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Browse our IL1A Proteins (IL1A)

Full name:
Interleukin 1 alpha Proteins (IL1A)
On are 150 Interleukin 1 alpha (IL1A) Proteins from 21 different suppliers available. Additionally we are shipping IL1A Antibodies (433) and IL1A Kits (198) and many more products for this protein. A total of 801 IL1A products are currently listed.
Il-1, IL-1 alpha, IL-1A, IL-1alpha, IL1, IL1-ALPHA, IL1F1, L1A
list all proteins Gene Name GeneID UniProt
IL1A 111343  
IL1A 24493 P16598
IL1A 3552 P01583

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IL1A Proteins (IL1A) by Origin

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Top referenced IL1A Proteins

  1. Mouse (Murine) IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2007346 : Dinarello: Biologic basis for interleukin-1 in disease. in Blood 1996 (PubMed)
    Show all 6 references for ABIN2007346

  2. Human IL1A Protein expressed in Human Cells - ABIN2002135 : Hogquist, Nett, Unanue, Chaplin: Interleukin 1 is processed and released during apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for ABIN2002135

  3. Human IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2667487 : Yatabe, Mochizuki, Takizawa, Chijiiwa, Okada, Kimura, Fujita, Matsumoto, Toyama, Okada: Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes. in Annals of the rheumatic diseases 2009 (PubMed)
    Show all 4 references for ABIN2667487

  4. Human IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2667482 : Boraschi, Tagliabue: The interleukin-1 receptor family. in Vitamins and hormones 2006 (PubMed)
    Show all 3 references for ABIN2667482

  5. Mouse (Murine) IL1A Protein expressed in Escherichia coli (E. coli) - ABIN2667484 : Son, Roby: Interleukin-1alpha-induced chemokines in mouse granulosa cells: impact on keratinocyte chemoattractant chemokine, a CXC subfamily. in Molecular endocrinology (Baltimore, Md.) 2006 (PubMed)
    Show all 3 references for ABIN2667484

  6. Human IL1A Protein expressed in HEK-293 Cells - ABIN2181296 : Bankers-Fulbright, Kalli, McKean: Interleukin-1 signal transduction. in Life sciences 1996 (PubMed)
    Show all 2 references for ABIN2181296

More Proteins for IL1A Interaction Partners

Mouse (Murine) Interleukin 1 alpha (IL1A) interaction partners

  1. Il-1 signaling pathway has a key role in abdominal aortic aneurysm formation in mouse model of Kawasaki disease.

  2. endothelial cells were identified as the primary cellular source of G-CSF (show CSF3 Proteins) during OPC, which responded to IL-1alpha that was released from keratinocytes in the infected tissue.

  3. Studies indicate that SHP1 (show PTPN6 Proteins) and SYK (show SYK Proteins) crosstalk as a critical regulator of MyD88 (show MYD88 Proteins) post-translational modifications and IL-1-driven inflammation.

  4. We investigated the role of IL-1 signaling during MAV (show KLHL2 Proteins)-1-induced encephalitis. Unexpectedly, the lack of IL-1 signaling increased the mortality and inflammation in mice infected with MAV (show KLHL2 Proteins)-1.

  5. As a dual function cytokine, IL-1alpha may contribute to the induction of CHOP (show DDIT3 Proteins) intracellularly, while IL-1alpha released from necrotic cells accelerates steatohepatitis via induction of inflammatory cytokines by neighboring cells.

  6. findings point to a prominent role of IL-1 signaling in the immune response to Trichophyton rubrum

  7. These data demonstrate that DC and macrophages display distinct patterns of cytokine regulation, particularly with respect to IL-1, as a consequence of cell-type specific differences in the physicochemical properties of the P2X(7 (show P2RX7 Proteins))R

  8. Data suggest the role of stromal cell IL-1alpha and IL-1beta (show IL1B Proteins) in Kawasaki disease vasculitis model.

  9. IL-1alpha-positive cells were identified in the epithelium in dextran sulfate sodium (DSS (show PMP22 Proteins))-induced colitis. IL-1alpha was detected in the stool of colitic mice before IL-1beta (show IL1B Proteins).

  10. Addition of anti-IL-1 Antibodies restored B lymphopoiesis in bone marrow cultures containing myeloid-derived suppressor cells, showing that myeloid-derived suppressor cell inhibition of B lymphopoiesis is mediated by IL-1.

