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Mouse (Murine) EPO Protein expressed in Escherichia coli (E. coli) - ABIN1305139
JACOBSON, GOLDWASSER, FRIED, PLZAK: Role of the kidney in erythropoiesis. in Nature 1957
Show all 6 Pubmed References
Human EPO Protein expressed in Wheat germ - ABIN1352975
Zhang, Wang, Wang, Shi, Deng, Fu: rhEPO/EPO discrimination with ultrasensitive electrochemical biosensor based on sandwich-type nano-Au/ZnO sol-gel/nano-Au signal amplification. in Biosensors & bioelectronics 2013
Data show that erythropoietin (EPO) mRNA was upregulated in the lung, from the metamorphic climax (stage 60) onward.
EPO induces an EMT (show ITK Proteins)-like process in mammary non-tumorigenic epithelial cells
these results suggested that quercetin's cytoprotective effects in HepG2 cells are mediated via EPO production.
Serum Epo and VEGF may be markers of severity of hypoxia-ischaemia and brain injury as they are closely related to hypoxic exposure.
CIS (show CISH Proteins) interacted with phosphorylated EpoR (show EPOR Proteins) at Y401, which was critical for the activation of STAT5 (show STAT5A Proteins) and ERK (show EPHB2 Proteins).
EPO dependent regulation pathway of FGF23 (show FGF23 Proteins) gene expression
Fetal plasma EPO concentrations are selectively increased in monochorionic twin pregnancies with intrauterine growth restriction.
SYK (show SYK Proteins) mediates the actions of EPO and GM-CSF (show CSF2 Proteins) and coordinates with TGF-beta (show TGFB1 Proteins) in erythropoiesis.
this study shows that EPO is involved in the pathogenesis of sepsis-induced acute kidney injury
Erythropoietin is superior to the standard prognostic scores in predicting 28-day mortality in patients with acute-on-chronic liver failure.
EPO levels were also found correlated positively with heme, TNF-alpha (show TNF Proteins), IL-10 (show IL10 Proteins), IP-10 (show CXCL10 Proteins) and MCP-1 (show CCL2 Proteins) during cerebral malaria.
data identify the PHD2 (show EGLN1 Proteins):HIF-2alpha:EPO axis as a so far unknown regulator of osteohematology by controlling bone homeostasis.
these data provide strong evidence for a role for G-CSF (show CSF3 Proteins) in the development of ACI after burn injury through suppression of EPO signaling in bone marrow erythroid cells.
Data indicated the possible involvement of Jak2 (show JAK2 Proteins)/STAT3 (show STAT3 Proteins)/STAT6 (show STAT6 Proteins) pathway in the augmentation of EPO on M2 polarization. These results improved the understanding of the immunoregulatory capacity of EPO on macrophages, which might optimize the therapeutic modalities of EPO.
The lack of effect of erythropoietin on hepcidin (show HAMP Proteins) expression in mask mice can not be explained by changes in erythroferrone synthesis, as splenic erythroferrone content increased after erythropoietin administration in both C57BL/6 and mask mice.
EPO expression in myoblasts and myotubes is increased by hypoxia and exercise
these findings define a cis (show CISH Proteins)-regulatory enhancer network for Epo signaling during erythropoiesis, and provide the framework for future studies involving the interplay of epigenetics and Epo signaling.
FOXD1 (show FOXD1 Proteins) lineage renal interstitial cells consist of distinct subpopulations that differ in their responsiveness to Phd2 (show EGLN1 Proteins) inactivation and thus regulation of HIF-2 activity and EPO production under hypoxia or conditions of pharmacologic or genetic PHD (show PDC Proteins) inactivation.
This study suggests a possible role of EPO in embryonic endodermal development and a new agent for directing the differentiation into endodermal lineages like pancreatic beta-cells.
Smad1 (show SMAD1 Proteins) and Smad5 (show SMAD5 Proteins) have overlapping functions to govern hepcidin (show HAMP Proteins) transcription. Moreover, erythropoietin and erythroferrone target Smad1 (show SMAD1 Proteins)/5 signaling and require Smad1 (show SMAD1 Proteins)/5 to suppress hepcidin (show HAMP Proteins) expression.
EPO role in the glucose homeostasis, thermogenesis and endocrine function of classical brown adipose tissue
EPO might play a role as a survival factor or as a mitogen in developing cartilage tissue.
Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass.
A single intramuscular injection of recombinant adeno (show ADORA2A Proteins)-associated virus carrying mutant Epo (R76E) preserves retinal ganglion cells and visual function in glaucomatous mice.
The zebrafish epo cDNA was cloned and the expression of zepo mRNA was mainly in the heart and liver.
characterization of zebrafish epo and epor (show EPOR Proteins) demonstrates the conservation of an ancient program that ensures proper red blood cell numbers during normal homeostasis and under hypoxic conditions
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.