with a role for TGFbeta2 in lung septation and for Ltbp4 in regulating fibulin-5 (show FBLN5 Antibodies) dependent elastic fiber assembly.

  4. data suggest a unique function for LTBP-4 during elastic fibrogenesis, making it a potential therapeutic target for elastic fiber regeneration

  5. The lack of LTBP4-mediated targeting in malignant mammary tumor tissues may lead to a possible modification of TGF-ss1 and BMP bioavailability and function.

  6. These data indicate that LTBP-3 and -4 perform partially overlapping functions only in the lungs.

  7. an insertion/deletion polymorphism of 36 bp in the coding region of the Ltbp4 was found in an animal model of muscular dystrophy

  8. LTBP-4 has a role in targeting and activation of TGF-beta1 (show TGFB1 Antibodies) which regulates BMP-4 (show BMP4 Antibodies) signaling in mouse lung

  9. Results indicate taht there are two separate functions of LTBP-4, as a regulator of elastic fiber assembly and of TGF-beta (show TGFB1 Antibodies) levels in lungs.

LTBP4 Antigen Profile

Antigen Summary

The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LTBP4

  • latent transforming growth factor beta binding protein 4 (LTBP4) antibody
  • latent transforming growth factor beta binding protein 4 (ltbp4) antibody
  • latent transforming growth factor beta binding protein 4 (Ltbp4) antibody
  • 2310046A13Rik antibody
  • ARCL1C antibody
  • LTBP-4 antibody
  • LTBP4L antibody
  • LTBP4S antibody

Protein level used designations for LTBP4

latent transforming growth factor beta binding protein 4 , latent-transforming growth factor beta-binding protein 4-like , latent transforming growth factor-beta binding protein 4L , latent-transforming growth factor beta-binding protein 4 , LTBP-4

100018129 Monodelphis domestica
100488208 Xenopus (Silurana) tropicalis
8425 Homo sapiens
108075 Mus musculus
292734 Rattus norvegicus
444849 Canis lupus familiaris
100848191 Bos taurus
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