Browse our anti-GIPR (GIPR) Antibodies

Full name:
anti-Gastric Inhibitory Polypeptide Receptor Antibodies (GIPR)
On www.antibodies-online.com are 179 Gastric Inhibitory Polypeptide Receptor (GIPR) Antibodies from 17 different suppliers available. Additionally we are shipping GIPR Kits (5) and GIPR Proteins (4) and many more products for this protein. A total of 194 GIPR products are currently listed.
Synonyms:
GIP-R, Gippr, GIPR, Gm160, Gm1081, PGQTL2, RATGIPPR

Most Popular Reactivities for anti-GIPR (GIPR) Antibodies

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anti-Human GIPR Antibodies:

anti-Mouse (Murine) GIPR Antibodies:

anti-Rat (Rattus) GIPR Antibodies:

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Top referenced anti-GIPR Antibodies

  1. Human Polyclonal GIPR Primary Antibody for IHC (p) - ABIN4314158 : Snook, Nelson, Dyck, Wright, Holloway: Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle. in American journal of physiology. Regulatory, integrative and comparative physiology 2015 (PubMed)
    Show all 3 references for 4314158

  2. Human Polyclonal GIPR Primary Antibody for FACS, IHC (p) - ABIN391714 : Ugleholdt, Pedersen, Bassi, Füchtbauer, Jørgensen, Kissow, Nytofte, Poulsen, Rosenkilde, Seino, Thams, Holst, Holst: Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain. in The Journal of biological chemistry 2011 (PubMed)

  3. Cow (Bovine) Polyclonal GIPR Primary Antibody for IHC (p) - ABIN4314159 : Figueiredo, Antunes, Moreira, de Mello, Medeiros, Di Giunta, Lobão-Soares, Linhares, Lin, Mazzuco, Prediger, Walz: Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus. in Peptides 2011 (PubMed)

  4. Human Polyclonal GIPR Primary Antibody for IHC (p) - ABIN270972 : Prasadan, Koizumi, Tulachan, Shiota, Lath, Paredes, Guo, El-Gohary, Malek, Shah, Gittes: The expression and function of glucose-dependent insulinotropic polypeptide in the embryonic mouse pancreas. in Diabetes 2011 (PubMed)

More Antibodies against GIPR Interaction Partners

Human Gastric Inhibitory Polypeptide Receptor (GIPR) interaction partners

  1. Data suggest that GIPR (gastric inhibitory polypeptide receptor) is among the few GPCRs (G-protein-coupled receptors) which signal through G-proteins (GTP-binding protein Gs alpha subunit (show GNAS Antibodies), here) both at plasma membrane and in endosomes; recombinant proteins expressed in HEK293 cells were used in these studies.

  2. GIPR overexpression does not appear to affect acromegalic patients' clinical features

  3. Study shows the internalization of GIPR involving clathrin-coated pits, AP-2 (show GTF3A Antibodies) and dynamin (show DNM1 Antibodies) and its subsequent intracellular trafficking. GIP (show GIP Antibodies) stimulates a rapid robust internalization of the GIPR, the major part being directed to lysosomes.

  4. The common variant rs10423928 in the GIPR gene is associated with increased risk of stroke in patients with type 2 diabetes.

  5. Body mass index change for the A/T+A/A in GIPR genotypes was significantly higher than that for the T/T genotype. rs10423928 may predict weight gain in schizophrenia.

  6. The potential future role of gastric inhibitory peptide (GIP (show GIP Antibodies)) receptors as molecular targets in neuroendocrine neoplasms may be dependent on the tumor grade.

  7. Results show that GIPR undergoes trafficking between the plasma membrane and intracellular compartments of both GIP (show GIP Antibodies)-stimulated and unstimulated adipocytes.

  8. GIPR is overexpressed in gastric and duodenal neuroendocrine tumors

  9. GIPR expression was downregulated in subcutaneous adipose tissue from obese patients and correlated negatively with body mass index, waist circumference, systolic blood pressure, and glucose and triglyceride levels.

