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Browse our anti-JAK2 (JAK2) Antibodies

Full name:
anti-Janus Kinase 2 Antibodies (JAK2)
On www.antibodies-online.com are 273 Janus Kinase 2 (JAK2) Antibodies from 27 different suppliers available. Additionally we are shipping JAK2 Kits (25) and JAK2 Proteins (21) and many more products for this protein. A total of 332 JAK2 products are currently listed.
Synonyms:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Most Popular Reactivities for anti-JAK2 (JAK2) Antibodies

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anti-Human JAK2 Antibodies:

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anti-Rat (Rattus) JAK2 Antibodies:

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Top referenced anti-JAK2 Antibodies

  1. Human Polyclonal JAK2 Primary Antibody for FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 5 references for ABIN387982

  2. Human Monoclonal JAK2 Primary Antibody for ELISA, WB - ABIN969223 : Pezet, Buteau, Kelly, Edery: The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor. in Molecular and cellular endocrinology 1997 (PubMed)
    Show all 3 references for ABIN969223

  3. Human Polyclonal JAK2 Primary Antibody for IF, ELISA - ABIN1532352 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Show all 2 references for ABIN1532352

  4. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1532914 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Show all 2 references for ABIN1532914

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody for IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 2 references for ABIN658412

  6. Human Polyclonal JAK2 Primary Antibody for EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

More Antibodies against JAK2 Interaction Partners

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (show IFNG Antibodies) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. JAK2 is a direct BCL6 (show BCL6 Antibodies) target gene; BCL6 (show BCL6 Antibodies) bound to the JAK2 promoter

  2. a concentration of tissue factor pathway inhibitor (show TFPI Antibodies) was significantly lower in patients with essential thrombocythemia with JAK2 V617F mutation as compared with patients without the mutation

  3. Upregulation of JAK2 is associated with chemotherapy response in pancreatic cancer.

  4. Xinqin exerts the anti-allergic effect by modulating mast cell-mediated allergic responses by down-regulating JAK2/STAT5 (show STAT5A Antibodies) signaling pathway.

  5. Myeloproliferative neoplasms are strong risk factors for splanchnic vein thrombosis. European studies have identified the low prevalence of CALR (show CALR Antibodies) somatic mutations in JAK2. The first outside of Europe study, in Australia, confirms that CALR (show CALR Antibodies) mutations are rare in patients with splanchnic vein thrombosis.

  6. CALR (show CALR Antibodies)- and JAK2-mutated MPNs are broadly similar in terms of the quantity, frequency and spectrum of co-occurring mutations and therefore observed biological differences are likely to not be heavily influenced by the nature and quantity of co-mutated genes.

  7. The family with JAK2 G571S mutations reported here teaches us that 1 germline JAK2 mutation may hide a somatic CALR (show CALR Antibodies) mutation, and that, in this case, the phenotype (thrombocytosis) and disease (essential thrombocythemia [ET]) are likely due to the somatic CALR (show CALR Antibodies) mutation. This highlights the complexity of making the diagnosis of ET (vs. HT) in a familial context.

  8. Demonstration of ASXL1 (show ASXL1 Antibodies) mutation, a putative tumor suppressor gene, represents an important molecular abnormality in CML (show BCR Antibodies). Authors also showed that concomitant detection of BCR-ABL (show ABL1 Antibodies) and JAK2V617F mutations has a relatively high incidence in Iranian patients.

  9. This study demonstrated that several JAK2 SNPs confer susceptibility to PV and ET. Rs12342421 and rs10758677 were the SNPs most significantly associated with Polycythemia Vera (show IGF2BP3 Antibodies) and Essential Thrombocythemia.

  10. Differential expression of LGALS1 (show LGALS1 Antibodies) and/or LGALS3 (show LGALS3 Antibodies) in patients with myeloproliferative neoplasm (MPN (show PRSS27 Antibodies)) is linked with JAK2 V617F status mutation in these diseases and state of cell differentiation.

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. At the molecular level, administration of liraglutide induced the expression of PDX-1 (show PDX1 Antibodies), MafA (show MAFA Antibodies), p-JAK2 and p-Stat3 (show STAT3 Antibodies) in high-fat diet-induced diabetes model to relatively normal levels.

  2. this study shows that resokaempferol inhibits the inflammatory response in activated macrophages by blocking the activation of the JAK2 pathway

  3. Data show that protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Antibodies))-deficiency enhanced JAK2-STAT3 (show STAT3 Antibodies) signaling in hypothalamic microglia and attenuated inflammation.

  4. JAK1 (show JAK1 Antibodies), JAK2, and JAK3 (show JAK3 Antibodies) are involved in stimulation of functional activity of mesenchymal progenitor cells by fibroblast growth factor.

  5. JAK (show JAK3 Antibodies) mediated signaling is involved in the differentiation and proliferation of mesenchymal progenitor cells.

  6. IL-3 (show IL-3 Antibodies) signaling does not contribute to Jak2 V617F myeloproliferative neoplasm pathogenesis.

  7. Fos-zippered GHR (show GHR Antibodies) tails and Jak2, both purified from baculovirus-infected insect cells, interacted via box1 with a binding affinity of approximately 40nM.

  8. Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 (show STAT5A Antibodies) signaling in genetically engineered mice with pancreatic ductal carcinomas.

  9. JAK2 plays a critical role in brown adipose tissue function and adaptive thermogenesis

  10. The critical role of Jak2 in mediating prolactin (show PRL Antibodies)-induced luminal maturation of mammary epithelial cells.

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies)-AKT (show AKT1 Antibodies) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (show STAT5A Antibodies) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (show STAT5A Antibodies) and mTOR (show FRAP1 Antibodies) signaling pathways.

  4. SNPs in JAK2 and STAT5B (show STAT5B Antibodies) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 Antigen Profile

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) antibody
  • Janus kinase 2 (JAK2) antibody
  • Janus kinase 2 (Jak2) antibody
  • tyrosine-protein kinase JAK2-like (LOC100051487) antibody
  • AI504024 antibody
  • C81284 antibody
  • Fd17 antibody
  • JAK-2 antibody
  • jak2 antibody
  • JAK2bCA antibody
  • JTK10 antibody
  • THCYT3 antibody

Protein level used designations for anti-Janus Kinase 2 (JAK2) Antibodies

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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