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Browse our anti-AKT2 (AKT2) Antibodies

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 Antibodies (AKT2)
On www.antibodies-online.com are 400 V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies from 31 different suppliers available. Additionally we are shipping AKT2 Proteins (19) and AKT2 Kits (15) and many more products for this protein. A total of 450 AKT2 products are currently listed.
Synonyms:
2410016A19Rik, AKT2, akt2-a, AW554154, cb945, HIHGHH, PKB, PKBB, PKBBETA, pkbss, PRKBB, RAC-BETA, v-akt2

Most Popular Reactivities for anti-AKT2 (AKT2) Antibodies

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anti-Mouse (Murine) AKT2 Antibodies:

anti-Human AKT2 Antibodies:

anti-Rat (Rattus) AKT2 Antibodies:

All available anti-AKT2 Antibodies

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Top referenced anti-AKT2 Antibodies

  1. Human Polyclonal AKT2 Primary Antibody for EIA, IHC (p) - ABIN359079 : George, Rochford, Wolfrum, Gray, Schinner, Wilson, Soos, Murgatroyd, Williams, Acerini, Dunger, Barford, Umpleby, Wareham, Davies, Schafer, Stoffel, ORahilly, Barroso: A family with severe insulin resistance and diabetes due to a mutation in AKT2. in Science (New York, N.Y.) 2004 (PubMed)
    Show all 5 references for ABIN359079

  2. Human Polyclonal AKT2 Primary Antibody for EIA - ABIN358304 : Xu, Sakon, Nagano, Hiraoka, Yamamoto, Hayashi, Dono, Nakamori, Umeshita, Ito, Matsuura, Monden: Akt2 expression correlates with prognosis of human hepatocellular carcinoma. in Oncology reports 2003 (PubMed)
    Show all 5 references for ABIN358304

  3. Human Polyclonal AKT2 Primary Antibody for EIA, IHC (p) - ABIN359081 : Shim, Kang, Jeon, Kang, Chang, Kim: Protein kinase B inhibits apoptosis induced by actinomycin D in ECV304 cells through phosphorylation of caspase 8. in Archives of biochemistry and biophysics 2004 (PubMed)
    Show all 4 references for ABIN359081

  4. Human Polyclonal AKT2 Primary Antibody for EIA, WB - ABIN359080 : Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN359080

  5. Cow (Bovine) Polyclonal AKT2 Primary Antibody for WB - ABIN2792145 : Tan, Timakhov, Rao, Altomare, Xu, Liu, Gao, Jhanwar, Di Cristofano, Wiest, Knepper, Testa: A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. in Cancer research 2008 (PubMed)

More Antibodies against AKT2 Interaction Partners

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Akt2(-/-) mice survive hepatic Akt1 (show AKT1 Antibodies) deletion but all develop spontaneous hepatocellular carcinoma. They are insulin (show INS Antibodies) resistant. Akt2(-/-) mice are not resistant to diethylnitrosamine hepatocarcinogenesis. They have a high incidence of lung metastasis.

  2. rescued the hepatic regenerative capability in Akt1 (show AKT1 Antibodies)-deficient and Akt2-deficient mice

  3. Sustained endothelial Akt1/2 (show JAG1 Antibodies) signalling is critical in main (show NOTCH1 Antibodies)taining vascular stability and homeostasis, thereby preserving tissue and organ function.

  4. Akt2 upregulates dendritic cell migration at least in part by ETS1 (show ETS1 Antibodies)-dependent stimulation of IP3R2 (show ITPR2 Antibodies) transcription.

  5. In viable Akt (show AKT1 Antibodies) three-isoforms conditional knockout mice, total Akt (show AKT1 Antibodies) levels were reduced in the adult brain. They had increased levels of phosphorylated tau, GSK3alpha and PKA substrates. No significant changes in p-tau levels were found in Akt2(-/-)mice.

  6. results suggest that short-term coadministration of HU and Akti XII has immediate benefits for acute vaso-occlusive events and survival in SCD (show SCD Antibodies) mice exceeding those seen for single therapy.

  7. untreated Akt1 (show AKT1 Antibodies) and Akt2/Akt3 (show AKT3 Antibodies) double knockout mice display significant hearing loss, indicating a role for these isoforms in normal hearing.

  8. Tmod3 (show TMOD3 Antibodies) is a novel Akt2 effector that mediates insulin (show INS Antibodies)-induced cortical actin remodelling and subsequent GLUT4 (show SLC2A4 Antibodies) membrane insertion

  9. These data suggest that suppression of lipolysis by insulin (show INS Antibodies) in hyperinsulinaemic states can take place in the absence of Akt2.

