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Browse our anti-JAK2 (JAK2) Antibodies

Full name:
anti-Janus Kinase 2 Antibodies (JAK2)
On www.antibodies-online.com are 245 Janus Kinase 2 (JAK2) Antibodies from 25 different suppliers available. Additionally we are shipping JAK2 Kits (23) and JAK2 Proteins (18) and many more products for this protein. A total of 299 JAK2 products are currently listed.
Synonyms:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

All available anti-JAK2 Antibodies

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Top referenced anti-JAK2 Antibodies

  1. Human Polyclonal JAK2 Primary Antibody for FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 5 references for ABIN387982

  2. Human Monoclonal JAK2 Primary Antibody for ELISA, WB - ABIN969223 : Pezet, Buteau, Kelly, Edery: The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor. in Molecular and cellular endocrinology 1997 (PubMed)
    Show all 3 references for ABIN969223

  3. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1532913 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Show all 2 references for ABIN1532913

  4. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1533083 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Show all 2 references for ABIN1533083

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody for IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 2 references for ABIN658412

  6. Human Polyclonal JAK2 Primary Antibody for EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

More Antibodies against JAK2 Interaction Partners

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (show IFNG Antibodies) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. we demonstrate that like other kinases JAK2 is prone to develop resistant mutations against ATP site inhibitors, but targeting the substrate-binding site prevents the selection of resistant mutations.

  2. by molecular docking analysis and tumor sphere assay we discover that curcumin was able to inhibit JAK2 activity and reduce tumor spheres via inhibiting the JAK2/STAT3 (show STAT3 Antibodies) signaling pathway

  3. we conclude that the JAK2-STAT3 (show STAT3 Antibodies) pathway promotes the development of paclitaxel resistance via upregulating the expression of prosurvival and antiapoptotic genes.

  4. Our results reveal JAK2 as critical component of chemokine (show CCL1 Antibodies) signaling in B-cell chronic lymphocytic leukemia B-lymphocytes

  5. Data suggest that stathmin 1 (show STMN1 Antibodies) silencing or paclitaxel treatment, combined with ruxolitinib could be an effective strategy for promoting apoptosis in Janus kinase 2 (JAK2 V617F) cells.

  6. Genomic amplification of 9p24.1 targeting JAK2, PD-L1 (show CD274 Antibodies), and PD-L2 (show PDCD1LG2 Antibodies) is enriched in high-risk triple negative breast cancer.

  7. Janus Kinase 2/Signal Transducer and Activator of Transcription 3 (show STAT3 Antibodies) (JAK2/STAT3 (show STAT3 Antibodies)) inhibitor AG490 significantly inhibited the migration, invasion and MMP-2 (show MMP2 Antibodies) expression induced by leptin (show LEP Antibodies) in endometriotic cells.

  8. a novel role for JAK2/STAT1 (show STAT1 Antibodies) in EGFR (show EGFR Antibodies)-mediated immune evasion, and therapies targeting this signaling axis may be beneficial to block PD-L1 (show CD274 Antibodies) upregulation found in a large subset of head and neck cancer tumors.

  9. study provided evidence that the presence of the JAK2V617F mutation is associated with quantitative changes in monocyte and lymphocyte populations, namely marked reduction in the percentage of monocytes, CD8 (show CD8A Antibodies)+ T and B cells and concurrent increase in NK cells

  10. Suggest JAK2/STAT1 (show STAT1 Antibodies) signaling has key role in transducing endothelial transcriptomic changes induced by oxLDL.

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. The critical role of Jak2 in mediating prolactin (show PRL Antibodies)-induced luminal maturation of mammary epithelial cells.

  2. JAK1 (show JAK1 Antibodies)/JAK2 inhibition of graft-versus-host disease was associated with the modulation of chemokine receptor (show CCR1 Antibodies) expression, which may have been one factor in the reduced infiltration of donor T cells in graft-versus-host disease target organs.

  3. Findings indicate that CD24(+) antigen (show CD24 Antibodies) cells play a role in tumor migration and metastasis and support Janus kinase 2 protein (JAK2) as a therapeutic target in ovarian cancer.

  4. JAK2(V617I) resulted in cytokine hyperresponsiveness without constitutive activation in the absence of ligand, whereas JAK2(V617F) resulted in constitutive activation

  5. The pro-inflammatory cytokine, interferon-gamma (show IFNG Antibodies) may contribute to diarrhea associated with intestinal inflammation in part through regulation of the epithelial aquaporin-1 (show AQP1 Antibodies) water channel (show AQP4 Antibodies) via a non-classical JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) receptor signalling pathway.

  6. JAK2 participates in the signalling, regulating the voltage-gated K(+) channel (show KCND3 Antibodies) KCNA3 (show KCNA3 Antibodies).

  7. PRDX6 (show PRDX6 Antibodies) promotes lung tumor development via its mediated and CCL5 (show CCL5 Antibodies)-associated activation of the JAK2/STAT3 (show STAT3 Antibodies) pathway.

  8. The data support an important role of LIF (show LIF Antibodies)-JAK2-STAT3 (show STAT3 Antibodies) regulation in the development of colonic adenocarcinoma-related cachexia.

  9. Studied the liver-specific role of PTP1B (show PTPN1 Antibodies) in GH signaling; found under 48-hour fasting GH-resistant conditions, GH stimulation in vivo led to a robust stimulation of the JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies) signalling pathway.

  10. HDAC2 (show HDAC2 Antibodies) might be a downstream effector of Jak2 to mediate cardiac hypertrophic response by pressure overload or Ang-II (show AGT Antibodies).

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies)-AKT (show AKT1 Antibodies) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (show STAT5A Antibodies) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (show STAT5A Antibodies) and mTOR (show FRAP1 Antibodies) signaling pathways.

  4. SNPs in JAK2 and STAT5B (show STAT5B Antibodies) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 Antigen Profile

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) antibody
  • Janus kinase 2 (JAK2) antibody
  • Janus kinase 2 (Jak2) antibody
  • tyrosine-protein kinase JAK2-like (LOC100051487) antibody
  • AI504024 antibody
  • C81284 antibody
  • Fd17 antibody
  • JAK-2 antibody
  • jak2 antibody
  • JAK2bCA antibody
  • JTK10 antibody
  • THCYT3 antibody

Protein level used designations for anti-Janus Kinase 2 (JAK2) Antibodies

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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