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IL1A Protein (AA 113-271) (His tag)

IL1A Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274874
  • Target See all IL1A Proteins
    IL1A (Interleukin 1 alpha (IL1A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 113-271
    Origin
    • 18
    • 12
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    Source
    • 39
    • 13
    • 11
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL1A protein is labelled with His tag.
    Purpose
    Cynomolgus IL-1 alpha/IL-1A Protein
    Sequence
    Ser113-Ala271
    Characteristics
    Recombinant Cynomolgus IL-1 alpha/IL-1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser113-Ala271.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product IL1A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL1A (Interleukin 1 alpha (IL1A))
    Alternative Name
    IL-1 alpha (IL1A Products)
    Synonyms
    IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein
    Background
    The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
    Molecular Weight
    19.23 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
    UniProt
    P79340
    Pathways
    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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