Browse our anti-JAK2 (JAK2) Antibodies

Full name:
anti-Janus Kinase 2 Antibodies (JAK2)
On www.antibodies-online.com are 280 Janus Kinase 2 (JAK2) Antibodies from 29 different suppliers available. Additionally we are shipping JAK2 Kits (30) and JAK2 Proteins (25) and many more products for this protein. A total of 349 JAK2 products are currently listed.
Synonyms:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Most Popular Reactivities for anti-JAK2 (JAK2) Antibodies

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anti-Human JAK2 Antibodies:

anti-Mouse (Murine) JAK2 Antibodies:

anti-Rat (Rattus) JAK2 Antibodies:

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Top referenced anti-JAK2 Antibodies

  1. Human Polyclonal JAK2 Primary Antibody for WB - ABIN265197 : Manning, DiSalvo, Stull: Protein phosphorylation: quantitative analysis in vivo and in intact cell systems. in Molecular and cellular endocrinology 1980 (PubMed)
    Show all 12 references for 265197

  2. Human Polyclonal JAK2 Primary Antibody for FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 5 references for 387982

  3. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1532914 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Show all 2 references for 1532914

  4. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1533083 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Show all 2 references for 1533083

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody for IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 2 references for 658412

  6. Human Polyclonal JAK2 Primary Antibody for EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

More Antibodies against JAK2 Interaction Partners

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (show IFNG Antibodies) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. Molecular interactions of EphA4 (show EPHA4 Antibodies), growth hormone receptor (show GHR Antibodies), Jak2, and STAT5B (show STAT5B Antibodies) have been described.

  2. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 (show IL6 Antibodies) promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 (show STAT3 Antibodies) signaling pathway.

  3. Mutation inactivating JAK2 gene is associated with Breast Cancer Metastasis.

  4. mechanical load upregulates expression of Runx2 (show RUNX2 Antibodies) gene via potentiation of PC1 (show PCSK1 Antibodies)-JAK2/STAT3 (show STAT3 Antibodies) signaling axis, culminating to possibly control osteoblastic differentiation and ultimately bone formation.

  5. blocking the ERRalpha (show ESRRA Antibodies)-controlled mitochondrial program largely inhibits the PLA2R1 (show PLA2R1 Antibodies)-induced tumor-suppressive response. Together, our data document ERRalpha (show ESRRA Antibodies) and its mitochondrial program as downstream effectors of the PLA2R1 (show PLA2R1 Antibodies)-JAK2 pathway leading to oncosuppression.

  6. JAK2 was overexpressed in Epstein Barr virus-associated gastric adenocarcinoma.

  7. As marrow histology in this murine model of myeloproliferation reveals a preferentially perivascular localization of JAK2(V617F)-mutant megakaryocytes and an increased marrow sinusoid vascular density

  8. mutated FLT3 (show FLT3 Antibodies)-ITD and JAK2 augment reactive oxygen species production and homologous recombination, shifting the cellular milieu toward illegitimate recombination events.

  9. Germ line JAK2 mutations E846D and R1063H are associated with hereditary erythrocytosis with megakaryocytic atypia.

  10. Data suggest that ruxolitinib treatment for up to 4 years provides progressive reductions in Janus kinase 2 (JAK2) p.V617F allele burden in patients with polycythemia vera (show IGF2BP3 Antibodies) (PV).

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. Study shows that Jak2 with V617F mutation induces murine model for myeloproliferative neoplasm.

  2. results suggest that loss of Ezh2 (show EZH2 Antibodies) cooperates with Jak2V617F in the development of myelofibrosis in Jak2V617F

  3. JAK2-V617F-expressing mice treated with an Ezh2 (show EZH2 Antibodies) inhibitor showed higher platelet counts than vehicle controls. Our data support the proposed tumor suppressor function of EZH2 (show EZH2 Antibodies)

  4. findings demonstrate that clinically relevant doses of the JAK1 (show JAK1 Antibodies)/2 inhibitor ruxolitinib suppresses the harmful consequences of macrophage overactivation characterizing Hemophagocytic lymphohistiocytosis in 2 murine models.

  5. JAK2 has a role in hepatocarcinogenesis through regulating critical inflammatory pathways

  6. Data show that CUZD1 (show CUZD1 Antibodies) interacts with a complex containing JAK1 (show JAK1 Antibodies)/JAK2 and STAT5 (show STAT5A Antibodies), downstream transducers of prolactin (show PRL Antibodies) signaling in the mammary gland.

  7. The results showed that AG490 inhibited (p)-JAK2 and RANKL (show TNFSF11 Antibodies) expression.

  8. these results have revealed that phosphorylation of Tyr (show TYR Antibodies)-343, Tyr (show TYR Antibodies)-460, and Tyr (show TYR Antibodies)-464 in EpoR (show EPOR Antibodies) underlies JAK2 V617F mutant-induced tumorigenesis.

  9. this study shows that ampelopsin reduces inflammatory response of microglial cells through inhibition of JAK2-STAT3 (show STAT3 Antibodies) signaling

  10. At the molecular level, administration of liraglutide induced the expression of PDX-1 (show PDX1 Antibodies), MafA (show MAFA Antibodies), p-JAK2 and p-Stat3 (show STAT3 Antibodies) in high-fat diet-induced diabetes model to relatively normal levels.

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies)-AKT (show AKT1 Antibodies) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (show STAT5A Antibodies) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (show STAT5A Antibodies) and mTOR (show FRAP1 Antibodies) signaling pathways.

  4. SNPs in JAK2 and STAT5B (show STAT5B Antibodies) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 Antigen Profile

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) antibody
  • Janus kinase 2 (JAK2) antibody
  • Janus kinase 2 (Jak2) antibody
  • tyrosine-protein kinase JAK2-like (LOC100051487) antibody
  • AI504024 antibody
  • C81284 antibody
  • Fd17 antibody
  • JAK-2 antibody
  • jak2 antibody
  • JAK2bCA antibody
  • JTK10 antibody
  • THCYT3 antibody

Protein level used designations for anti-Janus Kinase 2 (JAK2) Antibodies

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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