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Browse our PDK1 (PDK1) ELISA Kits

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Pyruvate Dehydrogenase Kinase, Isozyme 1 ELISA Kits (PDK1)
On are 6 Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) ELISA Kits from 4 different suppliers available. Additionally we are shipping PDK1 Antibodies (141) and PDK1 Proteins (19) and many more products for this protein. A total of 175 PDK1 products are currently listed.
B830012B01, D530020C15Rik, si:zfos-979f1.3
list all ELISA KIts Gene Name GeneID UniProt
Mouse PDK1 PDK1 228026 Q8BFP9
PDK1 5163 Q15118
PDK1 116551  

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Mouse (Murine) Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) interaction partners

  1. PDK1 (show PDPK1 ELISA Kits) plays a pivotal role in regulating cardiac function and tumor metastasis by interfering with microenvironment.

  2. Taken together, our results suggest that LPS (show TLR4 ELISA Kits) induces PDK4 (show PDK4 ELISA Kits) expression and alters glucose metabolism via the JNK (show MAPK8 ELISA Kits) pathway.

  3. hypothesize that PDK1 (show PDPK1 ELISA Kits) plays a significant role in the progression and growth of vascular tumors and targeting PDK1 (show PDPK1 ELISA Kits) may thus be considered in their treatment

  4. PDK1 (show PDPK1 ELISA Kits) ablation promotes epidermal and T-cell mediated dysfunction leading to dermatitis.

  5. T34 phosphorylation by PDK1 (show PDPK1 ELISA Kits) promotes the membrane dissociation of activated Akt (show AKT1 ELISA Kits) for its downstream action through attenuating membrane binding affinity.

  6. These results indicate that PDK1 (show PDPK1 ELISA Kits) participates in the dysregulation of electrophysiological basis by regulating the PDK1 (show PDPK1 ELISA Kits)-Foxo1 (show FOXO1 ELISA Kits) pathway

  7. Our data suggest that two arms of the glucose metabolism synergistically regulate the differential activation of macrophages. Our findings also highlight the central role of PDK1 (show PDPK1 ELISA Kits) in this event via controlling glycolysis and glucose oxidation.

  8. PDHK1 is expressed in Th17 cells, but not Th1 (show HAND1 ELISA Kits) cells, and at low levels in Tregs, and inhibition or knockdown of PDHK1 selectively suppressed Th17 cells and increased Tregs.

  9. Direct genetic evidence for the importance of PDK1 (show PDPK1 ELISA Kits), in part through FOXO3a (show FOXO3 ELISA Kits)-dependent pathway, in melanoma development and progression.

  10. Data show that insulin (show INS ELISA Kits) stimulates GLUT4 (show SLC2A4 ELISA Kits) translocation to the cell surface and iglucose uptake in an Akt1 (show AKT1 ELISA Kits)/2-dependent manner; PI3K phosphorylates Thr308 and Ser473 for Akt1 (show AKT1 ELISA Kits) and Ser474 alone for Akt2 (show AKT2 ELISA Kits); and PDK1 (show PDPK1 ELISA Kits) phosphorylates Thr308 for Akt1 (show AKT1 ELISA Kits) and Akt2 (show AKT2 ELISA Kits).

Human Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) interaction partners

  1. PDK1 was specifically required for metabolic adaptation to nutrient limitation and hypoxia.

  2. High expression of PDK1 is associated with Colon Cancer.

  3. both PDK 1 and 2 isoforms are overexpressed in cutaneous melanoma compared to nevi, this expression being associated with the expression of the mTOR (show FRAP1 ELISA Kits) pathway effectors and independent of the BRAF (show BRAF ELISA Kits) mutational status

  4. Lin28A (show LIN28A ELISA Kits) and Lin28B (show LIN28B ELISA Kits) enhance, whereas let-7 suppresses, aerobic glycolysis via targeting pyruvate dehydrogenase kinase 1, or PDK1.

  5. Follow-up replication analyses in up to an additional 21,345 participants identified three new fasting plasma glucose loci reaching genome-wide significance in or near PDK1-RAPGEF4 (show RAPGEF4 ELISA Kits), KANK1, and IGF1R (show IGF1R ELISA Kits).

  6. NOR1 (show NR4A3 ELISA Kits) expression causes apoptosis of tumor cells in hypoxia by altering the expression of PDK1 expression and mitochondrial Bax (show BAX ELISA Kits)-Bcl2 (show BCL2 ELISA Kits) balance thus suppress tumor cell adaptation to hypoxia

  7. Accordingly, elevated levels of PDK1, PDK3, and PKM2 and reduced PK activity could be observed in iPSCs and human embryonic stem cells in the undifferentiated state

  8. High expression of pyruvate dehydrogenase kinase-1 is associated with gastric cancer.

  9. post-mortem brain extracts from patients with Alzheimer disease exhibited a decrease in PDK1 expression compared with nondemented patients.

  10. Pyruvate dehydrogenase kinase 1 is an important regulator of pyruvate dehydrogenase (show PDP ELISA Kits) in clonal pancreatic beta-cells.

Pig (Porcine) Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) interaction partners

  1. Dephosphorylation of PDK1 may be a molecular switch for enhancement of protein tyrosine phosphorylation and flagellar hyperactivation in boar spermatozoa.

PDK1 Antigen Profile

Antigen Summary

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.

Alternative names and synonyms associated with PDK1

  • pyruvate dehydrogenase kinase, isozyme 1 (PDK1) Elisa Kit
  • pyruvate dehydrogenase kinase, isoenzyme 1 (Pdk1) Elisa Kit
  • pyruvate dehydrogenase kinase, isozyme 1 (Pdk1) Elisa Kit
  • pyruvate dehydrogenase kinase, isozyme 1 (pdk1) Elisa Kit
  • B830012B01 Elisa Kit
  • D530020C15Rik Elisa Kit
  • si:zfos-979f1.3 Elisa Kit

Protein level used designations for PDK1

pyruvate dehydrogenase kinase, isoenzyme 1 , pyruvate dehydrogenase kinase, isozyme 1 , pyruvate dehydrogenase [lipoamide] kinase isozyme 1, mitochondrial-like , PDH kinase 1 , [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial , mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1 , PDK p48 , pyruvate dehydrogenase kinase 1

100218846 Taeniopygia guttata
100402844 Callithrix jacchus
100601990 Nomascus leucogenys
228026 Mus musculus
5163 Homo sapiens
116551 Rattus norvegicus
555840 Danio rerio
425972 Gallus gallus
100286871 Sus scrofa
528655 Bos taurus
476828 Canis lupus familiaris
432080 Xenopus laevis
100064091 Equus caballus
100351323 Oryctolagus cuniculus
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