  10. GIPR promoter was hypomethylated in type 2 diabetic patients as compared to controls.

Mouse (Murine) Gastric Inhibitory Polypeptide Receptor (GIPR) interaction partners

  1. GIPR signaling in adipose tissue plays a critical role in high fat diet-induced insulin (show INS Antibodies) resistance and hepatic steatosis in vivo, which may involve IL-6 (show IL6 Antibodies) signaling.

  2. Genetic deletion of both GLP-1 (show GCG Antibodies) and GIP (show GIP Antibodies) receptors reveals that they are required to maintain an adequate islet number in adulthood and to maintain normal beta cell responses to glucose.

  3. Results suggest the beneficial effects of glucose-dependent insulinotropic polypeptide (show GIP Antibodies) on periodontal disease.

  4. Gipr(-/-) offspring of mice exposed to high fat diet(HFD) during pregnancy/lactation became insulin (show INS Antibodies) resistant and obese and exhibited increased adipose tissue inflammation and decreased peripheral tissue substrate utilization after reintroduction of HFD.

  5. Beta-cell Gipr KO mice exhibit lower levels of meal-stimulated insulin (show INS Antibodies) secretion, decreased expansion of adipose tissue mass and preservation of insulin (show INS Antibodies) sensitivity and decreased TCF1 (show HNF1A Antibodies) expression.

  6. Gipr is expressed in healthy arteries, predominantly in endothelial cells.

  7. These data highlighted the importance of intact GIPR signalling and dietary composition in modulating memory and learning, and hippocampal pathways involved in the maintenance of synaptic plasticity

  8. Functional GIP (show GIP Antibodies) receptors play a major role in islet compensatory response to high fat feeding in mice.

  9. our data demonstrate that the expression of GLP-1R (show GLP1R Antibodies) and GIPR is regulated by glucose (show ZNF236 Antibodies) concentrations in MC3T3-E1 cells undergoing differentiation induced by BMP-2 (show BMP2 Antibodies).

  10. Results show that GIPR undergoes trafficking between the plasma membrane and intracellular compartments of both GIP (show GIP Antibodies)-stimulated and unstimulated adipocytes.

Golden Syrian Hamster Gastric Inhibitory Polypeptide Receptor (GIPR) interaction partners

  1. Data suggest that high levels of blood glucose or AGEs (advanced glycation end products), as seen in hyperglycemia, reduce secretion of insulin (show INS Antibodies) by pancreatic beta cells via antagonism of GIP (gastric inhibitory polypeptide (show GIP Antibodies))/GIP (show GIP Antibodies) receptor signaling.

GIPR Antigen Profile

Antigen Summary

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

Alternative names and synonyms associated with GIPR

  • gastric inhibitory polypeptide receptor (GIPR) antibody
  • gastric inhibitory polypeptide receptor (LOC100350463) antibody
  • gastric inhibitory polypeptide receptor (Gipr) antibody
  • GIP-R antibody
  • Gippr antibody
  • GIPR antibody
  • Gm160 antibody
  • Gm1081 antibody
  • PGQTL2 antibody
  • RATGIPPR antibody

Protein level used designations for GIPR

gastric inhibitory polypeptide receptor , glucagon receptor , gastric inhibitory polypeptide receptor-like , GIP-R , glucose-dependent insulinotropic polypeptide receptor , gastric inhibitory peptide receptor

GENE ID SPECIES
100170666 Ovis aries
100303705 Meleagris gallopavo
745427 Pan troglodytes
484439 Canis lupus familiaris
100350463 Oryctolagus cuniculus
100410438 Callithrix jacchus
100432362 Pongo abelii
2696 Homo sapiens
381853 Mus musculus
25024 Rattus norvegicus
101844713 Mesocricetus auratus
617879 Bos taurus
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