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Browse our anti-Insulin Receptor (INSR) Antibodies

Full name:
anti-Insulin Receptor Antibodies (INSR)
On are 314 Insulin Receptor (INSR) Antibodies from 29 different suppliers available. Additionally we are shipping Insulin Receptor Kits (35) and Insulin Receptor Proteins (34) and many more products for this protein. A total of 409 Insulin Receptor products are currently listed.
18402, 4932439J01Rik, cd220, CG18402, CTK-1, D630014A15Rik, DIHR, DILR, dinr, dInsR, dir, Dir-a, Dir-b, DIRbeta, dIRH, Dmel\\CG18402, er10, hhf5, inr, Inr-alpha, Inr-beta, INS, INSR, insulin/insulin-like growth factor receptor, ir, ir-A, IR-B, l(3)05545, l(3)93Dj, l(3)er10, lnR, NV14476
list all antibodies Gene Name GeneID UniProt
INSR 3643 P06213
INSR 16337 P15208
INSR 24954  

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Most Popular Reactivities for anti-Insulin Receptor (INSR) Antibodies

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anti-Human Insulin Receptor Antibodies:

anti-Mouse (Murine) Insulin Receptor Antibodies:

anti-Rat (Rattus) Insulin Receptor Antibodies:

All available anti-Insulin Receptor Antibodies

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Top referenced anti-Insulin Receptor Antibodies

  1. Human Monoclonal Insulin Receptor Primary Antibody for Func, IP - ABIN1106089 : Soos, Siddle, Baron, Heward, Luzio, Bellatin, Lennox: Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor. in The Biochemical journal 1986 (PubMed)
    Show all 6 references for ABIN1106089

  2. Mouse (Murine) Monoclonal Insulin Receptor Primary Antibody for IF, IP - ABIN967752 : Ebina, Ellis, Jarnagin, Edery, Graf, Clauser, Ou, Masiarz, Kan, Goldfine: The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. in Cell 1985 (PubMed)
    Show all 5 references for ABIN967752

  3. Human Polyclonal Insulin Receptor Primary Antibody for EIA - ABIN358482 : Nakamaru, Matsumoto, Taguchi, Suefuji, Murata, Igata, Kawashima, Kondo, Motoshima, Tsuruzoe, Miyamura, Toyonaga, Araki: AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells. in Biochemical and biophysical research communications 2005 (PubMed)
    Show all 5 references for ABIN358482

  4. Human Polyclonal Insulin Receptor Primary Antibody for EIA, IHC (p) - ABIN359886 : George, Johansen, Soos, Mortensen, Gammeltoft, Saudek, Siddle, Hansen, ORahilly: Deletion of V335 from the L2 domain of the insulin receptor results in a conformationally abnormal receptor that is unable to bind insulin and causes Donohue's syndrome in a human subject. in Endocrinology 2003 (PubMed)
    Show all 5 references for ABIN359886

  5. Human Polyclonal Insulin Receptor Primary Antibody for IF (p), IHC (p) - ABIN671841 : Bai, Chen, Liu, Tian, Zhou, Liu, Fang, Chen: Effects of water extract and crude polysaccharides from Liriope spicata var. prolifera on InsR/IRS-1/PI3K pathway and glucose metabolism in mice. in Journal of ethnopharmacology 2009 (PubMed)
    Show all 2 references for ABIN671841

  6. Human Polyclonal Insulin Receptor Primary Antibody for WB - ABIN1881461 : Pandini, Frasca, Mineo, Sciacca, Vigneri, Belfiore: Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN1881461

  7. Dog (Canine) Polyclonal Insulin Receptor Primary Antibody for IHC, WB - ABIN2792204 : Netzer, Freudenberg, Heinze, Heinze-Kuhn, Goebel, McCarthy, Roses, Göbel, Todt, Kubisch: Replication study of the insulin receptor gene in migraine with aura. in Genomics 2008 (PubMed)

  8. Dog (Canine) Polyclonal Insulin Receptor Primary Antibody for IHC (p), WB - ABIN1106088 : Taira, Taira, Hashimoto, Shimada, Suzuki, Kanatsuka, Nakamura, Ebina, Tatibana, Makino: Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor. in Science (New York, N.Y.) 1989 (PubMed)

More Antibodies against Insulin Receptor Interaction Partners

Fruit Fly (Drosophila melanogaster) Insulin Receptor (INSR) interaction partners

  1. Results show that lifespan and behavioral senescence are independently regulated by the Drosophila insulin receptor.

  2. Study shows that the increase in the dopamine level in D. melanogaster females with the InR gene knockdown in corpus allatum ensures their increased resistance to starvation-induced stress

  3. results indicate that the Drosophila insulin-like peptide system is a crucial regulator of sleep

  4. This study has shown for the first time that suppression of InR expression in VNC leads to a rise in the survival of flies under conditions of toxic stress.

