CRHR2 Protein (AA 1-411) (His tag)
custom-made
CRHR2
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all CRHR2 Proteins
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-411
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CRHR2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Crhr2 Protein expressed in mammalian cells.
- Sequence
- MDAALLLSLL EANCSLALAE ELLLDGWGVP PDPEGPYTYC NTTLDQIGTC WPQSAPGALV ERPCPEYFNG IKYNTTRNAY RECLENGTWA SRVNYSHCEP ILDDKQRKYD LHYRIALIVN YLGHCVSVVA LVAAFLLFLV LRSIRCLRNV IHWNLITTFI LRNIAWFLLQ LIDHEVHEGN EVWCRCITTI FNYFVVTNFF WMFVEGCYLH TAIVMTYSTE HLRKWLFLFI GWCIPCPIII AWAVGKLYYE NEQCWFGKEA GDLVDYIYQG PVMLVLLINF VFLFNIVRIL MTKLRASTTS ETIQYRKAVK ATLVLLPLLG ITYMLFFVNP GEDDLSQIVF IYFNSFLQSF QGFFVSVFYC FFNGEVRAAL RKRWHRWQDH HALRVPVARA MSIPTSPTRI SFHSIKQTAA V Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product CRHR2 Protein
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Corticotropin Releasing Hormone Receptor 2 (CRHR2) (AA 1-411) protein (GST tag)
CRHR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Alternative Name
- Crhr2 (CRHR2 Products)
- Background
- Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (CRF-RB) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2),FUNCTION: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
- Molecular Weight
- 47.6 kDa
- UniProt
- Q60748
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour
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