Browse our Thioredoxin Domain Containing 3 (Spermatozoa) Proteins (TXNDC3)

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Thioredoxin Domain Containing 3 (Spermatozoa) Proteins (TXNDC3)
On are 4 Thioredoxin Domain Containing 3 (Spermatozoa) (TXNDC3) Proteins from 3 different suppliers available. Additionally we are shipping Thioredoxin Domain Containing 3 (Spermatozoa) Antibodies (32) and many more products for this protein. A total of 42 Thioredoxin Domain Containing 3 (Spermatozoa) products are currently listed.
1700056P15Rik, CILD6, NM23-H8, Sptrx-2, Sptrx2, Txndc3
list all proteins Gene Name GeneID UniProt
TXNDC3 51314 Q8N427
Mouse TXNDC3 TXNDC3 73412 Q715T0
Rat TXNDC3 TXNDC3 364729  

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Thioredoxin Domain Containing 3 (Spermatozoa) Proteins (TXNDC3) by Origin

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More Proteins for Thioredoxin Domain Containing 3 (Spermatozoa) Interaction Partners

Human Thioredoxin Domain Containing 3 (Spermatozoa) (TXNDC3) interaction partners

  1. Addition of the minor allele for rs670139 (MS4A4E), rs9331896 (CLU (show CLU Proteins)), and rs12155159 (NME8) was nominally associated with change on the DWRT, DSST, and WFT, respectively, in whites.

  2. NME8 locus polymorphism is associated with cognitive decline, cerebrospinal fluid and neuroimaging biomarkers in Alzheimer's disease.

  3. GPR141 (show GPR141 Proteins)-NME8 locus had strong genetic effect on the susceptibility to generalized periodontitis in Japanese individuals with history of smoking. identified 2 suggestive loci for periodontitis in a Japanese population.

  4. Our approach yielded 26 candidate genes differentially expressed between patients (Osteoarthritis) and controls. The presence of allelic imbalances confirms cis (show CISH Proteins)-regulatory mechanisms for RHOB and TXNDC3.

  5. genetic association of RHOB and TXNDC3 with osteoarthritis was detected

  6. Primary ciliary dyskinesia is caused by an SNP-induced modification of the ratio of two physiological isoforms of TXNDC3 generated by alternative splicing.

  7. The minor allele frequencies of TXNDC3 in East Asian individuals are significantly different from those in United Kingdom control individuals.

Mouse (Murine) Thioredoxin Domain Containing 3 (Spermatozoa) (TXNDC3) interaction partners

  1. Txndc2 (show TXNDC2 Proteins) and Txndc3 are critically important in protecting spermatozoa against the increases in oxidative stress associated with paternal age.

  2. data indicate that spermatid-specific thioredoxin-2 incorporation into the sperm fibrous sheath(FS) lags well behind FS assembly, suggesting it is required during the final stages of sperm tail maturation

Thioredoxin Domain Containing 3 (Spermatozoa) (TXNDC3) Protein Profile

Protein Summary

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

Alternative names and synonyms associated with Thioredoxin Domain Containing 3 (Spermatozoa) (TXNDC3)

  • NME/NM23 family member 8 (NME8)
  • NME/NM23 family member 8 (Nme8)
  • 1700056P15Rik protein
  • CILD6 protein
  • NM23-H8 protein
  • Sptrx-2 protein
  • Sptrx2 protein
  • Txndc3 protein

Protein level used designations for TXNDC3

sperm-specific thioredoxin 2 , spermatid-specific thioredoxin-2 , thioredoxin domain containing 3 (spermatozoa) , thioredoxin domain-containing protein 3 , spermatid-specific thioredoxin-2 protein , sptrx-2

51314 Homo sapiens
73412 Mus musculus
364729 Rattus norvegicus
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