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Browse our anti-PPP2R4 (PPP2R4) Antibodies

Full name:
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 Antibodies (PPP2R4)
On are 69 Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Antibodies from 20 different suppliers available. Additionally we are shipping PPP2R4 Proteins (9) and PPP2R4 Kits (8) and many more products for this protein. A total of 91 PPP2R4 products are currently listed.
2610042B21Rik, 6330556D22Rik, C77440, N28142, PP2A, PR53, PR65, PTPA, PTPRA
list all antibodies Gene Name GeneID UniProt
PPP2R4 51792 Q76MZ3
PPP2R4 5524 Q15257

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anti-Mouse (Murine) PPP2R4 Antibodies:

anti-Human PPP2R4 Antibodies:

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Top referenced anti-PPP2R4 Antibodies

  1. Human Monoclonal PPP2R4 Primary Antibody for ICC, FACS - ABIN969557 : Yoon, Jun, Park, Jun Yoo, Moon, Soon Baik, Kim, Kim, Kim, Koh, Taek Lee, You: Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal. in Stem cells (Dayton, Ohio) 2010 (PubMed)
    Show all 2 references for ABIN969557

  2. Human Monoclonal PPP2R4 Primary Antibody for EIA, FACS - ABIN1108715 : Singh, Ye, Bucur, Zhu, Tanya Santos, Rabinovitz, Wei, Gao, Hahn, Khosravi-Far: Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. in Molecular biology of the cell 2010 (PubMed)
    Show all 2 references for ABIN1108715

  3. Human Polyclonal PPP2R4 Primary Antibody for ChIP, WB - ABIN2668597 : Fellner, Lackner, Hombauer, Piribauer, Mudrak, Zaragoza, Juno, Ogris: A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. in Genes & development 2003 (PubMed)

  4. Cow (Bovine) Polyclonal PPP2R4 Primary Antibody for EIA, WB - ABIN452430 : Gushiken, Patel, Liu, Pradhan, Bergeron, Peng, Vijayan: Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against PPP2R4 Interaction Partners

Mouse (Murine) Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) interaction partners

  1. data indicate that PTPalpha (show PTPRA Antibodies) and FAK (show PTK2 Antibodies), which are enriched in FAs (show FAS Antibodies), interact with IP3R1 (show ITPR1 Antibodies) at adjacent ER sites to spatially sequester IL-1 (show IL1A Antibodies)-induced Ca(2 (show CA2 Antibodies)+) signalling

  2. oocyte-specific deletion of Ppp2r1a (show PPP2R1A Antibodies) led to severe female subfertility without affecting follicle survival, growth, and ovulation.

  3. A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

  4. PP2A (show PPP2R2B Antibodies) (Protein Phosphatase 2A(Twins)) counteracts Plk4 (show PLK4 Antibodies) autophosphorylation, thus stabilizing Plk4 (show PLK4 Antibodies) and promoting centriole duplication

  5. PP2A (show PPP2R2B Antibodies)-A alpha transcriptional regulation is mediated by multiple factors including AP-2alpha (show TFAP2A Antibodies), CREB (show CREB1 Antibodies), ETS-1 (show ETS1 Antibodies), and SP-1 (show SP1 Antibodies)

  6. Data show that DSB promote PP2A to associate with Ku 70 and Ku 86.

  7. findings show that ectopic expression of the phosphotyrosyl phosphatase activator PTPA induces cell death in mammalian cells via a mechanism involving caspase-3 (show CASP3 Antibodies)-dependent apoptosis

  8. oxidative stress regulates the phosphorylation status of nonribosomal rpS3 (show RPS3 Antibodies) by both activating PKCdelta (show PKCd Antibodies) and blocking the PP2A (show PPP2R2B Antibodies) interaction with rpS3 (show RPS3 Antibodies)

  9. protein phosphatase 2A overexpression in NIH 3T3 cells

  10. T-cell receptor (TCR)-dependent tyrosine phosphorylation may be the mechanism by which the regulatory subunit of PP2A (show PPP2R2B Antibodies) prevents the inhibitory function of CTLA-4 (show CTLA4 Antibodies), before TCR-CTLA-4 (show CTLA4 Antibodies) coligation.

