Browse our anti-AKT2 (AKT2) Antibodies

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 2 Antibodies (AKT2)
On www.antibodies-online.com are 458 V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies from 32 different suppliers available. Additionally we are shipping AKT2 Proteins (28) and AKT2 Kits (22) and many more products for this protein. A total of 524 AKT2 products are currently listed.
Synonyms:
2410016A19Rik, AKT2, akt2-a, AW554154, cb945, HIHGHH, PKB, PKBB, PKBBETA, pkbss, PRKBB, RAC-BETA, v-akt2

Most Popular Reactivities for anti-AKT2 (AKT2) Antibodies

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anti-Mouse (Murine) AKT2 Antibodies:

anti-Human AKT2 Antibodies:

anti-Rat (Rattus) AKT2 Antibodies:

All available anti-AKT2 Antibodies

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Top referenced anti-AKT2 Antibodies

  1. Human Polyclonal AKT2 Primary Antibody for EIA - ABIN358304 : George, Rochford, Wolfrum, Gray, Schinner, Wilson, Soos, Murgatroyd, Williams, Acerini, Dunger, Barford, Umpleby, Wareham, Davies, Schafer, Stoffel, ORahilly, Barroso: A family with severe insulin resistance and diabetes due to a mutation in AKT2. in Science (New York, N.Y.) 2004 (PubMed)
    Show all 5 references for 358304

  2. Human Polyclonal AKT2 Primary Antibody for EIA, WB - ABIN359080 : Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 359080

  3. Human Polyclonal AKT2 Primary Antibody for FACS, IF - ABIN391023 : Jones, Ganeshaguru, Anderson, Jackson, Bruckdorfer, Low, Palmqvist, Prentice, Hoffbrand, Mehta, Wickremasinghe: Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis. in Blood 2003 (PubMed)
    Show all 2 references for 391023

  4. Human Monoclonal AKT2 Primary Antibody for IHC, ELISA - ABIN1043775 : Altomare, Kozak, Sonoda, Testa: Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene. in Cytogenetics and cell genetics 1997 (PubMed)

  5. Cow (Bovine) Polyclonal AKT2 Primary Antibody for IHC, WB - ABIN2792145 : Tan, Timakhov, Rao, Altomare, Xu, Liu, Gao, Jhanwar, Di Cristofano, Wiest, Knepper, Testa: A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. in Cancer research 2008 (PubMed)

More Antibodies against AKT2 Interaction Partners

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Results indicate that AKT2 modulates pulmonary fibrosis through inducing TGF-beta1 (show TGFB1 Antibodies) and IL-13 (show IL13 Antibodies) production by macrophages, and inhibition of AKT2 may be a potential strategy for treating Idiopathic pulmonary fibrosis.

  2. Sirt1 (show SIRT1 Antibodies) significantly reduced the levels of raptor (show RPTOR Antibodies) and inactivated mammalian target of rapamycin (mTOR (show FRAP1 Antibodies))C1 signal by interacting with Akt2.

  3. This review summarises and discusses the consequences of genetic deletions of Akt (show AKT1 Antibodies) isoforms in adult mice and their implications for cancer therapy. Whereas combined Akt1 (show AKT1 Antibodies) and Akt2 rapidly induced mortality, hepatic Akt (show AKT1 Antibodies) inhibition induced liver injury that promotes hepatocellular carcinoma.

  4. Rac1 activation is caused by membrane translocation of a guanine nucleotide exchange factor (show ARHGEF12 Antibodies) FLJ00068 in Akt2-mediated insulin (show INS Antibodies) signaling in mouse skeletal muscle.

  5. BAY 1125976 is a potent and highly selective allosteric AKT1 (show AKT1 Antibodies)/2 inhibitor.

  6. AKT2 inhibition induces a unique mitochondrial-dependent DNA degradation pathway by activating nucleus translocation of AIF (show AIFM1 Antibodies) and EndoG (show ENDOG Antibodies) during cardiac ischemia.

  7. Akt2 ablation may protect against paraquat toxicity-induced cardiac contractile defect and apoptosis possibly via regulation of Nrf2 (show NFE2L2 Antibodies) activation and mitochondrial homeostasis.

  8. Loss of Akt2 enhanced lung tumor development.

  9. Akt2(-/-) mice survive hepatic Akt1 (show AKT1 Antibodies) deletion but all develop spontaneous hepatocellular carcinoma. They are insulin (show INS Antibodies) resistant. Akt2(-/-) mice are not resistant to diethylnitrosamine hepatocarcinogenesis. They have a high incidence of lung metastasis.

  10. rescued the hepatic regenerative capability in Akt1 (show AKT1 Antibodies)-deficient and Akt2-deficient mice

Human V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Results indicate that AKT2 modulates pulmonary fibrosis through inducing TGF-beta1 (show TGFB1 Antibodies) and IL-13 (show IL13 Antibodies) production by macrophages, and inhibition of AKT2 may be a potential strategy for treating Idiopathic pulmonary fibrosis.

  2. The p.Glu17Lys mutation of AKT2 confers low-level constitutive activity upon the kinase and produces hypoglycemia with suppressed fatty acid release from adipose tissue, but not fatty liver, hypertriglyceridemia, or elevated hepatic de novo lipogenesis.

