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Browse our anti-JAK2 (JAK2) Antibodies

Full name:
anti-Janus Kinase 2 Antibodies (JAK2)
On www.antibodies-online.com are 260 Janus Kinase 2 (JAK2) Antibodies from 26 different suppliers available. Additionally we are shipping JAK2 Kits (22) and JAK2 Proteins (18) and many more products for this protein. A total of 313 JAK2 products are currently listed.
Synonyms:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Most Popular Reactivities for anti-JAK2 (JAK2) Antibodies

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anti-Human JAK2 Antibodies:

anti-Mouse (Murine) JAK2 Antibodies:

anti-Rat (Rattus) JAK2 Antibodies:

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Top referenced anti-JAK2 Antibodies

  1. Human Polyclonal JAK2 Primary Antibody for FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 5 references for ABIN387982

  2. Human Monoclonal JAK2 Primary Antibody for ELISA, WB - ABIN969223 : Pezet, Buteau, Kelly, Edery: The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor. in Molecular and cellular endocrinology 1997 (PubMed)
    Show all 3 references for ABIN969223

  3. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1532913 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Show all 2 references for ABIN1532913

  4. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1533083 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Show all 2 references for ABIN1533083

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody for IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 2 references for ABIN658412

  6. Human Polyclonal JAK2 Primary Antibody for EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

More Antibodies against JAK2 Interaction Partners

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (show IFNG Antibodies) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. Studies indicate that a genetic classification of primary fibrosis (PMF) by calreticulin (CALR (show CALR Antibodies)) and JAK2V617F (JAK2)mutations carried significant prognostic relevance.

  2. study investigated the presence of JAK2 (V617F) mutation in Egyptian patients with myeloproliferative disorders; results are concordant with international published results for detection of this mutation; JAK2 mutation may be also present in disorders other than MPDs (show DPM1 Antibodies) such as; different hypercoagulable states

  3. A heterozygous intronic JAK2 variant was found in familial cases diagnosed with gastric lymphoma and Hodgkin lymphoma.

  4. Case Report: refractory arterial insufficiency associated with JAK2-positive essential thrombocythaemia.

  5. Correlation analysis between JAK2 V617F allele burden and other parameters in patients with Philadelphia negative myeloproliferative neoplasms revealed statistical significant correlation with age, HB, HCT, PLT, UA, LDH, and splenic diameter but insignificant correlation with WBCs and PAH.

  6. A positive correlation of JAK2 V617F mutation was established.

  7. JAK2V617F and CALR (show CALR Antibodies) positive patients might have a different phenotype.

  8. Mutation status of JAK2, CALR (show CALR Antibodies), and MPL (show MPL Antibodies) in essential thrombocythemia and primary myelofibrosis defines clinical outcome.

  9. Data show that the expressions of p-JAK2 protein and p-STAT3 (show STAT3 Antibodies) protein were down-regulated after treated with Interferon-beta (IFN-beta (show IFNB1 Antibodies)) combined with all-trans retinoic acid (ATRA) on HepG2 cells, especially the combination of IFN-beta (show IFNB1 Antibodies) and ATRA.

  10. JAK2 amplification is a potential biomarker for JAK2 dependence.

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. IL-3 (show Il3 Antibodies) signaling does not contribute to Jak2 V617F myeloproliferative neoplasm pathogenesis.

  2. Fos-zippered GHR (show GHR Antibodies) tails and Jak2, both purified from baculovirus-infected insect cells, interacted via box1 with a binding affinity of approximately 40nM.

  3. Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 (show STAT5A Antibodies) signaling in genetically engineered mice with pancreatic ductal carcinomas.

  4. JAK2 plays a critical role in brown adipose tissue function and adaptive thermogenesis

  5. The critical role of Jak2 in mediating prolactin (show PRL Antibodies)-induced luminal maturation of mammary epithelial cells.

  6. JAK1 (show JAK1 Antibodies)/JAK2 inhibition of graft-versus-host disease was associated with the modulation of chemokine receptor (show CCR1 Antibodies) expression, which may have been one factor in the reduced infiltration of donor T cells in graft-versus-host disease target organs.

  7. Findings indicate that CD24(+) antigen (show CD24 Antibodies) cells play a role in tumor migration and metastasis and support Janus kinase 2 protein (JAK2) as a therapeutic target in ovarian cancer.

  8. JAK2(V617I) resulted in cytokine hyperresponsiveness without constitutive activation in the absence of ligand, whereas JAK2(V617F) resulted in constitutive activation

  9. The pro-inflammatory cytokine, interferon-gamma (show IFNG Antibodies) may contribute to diarrhea associated with intestinal inflammation in part through regulation of the epithelial aquaporin-1 (show AQP1 Antibodies) water channel (show AQP4 Antibodies) via a non-classical JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) receptor signalling pathway.

  10. JAK2 participates in the signalling, regulating the voltage-gated K(+) channel (show KCND3 Antibodies) KCNA3 (show KCNA3 Antibodies).

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies)-AKT (show AKT1 Antibodies) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (show STAT5A Antibodies) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (show STAT5A Antibodies) and mTOR (show FRAP1 Antibodies) signaling pathways.

  4. SNPs in JAK2 and STAT5B (show STAT5B Antibodies) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 Antigen Profile

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) antibody
  • Janus kinase 2 (JAK2) antibody
  • Janus kinase 2 (Jak2) antibody
  • tyrosine-protein kinase JAK2-like (LOC100051487) antibody
  • AI504024 antibody
  • C81284 antibody
  • Fd17 antibody
  • JAK-2 antibody
  • jak2 antibody
  • JAK2bCA antibody
  • JTK10 antibody
  • THCYT3 antibody

Protein level used designations for anti-Janus Kinase 2 (JAK2) Antibodies

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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