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Browse our IL7 Proteins (IL7)

Full name:
Interleukin 7 Proteins (IL7)
On are 105 Interleukin 7 (IL7) Proteins from 21 different suppliers available. Additionally we are shipping IL7 Antibodies (251) and IL7 Kits (89) and many more products for this protein. A total of 450 IL7 products are currently listed.
A630026I06Rik, hlb368, Il-7, IL7
list all proteins Gene Name GeneID UniProt
IL7 3574 P13232
IL7 16196 P10168
IL7 25647  

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IL7 Proteins (IL7) by Origin

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Top referenced IL7 Proteins

  1. Human IL7 Protein expressed in Escherichia coli (E. coli) - ABIN2667542 : Guimond, Veenstra, Grindler, Zhang, Cui, Murphy, Kim, Na, Hennighausen, Kurtulus, Erman, Matzinger, Merchant, Mackall: Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. in Nature immunology 2009 (PubMed)
    Show all 8 references for ABIN2667542

  2. Human IL7 Protein expressed in HEK-293 - ABIN2666668 : Lai, Zeff, Goldschneider: A recombinant single-chain IL-7/HGFbeta hybrid cytokine induces juxtacrine interactions of the IL-7 and HGF (c-Met) receptors and stimulates the proliferation of CFU-S12, CLPs, and pre-pro-B cells. in Blood 2006 (PubMed)
    Show all 8 references for ABIN2666668

  3. Mouse (Murine) IL7 Protein expressed in Insect Cells - ABIN2666591 : Li, Guszczynski, Hixon, Durum: Interleukin-7 regulates Bim proapoptotic activity in peripheral T-cell survival. in Molecular and cellular biology 2010 (PubMed)
    Show all 6 references for ABIN2666591

  4. Human IL7 Protein expressed in Escherichia coli (E. coli) - ABIN1305105 : Goodwin, Lupton, Schmierer, Hjerrild, Jerzy, Clevenger, Gillis, Cosman, Namen: Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 3 references for ABIN1305105

  5. Human IL7 Protein expressed in Escherichia coli (E. coli) - ABIN1888605 : Staron, Yang, Liu, Li, Shen, Zúñiga-Pflücker, Aguila, Goldschneider, Li: gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis. in Blood 2010 (PubMed)

  6. Human IL7 Protein expressed in HEK-293 Cells - ABIN2181324 : Parkinson, Graham, Daubersies, Burns, Heufler, Plumb, Schuler, Pragnell: Hemopoietic stem cell inhibitor (SCI/MIP-1 alpha) also inhibits clonogenic epidermal keratinocyte proliferation. in The Journal of investigative dermatology 1993 (PubMed)

  7. Mouse (Murine) IL7 Protein expressed in Escherichia coli (E. coli) - ABIN1888631 : Chari, Winandy: Ikaros regulates Notch target gene expression in developing thymocytes. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Proteins for IL7 Interaction Partners

Rhesus Monkey Interleukin 7 (IL7) interaction partners

  1. increased IL-7 protein production in situ (lung tissue) from non-human primates who received rBCG vaccination, which was associated with increased survival.

Human Interleukin 7 (IL7) interaction partners

  1. review of role of IL-7 in immunity and its role in the pathogenesis of neoplasia [review]

  2. Indian patients with primary Sjogren's syndrome have higher salivary sL-selectin and IL-7 levels than healthy controls

  3. increased IL-7 was secreted by mesenchymal stem cells (MSC (show MSC Proteins)) in the bone marrow, which may protect leukemic cells from apoptosis induced by imatinib through JAK1 (show JAK1 Proteins)/STAT5 (show STAT5A Proteins) signaling pathway

  4. The results from this study suggested for the first time that miR (show MLXIP Proteins)-181c was able to negatively regulate the production of proinflammatory cytokines IL-7 and IL-17 (show IL17A Proteins) in myasthenia gravis patients.

  5. Increase in serum IL-7 is associated with adenoma.

  6. provides negative feedback on its own signaling in T cells via endocytosis and degradation of its receptor, CD127 (show IL7R Proteins)

  7. Observed highly significant reductions in the concentration of circulating interleukin (IL)-16 (show IL16 Proteins), IL-7, and Vascular Endothelial Growth Factor A (VEGF-A (show VEGFA Proteins)) in encephalomyelitis/chronic fatigue syndrome patients.

  8. The observations suggest that IL-7 may play a role in the pathogenesis of Graves' disease and may be associated with its clinical activity.

  9. IL-7 and SCF (show KITLG Proteins) are elevated for a prolonged period after double umbilical cord blood transplantation and persistently high levels of these cytokines may correlate with worse clinical outcomes.

  10. Common gamma-chain (show IL2RG Proteins) cytokines IL-2 (show IL2 Proteins), IL-7, and IL-15 (show IL15 Proteins) prevent differentiation of naive T cells in vitro and limit activation of primed T cells in the absence of antigenic stimulus, which can contribute to the formation of cytokine imbalance.

Mouse (Murine) Interleukin 7 (IL7) interaction partners

  1. findings support a redundant role for adaptive Th17 cell- and innate gammadeltaT17 cell-derived IL17 (show IL17A Proteins) in bacteria-induced colon carcinogenesis, stressing the importance of therapeutically targeting the cytokine itself rather than its cellular sources

  2. functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.

  3. continuous IL7 signaling was not required for tumor regression, although LIP of naive CD8 (show CD8A Proteins)+ T cells is usually regulated by IL7

  4. IL7 represses the follicular helper T cell gene program.

  5. This study uncovers the metabolic mechanisms by which IL-7 tailors the metabolism of memory T cells to promote their longevity and fast response to rechallenge.

  6. IL-7 reduced IRAK-M (show IRAK3 Proteins) expression and attenuated immune tolerance induced by either LPS (show TLR4 Proteins) or CpGA

  7. Poly I:C induces IL-7 production, early inflammatory responses, and characteristic pathologies of SS-like dacryoadenitis in non-autoimmune-prone C57BL/6 mice.

  8. Data show that interleukin 7 (IL-7) signaling is a prerequisite for optimal CD4 (show CD4 Proteins)(+) T cell activation.

  9. reduced surface expression of IL-7R and concomitant limited responsiveness to IL-7 signals as a common mechanism resulting in reduced cell survival of common lymphoid progenitors and thymocytes at the double-negative to double-positive transition

  10. Hair follicle expression of IL-7 was required for CD8 (show CD8A Proteins)+ and CD4 (show CD4 Proteins)+ skin-resident memory T (TRM) cells to exert tropism for the epidermis. In a cutaneous T cell lymphoma model, CD4 (show CD4 Proteins)+ TRM lymphoma cell localization depended on hair follicle-derived IL-7.

IL7 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Alternative names and synonyms associated with IL7

  • interleukin 7 (IL7)
  • interleukin 7 (Il7)
  • interleukin 7-like (LOC100345409)
  • A630026I06Rik protein
  • hlb368 protein
  • Il-7 protein
  • IL7 protein

Protein level used designations for Interleukin 7 Proteins (IL7)

interleukin 7 , interleukin-7 , IL-7

464245 Pan troglodytes
574168 Macaca mulatta
3574 Homo sapiens
16196 Mus musculus
25647 Rattus norvegicus
100725811 Cavia porcellus
397253 Sus scrofa
280827 Bos taurus
443341 Ovis aries
751768 Canis lupus familiaris
420193 Gallus gallus
100345409 Oryctolagus cuniculus
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