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Browse our anti-Leptin (LEP) Antibodies

Full name:
anti-Leptin Antibodies (LEP)
On are 608 Leptin (LEP) Antibodies from 34 different suppliers available. Additionally we are shipping Leptin Proteins (219) and Leptin Kits (187) and many more products for this protein. A total of 1050 Leptin products are currently listed.
LEPD, OB, obese, OBS

All available anti-Leptin Antibodies

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Top referenced anti-Leptin Antibodies

  1. Human Monoclonal Leptin Primary Antibody for EIA, WB - ABIN114695 : Maffei, Halaas, Ravussin, Pratley, Lee, Zhang, Fei, Kim, Lallone, Ranganathan: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. in Nature medicine 1995 (PubMed)
    Show all 6 references for ABIN114695

  2. Human Polyclonal Leptin Primary Antibody for EIA, IHC (fro) - ABIN115495 : Considine, Sinha, Heiman, Kriauciunas, Stephens, Nyce, Ohannesian, Marco, McKee, Bauer: Serum immunoreactive-leptin concentrations in normal-weight and obese humans. in The New England journal of medicine 1996 (PubMed)
    Show all 5 references for ABIN115495

  3. Human Polyclonal Leptin Primary Antibody for EIA, IF - ABIN358628 : Tank, Jordan, Diedrich, Schroeder, Furlan, Sharma, Luft, Brabant: Bound leptin and sympathetic outflow in nonobese men. in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 4 references for ABIN358628

  4. Human Polyclonal Leptin Primary Antibody for EIA, FACS - ABIN953161 : Friedlander, Li, Fornage, Williams, Lewis, Schreiner, Pletcher, Enquobahrie, Williams, Siscovick: Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study. in Annals of human genetics 2010 (PubMed)
    Show all 2 references for ABIN953161

  5. Human Polyclonal Leptin Primary Antibody for EIA - ABIN318591 : Mantzoros: The role of leptin in human obesity and disease: a review of current evidence. in Annals of internal medicine 1999 (PubMed)

  6. Human Monoclonal Leptin Primary Antibody for IF, ELISA - ABIN1996123 : Sun, Park, Gupta, Holland, Auerbach, Zhang, Goncalves Marangoni, Nicoloro, Czech, Varga, Ploug, An, Scherer: Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction. in Nature communications 2014 (PubMed)

More Antibodies against Leptin Interaction Partners

Mouse (Murine) Leptin (LEP) interaction partners

  1. Leptin stimulation led to TNFalpha (show TNF Antibodies) production under both in vitro and in vivo conditions, and diurnal fluctuation of leptin concentrations in the cerebrospinal fluid predicted the circadian changes of TNFalpha (show TNF Antibodies) gene expression in the hypothalamus.

  2. geniposide may regulate tau phosphorylation through leptin signaling

  3. Activated FXR (show NR1H4 Antibodies) inhibits leptin signaling and counteracts tumor-promoting activities of cancer-associated fibroblasts in breast malignancy.

  4. this study shows that knockdown of leptin in hepatoma cells caused higher Treg activity and lower CD8 (show CD8A Antibodies)+ T-cell response in the mouse hepatocellular carcinoma allograft model.

  5. Hexim1 (show HEXIM1 Antibodies) selectively modulates leptin-mediated signal transduction pathways in the hypothalamus.

  6. The weight-reducing hypophagic effects of leptin are not augmented through its thermogenic effect.

  7. ime-specific changes in promoter associated DNA methyltransferases may be associated with the regulation of leptin expression.

  8. These data suggest that the heavy infiltration of adipocytes and the presence of leptin in the thymuses of tumor bearers may affect normal thymopoiesis, leading to the impairment of T cell development observed during tumor-induced thymic atrophy.

