MUC1 Protein (AA 890-1158) (His tag)
Quick Overview for MUC1 Protein (AA 890-1158) (His tag) (ABIN6950993)
Target
See all MUC1 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 890-1158
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Purification tag / Conjugate
- This MUC1 protein is labelled with His tag.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Mucin 1 (MUC1) (AA 315-420) protein (GST tag)
MUC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Mucin 1 (MUC1) (AA 24-158) (Active) protein (hFc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Mucin 1 (MUC1) (AA 24-380) (Active) protein (Fc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Mucin 1 (MUC1) (AA 1036-1156) protein (Fc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ScA, ADA, AM
Mucin 1 (MUC1) (AA 1036-1156) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ScA, ADA, AM
Mucin 1 (MUC1) (AA 1036-1155) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- MUC1 (Mucin 1 (MUC1))
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Alternative Name
- Mucin-1
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Background
- Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
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Molecular Weight
- 21.3 kDa (partial α chain) & 8.4 kDa (partial β chain)
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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