Browse our RAF1 Proteins (RAF1)

Full name:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 Proteins (RAF1)
On www.antibodies-online.com are 27 V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Proteins from 9 different suppliers available. Additionally we are shipping RAF1 Antibodies (837) and RAF1 Kits (25) and many more products for this protein. A total of 930 RAF1 products are currently listed.
Synonyms:
6430402F14Rik, AA990557, Afr-1, Afr1, BB129353, c-Raf, CRAF, Craf1, D830050J10Rik, mKIAA0854, NS5, Raf, Raf-1, RAF1, v-Raf
list all proteins Gene Name GeneID UniProt
RAF1 5894 P04049
RAF1 110157 Q99N57
RAF1 24703 P11345

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RAF1 Proteins (RAF1) by Origin

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Top referenced RAF1 Proteins

  1. Human RAF1 Protein expressed in Wheat germ - ABIN1317314 : Rodríguez-Muñoz, de la Torre-Madrid, Sánchez-Blázquez, Garzón: NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor. in Antioxidants & redox signaling 2011 (PubMed)

More Proteins for RAF1 Interaction Partners

Zebrafish V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) interaction partners

  1. cdk10 (show CDK10 Proteins) has roles in vertebrate development and a critical function in neurogenesis by modulation of raf1a expression

  2. Our results indicate that Rb-Raf-1 interaction plays an important role in spontaneous hair cell regeneration in zebrafish

  3. Zebrafish embryos with morpholino knockdown of raf1 demonstrated the need for raf1 for the development of normal myocardial structure and function.

  4. analysis of the roles of Raf- and PI3K-signalling pathways in melanoma

Xenopus laevis V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) interaction partners

  1. Both c-Raf and B-Raf (show BRAF Proteins) are required for Ras-induced MEK1 (show MAP2K1 Proteins) and p42 (show EPB42 Proteins) MAP kinase (show MAPK1 Proteins) activation.

Human V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) interaction partners

  1. RhoA (show RHOA Proteins)/ROCK and Raf-1/CK2 (show CSNK2A1 Proteins) pathway are responsible for TNF-alpha (show TNF Proteins)-mediated endothelial cytotoxicity via regulation of the vimentin (show VIM Proteins) cytoskeleton.

  2. Although Raf-1 gene is not mutated, an abnormality of Raf-1 kinase feedback regulation enhances its antiapoptotic function, and Raf-1 can still be a pharmaceutical target to increase chemotherapy or radiotherapy sensitivity in these cancer cells.

  3. ZHX2 (show ZHX2 Proteins) expression in renal cell carcinoma (show MOK Proteins)

  4. RAF1 plays a critical role in maintaining the transformed phenotype of CRC cells, including those with mutated KRAS.

  5. Zhx2 (show ZHX2 Proteins) is a novel regulator of Mup expression; Zhx2 (show ZHX2 Proteins) activates as well as represses expression of target genes

  6. This finding suggests that stringent assemblage of Hsp90 (show HSP90 Proteins) keeps CRAF kinase equipped for participating in the MAPK (show MAPK1 Proteins) pathway. Thus, the role of Hsp90 (show HSP90 Proteins) in CRAF maturation and activation acts as a limiting factor to maintain the function of a strong client like CRAF kinase.

  7. Oncogenic NFIA:RAF1 fusion activation of the MAPK (show MAPK1 Proteins) pathway is associated with pilocytic astrocytoma.

  8. IGF2BP2 (show IGF2BP2 Proteins) as a post-transcriptional regulatory mRNA-binding factor, interfering with Raf-1 degradation by miR (show MLXIP Proteins)-195, that contributes to Colorectal carcinogenesis.

  9. Data show that when microRNA miR (show MLXIP Proteins)-125b was over-expressed in THP-1 macrophages, the expression of Raf1 proto-oncogene (show RAB1A Proteins) serine/threonine protein kinase (RAF1) was reduced to promote the apoptosis of macrophages.

  10. Data show that Griffipavixanthone (GPX (show GPX1 Proteins)), a dimeric xanthone isolated from Garcinia esculenta, is a B-RAF (show SNRPE Proteins) and C-RAF inhibitor against esophageal cancer cells.

Cow (Bovine) V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) interaction partners

  1. data suggest that G alpha(i3), Shc (show SHC1 Proteins), Grb2 (show GRB2 Proteins), Ras, and Raf-1 link Src (show SRC Proteins) to activation of MAPK (show MAPK1 Proteins) and to the AT(2)-dependent increase in eNOS (show NOS3 Proteins) expression in PAECs

Mouse (Murine) V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) interaction partners

  1. Zhx2 (show ZHX2 Proteins) is a novel regulator of Mup expression; Zhx2 (show ZHX2 Proteins) activates as well as represses expression of target genes

  2. A- and B-Raf ablation in chondrocytes does not alter skeletal development, whereas ablation of C-Raf decreases hypertrophic chondrocyte apoptosis and impairs vascularization of the growth plate. However, ablation of C-Raf does not impair phosphate-induced ERK1/2 phosphorylation in vitro, but leads to rickets by decreasing VEGF protein stability.

