Browse our anti-ATM (ATM) Antibodies

Full name:
anti-Ataxia Telangiectasia Mutated Antibodies (ATM)
On www.antibodies-online.com are 355 Ataxia Telangiectasia Mutated (ATM) Antibodies from 33 different suppliers available. Additionally we are shipping ATM Kits (46) and ATM Proteins (5) and many more products for this protein. A total of 420 ATM products are currently listed.
Synonyms:
AI256621, AT1, ATA, ATC, ATD, ATDC, ATE, atm, atm/tefu, C030026E19Rik, CG6535, dATM, Dmel\\CG6535, tef, Tefu, TEL1, TELO1, Xatm
list all antibodies Gene Name GeneID UniProt
ATM 472 Q13315
ATM 300711  
ATM 11920 Q62388

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Top referenced anti-ATM Antibodies

  1. Human Monoclonal ATM Primary Antibody for ChIP, ELISA - ABIN151775 : Naka, Tachibana, Ikeda, Motoyama: Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts. in The Journal of biological chemistry 2004 (PubMed)
    Show all 114 references for 151775

  2. Human Polyclonal ATM Primary Antibody for ICC, FACS - ABIN151030 : Out, Hoekstra, de Jager, de Vos, van der Westhuyzen, Webb, Van Eck, Biessen, Van Berkel: Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice. in Journal of lipid research 2005 (PubMed)
    Show all 76 references for 151030

  3. Human Monoclonal ATM Primary Antibody for ICC, IF - ABIN151772 : Yalcin, Zhang, Luciano, Mungamuri, Marinkovic, Vercherat, Sarkar, Grisotto, Taneja, Ghaffari: Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 19 references for 151772

  4. Human Polyclonal ATM Primary Antibody for IHC (p) - ABIN196822 : Gupta, Sharma, Young, Agarwal, Smith, Paull, Lucchesi, Khanna, Ludwig, Pandita: Involvement of human MOF in ATM function. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 references for 196822

  5. Human Polyclonal ATM Primary Antibody for IF, WB - ABIN319313 : Bernstein, Seminara, Børresen-Dale: Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002. in Breast cancer research : BCR 2002 (PubMed)
    Show all 4 references for 319313

  6. Human Polyclonal ATM Primary Antibody for IP, PLA - ABIN151739 : Kirshner, Jobling, Pajares, Ravani, Glick, Lavin, Koslov, Shiloh, Barcellos-Hoff: Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. in Cancer research 2006 (PubMed)
    Show all 4 references for 151739

  7. Human Monoclonal ATM Primary Antibody for WB - ABIN1449283 : Canman, Lim, Cimprich, Taya, Tamai, Sakaguchi, Appella, Kastan, Siliciano: Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 3 references for 1449283

  8. Human Monoclonal ATM Primary Antibody for ICC, IF - ABIN2668604 : Shrivastav, Miller, De Haro, Durant, Chen, Chen, Nickoloff: DNA-PKcs and ATM co-regulate DNA double-strand break repair. in DNA repair 2009 (PubMed)
    Show all 3 references for 2668604

  9. Human Polyclonal ATM Primary Antibody for DB, IF - ABIN389888 : Brunet, Gutiérrez-Enríquez, Torres, Bérez, Sanjosé, Galceran, Izquierdo, Menéndez, Gumà, Borràs: ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations. in Clinical genetics 2008 (PubMed)
    Show all 2 references for 389888

  10. Human Polyclonal ATM Primary Antibody for EIA - ABIN358435 : Tsai, Chung, Takahashi, Xu, Hu: Functional interaction between FOXO3a and ATM regulates DNA damage response. in Nature cell biology 2008 (PubMed)
    Show all 2 references for 358435

More Antibodies against ATM Interaction Partners

Fruit Fly (Drosophila melanogaster) Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. our data indicate that ATR and ATM are both needed for intestinal stem cell maintenance and proliferation; ATR seems to play a bigger role than does ATM.