  9. Leptin resistance-induced obesity and diabetes accelerates the development of tau pathology

  10. Obese leptin-deficient (ob/ob) mice demonstrate defects in upper airway structural and neuromuscular control

Human Leptin (LEP) interaction partners

  1. We investigated the association of the polymorphisms rs7799039 (LEP) in a case-control study in Euro-Brazilians with gestational diabetes. The minor allele frequencies, for healthy and gestational diabetes, respectively, for the A-allele (LEP gene rs7799039) were 40.3% (95%CI = 35-45%) vs 36.6% (95%CI = 31-42%), P = 0.345; Genotype comparisons showed no significant difference.

  2. The polymorphisms of miRNA-27a rs895819 A/G and Leptin rs7799039 G/A may contribute to an increased risk of recurrent spontaneous abortion.

  3. Low L/A [ leptin to adiponectin (show ADIPOQ Antibodies) ] ratio is a predictor for the regression of metabolic syndrome. The L/A [leptin to adiponectin (show ADIPOQ Antibodies)] ratio could be a useful clinical marker for management of high-risk individuals with metabolic syndrome.

  4. In women with known CAD (show CAD Antibodies), increased leptin concentration is useful for predicting cardiovascular death and non-fatal myocardial infarction

  5. Circulating Leptin and Resistin (show RETN Antibodies), but not Adiponectin (show ADIPOQ Antibodies), levels positively correlate with rheumatoid arthritis clinical activity in a manner independent of the subject's BMI.

  6. reduced type I interferon (show IFNA Antibodies) production in obesity is caused by SOCS3 (show SOCS3 Antibodies) overexpression as well as tolerance induced by leptin

  7. Leptin to insulin (show INS Antibodies) and adiponectin (show ADIPOQ Antibodies) to endothelin ratios are novel derived biomarkers useful for noninvasive diagnostics of initial stages of coronary lesions in patients with coronary artery disease.

  8. Results showed that exposure to maternal gestational diabetes was associated with increased ADIPOQ (show ADIPOQ Antibodies) methylation and decreased ADIPOQ (show ADIPOQ Antibodies) and RETN (show RETN Antibodies) gene expression. Especially for ADIPOQ (show ADIPOQ Antibodies) methylation and expression, findings support an epigenetic mechanisms controlling adipokine gene expression may be involved in fetal programming of type 2 diabetes mellitus.

  9. Only leptin was relevant as a predictor of weight gain at the 3-month endpoint.

  10. leptin-LepRb (show LEPR Antibodies) plays an important role in the pathogenesis and depression in gastric cancer

Pig (Porcine) Leptin (LEP) interaction partners

  1. The lack of effect of heat stress on the expression of leptin suggests that this peptide may not be involved in the reduction of feed intake of HS acclimated pigs.

  2. A high variability of the LEP was detected in the different analysed populations providing new data for the existence of two domestication centres in Asia.

  3. The presence of leptin and ObR-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.

  4. Studied 3'UTR (show UTS2R Antibodies) leptin polymorphism regulatory sequences' affect on gene expression and their association with production traits.

  5. These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.

  6. Data showing changes in expression patterns of LEP/LEPR in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP/LEPR complex at early stages of pregnancy, possibly affecting the attachment process.

  7. Another funning discovery is ob-Rb (show LEPR Antibodies) mRNA in porcine endometrium was mainly negative-regulated by leptin

  8. Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance

  9. Leptin and leptin receptor (show LEPR Antibodies) are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin mRNA expression as well as E and P on leptin secretion by those cells obtained in early pregnancy.

  10. The present study aimed to determine the effects of breed and sex on growth patterns and metabolic features of advanced-pregnancy foetuses from lean and obese/leptin resistant swine.

Cow (Bovine) Leptin (LEP) interaction partners

  1. The effects of a single nucleotide polymorphism of leptin on weight gain and body composition are reported.

  2. A leptin SNP (LEPg.978) was significantly associated with a weight at one year.

  3. The results of this study suggest that leptin physiology could be a candidate for mechanisms that contribute to feed intake and feed efficiency variation in beef cattle.