  3. We confirmed that Raf1(L613V) knock-in confers a NS-like phenotype, including cardiac hypertrophy. Active RSK3 (show RPS6KA2 Proteins) was increased in Raf1(L613V) mice. Constitutive RSK3 (show RPS6KA2 Proteins) gene deletion prevented the Raf1(L613V)-dependent concentric growth in width of the cardiac myocyte and attenuated cardiac hypertrophy in female mice.

  4. C-Raf involves in osteoblast survival in response to mechanical stress.

  5. Dual inhibition of c-Raf and soluble epoxide hydrolase (show EPHX2 Proteins) by t-CUPM prevents mutant KrasG12D-initiated murine pancreatic carcinoma growth.

  6. Simultaneous inhibition of sEH (show EPHX2 Proteins) and c-RAF prevents chronic pancreatitis and murine pancreatic intraepithelial neoplasia in LSL-KrasG(1)(2)D/Pdx-1 (show PDX1 Proteins)-Cre mice.

  7. under normal physiological conditions, PTEN suppresses AKT (show AKT1 Proteins) activity to maintain activation of the RAF1/ERK (show EPHB2 Proteins) signaling pathway, which in turn maintains normal function of the initial segment and therefore, normal sperm maturation.

  8. these data indicate that B-RAF (show SNRPE Proteins) is an important factor in oncogenic C-RAF-mediated tumorigenesis.

  9. PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.

  10. Raf-MAPK (show MAPK1 Proteins)-dependent psoriatic-like epidermal hyperplasia requires Stat3 (show STAT3 Proteins) signaling in keratinocytes

RAF1 Protein Profile

Protein Summary

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.

Alternative names and synonyms associated with RAF1

  • v-raf-1 murine leukemia viral oncogene homolog 1a (raf1a)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (raf1)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (LOC100341921)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (LOC100347407)
  • raf protein (c-raf)
  • v-raf-leukemia viral oncogene 1 (Raf1)
  • zinc fingers and homeoboxes 2 (ZHX2)
  • zinc fingers and homeoboxes 2 (Zhx2)
  • 6430402F14Rik protein
  • AA990557 protein
  • Afr-1 protein
  • Afr1 protein
  • BB129353 protein
  • c-Raf protein
  • CRAF protein
  • Craf1 protein
  • D830050J10Rik protein
  • mKIAA0854 protein
  • NS5 protein
  • Raf protein
  • Raf-1 protein
  • RAF1 protein
  • v-Raf protein

Protein level used designations for RAF1

RAF proto-oncogene serine/threonine-protein kinase , murine leukemia viral oncogene homolog , serine/threonine protein kinase RAF1 , v-raf-1 murine leukemia viral oncogene homolog 1 , cRaf , proto-oncogene c-RAF , raf-1 , RAF proto-oncogene serine/threonine-protein kinase-like , Oncogene RAF1 , raf proto-oncogene serine/threonine protein kinase , C-RAF , MIL proto-oncogene serine/threonine-protein kinase , RAF-1 , c-mil protein , murine leukemia viral (v-raf-1) oncogene homolog 1 , Craf1 transforming , murine sarcoma 3611 oncogene 1 , sarcoma 3611 oncogene , v-raf-1 leukemia viral oncogene 1 , murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV) , AFP regulator 1 , alpha-fetoprotein regulator 1 , regulator of AFP , transcription factor ZHX2 , zinc finger and homeodomain protein 2 , zinc fingers and homeoboxes protein 2 , zinc-fingers and homeoboxes 2 , alpha fetoprotein regulation 1, adult

GENE ID SPECIES
30716 Danio rerio
460182 Pan troglodytes
549871 Xenopus (Silurana) tropicalis
694725 Macaca mulatta
100173732 Pongo abelii
100341921 Oryctolagus cuniculus
100347407 Oryctolagus cuniculus
100415300 Callithrix jacchus
100482255 Ailuropoda melanoleuca
100582599 Nomascus leucogenys
397857 Xenopus laevis
5894 Homo sapiens
396245 Gallus gallus
484648 Canis lupus familiaris
521196 Bos taurus
110157 Mus musculus
24703 Rattus norvegicus
22882 Homo sapiens
387609 Mus musculus
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