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Browse our anti-GTPase NRas (NRAS) Antibodies

Full name:
anti-GTPase NRas Antibodies (NRAS)
On www.antibodies-online.com are 99 GTPase NRas (NRAS) Antibodies from 18 different suppliers available. Additionally we are shipping GTPase NRas Proteins (17) and GTPase NRas Kits (6) and many more products for this protein. A total of 127 GTPase NRas products are currently listed.
Synonyms:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1
list all antibodies Gene Name GeneID UniProt
NRAS 24605 Q04970
NRAS 18176  
NRAS 4893 P01111

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Most Popular Reactivities for anti-GTPase NRas (NRAS) Antibodies

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anti-Rat (Rattus) GTPase NRas Antibodies:

anti-Mouse (Murine) GTPase NRas Antibodies:

anti-Human GTPase NRas Antibodies:

All available anti-GTPase NRas Antibodies

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Top referenced anti-GTPase NRas Antibodies

  1. Human Monoclonal GTPase NRas Primary Antibody for EIA, WB - ABIN781533 : Rocks, Peyker, Bastiaens: Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors. in Current opinion in cell biology 2006 (PubMed)
    Show all 3 references for ABIN781533

  2. Human Polyclonal GTPase NRas Primary Antibody for EIA, FACS - ABIN360038 : Smalley, Contractor, Nguyen, Xiao, Edwards, Muthusamy, King, Flaherty, Bosenberg, Herlyn, Nathanson: Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression. in Cancer research 2008 (PubMed)
    Show all 2 references for ABIN360038

  3. Human Polyclonal GTPase NRas Primary Antibody for EIA, IHC (p) - ABIN360039 : Banerji, Affolter, Judson, Marais, Workman: BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors. in Molecular cancer therapeutics 2008 (PubMed)
    Show all 2 references for ABIN360039

  4. Human Polyclonal GTPase NRas Primary Antibody for IHC (p), IHC - ABIN409077 : Thomas, Edmiston, Alexander, Millikan, Groben, Hao, Tolbert, Berwick, Busam, Begg, Mattingly, Ollila, Tse, Hummer, Lee-Taylor, Conway: Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007 (PubMed)

  5. Human Monoclonal GTPase NRas Primary Antibody for WB - ABIN1882272 : Hall, Brown: Human N-ras: cDNA cloning and gene structure. in Nucleic acids research 1985 (PubMed)

More Antibodies against GTPase NRas Interaction Partners

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. loss of one allele of Hras (show HRAS Antibodies) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (show HRAS Antibodies) allele. However, loss of one or both alleles of Nras failed to alter tumor burden, either in the absence or presence of Hras (show HRAS Antibodies), after exposure to urethane.

  2. Genetic inactivation of Ezh2 (show EZH2 Antibodies) or Eed (show EED Antibodies) cooperates with NRASQ61K in leukemogenesis.

  3. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  4. Activated NRAS and aberrant Wnt (show WNT2 Antibodies) signaling conspire to drive congenital melanocytic nevus syndrome.

  5. a crucial role of RXRa (show RXRA Antibodies) in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4 (show CDK4 Antibodies)(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 (show TP53 Antibodies) and PTEN (show PTEN Antibodies)

  6. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  7. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  8. NRAS expression is required for the proliferative advantage of human AML (show RUNX1 Antibodies) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (show RUNX1 Antibodies) in vivo

  9. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  10. Cbfbeta (show CBFB Antibodies)-SMMHC (show MYH11 Antibodies) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies)/Bim (show BCL2L11 Antibodies) axis, and define Nras(LSL-G12D); Cbfb (show CBFB Antibodies)(56M) mice as a valuable genetic model for the study of AML (show RUNX1 Antibodies) therapies.

Human GTPase NRas (NRAS) interaction partners

  1. The data revealed the presence of a partial tandem duplication of the MLL (show MLL Antibodies) gene as the only detectable copy number change and 11 non-silent somatic mutations, including DNMT3A (show DNMT3A Antibodies) R882H and NRAS G13D. All somatic lesions were present both at initial MDS (show PAFAH1B1 Antibodies)/MPN (show PRSS27 Antibodies)-U diagnosis and at AML (show RUNX1 Antibodies) presentation at similar mutant allele frequencies.

  2. NRAS mutation is associated with CNS melanoma.

  3. NRAS mutation is associated with melanoma.

  4. Silencing VPS35 (show vps35 Antibodies) increased N-Ras's association with cytoplasmic vesicles, diminished GTP (show AK3 Antibodies) loading of Ras, and inhibited mitogen-activated protein kinase (show MAPK1 Antibodies) signaling and growth of N-Ras-dependent melanoma cells.

  5. By using this model of curative-intent, margin-negative resection in patients at high risk of recurrence, the authors were able to establish a link between mutation location within the K/NRAS gene and the biology of metastatic colorectal cancer.

  6. review focuses on the genes, which are frequently mutated in various cancers and are known to be important in the advance and progression of colorectal cancer and melanoma, namely KRAS, NRAS and BRAF (show BRAF Antibodies)

  7. Report KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer may depend on tumor histology.

  8. SP174 immunohistochemistry allows sensitive detection of NRAS and KRAS Q61R mutants.

  9. multiregion analysis was performed in 60 spatially separated tumor areas according to the pathological tumor node metastasis (pTNM) staging and KRAS, NRAS and BRAF mutations were tested using pyrosequencing.these results suggest the need for multiple RAS testing in different parts of the same tumor and/or more sensitive techniques.

  10. that the presence of NRAS, PTEN (show PTEN Antibodies) and AKT1 (show AKT1 Antibodies) gene mutations may have an influence on the occurrence of CNS metastases in patients with SqCC

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (show TP53 Antibodies) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) Antigen Profile

Antigen Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) antibody
  • African clawed frog N-ras (n-ras) antibody
  • neuroblastoma ras oncogene (Nras) antibody
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) antibody
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) antibody
  • ALPS4 antibody
  • AV095280 antibody
  • fj99a10 antibody
  • H-RAS antibody
  • HRAS antibody
  • N-RAS antibody
  • NRAS antibody
  • NRAS1 antibody
  • NS6 antibody
  • wu:fj99a10 antibody
  • zgc:100761 antibody
  • zras-b1 antibody

Protein level used designations for anti-GTPase NRas (NRAS) Antibodies

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPECIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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