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Browse our anti-Leptin (LEP) Antibodies

Full name:
anti-Leptin Antibodies (LEP)
On are 515 Leptin (LEP) Antibodies from 33 different suppliers available. Additionally we are shipping Leptin Proteins (215) and Leptin Kits (170) and many more products for this protein. A total of 936 Leptin products are currently listed.
LEPD, OB, obese, OBS

All available anti-Leptin Antibodies

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Top referenced anti-Leptin Antibodies

  1. Human Monoclonal Leptin Primary Antibody for EIA, WB - ABIN114695 : Maffei, Halaas, Ravussin, Pratley, Lee, Zhang, Fei, Kim, Lallone, Ranganathan: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. in Nature medicine 1995 (PubMed)
    Show all 6 references for ABIN114695

  2. Human Polyclonal Leptin Primary Antibody for EIA, IF - ABIN358628 : Tank, Jordan, Diedrich, Schroeder, Furlan, Sharma, Luft, Brabant: Bound leptin and sympathetic outflow in nonobese men. in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 4 references for ABIN358628

  3. Human Polyclonal Leptin Primary Antibody for EIA, FACS - ABIN953161 : Friedlander, Li, Fornage, Williams, Lewis, Schreiner, Pletcher, Enquobahrie, Williams, Siscovick: Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study. in Annals of human genetics 2010 (PubMed)
    Show all 2 references for ABIN953161

  4. Human Polyclonal Leptin Primary Antibody for EIA - ABIN318591 : Mantzoros: The role of leptin in human obesity and disease: a review of current evidence. in Annals of internal medicine 1999 (PubMed)

  5. Human Monoclonal Leptin Primary Antibody for IF, ELISA - ABIN1996123 : Sun, Park, Gupta, Holland, Auerbach, Zhang, Goncalves Marangoni, Nicoloro, Czech, Varga, Ploug, An, Scherer: Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction. in Nature communications 2014 (PubMed)

More Antibodies against Leptin Interaction Partners

Mouse (Murine) Leptin (LEP) interaction partners

  1. recent data showing that diet-induced obesity mice may conserve a cellular and physiological response to endogenous leptin, highlights the need to redefine the concept of "leptin resistance"--{REVIEW]

  2. Leptin-deficient mice had lower cancellous bone volume and higher bone marrow adiposity.

  3. FABP4 (show FABP4 Antibodies) reduced the expression of leptin, CPT-1 (show CPT1A Antibodies) and AOX1 (show AOX1 Antibodies) in mice adipocytes

  4. leptin deficiency results in sustained orexigenic stimulation, leading to increased water diffusion parameters

  5. These results suggest the possibility for a direct role for the PDE3B (show PDE3B Antibodies) pathway in mediating leptin action in the hypothalamus.

  6. leptin activates the cGH gene in the presence of chPit-1alpha via several leptin-activated kinases

  7. Data suggest that both adipocyte and somatotrope leptin contribute to the metabolic homeostasis.

  8. Tau effects upon feeding behavior control are complex and involve interactions with a vast gene network, preventing hypothalamic leptin resistance.

  9. These data suggest that exogenous leptin may promote protection during sepsis, and downregulation of the insulin (show INS Antibodies) levels and upregulation of corticosterone may be important mechanisms in the amelioration of LPS (show TLR4 Antibodies)-induced ALI.

  10. Leptin induces expression of the neuropeptide cocaine- and amphetamine-regulated transcript (show CARTPT Antibodies) (CART) in the granulosa cells (GCs (show UGCG Antibodies)) of ovarian follicles both in vitro and in vivo.

Human Leptin (LEP) interaction partners

  1. In pre-obese and obese rheumatoid arthritis patients there is increased production of serum leptin.

  2. advanced glycation end-products levels were positively correlated with disease progression and with leptin

  3. anti-apoptotic effect mediated by MAPK (show MAPK1 Antibodies) and PI3K (show PIK3CA Antibodies) pathways

  4. Leptin level correlated with obesity and health related quality of life in patients with obstructive sleep apnea.

  5. Data suggest that levels of adipokines (adiponectin (show ADIPOQ Antibodies) and leptin), in addition to fasting blood glucose, may serve as biomarkers in screening overweight women with gestational diabetes at high metabolic risk for diabetes type 2 in postpartum period.

  6. the overexpression of leptin in osteoporotic bone marrow stromal cells enhances their capacity to differentiate into osteoblasts and to form bone-like tissue

  7. The leptin, ObR (show LEPR Antibodies) and aromatase (show CYP19A1 Antibodies) protein expression levels were increased in lesions in the vaginal septum and were decreased in the intestine lesions

  8. Serum levels of leptin are independently associated with increased knee cartilage volume in knee osteoarthritis.

  9. In metabolically healthy and unhealthy obese patients, distribution of the G19G, G19A, and A19A genotypes of the LEP gene and G276G, G276T, and T276T genotypes of ADPN (show PNPLA3 Antibodies) gene did not differ.

  10. At day 1 after acute ischemic stroke, serum leptin and leptin/adiponectin (show ADIPOQ Antibodies) ratio were increased and inversely associated with stroke severity.

Pig (Porcine) Leptin (LEP) interaction partners

  1. A high variability of the LEP was detected in the different analysed populations providing new data for the existence of two domestication centres in Asia.

  2. The presence of leptin and ObR-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.

  3. Studied 3'UTR (show UTS2R Antibodies) leptin polymorphism regulatory sequences' affect on gene expression and their association with production traits.