  2. TCTP (show TPT1 Antibodies) has a role in regulating ATM activity to control genome stability and organ development in Drosophila melanogaster

  3. A stringent requirement for the conserved function of Ataxia Telangiectasia Mutated (ATM) in telomere protection during early embryonic development, is identified.

  4. ATM is primarily required for the meiotic DSB repair response, which includes functions in DNA damage repair and negative feedback control over the level of programmed DSBs during meiosis.

  5. Molecular genetic characterization of Drosophila ATM conserved functional domains.

  6. ATM checkpoint kinase (show ATR Antibodies) plays a role in telomere maintenance that is independent of telomerase regulation.

  7. Drosophila ATM and Mre11 (show MRE11A Antibodies) are essential for the G2/M checkpoint induced by low-dose irradiation.

  8. Results suggest that ATM and ATR protect telomere integrity by safeguarding chromatin architecture that favors the loading of telomere-elongating, capping, and silencing proteins.

Xenopus laevis Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. Dna2 (show DNA2 Antibodies) co-localizes in foci with RPA (show RPA1 Antibodies) and is found in a complex with replication fork components And-1 and Mcm10 (show MCM10 Antibodies). Dna2 (show DNA2 Antibodies) interacts with the DSB repair and checkpoint proteins Nbs1 (show NLRP2 Antibodies) and ATM.

  2. ATM and ATR (show ATR Antibodies) prevent accumulation of chromosomal abnormalities by promoting Mre11 (show MRE11A Antibodies)/Rad50 (show RAD50 Antibodies)/Nbs1 (show NLRP2 Antibodies) dependent recovery of collapsed replication forks.

  3. ATM and ATR (show ATR Antibodies) phosphorylate the functionally critical replication protein Mcm2 (show MCM2 Antibodies) during both DNA damage and replication checkpoint responses in Xenopus egg extracts

  4. PP2A counteracts ATM and ATR in a DNA damage checkpoint in Xenopus egg extracts

  5. Data show that ATM (ataxia-telangiectasia mutated) regulates Xenopus TopBP1 (show TOPBP1 Antibodies) by phosphorylating serine 1131 and thereby strongly enhancing association of TopBP1 (show TOPBP1 Antibodies) with ATR (show ATR Antibodies)(ATM and Rad3-related).

  6. ATM and ATR (show ATR Antibodies) control mitotic events in vertebrate cells by targeting CEP63 (show CEP63 Antibodies) and centrosome dependent spindle assembly.

  7. These findings suggest that the MRN complex is a crucial mediator in the process whereby ATM promotes the TopBP1 (show TOPBP1 Antibodies)-dependent activation of ATR (show ATR Antibodies)-ATRIP (show ATRIP Antibodies) in response to double-stranded DNA breaks.

  8. The Fanconi anemia protein (show FANCF Antibodies) FANCM (show FANCM Antibodies) is controlled by FANCD2 (show FANCD2 Antibodies) and the ATR (show ATR Antibodies)/ATM pathways.

Zebrafish Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. molecular cloning of the coding sequence of the catalytic domain of the zebrafish homologue of ATM

  2. Characterization of ataxia (show USP14 PLURAL_@14456@) telangiectasia protein.

Human Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. We report that endogenous huntingtin (show HTT Antibodies) protein directly participates in oxidative DNA damage repair. Using novel chromobodies to detect endogenous human huntingtin (show HTT Antibodies) in live cells, we show that localization of huntingtin (show HTT Antibodies) to DNA damage sites is dependent on the kinase activity of ataxia telangiectasia mutated (ATM) protein.

  2. The study showed a significant association between the ATM rs1801516 Asn allele and increased risk of radiation-induced normal tissue toxicity.

  3. In this paper, we describe an extension to the BOADICEA model to incorporate the effects of intermediate risk variants for breast cancer, specifically loss of function mutations in the three genes for which the evidence for association is clearest and the risk estimates most precise: PALB2 (show PALB2 Antibodies), CHEK2 (show CHEK2 Antibodies) and ATM

  4. Taken together, the findings suggest that a protein-protein interaction between ATM and p400 (show EP400 Antibodies) ATPase (show DNAH8 Antibodies) occurs independently of DNA damage and contributes to efficient DNA damage response and repair.

