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Browse our anti-AKT2 (AKT2) Antibodies

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 Antibodies (AKT2)
On are 423 V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies from 32 different suppliers available. Additionally we are shipping AKT2 Proteins (24) and AKT2 Kits (19) and many more products for this protein. A total of 482 AKT2 products are currently listed.
2410016A19Rik, AKT2, akt2-a, AW554154, cb945, HIHGHH, PKB, PKBB, PKBBETA, pkbss, PRKBB, RAC-BETA, v-akt2

Most Popular Reactivities for anti-AKT2 (AKT2) Antibodies

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anti-Mouse (Murine) AKT2 Antibodies:

anti-Human AKT2 Antibodies:

anti-Rat (Rattus) AKT2 Antibodies:

All available anti-AKT2 Antibodies

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Top referenced anti-AKT2 Antibodies

  1. Human Polyclonal AKT2 Primary Antibody for EIA, IHC (p) - ABIN359079 : George, Rochford, Wolfrum, Gray, Schinner, Wilson, Soos, Murgatroyd, Williams, Acerini, Dunger, Barford, Umpleby, Wareham, Davies, Schafer, Stoffel, ORahilly, Barroso: A family with severe insulin resistance and diabetes due to a mutation in AKT2. in Science (New York, N.Y.) 2004 (PubMed)
    Show all 5 references for ABIN359079

  2. Human Polyclonal AKT2 Primary Antibody for EIA - ABIN358304 : Xu, Sakon, Nagano, Hiraoka, Yamamoto, Hayashi, Dono, Nakamori, Umeshita, Ito, Matsuura, Monden: Akt2 expression correlates with prognosis of human hepatocellular carcinoma. in Oncology reports 2003 (PubMed)
    Show all 5 references for ABIN358304

  3. Human Polyclonal AKT2 Primary Antibody for EIA, WB - ABIN359080 : Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN359080

  4. Human Polyclonal AKT2 Primary Antibody for FACS, IF - ABIN391023 : Jones, Ganeshaguru, Anderson, Jackson, Bruckdorfer, Low, Palmqvist, Prentice, Hoffbrand, Mehta, Wickremasinghe: Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis. in Blood 2003 (PubMed)
    Show all 2 references for ABIN391023

  5. Cow (Bovine) Polyclonal AKT2 Primary Antibody for IHC, WB - ABIN2792145 : Tan, Timakhov, Rao, Altomare, Xu, Liu, Gao, Jhanwar, Di Cristofano, Wiest, Knepper, Testa: A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. in Cancer research 2008 (PubMed)

More Antibodies against AKT2 Interaction Partners

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. BAY 1125976 is a potent and highly selective allosteric AKT1 (show AKT1 Antibodies)/2 inhibitor.

  2. AKT2 inhibition induces a unique mitochondrial-dependent DNA degradation pathway by activating nucleus translocation of AIF (show AIFM1 Antibodies) and EndoG (show ENDOG Antibodies) during cardiac ischemia.

  3. Akt2 ablation may protect against paraquat toxicity-induced cardiac contractile defect and apoptosis possibly via regulation of Nrf2 (show NFE2L2 Antibodies) activation and mitochondrial homeostasis.

  4. Loss of Akt2 enhanced lung tumor development.

  5. Akt2(-/-) mice survive hepatic Akt1 (show AKT1 Antibodies) deletion but all develop spontaneous hepatocellular carcinoma. They are insulin (show INS Antibodies) resistant. Akt2(-/-) mice are not resistant to diethylnitrosamine hepatocarcinogenesis. They have a high incidence of lung metastasis.

  6. rescued the hepatic regenerative capability in Akt1 (show AKT1 Antibodies)-deficient and Akt2-deficient mice

  7. Sustained endothelial Akt1/2 (show JAG1 Antibodies) signalling is critical in main (show NOTCH1 Antibodies)taining vascular stability and homeostasis, thereby preserving tissue and organ function.

  8. Akt2 upregulates dendritic cell migration at least in part by ETS1 (show ETS1 Antibodies)-dependent stimulation of IP3R2 (show ITPR2 Antibodies) transcription.

  9. In viable Akt (show AKT1 Antibodies) three-isoforms conditional knockout mice, total Akt (show AKT1 Antibodies) levels were reduced in the adult brain. They had increased levels of phosphorylated tau, GSK3alpha and PKA substrates. No significant changes in p-tau levels were found in Akt2(-/-)mice.

  10. results suggest that short-term coadministration of HU and Akti XII has immediate benefits for acute vaso-occlusive events and survival in SCD (show SCD Antibodies) mice exceeding those seen for single therapy.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Quinoline-type inhibitors bind in the Akt2 PH domain.

