Browse our anti-Tumor Necrosis Factor (TNF) Antibodies

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anti-Tumor Necrosis Factor Antibodies (TNF)
On are 1709 Tumor Necrosis Factor (TNF) Antibodies from 52 different suppliers available. Additionally we are shipping Tumor Necrosis Factor Kits (318) and Tumor Necrosis Factor Proteins (258) and many more products for this protein. A total of 2322 Tumor Necrosis Factor products are currently listed.
Cachectin, cTNF, DIF, RATTNF, tnf, TNF-a, Tnf-alpha, TNFa, tnfa-like, TNFalpha, Tnfsf1a, TNFSF2, xtnf
list all antibodies Gene Name GeneID UniProt
TNF 7124 P01375
TNF 21926 P06804
Anti-Rat TNF TNF 24835 P16599

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All available anti-Tumor Necrosis Factor Antibodies

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Top referenced anti-Tumor Necrosis Factor Antibodies

  1. Human Polyclonal Tumor Necrosis Factor Primary Antibody for ICC, IF - ABIN446837 : Kwon, Jung, Hwang, Choi: Evaluation of Bronchiolar and Alveolar Cell Injuries Induced by Short- and Long-term Exposure to Sidestream Smoke. in Korean journal of pathology 2012 (PubMed)
    Show all 11 references for 446837

  2. Human Polyclonal Tumor Necrosis Factor Primary Antibody for IF (p), IHC (p) - ABIN677318 : Morishita, Oku, Horie, Tonari, Kida, Okubo, Sugiyama, Takai, Hara, Ikeda: Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-?B activation. in PLoS ONE 2014 (PubMed)
    Show all 10 references for 677318

  3. Cow (Bovine) Monoclonal Tumor Necrosis Factor Primary Antibody for EIA, FACS - ABIN120182 : Hope, Whelan, Hewinson, Vordermeier, Howard: Maturation of bovine dendritic cells by lipopeptides. in Veterinary immunology and immunopathology 2003 (PubMed)
    Show all 4 references for 120182

  4. Human Polyclonal Tumor Necrosis Factor Primary Antibody for IF, IHC (p) - ABIN498271 : Chae, Park, Hwang, Kwon, Lim, Yi, Han, Kim, Baek: The effect of antioxidants on the production of pro-inflammatory cytokines and orthodontic tooth movement. in Molecules and cells 2011 (PubMed)
    Show all 2 references for 498271

  5. Baboon Monoclonal Tumor Necrosis Factor Primary Antibody for ELISA, FACS - ABIN263068 : Bimpis, Papalois, Voumvourakis, Oláh, Tiszlavicz, Liapi: Neuronal tumour necrosis factor-α and interleukin-1β expression in a porcine model of intracerebral haemorrhage: Modulation by U-74389G. in Brain research 2015 (PubMed)

  6. Human Monoclonal Tumor Necrosis Factor Primary Antibody for CC, ELISA - ABIN1997163 : Cohen, Sabhachandani, Golberg, Konry: Approaching near real-time biosensing: microfluidic microsphere based biosensor for real-time analyte detection. in Biosensors & bioelectronics 2014 (PubMed)

  7. Baboon Monoclonal Tumor Necrosis Factor Primary Antibody for ICC, FACS - ABIN263069 : Baker, Murphy, Lopez, Garcia: Conversion of a capture ELISA to a Luminex xMAP assay using a multiplex antibody screening method. in Journal of visualized experiments : JoVE 2012 (PubMed)

  8. Human Monoclonal Tumor Necrosis Factor Primary Antibody for FACS - ABIN1109411 : Arduise, Abache, Li, Billard, Chabanon, Ludwig, Mauduit, Boucheix, Rubinstein, Le Naour: Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

  9. Human Monoclonal Tumor Necrosis Factor Primary Antibody for EIA, FACS - ABIN118949 : Bebök, Márkus, Németh: Prognostic relevance of transforming growth factor alpha (TGF-alpha) and tumor necrosis factor alpha (TNF-alpha) detected in breast cancer tissues by immunohistochemistry. in Breast cancer research and treatment 1994 (PubMed)

  10. Human Monoclonal Tumor Necrosis Factor Primary Antibody for IF (p), IHC (p) - ABIN722481 : Zhang, Zha, Ye, Wang, Wang, Shen, Wu, Zhu: Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice. in Journal of applied toxicology : JAT 2015 (PubMed)

More Antibodies against Tumor Necrosis Factor Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Tumor Necrosis Factor (TNF) interaction partners

  1. Our findings demonstrate that TNF-alpha plays a pivotal role in HF-mediated neuroinflammation and associated alterations of cortical dendritic spine density and has the potential to reveal novel treatment strategies for HF-associated memory deficits.