  10. AKT2 activity in skeletal muscle critically affects lipid accumulation in the livers of Pten (show PTEN Antibodies)(+/+) /Akt2(+/+) and Pten (show PTEN Antibodies)(+/-) /Akt2(+/+) mice.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. High constitutive Akt2 activity in U937 promonocytes: effective reduction of Akt2 phosphorylation by the histamine H2-receptor (show HRH2 Antibodies) and the beta2-adrenergic receptor (show ADRB2 Antibodies)

  2. High AKT2 expression is associated with ovarian cancer.

  3. Akt1 (show AKT1 Antibodies) and Akt2 activated both SREBP-1 (show SREBF1 Antibodies) and SREBP-2 (show SREBF2 Antibodies), whereas Akt3 (show AKT3 Antibodies) upregulated SREBP-1 (show SREBF1 Antibodies) to enhance hepatitis C virus translation.

  4. Active, phosphorylated Akt2 translocates to the nucleus in Notch (show NOTCH1 Antibodies)-expressing cells, resulting in GSK-3beta (show GSK3b Antibodies) inactivation in this compartment.

  5. controls endothelial Jagged1 (show JAG1 Antibodies) expression and, thereby, Notch (show NOTCH1 Antibodies) signalling regulating VSMC maintenance.

  6. These studies identify Akt2 as a critical kinase that regulates radixin (show RDX Antibodies) phosphorylation and leads to Mrp-2 (show ABCC2 Antibodies) translocation and function.

  7. miR (show MLXIP Antibodies)-612 directly suppressed AKT2, which in turn inhibited the downstream epithelial-mesenchymal transition-related signaling pathway.

  8. the correlation between RLN2 (show RLN1 Antibodies) and p-AKT (show AKT1 Antibodies) or RLN2 (show RLN1 Antibodies) and p-ERK1/2 (show MAPK1/3 Antibodies) expression was investigated.

  9. the biological effect of Akt2 in colorectal cancer cells

  10. miR (show MLXIP Antibodies)-137 which is frequently down-regulated in gastric cancer is potentially involved in gastric cancer tumorigenesis and metastasis by regulating AKT2 related signal pathways

Zebrafish V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. EDN1 plays an important role in hepatocellular carcinoma progression by activating the PI3K/AKT pathway and is regulated by miR-1.

  2. akt2 has a role in an integrative pathway directly linking glucose, Glut1 (show SLC2A1 Antibodies) expression, and activation of apoptosis

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Profilin (show PFN1 Antibodies)-dependent dissociation of G-actin (show ACTB Antibodies)-Tbeta4 complexes simultaneously liberates actin for filament assembly and facilitates Tbeta4 binding to integrin-linked kinase (ILK (show ILK Antibodies)) in the lamellipodia.

AKT2 Antigen Profile

Antigen Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Alternative names and synonyms associated with AKT2

  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) antibody
  • v-akt murine thymoma viral oncogene homolog 2 (akt2) antibody
  • thymoma viral proto-oncogene 2 (Akt2) antibody
  • v-akt murine thymoma viral oncogene homolog 2 (Akt2) antibody
  • 2410016A19Rik antibody
  • AKT2 antibody
  • akt2-a antibody
  • AW554154 antibody
  • cb945 antibody
  • HIHGHH antibody
  • PKB antibody
  • PKBB antibody
  • PKBBETA antibody
  • pkbss antibody
  • PRKBB antibody
  • RAC-BETA antibody
  • v-akt2 antibody

Protein level used designations for AKT2

v-akt murine thymoma viral oncogene homolog 2 , RAC-beta serine/threonine-protein kinase , AKT2 kinase , RAC-beta serine/threonine-protein kinase-like , serine/threonine protein kinase , PKB beta , RAC-PK-beta , RAC-beta serine/threonine protein kinase , protein kinase Akt-2 , protein kinase B beta , protein kinase B, beta , murine thymoma viral (v-akt) homolog-2 , rac protein kinase beta , RAC protein kinase beta RAC-PK beta , murine thymoma viral (v-akt) oncogene homolog 2 , thymoma viral proto-oncogene 2 , PKB beta-A , RAC-PK-beta-A , RAC-beta serine/threonine-protein kinase A , protein kinase Akt-2-A , protein kinase B, beta-A , protein kinase B

GENE ID SPECIES
456035 Pan troglodytes
700591 Macaca mulatta
100144709 Xenopus (Silurana) tropicalis
100388080 Callithrix jacchus
100454279 Pongo abelii
100499544 Felis catus
100468763 Ailuropoda melanoleuca
11652 Mus musculus
208 Homo sapiens
25233 Rattus norvegicus
378972 Danio rerio
379783 Xenopus laevis
373973 Gallus gallus
449021 Canis lupus familiaris
100127478 Sus scrofa
534923 Bos taurus
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