LTBP4 antibody (C-Term)

Catalog No. ABIN2789916

The Rabbit Polyclonal anti-LTBP4 antibody (ABIN2789916) specifically detects LTBP4 in WB. The antibody is reactive with Human, Dog, Horse, Rabbit and Cow samples.

Quick Overview for LTBP4 antibody (C-Term) (ABIN2789916)

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Reactivity: Human, Dog, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTBP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LTBP4 Antibody

Binding Specificity: C-Term

Sequence: GGPYGESEAP APPGPGTRWP YRSRDTRRSF PEPEEPPEGG SYAGSLAEPY

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 86%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against LTBP4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LTBP4

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LTBP4

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Alternative Name: LTBP4

Background: The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: FBXO6, HCVgp1, FRAT1, UBC, RAC1, FBLN1, CRY1, GFI1B, ATN1, ITSN2, CRKL, ATXN7, CACNA1A, TGFB1, TRIB3,
Protein Size: 636

Molecular Weight: 69 kDa

Gene ID: 8425

Pathways: Hormone Transport, Growth Factor Binding