  2. the present study assessed the combined impacts of estrogens and bacterial infection on the insulin (show INS Antibodies)-like growth factors (IGF) and tumor-necrosis factor (TNF)-alpha.

  3. The expression of miR (show MYLIP Antibodies)-125b-1 regulated by NF-kappaB (show NFKB1 Antibodies) has been reported in diverse cell types under various stimuli, this study found that its expression was also significantly regulated by NF-kappaB (show NFKB1 Antibodies) in TNFalpha-stimulated HeLa and HepG2 cells

  4. In the Han Chinese population, the allele 'A' of TNF-alpha -308 may increase the risk for osteoarthritis (OA), whereas TNF-alpha -238 polymorphisms do not play a role in OA patients.

  5. Letter: serum TNF-alpha was not elevated in chronic spontaneous urticaria.

  6. Metastatic cells can escape the proapoptotic effects of TNF-alpha through increased autocrine IL-6 (show IL6 Antibodies)/STAT3 (show STAT3 Antibodies) signaling

  7. The predicted 3D structures of IL-1beta (show IL1B Antibodies), TNF-alpha, and IL-8 (show IL8 Antibodies) from Oncorhynchus mykiss, Dicentrarchus labrax, and Chionodraco hamatus are reported and the differences between them and their mammalian counterparts investigated.

  8. The mitochondrial dysfunction may be caused by increased brain levels of TNFalpha without physiological stress but will be exacerbated after middle cerebral artery occlusion.

  9. TNF-alpha is released rapidly in trout macrophages after stimulation with lipopolysaccharide and zymosan, and its secretion is dependent on TACE (show ADAM17 Antibodies)-like activity that is regulated by ERK (show MAPK1 Antibodies), JNK (show MAPK8 Antibodies) and p38MAPK (show MAPK14 Antibodies) signaling pathways.

  10. Recombinant, as well as native trout TNF-alpha, directly stimulates glucose uptake in trout muscle cells and provide evidence, for the first time in nonmammalian vertebrates, for a potential regulatory role of TNF-alpha in skeletal muscle metabolism.

Human Tumor Necrosis Factor (TNF) interaction partners

  1. Double electron-electron resonance in conjunction with site-directed spin labeling has been used to probe natural conformational sampling of the human tumor necrosis factor alpha trimer. We suggest a previously unreported, predeoligomerization conformation of the trimer that has been shown to be sampled at low frequency.

  2. This study showed no associations between TNFA -308G/A or -857C/T and Guillain-Barre syndrome, subtype or severity.

  3. Overall, these results suggest that GILZ (show TSC22D3 Antibodies) antagonizes the pro-inflammatory effects of TNFa in human adipocytes, and its downregulation in obesity may contribute to adipose inflammation and dysregulated adipokine production, and thereby systemic metabolism.

  4. The allelic frequencies of TNFA SNPs were found to be significantly associated with the risk of oral cancer and precancerous lesions

  5. Hyaluronan synthase 3 (HAS3 (show HAS3 Antibodies)) and tumor necrosis factor-alpha (TNF-alpha) formed an inter-regulation loop to enhance tumorigenesis in oral cancer.

  6. Inhibition of the inflammatory signaling intermediate p38 MAPK (show MAPK14 Antibodies) reduced tissue factor (show F3 Antibodies) (TF) mRNA by one third but increased tumor necrosis factor (TNF) and interleukin-1 beta (IL-1beta (show IL1B Antibodies)) mRNA.

  7. Data suggest the highest serum levels of auto-antibodies against monomeric C-reactive protein (show CRP Antibodies) (mCRP) are observed in patients with lupus nephritis, as compared to patients with primary glomerulonephritis or control subjects; IL6 (interleukin-6 (show IL6 Antibodies)) and TNFA (tumor necrosis factor-alpha) are also elevated in serum of patients with lupus nephritis; these 3 biomarkers decrease with treatment. This study was conducted in Poland.