  5. following reprogramming the early and late replicating genome is differentially affected by copy number variations in ATM-deficient induced pluripotent stem cells (iPSCs) relative to wild-type iPSCs.

  6. ATM mutation is associated with ataxia (show USP14 PLURAL_@14456@)-telangiectasia.

  7. Results provide evidence that ATM along with 53BP1 (show TP53BP1 Antibodies) is involved in breast cancer cells resistance for PARP (show COL11A2 Antibodies) inhibitor; its deficiency causes resistance in 53BP1 (show TP53BP1 Antibodies)-depleted tumor cells.

  8. WRNIP1 (show WRNIP1 Antibodies) connects PCNA (show PCNA Antibodies) monoubiquitination with ATMIN (show ATMIN Antibodies)/ATM to activate ATM signalling in response to replication stress and contribute to the maintenance of genomic stability.

  9. Mutant IDH1 (show IDH1 Antibodies) downregulates the DNA damage (DD) sensor ATM by altering histone methylation, leading to impaired DNA repair, increased sensitivity to DD, and reduced HSC (show FUT1 Antibodies) self-renewal, independent of TET2 (show TET2 Antibodies).

  10. ATM rs189037 polymorphism is associated with reduced risk of T2DM

Pig (Porcine) Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. Ataxia (show USP14 PLURAL_@14456@) telangiectasia (AT) is a progressive multisystem disorder caused by mutations in the AT-mutated (ATM) gene. We engineered a novel porcine model of AT

  2. ATM influenced the meiotic and cytoplasmic maturation of porcine oocytes.

  3. ATM plays critical role in arsenite induced G2/M phase arrest in aortic endothelial cells possibly via regulation of checkpoint signaling molecules.

Cow (Bovine) Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. radiation-induced eNOS (show NOS3 Antibodies) activation in bovine aortic endothelial cells is regulated by ATM and HSP90 (show HSP90 Antibodies)

Mouse (Murine) Ataxia Telangiectasia Mutated (ATM) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (show TRAF1 Antibodies)/NF-kappaB (show NFKB1 Antibodies)-regulated apoptosis and the p53 (show TP53 Antibodies)/PCNA (show PCNA Antibodies)- and ATM/ATR (show ATR Antibodies)-Chk1 (show CHEK1 Antibodies)/2-controlled DNA-damage response pathways.

  2. this study shows that Atm-/- mice are more susceptible to pulmonary Streptococcus pneumoniae infection in a manner consistent with inflammasome defects

  3. This study show that like ataxia (show USP14 Antibodies) telangiectasia cells, ISG15 (show ISG15 Antibodies) is elevated in Atm-deficient mouse cerebellums.

  4. This study identifies attenuation of type I interferon (show IFNA Antibodies) responses as the primary mechanism underlying proviral function of ATM during gammaherpesvirus infection.

  5. Mutant IDH1 (show IDH1 Antibodies) downregulates the DNA damage (DD) sensor ATM by altering histone methylation, leading to impaired DNA repair, increased sensitivity to DD, and reduced HSC (show FUT1 Antibodies) self-renewal, independent of TET2 (show TET2 Antibodies).

  6. USP7 (show USP7 Antibodies) inhibition is selectively cytotoxic to CLL cells independently of ATM and p53 (show TP53 Antibodies) and synergizes with chemotherapy.

  7. Fractionated exposure to low doses of X-rays resulted in accumulation of DNA damage in the murine spleen and induction of apoptotic response in p53 (show TP53 Antibodies)/Atm-independent manner. Further studies are needed to understand the outcomes and molecular mechanisms underlying cellular responses and early induction of p38 (show CRK Antibodies) in response to prolonged exposure to IR.

  8. ATM, ATR (show ATR Antibodies) and DNA-PKcs (show PRKDC Antibodies) have unique and essential roles during the DNA damage response in the nervous system.

