Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MUC1 Protein (AA 890-1158) (His tag)

MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN6950993
  • Target See all MUC1 Proteins
    MUC1 (Mucin 1 (MUC1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 890-1158
    Origin
    • 27
    • 8
    • 3
    • 3
    • 2
    Human
    Source
    • 14
    • 13
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MUC1 protein is labelled with His tag.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product MUC1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    MUC1 (Mucin 1 (MUC1))
    Alternative Name
    Mucin-1 (MUC1 Products)
    Synonyms
    CA 15-3 Protein, CD227 Protein, EMA Protein, H23AG Protein, KL-6 Protein, MAM6 Protein, MCKD1 Protein, MUC-1 Protein, MUC-1/SEC Protein, MUC-1/X Protein, MUC1/ZD Protein, PEM Protein, PEMT Protein, PUM Protein, Muc-1 Protein, mucin 1, cell surface associated Protein, mucin 1, transmembrane Protein, MUC1 Protein, Muc1 Protein
    Background
    Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
    Molecular Weight
    21.3 kDa (partial α chain) & 8.4 kDa (partial β chain)
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
You are here:
Support