  4. These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.

  5. Data showing changes in expression patterns of LEP/LEPR in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP/LEPR complex at early stages of pregnancy, possibly affecting the attachment process.

  6. Another funning discovery is ob-Rb (show LEPR Antibodies) mRNA in porcine endometrium was mainly negative-regulated by leptin

  7. Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance

  8. Leptin and leptin receptor (show LEPR Antibodies) are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin mRNA expression as well as E and P on leptin secretion by those cells obtained in early pregnancy.

  9. The present study aimed to determine the effects of breed and sex on growth patterns and metabolic features of advanced-pregnancy foetuses from lean and obese/leptin resistant swine.

  10. Locally produced leptin plays a role in the regulation of porcine reproduction at the ovarian level and exerts a direct effect on follicles. Differences in long isoform of leptin receptor (show LEPR Antibodies) gene expression varies in the ovaries of pregnant and cyclic pigs.

Cow (Bovine) Leptin (LEP) interaction partners

  1. Leptin concentrations could be a useful physiological marker for growth and feed efficiency of finishing beef cattle.

  2. Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin-NPY (show NPY Antibodies) and insulin (show INS Antibodies) signaling pathways.

  3. Leptin R25C genotype impacted most traits associated with fatness.

  4. The absence of A80V polymorphism (C --> T at position 95691973 bp of leptin gene) has been established in the genotypes of Ayrshire cattle as compared to Holstein cattle.

  5. Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin and hypothalamic neuropeptide Y (NPY (show NPY Antibodies)) release.

  6. SNP LEP significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR/T945M affected significantly calving interval (P<0.01) only

  7. Results indicated that leptin R25C genotype impacted most traits associated with fatness whereas feeding zilpaterol for 21 d affected weight gain positively but impacted other variables negatively.

  8. There is a strong association between putative favorable allelic variants (SNP) of neuropeptide Y (show NPY Antibodies), leptin, and IGF-1 (show IGF1 Antibodies) genes, and residual feed intake, when animals were grazing on a high-quality, high-availability pasture.

  9. The LEP, IGF2 and CCL2 (show CCL2 Antibodies) genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.

  10. The aim of the study was to determine by immunochemistry the expression of leptin, orexin A and orphanin FQ (show PNOC Antibodies) in the major salivary glands (parotid, submandibular and sublingual) of rat, sheep and cow.

Goat Leptin (LEP) interaction partners

  1. polymorphisms of the LEP gene might be important genetic factors influencing growth traits, and these genetic markers may be useful for future marker-assisted selection programs in goat breeding and production

Rabbit Leptin (LEP) interaction partners

  1. study suggests that increased CSF (show CSF2 Antibodies) leptin, likely from blood-brain barrier breakdown, combined with elevated serum GH and IGF-1 (show IGF1 Antibodies) after traumatic brain injury, leads to accelerated fracture healing

  2. We conclude that offspring from mothers consuming a high fat diet exhibit an adverse cardiovascular profile in adulthood because of altered central hypothalamic sensitivity to leptin and ghrelin (show GHRL Antibodies).

  3. Niacin Reduces serum level and adipose mRNA expression of leptin and up-regulates PPARgamma (show PPARG Antibodies) and CD36 (show CD36 Antibodies) mRNA expression in hypercholesterolemic rabbits.

Horse (Equine) Leptin (LEP) interaction partners

  1. Leptin metabolism in obese ponies following a return to free feeding after a period of food deprivation is reported.

  2. Plasma levels of leptin (as well as glucose, insulin (show INS Antibodies), and growth hormone (show GH1 Antibodies)) are highly correlated with the duration of winter anovulatory phase.

  3. GHRL (show GHRL Antibodies), LEP, ADIP (show SSX2IP Antibodies), INS (show INS Antibodies) and CORT (show CORT Antibodies) concentrations were measured using radioimmunoassay

  4. positive correlation between leptin and estradiol led us to suggest that leptin hormone plays an important role in ovulation of the first postpartum estrus in mares

Rhesus Monkey Leptin (LEP) interaction partners

  1. The effects of exogenous human kisspeptin-10 (KP10) were studied on three important adipokines, namely, adiponectin (show ADIPOQ Antibodies), leptin, and resistin (show RETN Antibodies) in a set of four chair-restraint habituated intact adult male rhesus monkeys.

  2. results do not support a role for reduced leptin secretion in anovulation induced by dietary restriction

Leptin (LEP) Antigen Profile

Antigen Summary

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Alternative names and synonyms associated with Leptin (LEP)

  • leptin (Lep) antibody
  • leptin (LEP) antibody
  • leptin (lep) antibody
  • LEPD antibody
  • OB antibody
  • obese antibody
  • OBS antibody

Protein level used designations for anti-Leptin (LEP) Antibodies

obesity factor , leptin (murine obesity homolog) , leptin (obesity homolog, mouse) , obese protein , obese, mouse, homolog of , obese

16846 Mus musculus
3952 Homo sapiens
25608 Rattus norvegicus
443534 Ovis aries
396832 Sus scrofa
280836 Bos taurus
100860794 Capra hircus
100008747 Oryctolagus cuniculus
373955 Gallus gallus
403616 Canis lupus familiaris
100034042 Equus caballus
493838 Felis catus
449638 Pan troglodytes
100716751 Cavia porcellus
698728 Macaca mulatta
548631 Takifugu rubripes
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