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JAK1 Antibodies

(Janus Kinase 1 (JAK1))
Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs. [provided by RefSeq, Jul 2008].
anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody (ABIN6255762)

JAK1 Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (C-Term) antibody anti-Janus Kinase 1 (JAK1) (C-Term) antibody anti-Janus Kinase 1 (JAK1) (C-Term) antibody (ABIN2704932)

JAK1 Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Pig IC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (Ser639) antibody anti-Janus Kinase 1 (JAK1) (Ser639) antibody anti-Janus Kinase 1 (JAK1) (Ser639) antibody (ABIN3185253)

JAK1 Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

JAK1 Antibodies by Reactivity

Find JAK1 Antibodies for a variety of species such as anti-Human JAK1, anti-Mouse JAK1, anti-Rat JAK1. The species listed below are among those available. Click on a link to go to the corresponding products.

JAK1 Antibodies by Application

Find JAK1 Antibodies validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

JAK1 Antibodies by Host

Find JAK1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

JAK1 Antibodies by Binding Specificity

Find JAK1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

JAK1 Antibodies by Clonality

Find available monoclonal or polyclonal JAK1 Antibodies. Click on a link to go to the corresponding products.

JAK1 Antibodies by Clone

Find JAK1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

JAK1 Antibodies by Conjugate

Find JAK1 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular JAK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1859521
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN5518768
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1531881
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN1533664
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN197300
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3028773
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Rat
Application ICC, IF, IP, WB
Validations
  • (2)
Cat. No. ABIN4953264
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3028775
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3028774
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Human, Mouse, Pig, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN2704931
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (1)
Cat. No. ABIN362702
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN743333
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6242900
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242901
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN561569
Quantity 50 μL
Datasheet Datasheet

Latest Publications for our JAK1 Antibodies

Fukasawa, Yoshizaki, Ebata, Yoshizaki-Ogawa, Asano, Enomoto, Miyagawa, Kazoe, Mawatari, Kitamori, Sato: "Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model." in: eLife, Vol. 10, (2021) (PubMed).

Huang, Zhou, Li, Ming, Li, Wu, Chen, Zhao: "In vivo and in vitro effects of microRNA-221 on hepatocellular carcinoma development and progression through the JAK-STAT3 signaling pathway by targeting SOCS3." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 3500-3514, (2019) (PubMed).

Chen, Zhou, Liu, Huang, Liu, Kang, Chen, Guo, Zhu, Sun: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).

Tu, Yu, Zhang, Shi, Xu, Hu, Gan, He, Dong, Han, Huang, Pan, Zhang: "A novel fluorinated triazole derivative suppresses macrophage activation and alleviates experimental colitis via a Twist1-dependent pathway." in: Biochemical pharmacology, Vol. 155, pp. 275-287, (2018) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Bai, Wang, Han, Xie, Ji, Yin, Chen, Wang, Jiang, Qi, Jiang: "BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo." in: Molecular carcinogenesis, Vol. 56, Issue 3, pp. 1137-1149, (2017) (PubMed).

Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Yang, Shen, Xu, Yang, Tsai, Keng, Chen, Lee: "Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition." in: Scientific reports, Vol. 7, Issue 1, pp. 7958, (2017) (PubMed).

Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." in: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, (2016) (PubMed).

Liu, Huang, Zeng, Chen, Huang, Guo, Liu, Xu, Mo, Li: "Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).

Aliases for JAK1 Antibodies

Janus kinase 1 (JAK1) Antibodies
Janus kinase 1 (Jak1) Antibodies
Janus kinase 1 (jak1) Antibodies
tyrosine-protein kinase JAK1 (LOC100286690) Antibodies
AA960307 Antibodies
C130039L05Rik Antibodies
jak1 Antibodies
JAK1A Antibodies
JAK1B Antibodies
JTK3 Antibodies
wu:fb93e10 Antibodies
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