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Browse our CBP Proteins (CREBBP)

Full name:
CREB Binding Protein Proteins (CREBBP)
On www.antibodies-online.com are 11 CREB Binding Protein (CREBBP) Proteins from 6 different suppliers available. Additionally we are shipping CBP Antibodies (141) and CBP Kits (13) and many more products for this protein. A total of 172 CBP products are currently listed.
Synonyms:
AW558298, CBBM, Cbp, CBP/p300, COD5, crebbp, F730007C19Rik, hmm291030, KAT3A, Nejire, p300/CBP, Pag, RCP, ROP, RSTS, RTS
list all proteins Gene Name GeneID UniProt
CREBBP 1387 Q92793
CREBBP 12914  
CREBBP 54244  

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CBP Proteins (CREBBP) by Origin

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Human CREB Binding Protein (CREBBP) interaction partners

  1. CREBBP mutations might assist in enhancing oncogenic RAS signaling in acute lymphoblastic leukemia but do not alter response to MEK (show MAP2K1 Proteins) inhibitors.

  2. Mutations identified in patients with and without classical Rubinstein-Taybi syndrome lead to skipping of exon20 of CREBBP.

  3. LVAVA haplotype of the OPN1LW gene and MVAVA haplotype of the OPN1MW (show OPN1MW Proteins) gene cause apparently nonsyndromic high myopia in young patients but lead to progressive cone-rod dystrophy with deuteranopia and protanopia in middle-aged patients corresponding to a previously unknown disease course.

  4. Findings show that OPN1LW mutations underlie the cone dysfunction in all of the subjects tested, the color vision defect can be caused either by the same mutation or a gene rearrangement at the same locus

  5. Data suggest that insights into dimerization interface of red cone opsin should aid investigations of the structure and function of GPCR cell signaling.

  6. Letter/Case Report: duplication mutation, c.5837dupC (p.P1947TfsX19), in CREBBP in patient with Rubinstein-Taybi syndrome with multiple pilomatricomas.

  7. C646 treatment attenuated ETV1 protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 may serve as novel antineoplastic targets and that use of the selective HAT inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors.

  8. The CREBBP gene is believed to be the dosage-sensitive critical gene responsible for the reciprocal duplication and deletion syndrome

  9. Results show that CREBBP was the most frequent target of epigenetic modification in juvenile myelomonocytic leukemia.

  10. Data show that mutation of key residues in the binding site abolishes binding and that small ubiquitin-like modifier 1 (SUMO1 (show SUMO1 Proteins)) can simultaneously and non-cooperatively bind both the ZZ domain and a canonical SIM (show SIM2 Proteins) motif of CREB-binding protein (CBP/p300).

Mouse (Murine) CREB Binding Protein (CREBBP) interaction partners

  1. Brd3 (show BRD3 Proteins) knockout significantly decreased the recruitment of acetylase CBP to IL6 (show IL6 Proteins) gene promoter, and the acetylation level of histone3 within IL6 (show IL6 Proteins) gene promoter was repressed.

  2. Inhibition of hypothalamic Cbp results in profound obesity and impaired glucose homeostasis, increased food intake, and decreased body temperature. In addition, these changes are accompanied by molecular evidence in the hypothalamus for impaired leptin (show LEP Proteins) and insulin (show INS Proteins) signaling, a shift from glucose to lipid metabolism, and decreased Pomc (show POMC Proteins) mRNA, with no effect on locomotion.

  3. our findings illustrate that Cbp is an important regulator of Csk (show CSK Proteins) recruitment to the SFK Lyn (show LYN Proteins) in Eporesponsive erythroid cells.

  4. Study demonstrates that CBP binds directly to RNAs in vivo and in vitro. RNAs bound to CBP in vivo include a large number of eRNAs. Using steady-state histone acetyltransferase (HAT) assays, study shows that an RNA binding region in the HAT domain of CBP-a regulatory motif unique to CBP/p300-allows RNA to stimulate CBP's HAT activity.

  5. We focused on genomic loci bound by the neuronal activity-regulated coactivator CREBBP, and we measured enhancer and promoter activities both before and after neuronal activation

  6. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4 (show DLL4 Proteins)-NOTCH1 (show NOTCH1 Proteins) Signaling

  7. Data suggest that mechanisms involving CBP histone acetyltransferase-mediated lysine acetylation of nuclear proteins support selectively long-term encoding in the medial prefrontal cortex circuits

  8. Ajuba (show AJUBA Proteins) recruits p300/CBP via its LIM (show PDLIM5 Proteins) domain and facilitates p300/CBP binding to PPARg (show PPARG Proteins). Moreover, Ajuba (show AJUBA Proteins), PPARg (show PPARG Proteins), p300/CBP can cooperatively occupy the PPARg (show PPARG Proteins) target promoters and concomitantly increases histone acetylation at these loci.

  9. Recognition of the disordered TP53 (show TP53 Proteins) transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.

  10. Results indicate that loss of CBP CH1 domain function contributes to Rubinstein-Taybi Syndrome (RTS (show RECQL4 Proteins)), and possibly Autism spectrum disorders (ASDs), and that this domain plays an essential role in normal motor function, cognition and social behavior.

CBP (CREBBP) Protein Profile

Protein Summary

This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness.

Alternative names and synonyms associated with CBP (CREBBP)

  • CREB binding protein (CREBBP)
  • CREB binding protein (crebbp-b)
  • CREB binding protein (Crebbp)
  • opsin 1 (cone pigments), long-wave-sensitive (OPN1LW)
  • phosphoprotein associated with glycosphingolipid microdomains 1 (Pag1)
  • AW558298 protein
  • CBBM protein
  • Cbp protein
  • CBP/p300 protein
  • COD5 protein
  • crebbp protein
  • F730007C19Rik protein
  • hmm291030 protein
  • KAT3A protein
  • Nejire protein
  • p300/CBP protein
  • Pag protein
  • RCP protein
  • ROP protein
  • RSTS protein
  • RTS protein

Protein level used designations for CREB Binding Protein Proteins (CREBBP)

CREB binding protein (Rubinstein-Taybi syndrome) , CREB-binding protein , cone dystrophy 5 (X-linked) , long-wave-sensitive opsin 1 , red cone photoreceptor pigment , red-sensitive opsin , Csk-binding protein , phosphoprotein associated with glycosphingolipid-enriched microdomains 1 , phosphoprotein transmembrane adaptor 1 , phosphoprotein-associated with GEMs , transmembrane phosphoprotein Cbp

GENE ID SPECIES
467891 Pan troglodytes
495689 Xenopus laevis
704331 Macaca mulatta
100123220 Nasonia vitripennis
1387 Homo sapiens
12914 Mus musculus
54244 Rattus norvegicus
505453 Bos taurus
479866 Canis lupus familiaris
5956 Homo sapiens
94212 Mus musculus
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