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Browse our anti-CDK2 (CDK2) Antibodies

Full name:
anti-Cyclin-Dependent Kinase 2 Antibodies (CDK2)
On are 276 Cyclin-Dependent Kinase 2 (CDK2) Antibodies from 34 different suppliers available. Additionally we are shipping CDK2 Kits (43) and CDK2 Proteins (33) and many more products for this protein. A total of 394 CDK2 products are currently listed.
A630093N05Rik, cdk2L, CDKN2, CINP, eg1, MGC84068, p33(CDK2), wu:fa10c02, zgc:56598, zgc:77684
list all antibodies Gene Name GeneID UniProt
CDK2 362817  
CDK2 1017 P24941
CDK2 12566 P97377

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Most Popular Reactivities for anti-CDK2 (CDK2) Antibodies

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Top referenced anti-CDK2 Antibodies

  1. Dog (Canine) Monoclonal CDK2 Primary Antibody for BI, IP - ABIN967776 : Hinds, Mittnacht, Dulic, Arnold, Reed, Weinberg: Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. in Cell 1992 (PubMed)
    Show all 5 references for ABIN967776

  2. Human Polyclonal CDK2 Primary Antibody for EIA, WB - ABIN358106 : Bicaku, Patel, Acevedo-Duncan: Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells. in Tissue & cell 2005 (PubMed)
    Show all 5 references for ABIN358106

  3. Human Polyclonal CDK2 Primary Antibody for FACS, IHC (p) - ABIN391746 : Moshinsky, Bellamacina, Boisvert, Huang, Hui, Jancarik, Kim, Rice: SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 references for ABIN391746

  4. Human Polyclonal CDK2 Primary Antibody for DB - ABIN389996 : Elledge, Spottswood: A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1. in The EMBO journal 1991 (PubMed)
    Show all 4 references for ABIN389996

  5. Human Polyclonal CDK2 Primary Antibody for EIA - ABIN358539 : Ninomiya-Tsuji, Nomoto, Yasuda, Reed, Matsumoto: Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for ABIN358539

  6. Human Monoclonal CDK2 Primary Antibody for WB - ABIN1106646 : Luo, Zhang, Dastvan, Yanagawa, Reidy, Zhang, Yang, Wilson, McManus: Ubiquitin-dependent proteolysis of cyclin D1 is associated with coxsackievirus-induced cell growth arrest. in Journal of virology 2002 (PubMed)
    Show all 4 references for ABIN1106646

  7. Human Polyclonal CDK2 Primary Antibody for WB - ABIN389540 : Kino, Tsukamoto, Chrousos: Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr. in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 3 references for ABIN389540

  8. Human Polyclonal CDK2 Primary Antibody for EIA, IHC (p) - ABIN359658 : Chow, Siu, Ho, Ma, Ho, Poon: Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN359658

  9. Human Polyclonal CDK2 Primary Antibody for IF, ELISA - ABIN1533672 : Gray, Wodicka, Thunnissen, Norman, Kwon, Espinoza, Morgan, Barnes, LeClerc, Meijer, Kim, Lockhart, Schultz: Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. in Science (New York, N.Y.) 1998 (PubMed)

More Antibodies against CDK2 Interaction Partners

Xenopus laevis Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. evidence that cyclin A1 (show CCNA1 Antibodies)-associated activity is a mediator of apoptosis and that cyclin A1 (show CCNA1 Antibodies)/Cdk2 is sufficient to induce apoptosis

Human Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. show thata combining cyclin-dependent kinase 2 (CDK2) antagonism and ubiquitin thioesterase 33 (USP33 (show USP33 Antibodies)) depletion augments anaphase catastrophe via changes in centrosomal protein of 110 kDa (CP110 (show CCP110 Antibodies)) protein expression.

  2. Foxo3 (show FOXO3 Antibodies) circular RNA retards cell cycle progression via forming ternary complexes with p21 (show CDKN1A Antibodies) and CDK2.

  3. our study reveals a novel function of CDK2 in EGF (show EGF Antibodies)-induced cell transformation and the associated signal transduction pathways. This indicates that CDK2 is a useful molecular target for the chemoprevention and therapy against skin cancer.

  4. Study describes a positive feedback loop centred on cyclin A2 (show CCNA2 Antibodies)-Cdk2 inhibition of interphase APC (show APC Antibodies)/C-Cdc20 (show CDC20 Antibodies) to allow further cyclin A2 (show CCNA2 Antibodies) accumulation and mitotic entry.

  5. both cell lines feature a significant reduction of CDK2 expression verified at the RNA and protein level, respectively

  6. ovary tumors with elevated CCNE1 (show CCNE1 Antibodies) expression may be staged for Cdk2-targeted therapy

  7. Centriolar satellites build a centrosomal microcephaly protein complex critical for human neurodevelopment that promotes CDK2 centrosomal localization and centriole duplication.

  8. PIWIL2 (show PIWIL2 Antibodies) has a role in promoting progression of non-small cell lung cancer by inducing CDK2 and Cyclin A (show CCNA2 Antibodies) expression

  9. In G28 cells, a dosedependent induction of CDK2, p21 and cyclin D was observed between 10 and 50 microM roscovitine after 72 h, however, at the highest concentration of 100 microM, all investigated genes were downregulated.

