PPP2R4 antibody (Center)
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- Target See all PPP2R4 Antibodies
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPP2R4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Chicken, Rabbit, Rat (Rattus), Zebrafish (Danio rerio), Cow (Bovine)
- Cross-Reactivity (Details)
- Chicken (94 %), Rabbit (96 %), Rat (94 %), Zebrafish (83 %), Bovine (98 %)
- Characteristics
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Rabbit Polyclonal antibody to PPP2R4 (protein phosphatase 2A activator, regulatory subunit 4)
PPP2R4 antibody [N2C3] - Purification
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human PPP2R4. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product PPP2R4 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: 293T , A431 , mouse brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 6.31 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
- Alternative Name
- PPP2R4 (PPP2R4 Products)
- Synonyms
- PP2A antibody, PR53 antibody, PTPA antibody, 2610042B21Rik antibody, C77440 antibody, N28142 antibody, PTPRA antibody, Ppp2r4 antibody, fc23d07 antibody, ppp2r4 antibody, wu:fc23d07 antibody, zgc:92766 antibody, pp2a antibody, ppp2r4.L antibody, pr53 antibody, ptpa antibody, protein phosphatase 2 phosphatase activator antibody, protein phosphatase 2 protein activator antibody, protein phosphatase 2 phosphatase activator L homeolog antibody, PTPA antibody, Ptpa antibody, ptpa antibody, ptpa.L antibody
- Background
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Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 41 kDa
- Gene ID
- 5524
- Pathways
- PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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