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PDHX ELISA Kits

(Pyruvate Dehydrogenase Complex, Component X (PDHX))

The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009].

recommended

PDHX ELISA Kit (ABIN6959008)

PDHX Reactivity: Human Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Lysate, Tissue Homogenate

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recommended

PDHX ELISA Kit (ABIN423044)

PDHX Reactivity: Human Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Plasma, Serum

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PDHX ELISA Kits by Reactivity

Find PDHX ELISA Kits for a variety of species such as anti-Human PDHX. The species listed below are among those available. Click on a link to go to the corresponding products.

PDHX ELISA Kits by Detection Method

Find PDHX ELISA Kits with a specific Detection Method. The Detection Method listed below are among those available. Click on a link to go to the corresponding products.

PDHX ELISA Kits by Analytical Method

Find PDHX ELISA Kits with a specific Analytical Method. The Analytical Method listed below are among those available. Click on a link to go to the corresponding products.

PDHX ELISA Kits by Method Type

Find PDHX ELISA Kits with a specific Method Type. The Method Type listed below are among those available. Click on a link to go to the corresponding products.

PDHX ELISA Kits by Sample

Find PDHX ELISA Kits with a specific Sample. The Sample listed below are among those available. Click on a link to go to the corresponding products.

Popular PDHX ELISA Kits

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

PDHX ELISA Kit

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6959008

Quantity 96 tests

Datasheet Datasheet

PDHX ELISA Kit

Reactivity Human

Analytical Method Sandwich ELISA

Validations

Cat. No. ABIN423044

Quantity 96 tests

Datasheet Datasheet

Aliases for PDHX ELISA Kits

pyruvate dehydrogenase complex component X (PDHX) ELISA Kits
pyruvate dehydrogenase complex, component X (Pdhx) ELISA Kits
pyruvate dehydrogenase complex, component X (pdhx) ELISA Kits
pyruvate dehydrogenase complex component X L homeolog (pdhx.L) ELISA Kits
E3-binding protein (pdhX) ELISA Kits
pyruvate dehydrogenase complex component X (pdhx) ELISA Kits
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PDHX ELISA Kits by Reactivity

PDHX ELISA Kits by Detection Method

PDHX ELISA Kits by Analytical Method

PDHX ELISA Kits by Method Type

PDHX ELISA Kits by Sample

Popular PDHX ELISA Kits

Aliases for PDHX ELISA Kits

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