Human Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) interaction partners

  1. These results provide direct evidence for the rapid response of PP2A catalytic activity to extracellular insulin (show INS Antibodies) stimulation, as well as insight into the complex regulation of phosphorylation levels by opposing kinase and phosphatase activities within the cell.

  2. LPS (show IRF6 Antibodies) tolerance interferes with TLR4 (show TLR4 Antibodies) signaling by inhibiting Lyn (show LYN Antibodies) and c-Src (show SRC Antibodies) phosphorylation and their recruitment to TLR4 (show TLR4 Antibodies), while increasing the phosphatase activity and expression of PP2A, PTPN22 (show PTPN22 Antibodies), PTP1B (show PTPN1 Antibodies) and MKP1 (show DUSP1 Antibodies).

  3. we propose that RhoB could be responsible for early metastatic prevention by inhibiting the EMT (show ITK Antibodies)-derived invasiveness of lung cells through the control of PP2A activity.

  4. Cohesin complex (show SMC3 Antibodies) is shown to be a target of the prophase pathway at centrosomes and protected by Sgo1 (show SGOL1 Antibodies)-dependent PP2A recruitment.

  5. Zinc-alpha2-glycoprotein modulates AKT (show AKT1 Antibodies)-dependent insulin (show INS Antibodies) signaling in adipocytes by activation of the PP2A phosphatase.

  6. these data reveal the molecular mechanisms of PP2A regulation and highlight the potential of boosting the power of endogenous phosphatases as novel anti-inflammatory strategies to combat asthmatic inflammation.

  7. Transgenic overexpression of myocardial PP2A causes adverse remodeling which coincides with a disruption of the classical Akt (show AKT1 Antibodies)/GSK3/beta (show GSK3b Antibodies)-catenin (show CTNNB1 Antibodies) pathway under baseline conditions that is restored to normal values in chronic myocardial infarction.

  8. an increase in the phosphorylation level of PTPalphaTyr789 by its upstream activator, FAKDel33, leading to Src (show SRC Antibodies) activation in certain breast cancer cells, which has significant implications for metastatic potential.

  9. results suggested that PPFIA1 (show PPFIA1 Antibodies) functioned with PP2A to promote the dephosphorylation of Kif7 (show KIF7 Antibodies), triggering Kif7 (show KIF7 Antibodies) localization to the tips of primary cilia and promoting Gli (show GLI1 Antibodies) transcriptional activity.

  10. The roles of protein phosphatases including MAPK phosphatase-1 (MKP-1 (show DUSP1 Antibodies)) and protein phosphatase type 2A (PP2A) in modulating p38MAPK (show MAPK14 Antibodies) activation and downstream TNF-alpha (show TNF Antibodies) expressions in primary human monocyte-derived macrophages, were examined.

PPP2R4 Antigen Profile

Antigen Summary

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PPP2R4

  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a) antibody
  • protein phosphatase 2A activator, regulatory subunit 4 (PPP2R4) antibody
  • protein phosphatase 2A, regulatory subunit B (PR 53) (Ppp2r4) antibody
  • 2610042B21Rik antibody
  • 6330556D22Rik antibody
  • C77440 antibody
  • N28142 antibody
  • PP2A antibody
  • PR53 antibody
  • PR65 antibody
  • PTPA antibody
  • PTPRA antibody

Protein level used designations for PPP2R4

PP2A subunit A isoform PR65-alpha , PP2A subunit A isoform R1-alpha , protein phosphatase PP2A , serine/threonine protein phosphatase A subunit type 2A , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform , PP2A phosphatase activator , PP2A subunit B' isoform PR53 , phosphotyrosyl phosphatase activator , protein phosphatase 2A, regulatory subunit B' (PR 53) , serine/threonine-protein phosphatase 2A activator , serine/threonine-protein phosphatase 2A regulatory subunit B' , PP2A, subunit B', PR53 isoform , PTPA , serine/threonine-protein phosphatase 2A regulatory subunit 4 , protein tyrosine phosphatase, receptor type, A

51792 Mus musculus
5524 Homo sapiens
514460 Bos taurus
100009404 Oryctolagus cuniculus
110854 Mus musculus
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