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CBP Protein (GST tag)

CREBBP Origin: Human Host: Insect cells (Sf9) Recombinant >90% WB
Rockland
Catalog No. ABIN6699731
Supplier Product No.: 009-001-s26s
  • Target See all CBP (CREBBP) Proteins
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 2
    Human
    Source
    • 8
    • 1
    • 1
    Insect cells (Sf9)
    Purification tag / Conjugate
    This CBP protein is labelled with GST tag.
    Application
    Western Blotting (WB)
    Supplier Product No.
    009-001-s26s
    Supplier
    Rockland
    Purpose
    KAT3A (CREBBP) recombinant protein-GST fusion protein
    Purification
    Recombinant human KAT3A (518-1207) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry.
    Purity
    >90%
    Top Product
    Discover our top product CREBBP Protein
  • Application Notes

    Western_Blot_Dilution: User Optimized

    Application_Note: KAT3A Protein is suitable for use in Western Blot. Expect a band approximately ~65 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1 μg/μL
    Buffer
    KAT3A Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Alternative Name
    CREBBP (CREBBP Products)
    Background

    Synonyms: CREBBP, CBP, KAT3A, RSTS, CREB-binding protein

    Background: KAT3A has intrinsic histone acetyltransferase activity that acts as a scaffold to stabilize additional protein interactions with the transcription complex and acetylates both histone and non-histone proteins. KAT3A (CREBBP) expressed as a nuclear protein that binds to cAMP-response element binding protein (CREB) and involved in the transcriptional coactivation of many different transcription factors. KAT3A plays a main role in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition (1). KAT3A also plays a critical role in the transmission of inductive signals from cell surface receptors to the transcriptional apparatus (2). KAT3A Protein is ideal for investigators involved in Signaling Proteins, Acetyl/Methyltransferase Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, and PKA/PKC Pathway research.

    NCBI Accession
    NM_004380
    Pathways
    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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