Browse our EPO Proteins (EPO)

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Erythropoietin Proteins (EPO)
On are 85 Erythropoietin (EPO) Proteins from 15 different suppliers available. Additionally we are shipping EPO Antibodies (370) and EPO Kits (116) and many more products for this protein. A total of 584 EPO products are currently listed.
list all proteins Gene Name GeneID UniProt
EPO 2056 P01588
EPO 24335 P29676
EPO 13856 P07321

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EPO Proteins (EPO) by Origin

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Top referenced EPO Proteins

  1. Mouse (Murine) EPO Protein expressed in CHO Cells - ABIN2666935 : Shoemaker, Mitsock: Murine erythropoietin gene: cloning, expression, and human gene homology. in Molecular and cellular biology 1986 (PubMed)
    Show all 8 references for 2666935

  2. Rat (Rattus) EPO Protein expressed in CHO Cells - ABIN2666807 : Nagao, Suga, Okano, Masuda, Narita, Ikura, Sasaki: Nucleotide sequence of rat erythropoietin. in Biochimica et biophysica acta 1992 (PubMed)
    Show all 6 references for 2666807

  3. Mouse (Murine) EPO Protein expressed in Escherichia coli (E. coli) - ABIN1305139 : JACOBSON, GOLDWASSER, FRIED, PLZAK: Role of the kidney in erythropoiesis. in Nature 1957 (PubMed)
    Show all 6 references for 1305139

  4. Human EPO Protein expressed in CHO Cells - ABIN2666933 : Chin, Yu, Beleslin-Cokic, Liu, Shen, Mohrenweiser, Noguchi: Production and processing of erythropoietin receptor transcripts in brain. in Brain research. Molecular brain research 2000 (PubMed)
    Show all 6 references for 2666933

  5. Human EPO Protein expressed in Wheat germ - ABIN1352975 : Zhang, Wang, Wang, Shi, Deng, Fu: rhEPO/EPO discrimination with ultrasensitive electrochemical biosensor based on sandwich-type nano-Au/ZnO sol-gel/nano-Au signal amplification. in Biosensors & bioelectronics 2013 (PubMed)

  6. Human EPO Protein expressed in HEK-293 Cells - ABIN2181033 : FRIED, GOLDWASSER, JACOBSON, PLZAK: Studies on erythropoiesis. III. Factors controlling erythropoietin production. in Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1957 (PubMed)

More Proteins for EPO Interaction Partners

Xenopus laevis Erythropoietin (EPO) interaction partners

  1. Data show that erythropoietin (EPO) mRNA was upregulated in the lung, from the metamorphic climax (stage 60) onward.

Human Erythropoietin (EPO) interaction partners

  1. Erythropoietin is superior to the standard prognostic scores in predicting 28-day mortality in patients with acute-on-chronic liver failure.

  2. EPO levels were also found correlated positively with heme, TNF-alpha (show TNF Proteins), IL-10 (show IL10 Proteins), IP-10 (show CXCL10 Proteins) and MCP-1 (show CCL2 Proteins) during cerebral malaria.

  3. CK1delta enhances EPO secretion from liver cancer cells under hypoxia by modifying HIF-2alpha (show EPAS1 Proteins) and promoting its nuclear accumulation.

  4. Three single nucleotide polymorphisms are associated with increased risk of diabetic retinopathy in a Chinese Han population.

  5. Pharmacokinetic animal studies revealed strongly 15.6-fold plasma half-life extension for the PASylated EPO (83.16 +/- 13.28 h) in comparison to epoetin alpha (8.5 +/- 2.4 h) and darbepoetin alpha (25.3 +/- 2.2h).

  6. Secreted MIR122 reached the kidney and reduced expression of erythropoietin, contributing to inflammation-induced anemia.

  7. this paper shows that Epo could directly down-regulate pro-inflammatory T cell responses without affecting T cell activation status

  8. findings suggest that erythropoietin levels in anemia of unknown etiology, although elevated, remain inappropriately low, particularly when compared with other forms of anemia. This suggests a relative erythropoietin deficiency or a blunted erythroid cell response.

