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FDFT1 Products

(Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

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This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008].

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Featured FDFT1 Categories

FDFT1 Antibodies

High quality antibodies with extensive validation data.

FDFT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FDFT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FDFT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7433993
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IF, IHC (p)
Validations
  • (12)
Cat. No. ABIN1498243
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (4)
Cat. No. ABIN389052
Quantity 400 μL
Datasheet Datasheet

Recommended FDFT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593753
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN776835
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN774880
Quantity 96 tests
Datasheet Datasheet

Recommended FDFT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353932
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394720
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403129
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FDFT1 products

Healey, Collier, Griffin, Schuberth, Sandra, Smith, Mahan, Dieuzy-Labaye, Sheldon: "Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 2, pp. 823-31, (2016) (PubMed).

Zhang, Dai, Wang: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).

Hammer, Bien, Salazar, Steil, Scharf, Hildebrandt, Schroeder, Kroemer, Völker, Ritter: "Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches." in: Proteomics, Vol. 10, Issue 1, pp. 99-114, (2010) (PubMed).

Wu, Hsu, Chen, Yu, Chang, Tai, Liu, Su, Chang, Yu: "Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 6, pp. 1100-17, (2010) (PubMed).

Størvold, Fleten, Olsen, Follestad, Krokan, Schønberg: "Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells." in: Lipids, Vol. 44, Issue 8, pp. 673-83, (2009) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Synonyms and alternative names related to FDFT1

farnesyl-diphosphate farnesyltransferase 1 (FDFT1), farnesyl-diphosphate farnesyltransferase 1 (fdft1), squalene synthase (LOC100560926), farnesyl diphosphate farnesyl transferase 1 (Fdft1), farnesyl-diphosphate farnesyltransferase 1 (Fdft1), DGPT, DKFZp459C1712, ERG9, FDFT1, fdft1, SQS, SS

Protein level used designations for FDFT1

  • farnesyl-diphosphate farnesyltransferase 1
  • squalene synthase
  • SS
  • SQS
  • Squalene synthetase
  • FPP:FPP farnesyltransferase
  • squalene synthase-like
  • farnesyl-diphosphate farnesyltransferase
  • squalene synthetase
  • farnesyl diphosphate farnesyltransferase
  • presqualene-di-diphosphate synthase
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