  2. TGF-beta (show TGFB1 Antibodies) signaling through Akt2 induces phosphorylation of heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1 (show PCBP1 Antibodies)) at serine-43 (p-hnRNP E1 (show PCBP1 Antibodies)), driving epithelial to mesenchymal transition and metastasis.

  3. miR (show MLXIP Antibodies)-29b plays an important role in TGF-beta1 (show TGFB1 Antibodies)-mediated epithelial-mesenchymal transition in ARPE-19 cells by targeting Akt2.

  4. miR (show MLXIP Antibodies)-148a functions as tumor suppressor in Renal cell carcinoma (show MOK Antibodies) by targeting AKT2.

  5. This was further verified in gene expression analyses, showing downregulation of genes involved in glucose metabolism. Additionally, both AKT1 (show AKT1 Antibodies) KO and AKT2 KO demonstrated an impaired fatty acid metabolism. However, genes were upregulated in the Wnt (show WNT2 Antibodies) and cell proliferation pathways, which could oppose this effect. AKT (show AKT1 Antibodies) inhibition should therefore be combined with other effectors to attain the best effect.

  6. Data indicate that proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-akt (Akt (show AKT1 Antibodies)) phosphorylates distinct sites than SRPK1 (show SRPK1 Antibodies) protein within the arginine-serine (RS) domain of Lamin B Receptor (LBR (show LBR Antibodies)).

  7. MiR (show MLXIP Antibodies)-650 could inhibit the proliferation, migration and invasion of rheumatoid arthritis synovial fibroblasts through targeted regulation of AKT2 expression.

  8. High AKT2 expression is associated with gallbladder cancer.

  9. miR (show MLXIP Antibodies)-302b inhibits SMMC-7721 cell invasion and metastasis by targeting AKT2

  10. No association has been found between AKT2 polymorphisms and oesophageal squamous cell carcinoma risk.

Zebrafish V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Study reports that Appl1 (show APPL1 Antibodies) regulates the activity of Akt (show AKT1 Antibodies) and, importantly, its downstream signaling specificity from an endosomal compartment, with profound implications for development.

  2. EDN1 plays an important role in hepatocellular carcinoma progression by activating the PI3K/AKT pathway and is regulated by miR-1.

  3. akt2 has a role in an integrative pathway directly linking glucose, Glut1 (show SLC2A1 Antibodies) expression, and activation of apoptosis

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Profilin (show PFN1 Antibodies)-dependent dissociation of G-actin (show ACTB Antibodies)-Tbeta4 complexes simultaneously liberates actin for filament assembly and facilitates Tbeta4 binding to integrin-linked kinase (ILK (show ILK Antibodies)) in the lamellipodia.

AKT2 Antigen Profile

Antigen Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Alternative names and synonyms associated with AKT2

  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) antibody
  • v-akt murine thymoma viral oncogene homolog 2 (akt2) antibody
  • thymoma viral proto-oncogene 2 (Akt2) antibody
  • v-akt murine thymoma viral oncogene homolog 2 (Akt2) antibody
  • 2410016A19Rik antibody
  • AKT2 antibody
  • akt2-a antibody
  • AW554154 antibody
  • cb945 antibody
  • HIHGHH antibody
  • PKB antibody
  • PKBB antibody
  • PKBBETA antibody
  • pkbss antibody
  • PRKBB antibody
  • RAC-BETA antibody
  • v-akt2 antibody

Protein level used designations for AKT2

v-akt murine thymoma viral oncogene homolog 2 , RAC-beta serine/threonine-protein kinase , AKT2 kinase , RAC-beta serine/threonine-protein kinase-like , serine/threonine protein kinase , PKB beta , RAC-PK-beta , RAC-beta serine/threonine protein kinase , protein kinase Akt-2 , protein kinase B beta , protein kinase B, beta , murine thymoma viral (v-akt) homolog-2 , rac protein kinase beta , RAC protein kinase beta RAC-PK beta , murine thymoma viral (v-akt) oncogene homolog 2 , thymoma viral proto-oncogene 2 , PKB beta-A , RAC-PK-beta-A , RAC-beta serine/threonine-protein kinase A , protein kinase Akt-2-A , protein kinase B, beta-A , protein kinase B

456035 Pan troglodytes
700591 Macaca mulatta
100144709 Xenopus (Silurana) tropicalis
100388080 Callithrix jacchus
100454279 Pongo abelii
100499544 Felis catus
100468763 Ailuropoda melanoleuca
11652 Mus musculus
208 Homo sapiens
25233 Rattus norvegicus
378972 Danio rerio
379783 Xenopus laevis
373973 Gallus gallus
449021 Canis lupus familiaris
100127478 Sus scrofa
534923 Bos taurus
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