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Mouse (Murine) IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2007346
Dinarello: Biologic basis for interleukin-1 in disease. in Blood 1996
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Human IL1A Protein expressed in Human Cells - ABIN2002135
Hogquist, Nett, Unanue, Chaplin: Interleukin 1 is processed and released during apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1991
Show all 5 references for ABIN2002135
Human IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2667487
Yatabe, Mochizuki, Takizawa, Chijiiwa, Okada, Kimura, Fujita, Matsumoto, Toyama, Okada: Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes. in Annals of the rheumatic diseases 2009
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Human IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2667482
Boraschi, Tagliabue: The interleukin-1 receptor family. in Vitamins and hormones 2006
Show all 3 references for ABIN2667482
Mouse (Murine) IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2667484
Son, Roby: Interleukin-1alpha-induced chemokines in mouse granulosa cells: impact on keratinocyte chemoattractant chemokine, a CXC subfamily. in Molecular endocrinology (Baltimore, Md.) 2006
Show all 3 references for ABIN2667484
Human IL1A Protein expressed in HEK-293 Cells - ABIN2181296
Bankers-Fulbright, Kalli, McKean: Interleukin-1 signal transduction. in Life sciences 1996
Show all 2 references for ABIN2181296
As a dual function cytokine, IL-1alpha may contribute to the induction of CHOP (show DDIT3 Proteins) intracellularly, while IL-1alpha released from necrotic cells accelerates steatohepatitis via induction of inflammatory cytokines by neighboring cells.
findings point to a prominent role of IL-1 signaling in the immune response to Trichophyton rubrum
These data demonstrate that DC and macrophages display distinct patterns of cytokine regulation, particularly with respect to IL-1, as a consequence of cell-type specific differences in the physicochemical properties of the P2X(7 (show P2RX7 Proteins))R
Data suggest the role of stromal cell IL-1alpha and IL-1beta (show IL1B Proteins) in Kawasaki disease vasculitis model.
IL-1alpha-positive cells were identified in the epithelium in dextran sulfate sodium (DSS (show PMP22 Proteins))-induced colitis. IL-1alpha was detected in the stool of colitic mice before IL-1beta (show IL1B Proteins).
Addition of anti-IL-1 Antibodies restored B lymphopoiesis in bone marrow cultures containing myeloid-derived suppressor cells, showing that myeloid-derived suppressor cell inhibition of B lymphopoiesis is mediated by IL-1.
The aim of this study was to characterize the role of IL-1 in cellular responses of carbon nanotubes in cells from IL-1alpha/beta wild type (IL1-WT) mice.
These findings do not support the previously suggested role of nuclear IL-1alpha in gene regulation of IL-1beta (show IL1B Proteins).
the underlying mechanism by which AR influences AAA (show AAAS Proteins) development is through IL-1alpha and transforming growth factor-beta1, and provides a potential new therapy to suppress/prevent AAA (show AAAS Proteins) by targeting AR with ASC (show STS Proteins)-J9.
inhibition of this potentially important source of chronic inflammation in atherosclerosis requires blockade of interleukin-1alpha and not interleukin-1beta.
significant differences were found in carriage rate of both minor alleles of IL-1A (C-889T) and IL-1B (C+3954T) polymorphisms of aggressive periodontitis (AgP) cases compared with healthy controls in the Algerian population; the polymorphisms of the IL-1 genes appear to be associated with susceptibility to AgP in the Algerian population
Suggest that IL-1alpha rs17561 polymorphism may not be associated with susceptibility to Tourette syndrome in Chinese Han population.
Letter: Knockdown of either filaggrin (show FLG Proteins) or loricrin (show LOR Proteins) increases the productions of interleukin (IL)-1alpha, IL-8 (show IL8 Proteins), IL-18 (show IL18 Proteins) and granulocyte macrophage colony-stimulating factor (show CSF2 Proteins) in stratified human keratinocytes.
No Alzheimer's disease relation with IL-1a C889T polymorphisms for this study.
The study investigates Il-1 gene cluster polymorphisms and their association with coronary artery disease. Significant differences in association statuses were seen for IL1A +4845 G>T, IL1B (show IL1B Proteins) -511 C>T.
the Ins (show INS Proteins)/Del polymorphism in the 3'UTR of IL1A may affect genetic expression; the minor allele (Del) is associated with an elevated risk for osteoarthritis and disease severity
Data show that the expressions of interleukins IL-1 and IL-6 (show IL6 Proteins) in the discs of discogenic low back pain (DLBP) patients were significantly elevated and negatively correlated with the Japanese Orthopedic Association (mJOA) scores of low back pain.
This study demonstrate a significant association of the IL-1A-889 functional polymorphism with Coronary Artery Disease.
Inactivation of the EGFR (show EGFR Proteins) with a blocking antibody decreased the S. aureus-mediated IL-1alpha induction in primary keratinocytes. Inflammasomes mediate induced secretion but not induced gene expression of IL-1alpha.
The aim of this study was to evaluate the effect of IL1A rs3783553 on CRC (show CALR Proteins) risk. CRC (show CALR Proteins) patients (N = 339) and healthy control subjects (N = 313)
Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes.
Testicular IL-1 alpha and IL-1 beta (show IL1B Proteins) concentrations were highest in the early post-natal period; however, IL-1 bioactivity and IL-6 (show IL6 Proteins) concentrations were greatest in the immediate pre-pubertal period.
Genes for IL-1alpha and IL-1beta (show IL1B Proteins) are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta (show IL1B Proteins) may have different roles as regulating PGF (show PGF Proteins)(2alpha) and PGE (show LIPF Proteins)(2) production during luteal phase.
non-metalloproteinase mechanisms participate in IL-1-induced matrix degradation and loss of tissue material properties
These results suggest that IL-1alpha and IL-1beta (show IL1B Proteins) are produced by the stromal cells, that IL-1beta (show IL1B Proteins) is produced by the epithelial cells, and that IL-1alpha is a more potent stimulator of prostaglandin and plasminogen (show PLG Proteins) activator in bovine endometrial cells.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
, interleukin-1 alpha
, preinterleukin 1 alpha
, interleukin 1-alpha
, Interleukin-1 alpha
, precursor interleukin-1alpha
, interleukin 1 alpha
, precursor interleukin 1 alpha