  8. Using a human oligodendroglioma (HOG (show MAPK14 Antibodies)) cell line as a model, here we show that exosomes derived from TNF-a-treated "donor" cells, while being mildly toxic to fresh cultures (similar to individual cytokines), induce enhanced cell death when added to IFN-g (show IFNG Antibodies)-primed target cultures in a fashion resembling the effect of cytokine combination

  9. polymorphisms of the TNF-alpha gene had different plasma fatty acid profiles and inflammatory biomarkers between genotypes; -308G/A interacts with plasma stearic acid and total serum fatty acids, whereas -857C/T interacts with plasma alpha-linolenic acid, modifying the association with inflammatory profile

  10. Meta-analysis: TNF-alpha -308 G/A polymorphism was associated with an increased risk of COPD (show ARCN1 Antibodies) among Asians but not in non-Asians. Furthermore, individuals with the AA genotype of TNF-alpha -308 were more susceptible to developing COPD (show ARCN1 Antibodies).

Mouse (Murine) Tumor Necrosis Factor (TNF) interaction partners

  1. Our study suggests that additionally to its local actions in the AD brain, TNF-alpha can also indirectly modulate amyloid pathology as a regulator of peripheral inflammation.

  2. cell-autonomous role of TNF on monocytes for their survival, maintenance, and function.

  3. Neutralizing low TNFalpha levels in the tumor microenvironment sensitizes breast tumor cells to paclitaxel.

  4. data show that Fyn (show FYN Antibodies) kinase is activated after TLR4 (show TLR4 Antibodies) triggering and exerts an important negative control on LPS (show TLR4 Antibodies)-dependent TNF production in mast cells controlling the inactivation of PP2Ac (show PPP2CA Antibodies) and activation of PKCalpha (show PKCa Antibodies)/beta necessary for the secretion of TNF by VAMP3 (show VAMP3 Antibodies)(+) carriers

  5. TNF-alpha is up-regulated in bilateral hippocampus and in ipsilateral spinal dorsal horn after peripheral nerve injury.

  6. miR (show MLXIP Antibodies)-124, targeting USP2 (show USP2 Antibodies) and USP14 (show USP14 Antibodies), negatively regulates LPS (show TLR4 Antibodies)-induced TNF-alpha production in mouse macrophages, suggesting miR (show MLXIP Antibodies)-124 as a new therapeutic target in inflammation-related diseases

  7. XIAP (show XIAP Antibodies) antagonizes the switch from TNFalpha-induced apoptosis to necroptosis in mouse neutrophils.

  8. demonstrated a central role for macrophages, TNF-alpha, and MCP-1 (show CPT1B Antibodies) in the pathogenesis of respiratory syncytial virus-induced exacerbation of airway hyperresponsiveness and inflammation in mice with allergic airways disease

  9. These experiments reveal an essential role for TNF activation of NF-kappaB (show NFKB1 Antibodies) to promote the survival and development of single positive T cells in the thymus.

  10. In SOD1 (show SOD1 Antibodies)(G93A) spinal cords, we verified a strict correlation in the expression of the TNFalpha, TNFR1 (show TNFRSF1A Antibodies) and GDNF (show GDNF Antibodies) triad at different stages of disease progression. Yet, ablation of TNFR1 (show TNFRSF1A Antibodies) completely abolished GDNF (show GDNF Antibodies) rises in both SOD1 (show SOD1 Antibodies)(G93A) astrocytes and spinal cords, a condition that accelerated motor neuron degeneration (show CLN8 Antibodies) and disease progression

Pig (Porcine) Tumor Necrosis Factor (TNF) interaction partners

  1. TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (show PDCD4 Antibodies)/NF-kappaB (show NFKB1 Antibodies)/ TNF-alpha pathway in cardiomyocytes.

  2. TNF-alpha, secreted from activated Monocytes, mediates the downregulation of OTX2 (show OTX2 Antibodies) and essential retinal pigment epithelium genes.

  3. TNF-alpha induced MMP-13 (show MMP13 Antibodies) expression by condylar cells might be involved in the degradation of the juvenile condyle.

  4. TNF-alpha was able to promote theca interna cell proliferation. Our results suggest that TNF-alpha might play a role in hyperandrogenism, cortex thickness, and the increased ovary volume observed in polycystic ovaries.

  5. This study showed that the -791(C-->T) mutation of the TNF-alpha gene could be considered an important potential genetic marker of enterotoxigenic Escherichia coli F18 (show MAMLD1 Antibodies) resistance.

  6. Both Nsp1beta and Nsp11 of porcine reproductive and respiratory syndrome virus were demonstrated to be responsible for the inhibitory effect on TNF-alpha production in pulmonary alveolar macrophages.

