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Browse our CSF2 Proteins (CSF2)

Full name:
Colony Stimulating Factor 2 (Granulocyte-Macrophage) Proteins (CSF2)
On are 220 Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) Proteins from 27 different suppliers available. Additionally we are shipping CSF2 Antibodies (458) and CSF2 Kits (177) and many more products for this protein. A total of 877 CSF2 products are currently listed.
CSF, CSF2, Csfgm, Gm-csf, Gmcsf, MGI-IGM
list all proteins Gene Name GeneID UniProt
CSF2 1437 P04141
CSF2 12981 P01587
CSF2 116630 P48750

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CSF2 Proteins (CSF2) by Origin

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Top referenced CSF2 Proteins

  1. Mouse (Murine) CSF2 Protein expressed in Escherichia coli (E. coli) - ABIN1305143 : Gough, Gough, Metcalf, Kelso, Grail, Nicola, Burgess, Dunn: Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor. in Nature 1984 (PubMed)
    Show all 6 references for ABIN1305143

  2. Rat (Rattus) CSF2 Protein expressed in Human Cells - ABIN2009043 : Ebner, Bandion, Binder, de Martin, Schmid: GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta. in Blood 2003 (PubMed)
    Show all 5 references for ABIN2009043

  3. Human CSF2 Protein expressed in Human Cells - ABIN2001912 : Volmar, Ait-Ghezala, Frieling, Paris, Mullan: The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production. in Cytokine 2008 (PubMed)
    Show all 5 references for ABIN2001912

  4. Mouse (Murine) CSF2 Protein expressed in Human Cells - ABIN2008546 : Frolova, Dolganov, Mazo, Smirnov, Copeland, Stewart, OBrien, Dean: Linkage mapping of the human CSF2 and IL3 genes. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for ABIN2008546

  5. Rat (Rattus) CSF2 Protein expressed in Escherichia coli (E. coli) - ABIN809714 : Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007 (PubMed)
    Show all 2 references for ABIN809714

  6. Human CSF2 Protein expressed in HEK-293 Cells - ABIN2181169 : Ait-ghezala, Abdullah, Volmar, Paris, Luis, Quadros, Mouzon, Mullan, Keegan, Parrish, Crawford, Mathura, Mullan: Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease. in Cytokine 2008 (PubMed)

  7. Human CSF2 Protein expressed in Escherichia coli (E. coli) - ABIN934919 : Spatz, Eibl, Hink, Wolf, Fischer, Mayr, Schernthaner, Eibl: Impaired primary immune response in type-1 diabetes. Functional impairment at the level of APCs and T-cells. in Cellular immunology 2003 (PubMed)

More Proteins for CSF2 Interaction Partners

Horse (Equine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. TRAF6 (show TRAF6 Proteins) is also required for GM-CSF-induced ubiquitination and activation of Akt (show AKT1 Proteins).

Human Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. Letter: Knockdown of either filaggrin (show FLG Proteins) or loricrin (show LOR Proteins) increases the productions of interleukin (IL)-1alpha, IL-8 (show IL8 Proteins), IL-18 (show IL18 Proteins) and granulocyte macrophage colony-stimulating factor in stratified human keratinocytes.

  2. Impaired RASGRF1 (show RASGRF1 Proteins)/ERK (show EPHB2 Proteins)-mediated GM-CSF response characterizes CARD9 (show CARD9 Proteins) deficiency in French-Canadians.

  3. Honokiol could possess potential anti-inflammatory effects and inhibits TNF-alpha (show TNF Proteins)-induced IL-1beta (show IL1B Proteins), GM-CSF and IL-8 (show IL8 Proteins) production in PBMCs from rheumatoid arthritis patients.

  4. The canonical NFkappaB (show NFKB1 Proteins) signaling in fibroblasts, but not in tumor cells, was shown to be responsible for the induced and constitutive CSF2 expression.

  5. GM-CSF primes IL-13 (show IL13 Proteins) production by macrophages via PAR-2 (show F2RL1 Proteins).

  6. analysis of an IL2RA (show IL2RA Proteins) polymorphism that controls GM-CSF production in human TH cells

  7. NFKBIZ (show NFKBIZ Proteins) gene knockdown in bronchial epithelial cells suppresses the release of IL-1b (show IL1B Proteins)-induced IL-6 (show IL6 Proteins) and GMCSF.

  8. CFH (show CFH Proteins) Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye.

  9. Influenza infection stimulates the secretion of IL-8 (show IL8 Proteins) and GM-CSF by alveolar epithelial cells.

  10. Periodic fever, aphthous stomatitis, pharyngitis and cervical adenopathy syndrome febrile episodes are characterized by activation of GM-CSF and IL-8 (show IL8 Proteins) with Th1 (show TH1L Proteins) skewing.

Cow (Bovine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 (show CXCL10 Proteins) and GM-CSF gene transcription.