  9. Plasma IGFBP-1 (show IGFBPI Proteins) was significantly associated with plasma EPO concentration in acute kidney injury, suggesting an unknown mechanism related to systemic stress conditions for EPO regulation in AKI.

  10. Our results suggest that EPO/EPOR (show EPOR Proteins) pathway promotes gastric cancer formation, proliferation, migration, and decreases apoptosis

Mouse (Murine) Erythropoietin (EPO) interaction partners

  1. FOXD1 (show FOXD1 Proteins) lineage renal interstitial cells consist of distinct subpopulations that differ in their responsiveness to Phd2 (show EGLN1 Proteins) inactivation and thus regulation of HIF-2 activity and EPO production under hypoxia or conditions of pharmacologic or genetic PHD (show PDC Proteins) inactivation.

  2. This study suggests a possible role of EPO in embryonic endodermal development and a new agent for directing the differentiation into endodermal lineages like pancreatic beta-cells.

  3. Smad1 (show SMAD1 Proteins) and Smad5 (show SMAD5 Proteins) have overlapping functions to govern hepcidin (show HAMP Proteins) transcription. Moreover, erythropoietin and erythroferrone target Smad1 (show SMAD1 Proteins)/5 signaling and require Smad1 (show SMAD1 Proteins)/5 to suppress hepcidin (show HAMP Proteins) expression.

  4. EPO role in the glucose homeostasis, thermogenesis and endocrine function of classical brown adipose tissue

  5. Epo transcription in brain pericytes was HIF-2 dependent and cocontrolled by PHD2 (show EGLN1 Proteins) and PHD3 (show EGLN3 Proteins), oxygen- and 2-oxoglutarate-dependent prolyl-4-hydroxylases that regulate HIF activity.

  6. This study showed that polycythemia alone and increased levels of plasma Epo blunt the hypercapnic ventilatory response (HCVR); mice with an augmented level of cerebral Epo also had a decreased HCVR.

  7. Epo gene regulation in EPO-producing cells is a complex process that utilizes multiple regulatory influences.

  8. this study shows that EPO could directly promote tumor progression via EPO receptor-expressing macrophages

  9. pharmacologic downstream inhibition of the Bmp-Smad (show SMAD1 Proteins) pathway by dorsomorphin, which targets the BMP receptors, improves the hepcidin (show HAMP Proteins) responsiveness to EPO in Tmprss6 (show TMPRSS6 Proteins) KO mice.

  10. In mice, inflammation increases blood levels of MIR122, which reduces expression of Epo in the kidney.

Pig (Porcine) Erythropoietin (EPO) interaction partners

  1. EPO might play a role as a survival factor or as a mitogen in developing cartilage tissue.

  2. Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass.

Rhesus Monkey Erythropoietin (EPO) interaction partners

  1. A single intramuscular injection of recombinant adeno (show ADORA2A Proteins)-associated virus carrying mutant Epo (R76E) preserves retinal ganglion cells and visual function in glaucomatous mice.

Zebrafish Erythropoietin (EPO) interaction partners

  1. The zebrafish epo cDNA was cloned and the expression of zepo mRNA was mainly in the heart and liver.

  2. characterization of zebrafish epo and epor (show EPOR Proteins) demonstrates the conservation of an ancient program that ensures proper red blood cell numbers during normal homeostasis and under hypoxic conditions

EPO Protein Profile

Protein Summary

This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.

Alternative names and synonyms associated with EPO

  • erythropoietin (EPO)
  • erythropoietin (epo)
  • erythropoietin (Epo)
  • EP protein
  • EPO protein
  • MVCD2 protein

Protein level used designations for Erythropoietin Proteins (EPO)

erythropoietin , epoetin

463609 Pan troglodytes
100494034 Xenopus (Silurana) tropicalis
100505445 Xenopus laevis
2056 Homo sapiens
24335 Rattus norvegicus
404002 Canis lupus familiaris
13856 Mus musculus
397249 Sus scrofa
100033849 Equus caballus
100008786 Oryctolagus cuniculus
280784 Bos taurus
493801 Felis catus
443302 Ovis aries
100712648 Cavia porcellus
719294 Macaca mulatta
100004455 Danio rerio
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