Browse our MUC1 Proteins (MUC1)

Full name:
Mucin 1, Cell Surface Associated Proteins (MUC1)
On www.antibodies-online.com are 53 Mucin 1, Cell Surface Associated (MUC1) Proteins from 13 different suppliers available. Additionally we are shipping MUC1 Antibodies (1402) and MUC1 Kits (102) and many more products for this protein. A total of 1587 MUC1 products are currently listed.
Synonyms:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, Muc-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
list all proteins Gene Name GeneID UniProt
MUC1 4582 P15941
MUC1 24571  
MUC1 17829 Q02496

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MUC1 Proteins (MUC1) by Origin

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Top referenced MUC1 Proteins

  1. Human MUC1 Protein expressed in Human Cells - ABIN2005053 : Parry, Hanisch, Leir, Sutton-Smith, Morris, Dell, Harris: N-Glycosylation of the MUC1 mucin in epithelial cells and secretions. in Glycobiology 2006 (PubMed)
    Show all 4 references for 2005053

  2. Human MUC1 Protein expressed in Wheat germ - ABIN1311631 : Lu, Ladd, Feng, Wu, Goodell, Pitteri, Li, Prentice, Hanash, Disis: Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera. in Cancer prevention research (Philadelphia, Pa.) 2012 (PubMed)
    Show all 2 references for 1311631

More Proteins for MUC1 Interaction Partners

Human Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. immunoexpression of different epitopes (external and cytoplasmic) of MUC1 expression are altered in tubes with ectopic pregnancy compared with normal tubes, suggesting an association to explain its etiology

  2. Data show that triple-negative breast cancer (TNBC) patients with pre-therapeutic serum high levels of both carcinoembryonic antigen (CEA (show CEACAM5 Proteins)) and cancer antigen 15-3 (CA15-3) had shorter overall survival (OS) and disease-free survival (DFS (show FST Proteins)) rates than those in the low-level groups.

  3. MUC1 expression correlates with tumor metastatic recurrence in postoperative esophageal squamous cell cancer patients

  4. Differences in the apparent expression levels of CEA (show CEACAM5 Proteins), CA153 and CA125 (show MUC16 Proteins) in patients with nipple discharge and healthy persons were validated.

  5. Detection of MUC1 and HS3ST2 (show HS3ST2 Proteins) promoter methylation status appears to be useful molecular markers for assessing the progressive state of the disease and could be helpful in discriminating breast cancer molecular subtypes. These results validate the methylation-based microarray analysis, thus trust their output in the future.

  6. Data show that added synthetic long peptides derived from widely expressed oncoproteins MUC1 and HER2/neu (show ERBB2 Proteins) were reliably presented to CD4 (show CD4 Proteins)+ T-cells and cross-presented to CD8 (show CD8A Proteins)+ T-cells.

  7. MUC1 is aberrantly overexpressed on the entire tumor cell surface of most human cancers; MUC1 induces tamoxifen resistance in estrogen receptor (show ESR1 Proteins)-positive breast cancer

  8. MUC1 protein expression was associated with adverse pathological features, although it was not an independent predictor of outcome after radical prostatectomy.

  9. Findings provide evidence that rs4072037 MUC1 does not have a significant impact on the pathogenesis or prognosis of lung adenocarcinoma (ADC (show ADC Proteins)), whereas KL-6 serum levels, which might reflecting the molecular length of MUC1, are significantly associated with lung ADC (show ADC Proteins).

  10. The data demonstrated variation in corneal epithelial membrane-associated mucin (show SLC13A2 Proteins) expression between species, with the rabbit having a distinct expression pattern. These differences may be reflective of the environment, pathogen exposure or tear film dynamics of the respective species.

Pig (Porcine) Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. The results indicate that Muc1 gene is significantly associated with litter size in pigs.