  2. Data suggest exposure to maternal CSF2 from D5-D7 of development is fundamentally different for female/male blastocysts with respect to embryo elongation, characteristics of transcriptome/methylome, and endometrial interferon tau secretion at D15 (show MRPL16 Proteins).

  3. The increase in calving rate caused by CSF2 treatment involves, in part, more extensive development of extraembryonic membranes and capacity of the conceptus to secrete IFNT2 at day 15 of pregnancy.

  4. immunolocalization studies confirmed the presence of granulocyte-macrophage colony stimulating factor(GM-CSF) in the germ cell line in bovine and human testes and addition of GM-CSF enhances several parameters of sperm motility

  5. the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 (show PTGS2 Proteins) and GM-CSF during the peri (show PLIN1 Proteins)-attachment period in the cow.

  6. CSF2 affect embryonic development and enhance embryo competence for posttransfer survival.

Mouse (Murine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. Evi1 (show MECOM Proteins)(+)DA-3 cells modified to express an intracellular form of GM-CSF, acquired growth factor independence and transplantability and caused an overt leukemia in syngeneic hosts, without increasing serum GM-CSF levels.

  2. IL-23 (show IL23A Proteins)-induced GM-CSF mediates the pathogenicity of CD4 (show CD4 Proteins)(+) T cells in experimental autoimmune myocarditis.

  3. GM-CSF accelerated the G1/S phase transition in EPCs by upregulating the expression of cyclins D1 and E.

  4. Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Macrophage Colony Stimulating Factor (M-CSF (show CSF1R Proteins)) Grown Macrophages Derived from Murine Bone Marrow Cells

  5. host RNF13 (show RNF13 Proteins) affects the concentration of GM-CSF in tumor-bearing lungs

  6. Sc CW-derived BG stimulated the late and strong expression of Csf2 in a dectin-1 (show CLEC7A Proteins)-dependent manner, they remain poor inducers of chemokine (show CCL1 Proteins) and cytokine production in murine macrophages.

  7. GM-CSF and uPA (show PLAU Proteins) are required for Porphyromonas gingivalis-induced alveolar bone loss in a mouse periodontitis model.

  8. These findings identify GM-CSF as central to the protective immune response that prevents progressive fungal disease

  9. IL-23 (show IL23A Proteins)/IL-1 (show IL1A Proteins)/IFNgamma/TNFalpha (show TNF Proteins)/T-bet/Eomesodermin (show EOMES Proteins)-driven circuit drives GM-CSF/IFNgamma-producing Th17 cell development.

  10. -12-modulated Th1 (show HAND1 Proteins) cells readily produce IFN-gamma (show IFNG Proteins) and GM-CSF in the CNS of mice and induce a severe form of EAE via an IL-23 (show IL23A Proteins)-independent pathway.

Pig (Porcine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. CSF2 stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (show MAPK1 Proteins)-dependent MTOR (show FRAP1 Proteins) signal transduction cascades.

Goat Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. Data indicate that differentially expressed IL-17 (show IL17A Proteins), IL-22 (show IL22 Proteins), and IL-23 (show IL23A Proteins) levels are associated with K-ras (show HRAS Proteins) in a stage-specific fashion along colorectal cancer progression and an association was established between mutant K-ras (show HRAS Proteins) and GM-CSF and IFN-gamma (show IFNG Proteins).

CSF2 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.

Alternative names and synonyms associated with CSF2

  • granulocyte-macrophage colony-stimulating-factor (GM-CSF)
  • colony stimulating factor 2 (granulocyte-macrophage) (CSF2)
  • granulocyte-macrophage colony-stimulating factor (GM-CSF)
  • colony stimulating factor 2 (granulocyte-macrophage) (Csf2)
  • granulocyte-macrophage colony stimulating factor (GM-CSF)
  • CSF protein
  • CSF2 protein
  • Csfgm protein
  • Gm-csf protein
  • Gmcsf protein
  • MGI-IGM protein

Protein level used designations for CSF2

granulocyte-macrophage colony-stimulating factor , colony stimulating factor 2 (granulocyte-macrophage) , CSF , molgramostin , sargramostim , colony-stimulating factor , granulocyte-macrophage colony stimulating factor 2 , put. GM-CSF , GM-CSF , granulate-macrophage stimulating factor , granulocyte-macrophage stimulation factor

100033981 Equus caballus
100126743 Papio anubis
100137216 Papio anubis
471627 Pan troglodytes
1437 Homo sapiens
281095 Bos taurus
12981 Mus musculus
116630 Rattus norvegicus
443400 Ovis aries
403923 Canis lupus familiaris
397208 Sus scrofa
416325 Gallus gallus
100135508 Cavia porcellus
493805 Felis catus
574371 Macaca mulatta
100861208 Capra hircus
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