PPP2R4 antibody (AA 1-250)
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- Target See all PPP2R4 Antibodies
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
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Binding Specificity
- AA 1-250
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPP2R4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Serine/threonine-protein phosphatase 2A activator protein (1-250AA)
- Isotype
- IgG
- Top Product
- Discover our top product PPP2R4 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
- Alternative Name
- PTPA (PPP2R4 Products)
- Synonyms
- PP2A antibody, PR53 antibody, PTPA antibody, 2610042B21Rik antibody, C77440 antibody, N28142 antibody, PTPRA antibody, Ppp2r4 antibody, fc23d07 antibody, ppp2r4 antibody, wu:fc23d07 antibody, zgc:92766 antibody, pp2a antibody, ppp2r4.L antibody, pr53 antibody, ptpa antibody, protein phosphatase 2 phosphatase activator antibody, protein phosphatase 2 protein activator antibody, protein phosphatase 2 phosphatase activator L homeolog antibody, PTPA antibody, Ptpa antibody, ptpa antibody, ptpa.L antibody
- Background
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Background: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis, the function appears to be independent from PP2A.
Aliases: subunit B'' antibody, KIAA0044 antibody, MGC2184 antibody, Phosphotyrosyl phosphatase activator antibody, PP2A antibody, PP2A phosphatase activator antibody, PP2A subunit B' antibody, PP2A subunit B' isoform PR53 antibody, PP2A subunit B' PR53 isoform antibody, PPP2R4 antibody, PR53 antibody, PR53 isoform antibody, Protein phosphatase 2, regulatory subunit B-prime antibody, Protein phosphatase 2A activator regulatory subunit 4 antibody, Protein phosphatase 2A regulatory subunit B' (PR 53) antibody, PTPA antibody, PTPA_HUMAN antibody, Serine/threonine protein phosphatase 2A regulatory subunit B' antibody, Serine/threonine-protein phosphatase 2A activator antibody, Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody, Serine/threonine-protein phosphatase 2A regulatory subunit B'' antibody
- UniProt
- Q15257
- Pathways
- PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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