  2. The epiblast expressed epithelial markers, MUC1 and E-CADHERIN (show CDH1 Proteins), and the pluripotency markers, DNMT3B (show DNMT3B Proteins) and CRIPTO (show TDGF1 Proteins).

Cow (Bovine) Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. Endometrial expressions of MUC1 and cytokine genes differed among normal, fertile versus diseased, and subfertile dairy cows.

  2. Bovine Muc1 prevents binding of bacteria to human intestinal cells and may have a role in preventing the binding of common enteropathogenic bacteria to human intestinal epithelial surfaces.

  3. concluded that bovine Muc1 protein is probably an inducible innate immune effector and an important component of the first line of defense against bacterial invasion of epithelial surfaces

Mouse (Murine) Mucin 1, Cell Surface Associated (MUC1) interaction partners

  1. Gp91phox (show CYBB Proteins) NADPH oxidase (show NOX1 Proteins) modulates litter size by up-regulating mucin1 expression in the uterus of mice.

  2. In summary, we have demonstrated that MUC1 on immune cells is a novel regulator of the NLRP3 (show NLRP3 Proteins) inflammasome, and propose this is mediated by an interaction with signalling components at the cytoplasmic domains of TLRs that involves inhibition of IRAK4 (show IRAK4 Proteins) activation.

  3. MUC1 regulates IL-1beta (show IL1B Proteins) secretion induced by the NLRP3 (show NLRP3 Proteins)-activating bacteria Haemophilus influenzae but not bacteria that activate other inflammasomes.

  4. Muc1 protection during acute kidney injury proceeds by enhancing both the HIF-1 (show HIF1A Proteins) and beta-catenin (show CTNNB1 Proteins) protective pathways.

  5. MAMs MUC1 and MUC16 (show MUC16 Proteins) contribute to the maintenance of immune homeostasis at the ocular surface by limiting TLR-mediated innate immune responses.

  6. the present study provides evidence that Muc1 is a direct target of let-7a and let-7b in mouse uteri during embryo implantation.

  7. Anatomical site-specific Cre-loxP recombination throughout the genital tract of MUC1KrasPten mice leads to MUC1 positive genital tract tumors, and the development of these tumors is influenced by the anatomical environment

  8. Muc1 clearly plays a significant role in enhancing the hypoxia-inducible transcription factors protective pathway during ischemic insult and recovery in kidney epithelia

  9. Epithelial Muc1 is important for gastric mucosa healing by enhancing cell migration and proliferation.

  10. the present study provides evidence that MUC1 is a direct target of miRNA-199a during embryo implantation.

MUC1 Protein Profile

Protein Summary

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MUC1

  • mucin 1, cell surface associated (MUC1)
  • mucin 1, cell surface associated (Muc1)
  • mucin 1, transmembrane (Muc1)
  • CA 15-3 protein
  • CD227 protein
  • EMA protein
  • H23AG protein
  • KL-6 protein
  • MAM6 protein
  • MCKD1 protein
  • Muc-1 protein
  • MUC-1/SEC protein
  • MUC-1/X protein
  • MUC1/ZD protein
  • PEM protein
  • PEMT protein
  • PUM protein

Protein level used designations for MUC1

DF3 antigen , H23 antigen , breast carcinoma-associated antigen DF3 , cancer antigen 15-3 , carcinoma-associated mucin , episialin , krebs von den Lungen-6 , mucin 1, transmembrane , mucin-1 , peanut-reactive urinary mucin , polymorphic epithelial mucin , tumor associated epithelial mucin , tumor-associated epithelial membrane antigen , tumor-associated mucin , endometrial mucin-1 , epithelial mucin , MUC-1 , Mucin1

GENE ID SPECIES
4582 Homo sapiens
448784 Canis lupus familiaris
397382 Sus scrofa
281333 Bos taurus
100009240 Oryctolagus cuniculus
24571 Rattus norvegicus
100733534 Cavia porcellus
17829 Mus musculus
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