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Mouse (Murine) EPO Protein expressed in CHO Cells - ABIN2666935
Shoemaker, Mitsock: Murine erythropoietin gene: cloning, expression, and human gene homology. in Molecular and cellular biology 1986
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Human EPO Protein expressed in CHO Cells - ABIN2666933
Chin, Yu, Beleslin-Cokic, Liu, Shen, Mohrenweiser, Noguchi: Production and processing of erythropoietin receptor transcripts in brain. in Brain research. Molecular brain research 2000
Show all 6 references for ABIN2666933
Rat (Rattus) EPO Protein expressed in CHO Cells - ABIN2666807
Nagao, Suga, Okano, Masuda, Narita, Ikura, Sasaki: Nucleotide sequence of rat erythropoietin. in Biochimica et biophysica acta 1992
Show all 6 references for ABIN2666807
Mouse (Murine) EPO Protein expressed in Escherichia coli (E. coli) - ABIN1305139
JACOBSON, GOLDWASSER, FRIED, PLZAK: Role of the kidney in erythropoiesis. in Nature 1957
Show all 6 references for ABIN1305139
Human EPO Protein expressed in Wheat germ - ABIN1352975
Zhang, Wang, Wang, Shi, Deng, Fu: rhEPO/EPO discrimination with ultrasensitive electrochemical biosensor based on sandwich-type nano-Au/ZnO sol-gel/nano-Au signal amplification. in Biosensors & bioelectronics 2013
Human EPO Protein expressed in HEK-293 Cells - ABIN2181033
FRIED, GOLDWASSER, JACOBSON, PLZAK: Studies on erythropoiesis. III. Factors controlling erythropoietin production. in Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1957
Data show that erythropoietin (EPO) mRNA was upregulated in the lung, from the metamorphic climax (stage 60) onward.
Suggest that hypoxia prevents EPO suppression, and exaggerates the plasma volume reduction induced by bed rest.
Inadequate erythropoietin response may partly explain anemia in anorexia nervosa.
these findings suggest that TGF-beta (show TGFB1 Proteins) suppression and EPO stimulation promote erythropoiesis of CD34 (show CD34 Proteins)(+)CD31 (show HBA1 Proteins)(+) progenitor cells derived from hPSCs.
Our findings have important potential clinical implications, indicating that EPO supplementation in rhabdomyosarcoma patients may have the unwanted side effect of tumor progression.
Higher levels of endogenous erythropoietin are associated with incident heart failure in older adults.
Erythropoietin protects mouse renal tubular basement membrane by promoting bone marrow cells to generate and secrete miR (show MLXIP Proteins)-144, which, in turn, inhibits activation of the tPA (show PLAT Proteins)/MMP9 (show MMP9 Proteins)-mediated proteolytic network.
The review describes the induction of erythropoietin gene expression in liver, reproouctive and hemopoietic systems during hypoxia or a state of proliferation.
Our data suggest that rs507392 and rs551238 in the erythropoietin gene probably act to lessen the risk for diabetic retinopathy (DR) in a Chinese cohort with type 2 diabetes mellitus (T2DM).
Data suggest maternal circulating 25-hydroxyvitamin D during mid-pregnancy and at delivery is inversely related to serum EPO; an indirect relation observed between circulating vitamin D and circulating hemoglobin (show HBB Proteins) is at least partly mediated by EPO.
The addition of salt (even low concentrations of the strong chaotrope salt guanidinium hydrochloride) also exponentially decreased the initial rate of soluble erythropoietin non-native aggregation at 37 degrees C storage
genetic analysis suggests that tubulointerstitial cellular crosstalk modulates renal EPO production under conditions of epithelial HIF activation in the kidney.
DNA methyltransferase (show DNMT1 Proteins) inhibition restores erythropoietin production in fibrotic murine kidneys
Midazolam suppresses hypoxia-induced up-regulation of EPO in brain.
erythropoietin activates AKT (show AKT1 Proteins), which phosphorylates GATA-1 (show GATA1 Proteins) at Ser310, thereby increasing GATA-1 (show GATA1 Proteins) affinity for FOG-1 (show ZFPM1 Proteins)
a novel RIPC mechanism in which inhibition of infarct size by RIPC is produced through the renal nerve-mediated reduction of RBF (show ATP5I Proteins) associated with activation of the HIF1alpha (show HIF1A Proteins)-EPO pathway.
Our data suggest that EPO-alpha and EPO-Z are not biosimilars for the wound healing effects. The higher efficacy of EPO-alpha might be likely due to its different conformational structure leading to a more efficient cell proliferation and skin remodelling.
this study proposes a chemically regulated system of erythropoiesis that can be used as part of a peroral therapeutic strategy to treat Epo-deficiency anemia and provides us with the molecular mechanisms explaining the activation of the Epo-EpoR (show EPOR Proteins) system
Report cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin.
EPO enhances chondrogenic and angiogenic responses during bone repair.
findings are that chronic central Epo overexpression stimulates central breathing activity during hypoxia at early post-natal ages; results also suggest that erythropoietin accelerates the maturation of the newborn respiratory network and its response to hypoxia
EPO might play a role as a survival factor or as a mitogen in developing cartilage tissue.
Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass.
A single intramuscular injection of recombinant adeno (show ADORA2A Proteins)-associated virus carrying mutant Epo (R76E) preserves retinal ganglion cells and visual function in glaucomatous mice.
The zebrafish epo cDNA was cloned and the expression of zepo mRNA was mainly in the heart and liver.
characterization of zebrafish epo and epor (show EPOR Proteins) demonstrates the conservation of an ancient program that ensures proper red blood cell numbers during normal homeostasis and under hypoxic conditions
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.