Browse our IL7 Proteins (IL7)

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Interleukin 7 Proteins (IL7)
On are 109 Interleukin 7 (IL7) Proteins from 23 different suppliers available. Additionally we are shipping IL7 Antibodies (274) and IL7 Kits (94) and many more products for this protein. A total of 484 IL7 products are currently listed.
A630026I06Rik, hlb368, Il-7, IL7
list all proteins Gene Name GeneID UniProt
IL7 3574 P13232
IL7 16196 P10168
IL7 25647  

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IL7 Proteins (IL7) by Origin

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Top referenced IL7 Proteins

  1. Human IL7 Protein expressed in HEK-293 - ABIN2666668 : Guimond, Veenstra, Grindler, Zhang, Cui, Murphy, Kim, Na, Hennighausen, Kurtulus, Erman, Matzinger, Merchant, Mackall: Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. in Nature immunology 2009 (PubMed)
    Show all 8 references for 2666668

  2. Mouse (Murine) IL7 Protein expressed in Insect Cells - ABIN2666591 : Li, Guszczynski, Hixon, Durum: Interleukin-7 regulates Bim proapoptotic activity in peripheral T-cell survival. in Molecular and cellular biology 2010 (PubMed)
    Show all 6 references for 2666591

  3. Human IL7 Protein expressed in Escherichia coli (E. coli) - ABIN1305105 : Goodwin, Lupton, Schmierer, Hjerrild, Jerzy, Clevenger, Gillis, Cosman, Namen: Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 3 references for 1305105

  4. Human IL7 Protein expressed in Escherichia coli (E. coli) - ABIN1888605 : Staron, Yang, Liu, Li, Shen, Zúñiga-Pflücker, Aguila, Goldschneider, Li: gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis. in Blood 2010 (PubMed)

  5. Human IL7 Protein expressed in HEK-293 Cells - ABIN2181324 : Parkinson, Graham, Daubersies, Burns, Heufler, Plumb, Schuler, Pragnell: Hemopoietic stem cell inhibitor (SCI/MIP-1 alpha) also inhibits clonogenic epidermal keratinocyte proliferation. in The Journal of investigative dermatology 1993 (PubMed)

  6. Mouse (Murine) IL7 Protein expressed in Escherichia coli (E. coli) - ABIN1888631 : Chari, Winandy: Ikaros regulates Notch target gene expression in developing thymocytes. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Proteins for IL7 Interaction Partners

Rhesus Monkey Interleukin 7 (IL7) interaction partners

  1. increased IL-7 protein production in situ (lung tissue) from non-human primates who received rBCG vaccination, which was associated with increased survival.

Human Interleukin 7 (IL7) interaction partners

  1. this study shows that IL-7 restores T Lymphocyte immunometabolic failure in septic shock patients through mTOR (show FRAP1 Proteins) activation

  2. In CRC (show CALR Proteins), IL-7 was higher in patients with lymph node and distant metastases and with tumors located in right colon. In adenomas, IL-7 elevation was associated exclusively with villous growth pattern, while in IBD, circulating IL-7 reflected clinical activity of Crohn's disease and ulcerative colitis.

  3. Tuberculosis patients had lower soluble IL-7R and higher IL-7 plasma concentrations as compared to healthy contacts.

  4. CD56 (show NCAM1 Proteins)(bright) NK IL-7Ralpha (show IL7R Proteins) expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections

  5. IL-7 has a role inducing epitope masking of gammac protein in IL-7 receptor signaling complex

  6. Therefore, generalized CD8 (show CD8A Proteins)+ T-cell impairment in HCV infection is characterized, in part, by impaired IL-7-mediated signalling and survival, independent of CD127 (show IL7R Proteins) expression. This impairment is more pronounced in the liver and may be associated with an increased potential for apoptosis. This generalized CD8 (show CD8A Proteins)+ T-cell impairment represents an important immune dysfunction in chronic HCV infection that may alter patient health.

  7. These results reveal a novel role of IL-7 and IL-15 (show IL15 Proteins) in maintaining human T cell function, provide an explanation for T cell dysfunction in humanized mice, and have significant implications for in vitro studies with human T cells.

  8. The results show that SNPs in IL7 caused a significant association in this OA Chinese Han population.

  9. IL-7 is capable of enhancing functional T cell activity without causing significant functional inbalance between various T cell subsets.

  10. A compensatory mechanism of IL-7-mediated homeostatic proliferation can restore the inhibitory network of CD24 (show CD24 Proteins)+Foxp3 (show FOXP3 Proteins)+Treg cell after anti-CD25 (show IL2RA Proteins) induction therapy in islet allotransplantation.

Mouse (Murine) Interleukin 7 (IL7) interaction partners

  1. this study shows that IL-7 homeostasis is achieved through consumption by multiple subsets of innate and adaptive immune cells

  2. lymphatic vessel expansion occurs in two distinct phases; the first wave of expansion is dependent on IL-7; the second phase, responsible for leukocyte exit from the glands, is regulated by lymphotoxin (show LTB Proteins) (LT)betaR signaling

  3. DNM2 (show DNM2 Proteins) mutations cooperate with Lmo2 (show LMO2 Proteins) T-cell oncogenes by enhancing IL-7 signalling.

  4. IL-7 responsiveness in RTE is designed to maximize survival at the expense of reduced proliferation, consistent with RTE serving as a subpopulation of T cells rich in diversity but not in frequency.

  5. Expression of IL-7 is beneficial for induction of potent and long-lasting humoral immune responses.

  6. findings support a redundant role for adaptive Th17 cell- and innate gammadeltaT17 cell-derived IL17 (show IL17A Proteins) in bacteria-induced colon carcinogenesis, stressing the importance of therapeutically targeting the cytokine itself rather than its cellular sources

  7. functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.

  8. continuous IL7 signaling was not required for tumor regression, although LIP of naive CD8 (show CD8A Proteins)+ T cells is usually regulated by IL7

  9. IL7 represses the follicular helper T cell gene program.

  10. This study uncovers the metabolic mechanisms by which IL-7 tailors the metabolism of memory T cells to promote their longevity and fast response to rechallenge.

IL7 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Alternative names and synonyms associated with IL7

  • interleukin 7 (IL7)
  • interleukin 7 (Il7)
  • interleukin 7-like (LOC100345409)
  • A630026I06Rik protein
  • hlb368 protein
  • Il-7 protein
  • IL7 protein

Protein level used designations for Interleukin 7 Proteins (IL7)

interleukin 7 , interleukin-7 , IL-7

464245 Pan troglodytes
574168 Macaca mulatta
3574 Homo sapiens
16196 Mus musculus
25647 Rattus norvegicus
100725811 Cavia porcellus
397253 Sus scrofa
280827 Bos taurus
443341 Ovis aries
751768 Canis lupus familiaris
420193 Gallus gallus
100345409 Oryctolagus cuniculus
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