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JAK2 Products

(Janus Kinase 2 (JAK2))
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008].

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Featured JAK2 Categories

JAK2 Antibodies

High quality antibodies with extensive validation data.

JAK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

JAK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended JAK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438352
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (5)
Cat. No. ABIN740955
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (6)
Cat. No. ABIN5542629
Quantity 0.1 mg
Datasheet Datasheet

Recommended JAK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957232
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968076
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4993543
Quantity 96 tests
Datasheet Datasheet

Recommended JAK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570137
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570057
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570752
Quantity 5 μg
Datasheet Datasheet

Latest Publications for our JAK2 products

Wang, Tang, Xiao, Lee, Cheng, Niu, Oguz, Feng, Lee, Li, Yang, Chen, Lan, Wu, Yu: "Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer." in: Nature communications, Vol. 12, Issue 1, pp. 4441, (2021) (PubMed).

Ma, Chen, Chen, Wei, Xu, Yang, Wang, Meng, Ren, Xu: "Erythropoietin Rescues Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via the EPO-R/JAK2/STAT5/PI3K/Akt/GSK-3β Pathway." in: Molecular neurobiology, Vol. 55, Issue 4, pp. 3290-3299, (2019) (PubMed).

Lan, Su, Liu, Deng, Wang, Chen, Jules, Masau, Li, Wei: "Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway." in: Life sciences, Vol. 228, pp. 35-46, (2019) (PubMed).

Deng, Bu, Mo, Lv, Song, Xiao, Dan, Yang: "Huang Gan Formula Eliminates the Oxidative Stress Effects of Advanced Oxidation Protein Products on the Divergent Regulation of the Expression of AGEs Receptors via the JAK2/STAT3 Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4520916, (2018) (PubMed).

Chen, Zhou, Liu, Huang, Liu, Kang, Chen, Guo, Zhu, Sun: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).

Wu, Xu, Xu, Zheng, Chen, Jiao: "Study on the mechanism of JAK2/STAT3 signaling pathway-mediated inflammatory reaction after cerebral ischemia." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5007-5012, (2018) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Li, Ma, Jiang, Bai, Yan, Liu, Pan, Liu, Chen: "Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus." in: Scientific reports, Vol. 7, Issue 1, pp. 353, (2017) (PubMed).

Liao, Hu, Guo, Zhang, Xu, Jiang: "Promoting effects of IL‑23 on myocardial ischemia and reperfusion are associated with increased expression of IL‑17A and upregulation of the JAK2‑STAT3 signaling pathway." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 9309-9316, (2017) (PubMed).

Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Synonyms and alternative names related to JAK2

Janus kinase 2b (jak2b), Janus kinase 2 (JAK2), Janus kinase 2 (Jak2), AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Protein level used designations for JAK2

  • Jak2b kinase
  • PTK JAK2b
  • protein tyrosine kinase JAK2b
  • tyrosine-protein kinase JAK2
  • JAK-2
  • Janus kinase 2 (a protein tyrosine kinase)
  • tyrosine kinase
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