  5. The combined activities of Stit and InR in ectodermal epithelial tissues provide an RTK-mediated, two-tiered reaction threshold to varying nutritional conditions that promote epithelial organ growth even at low levels of InR signaling.

  6. InR, but not Tor, signaling non-autonomously promotes primordial germ cell differentiation.

  7. Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling.

  8. Mutations in the D. melanogaster Insulin Receptor (InR) alter SGP cell number but not ovarian morphogenesis

  9. Concerted control of gliogenesis by InR/TOR and FGF signalling in the Drosophila post-embryonic brain

  10. The phospholipase C (show PLC Antibodies)-gamma (PLC (show PLC Antibodies)-gamma) encoded by small wing (sl) acts as such a link between growth and patterning/differentiation by modulating some MAPK (show MAPK1 Antibodies) outputs once activated by the insulin (show INS Antibodies) pathway.

Human Insulin Receptor (INSR) interaction partners

  1. Mutations of the INSR gene is associated with acanthosis nigricans and hyperandrogenism.

  2. Identification of a Novel Homozygous INSR Variant in a Patient with Rabson-Mendenhall Syndrome from the United Arab Emirates.

  3. Findings suggest that insulin receptor substrate -1 (show IRS1 Antibodies) Gly972Arg polymorphism is associated with polycystic ovary syndrome in the Caucasian ethnicity, and insulin receptor substrate -2 (show IRS2 Antibodies) Gly1057Asp polymorphism is correlated with polycystic ovary syndrome in the Asian ethnicity. However, insulin receptor His 1058 C/T polymorphism may not be implicated in polycystic ovary syndrome.

  4. Two miR (show MLXIP Antibodies)-binding SNPs SLC30A8 (show SLC30A8 Antibodies) rs2466293 and INSR rs1366600 increased Gestational diabetes mellitus susceptibility. Functional studies were required to confirm the underlying mechanism.

  5. The data demonstrate that insulin (show INS Antibodies), IGF1 (show IGF1 Antibodies) and IGF2 elicit different insulin receptor phosphorylation kinetics and potencies that translate to downstream signaling.

  6. Suggest a novel role of miR (show MLXIP Antibodies)-503 as a regulator of vascular smooth muscle cell proliferation and migration by modulating INSR.

  7. In silico characterization of nsSNPs affecting INSR gene function can aid in better understanding of genetic differences in disease susceptibility.

  8. The INSR gene is potentially associated with eating difficulties in preterm infants.

  9. Study describes a revised structure of the human insulin receptor ectodomain revealing new features within the receptor insert domain and corrects errors in the first and third fibronectin (show FN1 Antibodies) type III domains. The new structure allows improved resolution of the insert domain, a critical element to ligand binding and signal transduction.

  10. C1008T SNP at exon 17 of INSR is associated with insulin (show INS Antibodies) resistance in Indian women with polycystic ovarian syndrome.

Mouse (Murine) Insulin Receptor (INSR) interaction partners

  1. Suggest that overexpression of IGF-IR or IRA isoform, as homodimers or as part of IRA/IGF-IR hybrid receptors, confers a stronger migratory capability to vascular smooth muscle cells and might occur in early stages of atherosclerotic process.

  2. Acute knockdown of Insr or both Irs1 (show IRS1 Antibodies) and Irs2 (show IRS2 Antibodies) in adipocytes increased Adipoq (show ADIPOQ Antibodies) mRNA expression but reduced adiponectin (show ADIPOQ Antibodies) secretion.

  3. unsuppressed lipolysis in adipocytes elicited by HFD feeding is linked with enhanced gluconeogenesis from glycerol and with alterations in BA physiology in Insr(P1195L/+)/HFD liver.

  4. NF-kappaB (show NFKB1 Antibodies)-miR (show MLXIP Antibodies)-195/497-Igf1r (show IGF1R Antibodies)/Insr-Ccnd2 (show CCND2 Antibodies)/Ccne1 (show CCNE1 Antibodies) plays important roles in myogenesis.

  5. Therefore, overexpression of insulin receptor improves obese and diabetic phenotypes in db/db (show LEPR Antibodies) mice, with consequences on growth.

