IL-7 Protein (AA 26-154) (His tag)
Quick Overview for IL-7 Protein (AA 26-154) (His tag) (ABIN2018155)
Target
See all IL-7 (IL7) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 26-154
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Purification tag / Conjugate
- This IL-7 protein is labelled with His tag.
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Characteristics
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ED50<0.4 ng/mL, measured in a cell proliferation assay using 2E8 cells.
AA 26-154, expressed with C-terminal 6×His. -
Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant murine Interleukin-7 (IL-7), His remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, murine Interleukin-7 (IL-7), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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Expiry Date
- 6 months
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- IL-7 (IL7) (Interleukin 7 (IL7))
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Alternative Name
- Interleukin-7 (IL-7)
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Background
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Interleukin-7 (IL-7), also known as lymphopoietin 1 and pre-B cell factor, is a hematopoietic growth factor belonging to the IL-7/IL-9 family. It is produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. IL-7 binds and signals through IL-7 receptor,a heterodimer consisting of IL-7 receptor alpha and common gamma chain receptor.IL-7 plays a role in regulating early B cell and T cell development. It is also important for optimal dendritic cell-T cell interaction.
Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor -
Molecular Weight
- 8-28 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q544C8
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Pathways
- JAK-STAT Signaling
Target
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