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GTPase NRas antibody (AA 147-179)

NRAS Reactivity: Human FACS, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031131
$578.58
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  • Target See all GTPase NRas (NRAS) Antibodies
    GTPase NRas (NRAS)
    Binding Specificity
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-179
    Reactivity
    • 50
    • 22
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 12
    • 7
    Rabbit
    Clonality
    • 49
    • 12
    Polyclonal
    Conjugate
    • 34
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTPase NRas antibody is un-conjugated
    Application
    • 49
    • 24
    • 8
    • 7
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Pig
    Purification
    Purified
    Immunogen
    A portion of amino acids 147-179 from the human protein was used as the immunogen for this NRAS antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the NRAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the NRAS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    GTPase NRas (NRAS)
    Alternative Name
    NRAS (NRAS Products)
    Synonyms
    NRAS antibody, AV095280 antibody, N-ras antibody, ALPS4 antibody, NRAS1 antibody, NS6 antibody, N-RAS antibody, fj99a10 antibody, wu:fj99a10 antibody, zgc:100761 antibody, zras-b1 antibody, H-RAS antibody, HRAS antibody, GTPase NRas antibody, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog antibody, NRAS proto-oncogene, GTPase antibody, neuroblastoma ras oncogene antibody, neuroblastoma RAS viral oncogene homolog antibody, Tsp_01117 antibody, nras.L antibody, Nras antibody, NRAS antibody, nras antibody
    Background
    NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
    UniProt
    P01111
    Pathways
    p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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