  7. Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (show IL1B Antibodies), IL-8 (show IL8 Antibodies) and TNF-alpha in porcine alveolar macrophages.

  8. the role of miR (show MYLIP Antibodies)-181a in adipocyte differentiation by regulation of TNF-alpha

  9. The NOS (show NOS Antibodies) inhibitor, L-NMMA, significantly suppressed the combined effects of HT and CORM-2 on TNFalpha-triggered NFkappaBp65 phosphorylation as well as decreased cell viability.

  10. High-volume hemofiltration improves hemodynamics and heart dysfunction in septic shock pigs, which may be attributed to reduction of TNF-alpha in myocardium but not in circulation.

Cow (Bovine) Tumor Necrosis Factor (TNF) interaction partners

  1. Data suggest that luteolytic factors (such as TNFa, interferon gamma (show IFNG Antibodies), and PGF2a) control expression of MMP1 (show MMP1 Antibodies), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  2. These results suggest that polymorphism of the TNFalpha-824 A>G gene and mTNFalpha protein expression play an important role in the pathogenesis of enzootic bovine leukosis.

  3. These results suggest that the endometrium might lower the TNF concentration in the blastocyst by (1) regulating TNF secretion into the uterine fluid and (2) inducing decreased TNF and TNFR2 (show TNFRSF1B Antibodies) mRNA transcription in the embryo.

  4. There was a significant association between the proviral load and a low frequency of the G/G genotype of TNF-alpha at position -824.

  5. SNP in the TNF-alpha gene affects immune function and reproductive performance in dairy cows.

  6. Studied genotypic and expression profiling of partial TNF-alpha gene and its association with mastitis susceptibility in 129 crossbred cattle.

  7. Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (show PTGES Antibodies)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF) and Fas (show FAS Antibodies) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.

  8. TNF-alpha up-regulates NaV1.7 (show SCN9A Antibodies) mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha

  9. These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha and iNOS (show NOS2 Antibodies) pathways in the regulation of this pathological condition.

  10. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.

Horse (Equine) Tumor Necrosis Factor (TNF) interaction partners

  1. The results obtained showed that IL-6 (show IL6 Antibodies) expression in adipose tissue biopsies derived from animals with equine metabolic syndrome was enhanced while TNF-alpha levels of both groups were comparable.

  2. Data indicate that tumor necrosis factor-alpha production is closely related to ovarian steroid actions.

  3. These results indicate that in equine corpus luteum, cytokines TNF, IFNG (show IFNG Antibodies) and FASL (show FASL Antibodies) regulate nitric oxide activity, via eNOS (show NOS3 Antibodies) expression modulation.

  4. These data show the presence of cytokines TNF and IFNG (show IFNG Antibodies), and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.

  5. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Antibodies), IL-10 (show IL10 Antibodies) and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Rabbit Tumor Necrosis Factor (TNF) interaction partners

  1. TUNEL staining was positively correlated with TNF-a protein expression. Our findings suggest that apoptosis can be induced in the vocal fold epithelium after 120min of modal intensity phonation. In contrast, shorter durations of vibration exposure do not result in apoptosis signaling.

  2. Inflammatory factors such as TNF-alpha can stimulate MMP-2 (show MMP2 Antibodies)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases.

  3. The JNK (show MAPK8 Antibodies) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha expression in alveolar macrophages, but the injury-stimulated IL-8 (show IL8 Antibodies) expression may be regulated by other signaling pathways.

  4. The TNFalpha-evoked Cl- current.

  5. IL-1beta (show IL1B Antibodies) and TNF-alpha expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta (show IL1B Antibodies) and TNF-alpha.

  6. Hypercapnia increased expression of TNFa and decreased expression of NFKB in acute lung injury models.

  7. In the early stages of myocardial ischemia, bone marrow stem cells are mobilized and home to ischemic myocardium with a concomitant increase in expression of cytokines VEGF (show VEGFA Antibodies) and TNFalpha.

  8. Ammonium perchlorate can increase gene expressions of types I, III collagens, TGF-beta(1 (show TGFB1 Antibodies)) and TNF-alpha in lung of rabbits.

  9. TNFalpha may either be directly or indirectly involved in vascular damage following an embolic stroke. Moreover, TNFalpha may mediate some of the detrimental effects of tPA (show PLAT Antibodies) on the vascular compartment

Rhesus Monkey Tumor Necrosis Factor (TNF) interaction partners

  1. These interactions result in the induction of the TNF signaling pathway, activation of apoptosis, and DNA-damage stress response.

