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Browse our CRHR2 Proteins (CRHR2)

Full name:
Corticotropin Releasing Hormone Receptor 2 Proteins (CRHR2)
On are 6 Corticotropin Releasing Hormone Receptor 2 (CRHR2) Proteins from 2 different suppliers available. Additionally we are shipping CRHR2 Antibodies (171) and CRHR2 Kits (19) and many more products for this protein. A total of 204 CRHR2 products are currently listed.
CRF-R2, CRF-RB, CRF2, Crf2r, Crfr2, CRFR2alpha, CRFR2beta, CRH-R2, crhr2-A, HM-CRF
list all proteins Gene Name GeneID UniProt
CRHR2 1395 Q13324
CRHR2 12922  
Rat CRHR2 CRHR2 64680 P47866

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CRHR2 Proteins (CRHR2) by Origin

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More Proteins for CRHR2 Interaction Partners

Horse (Equine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

  1. The expression of UCN, CRHR1, CRHR2 and CRHBP by immunohistochemistry, Western blot and reverse transcription with the polymerase chain reaction (RT-PCR) in the horse thyroid gland, was investigated

Human Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

  1. In deep infiltrating endometriotic lesions, CRH (show CRH Proteins), Ucn and CRH-R2 mRNA levels were significantly higher than in ovarian endometrioma.

  2. Endogenous CRF (show CRH Proteins) may be involved in the pathogenesis of ischemia/reperfusion-induced enteritis, possibly via the activation of peripheral CRF (show CRH Proteins) receptor 2

  3. This study showed that two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD subjects with sexual and physical abuse.

  4. found associations between CRHR2 genotypes and haplotypes and negative emotion in IBS patients and controls

  5. Wound healing and signal transducer and activator of transcription 3 activity were elevated in CRHR2-overexpressing cells after urocortin 2 and IL-6 treatment, suggesting advanced healing progression

  6. This study demonstrated that CRF2 Receptor Deficiency Eliminates the Long-Lasting Vulnerability of Motivational States Induced by Opiate Withdrawal.

  7. D1 and CRF2 alpha receptors are capable of heterodimerization in living cells. D1 /CRF2 alpha receptor heteromerization might account, at least in part, for the complex physiological interactions established between dopamine and CRH (show CRH Proteins).

  8. HSF2 element confers estrogen up-regulation of CRHR2 transcription and estrogen increases CRHR2 transcription via induction of HSF2 demethylation.

  9. Results suggest CRHR-2 variants may affect risk for PTSD in women by attenuating the stress response and reducing symptoms of the disorder.

  10. These results fail to provide support for an association of CRHR1 (show CRHR1 Proteins) and CRHR2 with personality traits in a Japanese adult population.

Mouse (Murine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

  1. Study demonstrated that CRF1 receptor (show CRHR1 Proteins)-deficiency prolongs whereas CRF2 receptor-deficiency shortens the duration of recognition memory deficits induced by morphine discontinuation, unraveling opposite roles for the two known CRF (show CRH Proteins) receptor subtypes in cognitive dysfunction associated with opiate withdrawal.

  2. results indicate that long-term UVA eye irradiation led to increased gp91phox (show CYBB Proteins)-derived ROS (show ROS1 Proteins) in the brain and the increased expression of urocortin 2 (show UTS2 Proteins) and CRHR (show CRHR1 Proteins) type 2, resulting in photoaging; however, further studies are needed to confirm these findings

  3. Crhr2(-/-) mice showed increased mortality in the dextran sodium sulfate healing protocol

  4. the inhibitory effect of CRFR2 signaling on insulin (show INS Proteins) action is mediated by cAMP in a mammalian target of rapamycin (show FRAP1 Proteins)-dependent manner.

  5. This study aims to investigate the cellular localization of CRF (show CRH Proteins) and UCNs in the ileum and to explore whether and how this cellular expression is altered in conditions of intestinal Schistosoma mansoni-induced inflammation.

  6. cPLA2 (show PLA2G4A Proteins) participates in CRHR1 (show CRHR1 Proteins)-induced apoptosis and CRHR2-inhibited apoptosis.

  7. Data suggest that signal transduction via ghrelin (show GHRL Proteins) and Crhr2 plays role in regulation of muscle glucose metabolism; Ghsr1a (ghrelin receptor (show GHSR Proteins) type 1A) was not detected in mouse myoblast cell line (C2C12) investigated.

  8. The receptors' binding specificity and structural studies were performed using full-length human CRFR1alpha and mouse CRFR2beta as well as fragments lacking the N-terminal extracellular domain.

  9. estrogens act on ERalpha (show ESR1 Proteins) to up-regulate CRHR2 expression in cardiomyocytes.

  10. These results provide initial evidence of a gender-independent and specific role for the CRF2 receptor in the motivational effects of opiate withdrawal.

Cow (Bovine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

  1. These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN, CRHR1 and CRHR2 and that UCN plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.

  2. CRHR1 (show CRHR1 Proteins) and CRHR2 are expressed in the bovine adrenal gland.

Pig (Porcine) Corticotropin Releasing Hormone Receptor 2 (CRHR2) interaction partners

  1. CRFr1 (show CRHR1 Proteins) activation mediates intestinal mucosa barrier dysfunction and hypersecretion in early-weaned piglets, whereas CRFr2 activation may be responsible for novel protective properties in the porcine intestine in response to early life stress.

CRHR2 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with CRHR2

  • corticotropin releasing hormone receptor 2 (CRHR2)
  • corticotropin releasing hormone receptor 2 (LOC100219758)
  • corticotropin releasing hormone receptor 2 (Crhr2)
  • corticotropin releasing hormone receptor 2 (crhr2)
  • CRF-R2 protein
  • CRF-RB protein
  • CRF2 protein
  • Crf2r protein
  • Crfr2 protein
  • CRFR2alpha protein
  • CRFR2beta protein
  • CRH-R2 protein
  • crhr2-A protein
  • HM-CRF protein

Protein level used designations for CRHR2

corticotropin releasing hormone receptor 2 , corticotropin-releasing factor receptor 2-like , CRF2 receptor, beta isoform , CRH-R2 , corticotropin-releasing factor receptor 2 , CRF 2 receptor , CRF-R-2 , CRF-RB , CRFR-2 , CRH-R-2 , corticotropin releasing factor receptor type 2 beta , corticotropin-releasing factor 2 , corticotropin-releasing hormone receptor 2 , CRF-R 2 , CRF-R2 , CRF2 , CRH-R 2 , corticotrophin releasing hormone receptor 2 , corticotropin-releasing factor receptor subtype 2 , putative corticotropin-releasing hormone receptor type 2

697404 Macaca mulatta
748363 Pan troglodytes
100055029 Equus caballus
100219758 Taeniopygia guttata
100443520 Pongo abelii
100476464 Ailuropoda melanoleuca
100602303 Nomascus leucogenys
1395 Homo sapiens
12922 Mus musculus
64680 Rattus norvegicus
395105 Gallus gallus
482384 Canis lupus familiaris
521831 Bos taurus
100240719 Sus scrofa
378608 Xenopus laevis
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