  4. Leptin concentrations could be a useful physiological marker for growth and feed efficiency of finishing beef cattle.

  5. Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin-NPY (show NPY Antibodies) and insulin (show INS Antibodies) signaling pathways.

  6. Leptin R25C genotype impacted most traits associated with fatness.

  7. The absence of A80V polymorphism (C --> T at position 95691973 bp of leptin gene) has been established in the genotypes of Ayrshire cattle as compared to Holstein cattle.

  8. Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin and hypothalamic neuropeptide Y (NPY (show NPY Antibodies)) release.

  9. SNP LEP significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR/T945M affected significantly calving interval (P<0.01) only

  10. Results indicated that leptin R25C genotype impacted most traits associated with fatness whereas feeding zilpaterol for 21 d affected weight gain positively but impacted other variables negatively.

Goat Leptin (LEP) interaction partners

  1. polymorphisms of the LEP gene might be important genetic factors influencing growth traits, and these genetic markers may be useful for future marker-assisted selection programs in goat breeding and production

Rabbit Leptin (LEP) interaction partners

  1. study suggests that increased CSF (show CSF2 Antibodies) leptin, likely from blood-brain barrier breakdown, combined with elevated serum GH and IGF-1 (show IGF1 Antibodies) after traumatic brain injury, leads to accelerated fracture healing

  2. We conclude that offspring from mothers consuming a high fat diet exhibit an adverse cardiovascular profile in adulthood because of altered central hypothalamic sensitivity to leptin and ghrelin (show GHRL Antibodies).

  3. Niacin Reduces serum level and adipose mRNA expression of leptin and up-regulates PPARgamma (show PPARG Antibodies) and CD36 (show CD36 Antibodies) mRNA expression in hypercholesterolemic rabbits.

Horse (Equine) Leptin (LEP) interaction partners

  1. Positive correlations were found between leptin and total lipids, triglycerides, VLDLs, Total-Chol, and LDLs.

  2. Leptin metabolism in obese ponies following a return to free feeding after a period of food deprivation is reported.

  3. Plasma levels of leptin (as well as glucose, insulin (show INS Antibodies), and growth hormone (show GH1 Antibodies)) are highly correlated with the duration of winter anovulatory phase.

  4. GHRL (show GHRL Antibodies), LEP, ADIP (show SSX2IP Antibodies), INS (show INS Antibodies) and CORT (show CORT Antibodies) concentrations were measured using radioimmunoassay

  5. positive correlation between leptin and estradiol led us to suggest that leptin hormone plays an important role in ovulation of the first postpartum estrus in mares

Rhesus Monkey Leptin (LEP) interaction partners

  1. The effects of exogenous human kisspeptin-10 (KP10) were studied on three important adipokines, namely, adiponectin (show ADIPOQ Antibodies), leptin, and resistin (show RETN Antibodies) in a set of four chair-restraint habituated intact adult male rhesus monkeys.

  2. results do not support a role for reduced leptin secretion in anovulation induced by dietary restriction

Leptin (LEP) Antigen Profile

Antigen Summary

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Alternative names and synonyms associated with Leptin (LEP)

  • leptin (Lep) antibody
  • leptin (LEP) antibody
  • leptin (lep) antibody
  • LEPD antibody
  • OB antibody
  • obese antibody
  • OBS antibody

Protein level used designations for anti-Leptin (LEP) Antibodies

obesity factor , leptin (murine obesity homolog) , leptin (obesity homolog, mouse) , obese protein , obese, mouse, homolog of , obese

16846 Mus musculus
3952 Homo sapiens
25608 Rattus norvegicus
443534 Ovis aries
396832 Sus scrofa
280836 Bos taurus
100860794 Capra hircus
100008747 Oryctolagus cuniculus
373955 Gallus gallus
403616 Canis lupus familiaris
100034042 Equus caballus
493838 Felis catus
449638 Pan troglodytes
100716751 Cavia porcellus
698728 Macaca mulatta
548631 Takifugu rubripes
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