  2. Findings showed that both mucosal compartments harbor similar percentages of memory CD4 (show CD4 Antibodies)(+) T cells and displayed comparable cytokine TNF-alpha responses to mitogenic stimulations prior to infection.

  3. Primary role for IL-1beta (show IL1B Antibodies) and TNF-alpha in the triggering of preterm labor associated with inflammation or infection.

Goat Tumor Necrosis Factor (TNF) interaction partners

  1. Data indicate that three single-nucleotide polymorphisms were identified in tumor necrosis factor-alpha (TNF-alpha) gene.

Zebrafish Tumor Necrosis Factor (TNF) interaction partners

  1. The results reveal a crucial role for TNFalpha/TNFR2 (show TNFRSF1B Antibodies) axis in the protection of the skin against DUOX1 (show DUOX1 Antibodies)-mediated oxidative stress.

  2. TNF alpha is the first molecule identified that is produced by dying retinal neurons and is necessary to induce Muller glia to proliferate in the zebrafish retinal regeneration response.

  3. The data suggest that Mycobacterium marinum SecA2 modulates adaptive immunity to promote granuloma stability, perhaps through induction of tumor necrosis factor alpha.

  4. TNF is not required for tuberculous granuloma formation, but maintains granuloma integrity indirectly by restricting mycobacterial growth within macrophages and preventing their necrosis.

  5. The main proinflammatory effects of fish TNF-alpha are mediated through the activation of endothelial cells and point to the complexity of the evolution that has taken place in the regulation of innate immunity by cytokines.

Tumor Necrosis Factor (TNF) Antigen Profile

Antigen Summary

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Alternative names and synonyms associated with Tumor Necrosis Factor (TNF)

  • tumor necrosis factor (TNF superfamily, member 2) (TNF) antibody
  • tumor necrosis factor (tnf) antibody
  • tumour necrosis factor alpha-like (tnf-alpha) antibody
  • tumor necrosis factor alpha (tnf-alpha) antibody
  • lipopolysaccharide-induced TNF factor (LITAF) antibody
  • tumor necrosis factor (TNF) antibody
  • tumor necrosis factor (Tnf) antibody
  • tumor necrosis factor alpha (TNF) antibody
  • tumor necrosis factor b (TNF superfamily, member 2) (tnfb) antibody
  • Cachectin antibody
  • cTNF antibody
  • DIF antibody
  • RATTNF antibody
  • tnf antibody
  • TNF-a antibody
  • Tnf-alpha antibody
  • TNFa antibody
  • tnfa-like antibody
  • TNFalpha antibody
  • Tnfsf1a antibody
  • TNFSF2 antibody
  • xtnf antibody

Protein level used designations for TNF

tumor necrosis factor (TNF superfamily, member 2) , tumor necrosis factor alpha , tumor necrosis factor , tumour necrosis factor alpha , putative tumour necrosis factor alpha , LPS-induced TNF-alpha factor homolog , TNF-alpha factor , lipid-induced TNF-alpha factor , lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog , small integral membrane protein of lysosome/late endosome , tissue necrosis factor-alpha , APC1 protein , TNF, macrophage-derived , TNF, monocyte-derived , TNF-a , cachectin , tumor necrosis factor ligand superfamily member 2 , tumor necrosis factor-alpha , TNF-alpha , tumor-necrosis factor , tumour necrosis factor , ATP-binding cassette, sub-family F (GCN20), member 1 , TNF alpha , tumor necrosis factor, alpha , TNF2 , lta

744399 Pan troglodytes
100136064 Oncorhynchus mykiss
100304592 Ictalurus punctatus
100134991 Xenopus (Silurana) tropicalis
100136034 Oncorhynchus mykiss
100137091 Salmo salar
374125 Gallus gallus
7124 Homo sapiens
21926 Mus musculus
24835 Rattus norvegicus
397086 Sus scrofa
280943 Bos taurus
443540 Ovis aries
100033834 Equus caballus
403922 Canis lupus familiaris
100135630 Cavia porcellus
100009088 Oryctolagus cuniculus
493755 Felis catus
715467 Macaca mulatta
100397484 Callithrix jacchus
101420445 Dasypus novemcinctus
494186 Pan troglodytes
101318178 Tursiops truncatus
100861232 Capra hircus
554167 Danio rerio
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