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Browse our anti-FDFT1 (FDFT1) Antibodies

Full name:
anti-Farnesyl-Diphosphate Farnesyltransferase 1 Antibodies (FDFT1)
On www.antibodies-online.com are 105 Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Antibodies from 15 different suppliers available. Additionally we are shipping FDFT1 Kits (26) and FDFT1 Proteins (11) and many more products for this protein. A total of 149 FDFT1 products are currently listed.
Synonyms:
DGPT, DKFZp459C1712, ERG9, fdft1, SQS, SS
list all antibodies Gene Name GeneID UniProt
FDFT1 14137 P53798
FDFT1 29580 Q02769
FDFT1 2222 P37268

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Most Popular Reactivities for anti-FDFT1 (FDFT1) Antibodies

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anti-Mouse (Murine) FDFT1 Antibodies:

anti-Rat (Rattus) FDFT1 Antibodies:

anti-Human FDFT1 Antibodies:

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Top referenced anti-FDFT1 Antibodies

  1. Human Polyclonal FDFT1 Primary Antibody for EIA, IHC (p) - ABIN357711 : Soltis, McMahon, Caplan, Dudas, Chamberlin, Vattay, Dottavio, Rucker, Engstrom, Cornell-Kennon: Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems. in Archives of biochemistry and biophysics 1995 (PubMed)
    Show all 6 references for ABIN357711

  2. Human Polyclonal FDFT1 Primary Antibody for IHC (p), WB - ABIN389052 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 4 references for ABIN389052

  3. Human Polyclonal FDFT1 Primary Antibody for WB - ABIN658482 : Chalasani, Guo, Loomba, Goodarzi, Haritunians, Kwon, Cui, Taylor, Wilson, Cummings, Chen, Rotter,: Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. in Gastroenterology 2010 (PubMed)
    Show all 2 references for ABIN658482

  4. Human Polyclonal FDFT1 Primary Antibody for ICC, IF - ABIN4311300 : Wu, Hsu, Chen, Yu, Chang, Tai, Liu, Su, Chang, Yu: Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. in Molecular & cellular proteomics : MCP 2010 (PubMed)

  5. Cow (Bovine) Polyclonal FDFT1 Primary Antibody for WB - ABIN4271866 : Healey, Collier, Griffin, Schuberth, Sandra, Smith, Mahan, Dieuzy-Labaye, Sheldon: Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)

More Antibodies against FDFT1 Interaction Partners

Mouse (Murine) Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) interaction partners

  1. This study demonistrated that fdft1 is regulate the neuronal cholesterol synthesis during neurite outgrowth.

  2. Result provides the first in vivo evidence that SS plays a regulatory role in cholesterol metabolism through modulation of HMG-CoA reductase (show HMGCR Antibodies) activity and cholesterol biosynthesis.

  3. VEGF (show VEGFA Antibodies) expression, APOPTOSIS, AND ANGIOGENESIS in squalene synthase -ablated neural stem cells wERE strongly upregulated

Human Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) interaction partners

  1. The results indicate that the ennea-peptide CLSPHSMFC, tetra-peptides SMFC, CKTE, and WHQW can effectively inhibit Squalene Synthase activities (IC50 values equal to 64, 76, 87, and 90 muM, respectively)

  2. The minor allele in FDFT1 was associated with advanced fibrosis in the non-steatotic but not in the steatotic subgroup in patients with chronic hepatitis C.

  3. Up-regulation of SQS promotes metastasis of lung cancer by enhancing tumor necrosis factor-alpha receptor (show TNFRSF1A Antibodies) 1 and nuclear factor-kappaB activation and matrix metallopeptidase (show ECEL1 Antibodies) 1 expression.

  4. Several critical residues that are involved in binding of NADPH (show NQO1 Antibodies) have been identified in the active site of squalene synthase.

  5. HCV infection increases FDFT1 protein level but not FDFT1 mRNA level.

  6. ABHD5 (show ABHD5 Antibodies), PGRMC1 (show PGRMC1 Antibodies) and SQS are novel markers for sebaceous carcinoma and can reliably distinguish sebaceous neoplasms from non-sebaceous tumors, specifically BCC with clear cell features.

  7. FDFT1 and its encoded enzyme, squalene synthase, may play an important role in prostate cancer development and its aggressive phenotypes.

  8. CTSB (show CTSB Antibodies) and FDFT1 are excluded as candidates for keratolytic winter erythema

  9. NASH (show SAMSN1 Antibodies) is intimately related to fibrosis progression, the FDFT1 SNP is a good candidate for a link with inflammation and fibrosis.

  10. In multivariate models adjusted for age, body mass index, diabetes, waist/hip ratios, and levels of glycated hemoglobin (show HBB Antibodies), the NAFLD (show TSC2 Antibodies) activity score was associated with the SNP rs2645424 on chromosome 8 in farnesyl diphosphate farnesyl transferase 1 (FDFT1)

FDFT1 Antigen Profile

Antigen Summary

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Alternative names and synonyms associated with FDFT1

  • farnesyl-diphosphate farnesyltransferase 1 (FDFT1) antibody
  • farnesyl-diphosphate farnesyltransferase 1 (fdft1) antibody
  • farnesyl-diphosphate farnesyltransferase 1 (LOC100217567) antibody
  • farnesyl diphosphate farnesyl transferase 1 (Fdft1) antibody
  • farnesyl-diphosphate farnesyltransferase 1 (Fdft1) antibody
  • si:ch73-107c13.2 (si:ch73-107c13.2) antibody
  • DGPT antibody
  • DKFZp459C1712 antibody
  • ERG9 antibody
  • fdft1 antibody
  • SQS antibody
  • SS antibody

Protein level used designations for FDFT1

farnesyl-diphosphate farnesyltransferase 1 , squalene synthase , SS , SQS , Squalene synthetase , FPP:FPP farnesyltransferase , squalene synthase-like , farnesyl-diphosphate farnesyltransferase , squalene synthetase , farnesyl diphosphate farnesyltransferase , presqualene-di-diphosphate synthase

GENE ID SPECIES
696396 Macaca mulatta
740684 Pan troglodytes
100029000 Monodelphis domestica
100173463 Pongo abelii
100216201 Xenopus (Silurana) tropicalis
100479603 Ailuropoda melanoleuca
100560926 Anolis carolinensis
100603333 Nomascus leucogenys
100217567 Taeniopygia guttata
14137 Mus musculus
29580 Rattus norvegicus
422038 Gallus gallus
2222 Homo sapiens
477362 Canis lupus familiaris
100312971 Sus scrofa
281767 Bos taurus
100345480 Oryctolagus cuniculus
100714445 Cavia porcellus
101119109 Ovis aries
571911 Danio rerio
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