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CD27 Protein (His tag,Fc Tag)

CD27 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320754
  • Target See all CD27 Proteins
    CD27 (CD27 Molecule (CD27))
    Protein Type
    Recombinant
    Origin
    • 24
    • 10
    • 3
    • 3
    • 1
    Mouse
    Source
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD27 protein is labelled with His tag,Fc Tag.
    Purpose
    Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag)
    Sequence
    Pro24-Arg182
    Characteristics
    Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD27 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD27 (CD27 Molecule (CD27))
    Alternative Name
    CD27/TNFRSF7 (CD27 Products)
    Synonyms
    TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein
    Background

    Background: Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

    Synonym: CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7,S152,Tnfrsf7,Tp55

    Molecular Weight
    45.8 kDa
    NCBI Accession
    NP_001028298
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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