  3. Studies provide evidence that AKT2 counteracts oxidative-stress-induced (show SQSTM1 Antibodies) apoptosis and is required for alpha-beta thymocyte survival and differentiation. Also, it plays a critical role in antagonizing cardiomyocyte apoptosis. [review]

  4. Akt2 role in the human lung cancer cell proliferation, growth, motility, invasion and endothelial cell tube formation

  5. High expressions of AKT1 (show AKT1 Antibodies) and AKT2 through possible relation with androgen may cause granulosa cells dysfunction in the +HA PCOS patients.

  6. This study demonstrates novel regulatory circuits involving miR (show MLXIP Antibodies)-148a-3p/ERBB3 (show ERBB3 Antibodies)/AKT2/c-myc (show MYC Antibodies) and DNMT1 (show DNMT1 Antibodies) that controls bladder cancer progression, which may be useful in the development of more effective therapies against bladder cancer.

  7. Both in our animal model and in human Age-related macular degeneration (AMD (show AMD1 Antibodies)), the AKT2-NF-kappaB (show NFKB1 Antibodies)-LCN-2 (show LCN2 Antibodies) signalling axis is involved in activating the inflammatory response.

  8. identified a novel association between the coding variant (p.Pro50Thr) in AKT2 and fasting plasma insulin (show INS Antibodies) (FI), a gene in which rare fully penetrant mutations are causal for monogenic glycemic disorders. Carriers of the FI-increasing allele had increased 2-h insulin (show INS Antibodies) values, decreased insulin (show INS Antibodies) sensitivity, and increased risk of type 2 diabetes.

  9. AKT2 can regulate miR (show MLXIP Antibodies)-200a in a histology- or stage-specific manner and this regulation is independent of subsequent involvement of miR (show MLXIP Antibodies)-200a in epithelial-mesenchymal transition.

  10. This review summarises and discusses the consequences of genetic deletions of Akt (show AKT1 Antibodies) isoforms in adult mice and their implications for cancer therapy. Whereas combined Akt1 (show AKT1 Antibodies) and Akt2 rapidly induced mortality, hepatic Akt (show AKT1 Antibodies) inhibition induced liver injury that promotes hepatocellular carcinoma.

Zebrafish V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Study reports that Appl1 (show APPL1 Antibodies) regulates the activity of Akt (show AKT1 Antibodies) and, importantly, its downstream signaling specificity from an endosomal compartment, with profound implications for development.

  2. EDN1 plays an important role in hepatocellular carcinoma progression by activating the PI3K/AKT pathway and is regulated by miR-1.

  3. akt2 has a role in an integrative pathway directly linking glucose, Glut1 (show SLC2A1 Antibodies) expression, and activation of apoptosis

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Profilin (show PFN1 Antibodies)-dependent dissociation of G-actin (show ACTB Antibodies)-Tbeta4 complexes simultaneously liberates actin for filament assembly and facilitates Tbeta4 binding to integrin-linked kinase (ILK (show ILK Antibodies)) in the lamellipodia.

AKT2 Antigen Profile

Antigen Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Alternative names and synonyms associated with AKT2

  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) antibody
  • v-akt murine thymoma viral oncogene homolog 2 (akt2) antibody
  • thymoma viral proto-oncogene 2 (Akt2) antibody
  • v-akt murine thymoma viral oncogene homolog 2 (Akt2) antibody
  • 2410016A19Rik antibody
  • AKT2 antibody
  • akt2-a antibody
  • AW554154 antibody
  • cb945 antibody
  • HIHGHH antibody
  • PKB antibody
  • PKBB antibody
  • PKBBETA antibody
  • pkbss antibody
  • PRKBB antibody
  • RAC-BETA antibody
  • v-akt2 antibody

Protein level used designations for AKT2

v-akt murine thymoma viral oncogene homolog 2 , RAC-beta serine/threonine-protein kinase , AKT2 kinase , RAC-beta serine/threonine-protein kinase-like , serine/threonine protein kinase , PKB beta , RAC-PK-beta , RAC-beta serine/threonine protein kinase , protein kinase Akt-2 , protein kinase B beta , protein kinase B, beta , murine thymoma viral (v-akt) homolog-2 , rac protein kinase beta , RAC protein kinase beta RAC-PK beta , murine thymoma viral (v-akt) oncogene homolog 2 , thymoma viral proto-oncogene 2 , PKB beta-A , RAC-PK-beta-A , RAC-beta serine/threonine-protein kinase A , protein kinase Akt-2-A , protein kinase B, beta-A , protein kinase B

GENE ID SPECIES
456035 Pan troglodytes
700591 Macaca mulatta
100144709 Xenopus (Silurana) tropicalis
100388080 Callithrix jacchus
100454279 Pongo abelii
100499544 Felis catus
100468763 Ailuropoda melanoleuca
11652 Mus musculus
208 Homo sapiens
25233 Rattus norvegicus
378972 Danio rerio
379783 Xenopus laevis
373973 Gallus gallus
449021 Canis lupus familiaris
100127478 Sus scrofa
534923 Bos taurus
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