Human Interleukin 1 alpha (IL1A) interaction partners

  1. Studies indicate that interleukin (IL)-1beta (show IL1B Proteins), IL-1alpha, IL-33 (show IL33 Proteins) and high-mobility group box 1 (HMGB1 (show HMGB1 Proteins)) enter the extracellular space through mechanisms collectively known as unconventional secretion.

  2. This study demonstrates that the rs3783553 polymorphism may be involved in susceptibility to endometrial cancer. The II genotype seems to be a protective factor for endometrial cancer in Chinese Han women.

  3. Circulating Il1a levels were not altered in nonalcoholic fatty liver disease.

  4. this study shows that IL-1a gene variants are not associated with susceptibility to juvenile idiopathic arthritis in Iranian population

  5. IL1 and IL6 (show IL6 Proteins) are important components of the tumor microenvironment, displaying multiple functions. These cytokines take part at all stages of oncogenesis: from initiation to tumor, invasion, and metastasis of already established malignant and mutant epithelial cells. [Review]

  6. Genetic polymorphisms in the IL1A, IL1B (show IL1B Proteins), IL2 (show IL2 Proteins) and IL6 (show IL6 Proteins) genes are not genetic modulators of depression in a cohort of Polish subjects.

  7. functional polymorphism rs3783553 in IL-1A could contribute to gastric cancer susceptibility, possibly or at least partially through affecting the transcriptional activity of IL-1A.

  8. The prevalence of the CT genotype of IL1A rs17561 polymorphism was increased in preeclamptic women compared with controls.

  9. IL-1A rs17561 and IL-1B (show IL1B Proteins) rs1143634 polymorphisms are associated with periodontitis.

  10. A functional insertion/deletion polymorphism in the IL1A gene is associated with decreased risk of breast cancer.

Pig (Porcine) Interleukin 1 alpha (IL1A) interaction partners

Rabbit Interleukin 1 alpha (IL1A) interaction partners

Cow (Bovine) Interleukin 1 alpha (IL1A) interaction partners

  1. Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes.

  2. Testicular IL-1 alpha and IL-1 beta (show IL1B Proteins) concentrations were highest in the early post-natal period; however, IL-1 bioactivity and IL-6 (show IL6 Proteins) concentrations were greatest in the immediate pre-pubertal period.

  3. Genes for IL-1alpha and IL-1beta (show IL1B Proteins) are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta (show IL1B Proteins) may have different roles as regulating PGF (show PGF Proteins)(2alpha) and PGE (show LIPF Proteins)(2) production during luteal phase.

  4. non-metalloproteinase mechanisms participate in IL-1-induced matrix degradation and loss of tissue material properties

  5. These results suggest that IL-1alpha and IL-1beta (show IL1B Proteins) are produced by the stromal cells, that IL-1beta (show IL1B Proteins) is produced by the epithelial cells, and that IL-1alpha is a more potent stimulator of prostaglandin and plasminogen (show PLG Proteins) activator in bovine endometrial cells.

IL1A Protein Profile

Protein Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Alternative names and synonyms associated with IL1A

  • interleukin 1 complex (Il1)
  • interleukin 1 alpha (Il1a)
  • interleukin 1, alpha (IL1A)
  • interleukin 1, alpha (Il1a)
  • Il-1 protein
  • IL-1 alpha protein
  • IL-1A protein
  • IL-1alpha protein
  • IL1 protein
  • IL1-ALPHA protein
  • IL1F1 protein
  • L1A protein

Protein level used designations for Interleukin 1 alpha Proteins (IL1A)

IL-1 alpha , interleukin-1 alpha , hematopoietin-1 , preinterleukin 1 alpha , pro-interleukin-1-alpha , interleukin 1-alpha , Interleukin-1 alpha , precursor interleukin-1alpha , interleukin 1 alpha , precursor interleukin 1 alpha

111343 Mus musculus
16175 Mus musculus
24493 Rattus norvegicus
3552 Homo sapiens
397094 Sus scrofa
403782 Canis lupus familiaris
100861289 Capra hircus
100009250 Oryctolagus cuniculus
281250 Bos taurus
493944 Felis catus
100135555 Cavia porcellus
100064969 Equus caballus
443404 Ovis aries
700193 Macaca mulatta
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