  6. only Ptprj (show PTPRJ Antibodies) was co-expressed with the IR in major insulin (show INS Antibodies) target tissues : the skeletal muscle, liver and adipose tissue. the activation of IR and Akt (show AKT1 Antibodies) by insulin (show INS Antibodies) was enhanced, and glucose and insulin (show INS Antibodies) tolerance was improved in Ptprj (show PTPRJ Antibodies)-deficient mice

  7. the insulin (show INS Antibodies)-InsR signaling drives multipotent progenitors differentiation into lymphoid lineages in early lymphopoiesis.

  8. Data reports that IRA in beta cells confers a stronger proliferation capability favoring the mitogenic effects of IGF-I (show IGF1 Antibodies) and also increasing glucose uptake of these cells, a key factor in pancreatic beta cell proliferation.

  9. Our results indicate that the insulin receptor may have some role in controlling the rate of rod response decay, but they exclude a major role of the insulin receptor pathway in phototransduction.

  10. Mutation in the insulin receptor attenuated the oxidative stress and apoptosis in beta-cells.

Cow (Bovine) Insulin Receptor (INSR) interaction partners

  1. studied by RT reverse-transcription PCR, whether there are differences in the abundance of mRNA coding for IGF-I (show IGF1 Antibodies), IGF-2, IGFBP-2 (show IGFBP2 Antibodies), IGFBP-3 (show IGFBP3 Antibodies), IGF-1R (show IGF1R Antibodies), IGF-2R, GHR (show GHR Antibodies), and InsR in compartmentalized layers of jejunum and ileum of 5-d-old calves fed colostrum

  2. insulin receptor and phosphoinositide 3-kinase localize to detergent-resistant membrane rafts of rod photoreceptor outer segments

  3. FSH (show BRD2 Antibodies), but not E2, stimulated the expression of IR and GHR (show GHR Antibodies) genes during follicular development.

  4. Data conclude that insulin (show INS Antibodies) and IGF-I (show IGF1 Antibodies) receptors differentially mediate the production of adhesion molecules by ECs and monocyte adhesion onto the vascular endothelium in response to the hyperinsulinemic state.

Insulin Receptor (INSR) Antigen Profile

Antigen Summary

After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Insulin Receptor (INSR)

  • Insulin-like receptor (InR) antibody
  • insulin receptor (INSR) antibody
  • insulin receptor (Insr) antibody
  • insulin receptor (insr) antibody
  • insulin receptor precursor (DAF-2) antibody
  • 18402 antibody
  • 4932439J01Rik antibody
  • cd220 antibody
  • CG18402 antibody
  • CTK-1 antibody
  • D630014A15Rik antibody
  • DIHR antibody
  • DILR antibody
  • dinr antibody
  • dInsR antibody
  • dir antibody
  • Dir-a antibody
  • Dir-b antibody
  • DIRbeta antibody
  • dIRH antibody
  • Dmel\\CG18402 antibody
  • er10 antibody
  • hhf5 antibody
  • inr antibody
  • Inr-alpha antibody
  • Inr-beta antibody
  • INS antibody
  • INSR antibody
  • insulin/insulin-like growth factor receptor antibody
  • ir antibody
  • ir-A antibody
  • IR-B antibody
  • l(3)05545 antibody
  • l(3)93Dj antibody
  • l(3)er10 antibody
  • lnR antibody
  • NV14476 antibody

Protein level used designations for anti-Insulin Receptor (INSR) Antibodies

CG18402-PA , CG18402-PB , CG18402-PC , CG18402-PD , InR-PA , InR-PB , InR-PC , InR-PD , drosophila insulin receptor , insulin , insulin receptor , insulin receptor homolog , insulin receptor homologue , insulin-like receptor , insulin-receptor , lethal(3)93Dj , insulin receptor-like , IR , XTK-1b , insulin receptor, beta-subunit , xe-InsR , insulin receptor tyrosine kinase , tyrosine kinase

42549 Drosophila melanogaster
455649 Pan troglodytes
455650 Pan troglodytes
100027215 Monodelphis domestica
100066248 Equus caballus
100122567 Nasonia vitripennis
100126753 Papio anubis
100127108 Felis catus
100403400 Callithrix jacchus
100451802 Pongo abelii
100473956 Ailuropoda melanoleuca
3643 Homo sapiens
16337 Mus musculus
396755 Sus scrofa
408017 Bos taurus
443431 Ovis aries
100141504 Oryctolagus cuniculus
24954 Rattus norvegicus
398006 Xenopus laevis
484990 Canis lupus familiaris
420133 Gallus gallus
100718484 Cavia porcellus
706009 Macaca mulatta
100008911 Oryctolagus cuniculus
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