  9. TRAF6 (show TRAF6 Antibodies) and H2AX (show H2AFX Antibodies) overexpression and gammaH2AX (show H2AFX Antibodies)-mediated HIF1alpha (show HIF1A Antibodies) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (show HIF1A Antibodies)-driven tumorigenesis, glycolysis and metastasis.

  10. These results reveal a new requirement for ATMIN (show ATMIN Antibodies)-dependent ATM signaling in TP53 (show TP53 Antibodies)-deficient glioblastoma multiforme, indicating a pro-tumorigenic role for ATM in the context of these tumors.

ATM Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates\; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Alternative names and synonyms associated with ATM

  • telomere fusion (tefu) antibody
  • ataxia telangiectasia mutated (atm) antibody
  • ataxia telangiectasia mutated (ATM) antibody
  • ataxia telangiectasia mutated (EDI_100660) antibody
  • ataxia telangiectasia mutated (CpipJ_CPIJ001772) antibody
  • ataxia telangiectasia mutated (BDBG_08252) antibody
  • ataxia telangiectasia mutated (PAAG_02532) antibody
  • ataxia telangiectasia mutated (MCYG_05088) antibody
  • ataxia telangiectasia mutated (VDBG_06833) antibody
  • ataxia telangiectasia mutated (atm) (ACLA_015700) antibody
  • ataxia telangiectasia mutated (atm) (AaeL_AAEL014900) antibody
  • ataxia telangiectasia mutated (MGYG_07634) antibody
  • ataxia telangiectasia mutated (PGTG_14279) antibody
  • ataxia telangiectasia mutated (Atm) antibody
  • ataxia telangiectasia mutated (LOC100349299) antibody
  • ataxia telangiectasia mutated homolog (human) (Atm) antibody
  • AI256621 antibody
  • AT1 antibody
  • ATA antibody
  • ATC antibody
  • ATD antibody
  • ATDC antibody
  • ATE antibody
  • atm antibody
  • atm/tefu antibody
  • C030026E19Rik antibody
  • CG6535 antibody
  • dATM antibody
  • Dmel\\CG6535 antibody
  • tef antibody
  • Tefu antibody
  • TEL1 antibody
  • TELO1 antibody
  • Xatm antibody

Protein level used designations for ATM

CG6535-PB , ataxia telangiectasia mutated , ataxia telengiesctasia mutated , ataxia-telangiectasia mutated , drosophila ATM , tefu-PB , chunp9624 , ataxia telangiectasia mutated (includes complementation groups A, C and D) , ataxia telangiectasia mutated protein , serine-protein kinase ATM-like , ataxia telangiectasia mutated (atm) , A-T mutated , AT mutated , TEL1, telomere maintenance 1, homolog , serine-protein kinase ATM , Ataxia telangiectasia gene mutated in human beings , ataxia telangiectasia mutated homolog , A-T mutated homolog , ATM (ataxia telangiectasia mutated) , ataxia telangiectasia gene mutated in human beings

GENE ID SPECIES
41839 Drosophila melanogaster
398148 Xenopus laevis
403064 Danio rerio
451530 Pan troglodytes
577188 Strongylocentrotus purpuratus
5882524 Entamoeba dispar SAW760
6032926 Culex quinquefasciatus
8501759 Ajellomyces dermatitidis SLH14081
9099145 Paracoccidioides sp. 'lutzii' Pb01
9230975 Arthroderma otae CBS 113480
9537397 Verticillium alfalfae VaMs.102
100026797 Monodelphis domestica
100061765 Equus caballus
100217707 Taeniopygia guttata
100427400 Macaca mulatta
100451505 Pongo abelii
100480638 Ailuropoda melanoleuca
4706457 Aspergillus clavatus NRRL 1
5565620 Aedes aegypti
10025630 Arthroderma gypseum CBS 118893
10535503 Puccinia graminis f. sp. tritici CRL 75-36-700-3
472 Homo sapiens
300711 Rattus norvegicus
100349299 Oryctolagus cuniculus
100717983 Cavia porcellus
100101922 Sus scrofa
479450 Canis lupus familiaris
526824 Bos taurus
395401 Gallus gallus
101105847 Ovis aries
11920 Mus musculus
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