Leptin antibody (AA 8-37)
- Target See all Leptin (LEP) Antibodies
- Leptin (LEP)
- AA 8-37
- This Leptin antibody is un-conjugated
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- Cross-Reactivity (Details)
- Expected species reactivity: Mouse
- Antigen affinity purified
- A portion of amino acids 8-37 from the human protein was used as the immunogen for this LEP antibody.
- Ig Fraction
- Application Notes
- Titration of the LEP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
- For Research Use only
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- -20 °C
- Storage Comment
- Aliquot the LEP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- Leptin (LEP)
- Alternative Name
- Leptin (LEP Products)
- ob antibody, obese antibody, LEPD antibody, OB antibody, OBS antibody, leptin antibody, Lep antibody, LEP antibody, lep antibody
- This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq].
- JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process