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Human CD27 Protein expressed in Human Cells - ABIN2001942
Borst, Hendriks, Xiao: CD27 and CD70 in T cell and B cell activation. in Current opinion in immunology 2005
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Human CD27 Protein expressed in Baculovirus infected Insect Cells - ABIN2001940
Kobata, Jacquot, Kozlowski, Agematsu, Schlossman, Morimoto: CD27-CD70 interactions regulate B-cell activation by T cells. in Proceedings of the National Academy of Sciences of the United States of America 1995
Show all 5 references for ABIN2001940
Rhesus Monkey CD27 Protein expressed in Human Cells - ABIN2009771
Jacquot: CD27/CD70 interactions regulate T dependent B cell differentiation. in Immunologic research 2000
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Mouse (Murine) CD27 Protein expressed in Human Cells - ABIN2007336
Arens, Nolte, Tesselaar, Heemskerk, Reedquist, van Lier, van Oers: Signaling through CD70 regulates B cell activation and IgG production. in Journal of immunology (Baltimore, Md. : 1950) 2004
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Human CD27 Protein expressed in HEK-293 Cells - ABIN2180735
Zhang, Henzel: Signal peptide prediction based on analysis of experimentally verified cleavage sites. in Protein science : a publication of the Protein Society 2004
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Human CD27 Protein expressed in Escherichia coli (E. coli) - ABIN1098678
Gravestein, Amsen, Boes, Calvo, Kruisbeek, Borst: The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2. in European journal of immunology 1998
Show all 2 references for ABIN1098678
Human CD27 Protein expressed in Wheat germ - ABIN1348589
Yoshino, Kishibe, Nagato, Ueda, Komabayashi, Takahara, Harabuchi: Expression of CD70 in nasal natural killer/T cell lymphoma cell lines and patients; its role for cell proliferation through binding to soluble CD27. in British journal of haematology 2013
HSCs appear to maintain expression of CD27 after hematopoietic injury when Kit expression is downregulated.
Mature CD27low NK cells promote allograft survival under costimulatory blockade conditions by regulating alloreactive memory CD8+ T-cell responses in T-bet dependent manner.
identify an IL-17 (show IL17A Proteins)-dependent lymphoid/myeloid cross-talk involving CD27(-) gammadelta T cells and small peritoneal macrophages that promotes ovarian tumor cell growth and thus counteracts cancer immunosurveillance
memory CD8 (show CD8A Proteins) T cells, generated through priming with CD27 agonists, proliferated more extensively than did 4-1BB (show TNFRSF9 Proteins)-generated memory cells, but these cells failed to persist.
the central role played by CD27/70 during secondary CD8 (show CD8A Proteins)(+) T-cell activation to a peptide Ag, and identify sCD70 as an immunotherapeutic adjuvant for antitumor immunity.
under conditions of constitutive CD70 (show CD70 Proteins) expression reflecting chronic immune activation, the CD27/CD70 (show CD70 Proteins) system inhibits OC differentiation and favors DC differentiation
mTECs and DCs form dedicated niches in the thymic medulla, in which CD27-CD70 (show CD70 Proteins) co-stimulation rescues developing Treg cells from apoptosis, subsequent to Foxp3 (show FOXP3 Proteins) induction by TCR and CD28 (show CD28 Proteins) signals.
The CD27 and CD70 (show CD70 Proteins) costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity.
population of CD27(-) Th2 cells was significantly reduced by the anti-CD70 (show CD70 Proteins) mAb treatment
The CD4 (show CD4 Proteins)+ T-cell help signal is transmitted from APC (show APC Proteins) to CD8 (show CD8A Proteins)+ T-cells via CD27-CD70 (show CD70 Proteins) interactions.
HCV infection increased the frequency of CD4 (show CD4 Proteins)+CXCR5 (show CXCR5 Proteins)+ T cells and decreased the frequency of CD27+IgG+ B cells. CD4 (show CD4 Proteins)+CXCR5 (show CXCR5 Proteins)+ T cells activated CD27+IgG+ B cells via the secretion of IL-21 (show IL17C Proteins).
Novel mutations in TNFRSF7/CD27 cause EBV-associated lymphoproliferative disease/hemophagocytic lymphohistiocytosis, Hodgkin lymphoma, uveitis, and recurrent infections.
NFKB1 (show NFKB1 Proteins), CD27, LAG3 (show LAG3 Proteins) and IKZF3 (show IKZF3 Proteins) are new susceptibility genes for psoriasis.
results provide the first evidence for differential expression of CD27 among CLL prognostic groups, suggest a role for ZAP-70 (show ZAP70 Proteins) dependent signaling in CD27 induction and implicate CD27 in cell-cell interactions with the lymphoid tissue microenvironment
A lower primary CD24 (show CD24 Proteins)(hi) CD27(+) CD19 (show CD19 Proteins)(+) B cells may be an immunologic aspect of new-onset SLE that may be a useful tool to evaluate lupus activity and monitor the response to therapy.
Multiple layers of memory B cells to T cell- dependent antigens describe immunoglobulin IgM+ B cells representing a memory reservoir that can re-enter the germinal center, ensuring replenishment of class-switched memory CD27+ B cells.
Data indicate a unique expansion of CD27(high) plasmablasts in both the cerebrospinal fluid and periphery of transverse myelitis (TM). patients
CD27positive B cells from common variable immunodeficiency (CVID (show TNFRSF13B Proteins)) patients are more sensitive than CD27negative B cells to spontaneous apoptosis and less sensitive to rescue from apoptosis; these B cells fail to differentiate to memory or plasma cells.
lack of functional CD27 predisposes towards a combined immunodeficiency associated with potentially fatal EBV-driven hemo-phagocytosis, lymphoproliferation (show FAS Proteins), and lymphoma development.
The CCR7 (show CCR7 Proteins)+CD45RA-CD27+CD28 (show CD28 Proteins)+ central memory subset is significantly decreased in the peripheral blood CD4 (show CD4 Proteins)+ T cells from rheumatoid arthritis patients.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
tumor necrosis factor receptor superfamily, member 7
, CD27 antigen
, CD27L receptor
, CD antigen 27
, T-cell activation antigen CD27
, tumor necrosis factor receptor superfamily member 7
, T cell activation antigen S152