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Browse our anti-JAK2 (JAK2) Antibodies

Full name:
anti-Janus Kinase 2 Antibodies (JAK2)
On www.antibodies-online.com are 257 Janus Kinase 2 (JAK2) Antibodies from 26 different suppliers available. Additionally we are shipping JAK2 Kits (26) and JAK2 Proteins (21) and many more products for this protein. A total of 317 JAK2 products are currently listed.
Synonyms:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Most Popular Reactivities for anti-JAK2 (JAK2) Antibodies

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anti-Human JAK2 Antibodies:

anti-Mouse (Murine) JAK2 Antibodies:

anti-Rat (Rattus) JAK2 Antibodies:

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Top referenced anti-JAK2 Antibodies

  1. Human Polyclonal JAK2 Primary Antibody for FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 5 references for ABIN387982

  2. Human Monoclonal JAK2 Primary Antibody for ELISA, WB - ABIN969223 : Pezet, Buteau, Kelly, Edery: The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor. in Molecular and cellular endocrinology 1997 (PubMed)
    Show all 3 references for ABIN969223

  3. Human Polyclonal JAK2 Primary Antibody for IF, ELISA - ABIN1532352 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Show all 2 references for ABIN1532352

  4. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1532914 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Show all 2 references for ABIN1532914

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody for IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 2 references for ABIN658412

  6. Human Polyclonal JAK2 Primary Antibody for EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

More Antibodies against JAK2 Interaction Partners

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (show IFNG Antibodies) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. Alterated IQGAP1 (show IQGAP1 Antibodies)/Rho GTPase (show RACGAP1 Antibodies) signaling in myeloproliferative neoplasm erythrocytes is dependent on JAK2/CALR (show CALR Antibodies) mutational status.

  2. primary cells from a patient with KRAS-mutant juvenile myelomonocytic leukemia displayed reduced colony formation in response to JAK2 inhibition

  3. The results showed that AG490 inhibited (p)-JAK2 and RANKL (show TNFSF11 Antibodies) expression.

  4. the accumulation of reactive oxygen species (ROS (show ROS1 Antibodies)) in cells expressing JAK2V617F compromises the NHE-1 (show SLC9A1 Antibodies)/Bcl-xL (show BCL2L1 Antibodies) deamidation pathway by repressing NHE-1 (show SLC9A1 Antibodies) upregulation in response to DNA damage. hematopoietic stem cells (HSCs), FOXO3A (show FOXO3 Antibodies) is largely localized within the nuclei despite the presence of JAK2V617F mutation, suggesting that JAK2-FOXO (show FOXO3 Antibodies) signaling has a different effect on progenitors compared with stem cells.

  5. Overexpression of Msi2 (show MSI2 Antibodies) significantly increased and silencing of Msi2 (show MSI2 Antibodies) reduced the phosphorylation of JAK2 and its downstream effecter STAT3 (show STAT3 Antibodies).

  6. our data elucidate that knockdown of HOXD-AS1 (show PTGDR Antibodies) dramatically suppresses gastric cancer cell growth by inactivating the Janus kinase 2/signal transducer and activator of transcription 3 (show STAT3 Antibodies) pathway in vitro and in vivo, contributing to a better understanding of gastric cancer pathogenesis and providing a possible theoretical foundation for long non-coding RNA-directed diagnosis and therapy against this disease.

  7. Germline variation in the JAK2 gene was associated with survival in patients with castration-resistant prostate cancer

  8. TERT (show TERT Antibodies) rs2736100 A>C SNP and JAK2 46/1 haplotype significantly contribute to the occurrence of JAK2 V617F and CALR (show CALR Antibodies) mutated myeloproliferative neoplasms

  9. this study shows that Korean patients with psoriasis show a strong association for JAK2 single nucleotide polymorphism

  10. JAK2 is a direct BCL6 (show BCL6 Antibodies) target gene; BCL6 (show BCL6 Antibodies) bound to the JAK2 promoter

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. Data show that CUZD1 (show CUZD1 Antibodies) interacts with a complex containing JAK1 (show JAK1 Antibodies)/JAK2 and STAT5 (show STAT5A Antibodies), downstream transducers of prolactin (show PRL Antibodies) signaling in the mammary gland.

  2. The results showed that AG490 inhibited (p)-JAK2 and RANKL (show TNFSF11 Antibodies) expression.

  3. these results have revealed that phosphorylation of Tyr (show TYR Antibodies)-343, Tyr (show TYR Antibodies)-460, and Tyr (show TYR Antibodies)-464 in EpoR (show EPOR Antibodies) underlies JAK2 V617F mutant-induced tumorigenesis.

  4. this study shows that ampelopsin reduces inflammatory response of microglial cells through inhibition of JAK2-STAT3 (show STAT3 Antibodies) signaling

  5. At the molecular level, administration of liraglutide induced the expression of PDX-1 (show PDX1 Antibodies), MafA (show MAFA Antibodies), p-JAK2 and p-Stat3 (show STAT3 Antibodies) in high-fat diet-induced diabetes model to relatively normal levels.

  6. this study shows that resokaempferol inhibits the inflammatory response in activated macrophages by blocking the activation of the JAK2 pathway

  7. Data show that protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Antibodies))-deficiency enhanced JAK2-STAT3 (show STAT3 Antibodies) signaling in hypothalamic microglia and attenuated inflammation.

  8. JAK1 (show JAK1 Antibodies), JAK2, and JAK3 (show JAK3 Antibodies) are involved in stimulation of functional activity of mesenchymal progenitor cells by fibroblast growth factor.

  9. JAK (show JAK3 Antibodies) mediated signaling is involved in the differentiation and proliferation of mesenchymal progenitor cells.

  10. IL-3 (show IL-3 Antibodies) signaling does not contribute to Jak2 V617F myeloproliferative neoplasm pathogenesis.

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies)-AKT (show AKT1 Antibodies) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (show STAT5A Antibodies) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (show STAT5A Antibodies) and mTOR (show FRAP1 Antibodies) signaling pathways.

  4. SNPs in JAK2 and STAT5B (show STAT5B Antibodies) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 Antigen Profile

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) antibody
  • Janus kinase 2 (JAK2) antibody
  • Janus kinase 2 (Jak2) antibody
  • tyrosine-protein kinase JAK2-like (LOC100051487) antibody
  • AI504024 antibody
  • C81284 antibody
  • Fd17 antibody
  • JAK-2 antibody
  • jak2 antibody
  • JAK2bCA antibody
  • JTK10 antibody
  • THCYT3 antibody

Protein level used designations for anti-Janus Kinase 2 (JAK2) Antibodies

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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