  10. Identified ING5 (show ING5 Antibodies) as a novel CDK2 substrate. ING5 (show ING5 Antibodies) is phosphorylated at a single site, threonine 152, by cyclin E (show CCNE1 Antibodies)/CDK2 and cyclin A (show CCNA2 Antibodies)/CDK2. This site is also phosphorylated in cells in a cell cycle dependent manner, consistent with it being a CDK2 substrate.

Mouse (Murine) Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. RingoA (show SPDYA Antibodies) is an important activator of Cdk2 at meiotic telomeres.

  2. Foxo3 (show FOXO3 Antibodies) circular RNA retards cell cycle progression via forming ternary complexes with p21 (show D4S234E Antibodies) and CDK2.

  3. Results identify phosphorylation of CDK2 at tyrosine 160 as a gate-keeping mechanism for hepatocyte proliferation.

  4. Sox2 (show SOX2 Antibodies) phosphorylation by Cdk2 promotes the establishment but not the maintenance of the pluripotent state.

  5. Our data indicate that Cdk2 and Cdk4 (show CDK4 Antibodies) play important overlapping roles in homeostatic and stress hematopoiesis, which need to be considered when using broad-spectrum cyclin-dependent kinase (show CDK1 Antibodies) inhibitors for cancer therapy.

  6. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.

  7. CDK4 (show CDK4 Antibodies) is a critical downstream target of MEN1 (show MEN1 Antibodies)-dependent tumor suppression and is required for tumorigenic proliferation in the pituitary and pancreatic islet, whereas CDK2 is dispensable for tumorigenesis in these neuroendocrine cell types.

  8. Our results highlight an important role for p-CDK2(39) in influencing silencing of the sex chromosomes during male meiosis by interacting with gamma-H2AX.

  9. abnormal pairing and synapsis of homologous chromosomes, heterologous chromosome associations, unrepaired double-strand DNA breaks, disruptions in telomeric structure and defects in cyclin-dependent-kinase 2 localization

  10. Results show that CDK2 phosphorylates Thr (show TRH Antibodies)-156 in GATA3 (show GATA3 Antibodies).

Zebrafish Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21 (show CDKN1A Antibodies), PCNA (show PCNA Antibodies) and cdk2, but only weakly influences cyclin B1 (show CCNB1 Antibodies), cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.

  2. PI3-kinase (show PIK3CA Antibodies) and Akt (show AKT1 Antibodies) participate in insulin (show INS Antibodies) stimulation of p34cdc2 (show CDK1 Antibodies) activation in zebrafish oocyte with phosphodiesterase 3 as a potential downstream target.

  3. an essential role for UHRF1 (show UHRF1 Antibodies) phosphorylation by cyclin-dependent kinase 2/cyclin A2 (show CCNA2 Antibodies) during early vertebrate development

Cow (Bovine) Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. cyclin D1 (show CCND1 Antibodies), CDK2 and CDK4 (show CDK4 Antibodies) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation

CDK2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Alternative names and synonyms associated with CDK2

  • MGC84068 protein (MGC84068) antibody
  • cyclin-dependent kinase 2 interacting protein (CINP) antibody
  • Cyclin-dependent kinase 2-interacting protein (cinp) antibody
  • cyclin dependent kinase 2 (Cdk2) antibody
  • cyclin-dependent kinase 2 (CDK2) antibody
  • cyclin-dependent kinase 2 (Cdk2) antibody
  • cyclin-dependent kinase 2 (cdk2) antibody
  • cyclin-dependent kinase 2 (CDK2) (Cdk2) antibody
  • cyclin-dependent kinase-2 alpha (LOC100154715) antibody
  • A630093N05Rik antibody
  • cdk2L antibody
  • CDKN2 antibody
  • CINP antibody
  • eg1 antibody
  • MGC84068 antibody
  • p33(CDK2) antibody
  • wu:fa10c02 antibody
  • zgc:56598 antibody
  • zgc:77684 antibody

Protein level used designations for CDK2

MGC84068 protein , Cyclin-dependent kinase 2-interacting protein , cyclin-dependent kinase 2 interacting protein , cyclin-dependent kinase 2-interacting protein , cell division protein kinase 2 , cyclin dependent kinase 2-alpha , cyclin-dependent kinase 2 , cdc2-related protein kinase , cell devision kinase 2 , p33 protein kinase , CDC2 homolog Eg1 protein kinase , Cell division protein kinase 2

444599 Xenopus laevis
744050 Pan troglodytes
100196126 Salmo salar
362817 Rattus norvegicus
1017 Homo sapiens
12566 Mus musculus
406715 Danio rerio
399314 Xenopus laevis
100529062 Gallus gallus
606931 Canis lupus familiaris
519217 Bos taurus
100134865 Oryctolagus cuniculus
100127490 Sus scrofa
100714324 Cavia porcellus
100860751 Capra hircus
100216433 Ovis aries
101844411 Mesocricetus auratus
100689039 Cricetulus griseus
100154715 Sus scrofa
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