Browse our anti-ZEB1 (ZEB1) Antibodies

Full name:
anti-Zinc Finger E-Box Binding Homeobox 1 Antibodies (ZEB1)
On www.antibodies-online.com are 188 Zinc Finger E-Box Binding Homeobox 1 (ZEB1) Antibodies from 23 different suppliers available. Additionally we are shipping ZEB1 Kits (9) and and many more products for this protein. A total of 205 ZEB1 products are currently listed.
Synonyms:
3110032K11Rik, AREB6, BZP, deltaef1, fecd6, kheper, MEB1, MGC97552, nil-2-a, nil-2a, Nil2, NIL2A, PPCD3, TCF-8, Tcf8, Tcf18, Tw, ZEB, zeb1, ZFH/[d]EF1, Zfhep, zfhx1, Zfhx1a, Zfx1a, Zfx1ha, [delta]EF1
list all antibodies Gene Name GeneID UniProt
ZEB1 6935 P37275
ZEB1 21417 Q64318
ZEB1 25705  

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anti-Human ZEB1 Antibodies:

anti-Mouse (Murine) ZEB1 Antibodies:

anti-Rat (Rattus) ZEB1 Antibodies:

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Top referenced anti-ZEB1 Antibodies

  1. Human Polyclonal ZEB1 Primary Antibody for GS, ICC - ABIN438412 : Gregory, Bracken, Smith, Bert, Wright, Roslan, Morris, Wyatt, Farshid, Lim, Lindeman, Shannon, Drew, Khew-Goodall, Goodall: An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. in Molecular biology of the cell 2011 (PubMed)
    Show all 29 references for 438412

  2. Human Polyclonal ZEB1 Primary Antibody for ICC, IF - ABIN4366799 : Hanna, Wimberly, Kumar, Slack, Agarwal, Rimm: Quantitative analysis of microRNAs in tissue microarrays by in situ hybridization. in BioTechniques 2012 (PubMed)
    Show all 18 references for 4366799

  3. Human Polyclonal ZEB1 Primary Antibody for ELISA, WB - ABIN449907 : Kurasawa, Kozaki, Pimkhaokham, Muramatsu, Ono, Ishihara, Uzawa, Imoto, Amagasa, Inazawa: Stabilization of phenotypic plasticity through mesenchymal-specific DNA hypermethylation in cancer cells. in Oncogene 2012 (PubMed)
    Show all 2 references for 449907

  4. Human Monoclonal ZEB1 Primary Antibody for ICC, FACS - ABIN1724885 : Liu, Yan, Liu, Zhou, Liu, Pang, Cao, Liu, Wang, Liu, Zhang: Lentivirus-delivered ZEB-1 small interfering RNA inhibits lung adenocarcinoma cell growth in vitro and in vivo. in Journal of cancer research and clinical oncology 2012 (PubMed)
    Show all 2 references for 1724885

  5. Human Polyclonal ZEB1 Primary Antibody for FACS, IF (p) - ABIN755113 : Sasaki, Kuniyasu, Luo, Kato, Shinya, Fujii, Ohmori, Yamashita: Significance of epithelial growth factor in the epithelial-mesenchymal transition of human gallbladder cancer cells. in Cancer science 2012 (PubMed)
    Show all 2 references for 755113

  6. Cow (Bovine) Polyclonal ZEB1 Primary Antibody for IHC, WB - ABIN2777193 : Kothandaraman, Bajic, Brendan, Huak, Keow, Razvi, Salto-Tellez, Choolani: E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer. in BMC cancer 2010 (PubMed)
    Show all 2 references for 2777193

  7. Human Monoclonal ZEB1 Primary Antibody for FACS, WB - ABIN659081 : Drake, Barnes, Madsen, Domann, Stipp, Henry: ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 references for 659081

  8. Cow (Bovine) Polyclonal ZEB1 Primary Antibody for IF, WB - ABIN2779631 : Gregory, Bert, Paterson, Barry, Tsykin, Farshid, Vadas, Khew-Goodall, Goodall: The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. in Nature cell biology 2008 (PubMed)
    Show all 2 references for 2779631

  9. Human Polyclonal ZEB1 Primary Antibody for WB - ABIN2792549 : Williams, Moolten, Burlein, Romano, Bhaerman, Godillot, Mellon, Rauscher, Kant: Identification of a zinc finger protein that inhibits IL-2 gene expression. in Science (New York, N.Y.) 1992 (PubMed)

More Antibodies against ZEB1 Interaction Partners

Zebrafish Zinc Finger E-Box Binding Homeobox 1 (ZEB1) interaction partners

  1. Zeb1 proteins employ several evolutionary conserved mechanisms to regulate cell-cell adhesion during development and cancer

Human Zinc Finger E-Box Binding Homeobox 1 (ZEB1) interaction partners

  1. The Thymidylate synthase (show TYMS Antibodies) (TS)-ZEB1 association was confirmed in clinical specimens from lung tumours and in a genetic mouse model of pancreatic cancer with ZEB1 deletion. Interestingly, TS itself appeared to have a regulatory role in epithelial-to-mesenchymal in cancer cells, as TS knockdown could directly reduce the EMT (show ITK Antibodies) phenotype, the migratory ability of cells, the expression of stem-like markers, and chemoresistance.

  2. the miR (show MLXIP Antibodies)-200b-ZEB1 circuit is closely involved with the induction and maintenance of a diverse group of cancer stem cells

  3. ZEB1 upregulation by SPRY2 (show SPRY2 Antibodies) results from the combined induction of ETS1 (show ETS1 Antibodies) transcription factor and the repression of microRNAs (miR (show MLXIP Antibodies)-200 family, miR (show MLXIP Antibodies)-150) that target ZEB1 RNA. Moreover, SPRY2 (show SPRY2 Antibodies) increased AKT (show AKT1 Antibodies) activation by epidermal growth factor (show EGF Antibodies), whereas AKT (show AKT1 Antibodies) and also Src (show SRC Antibodies) inhibition reduced the induction of ZEB1.

  4. Authors observed association between dephosphorylated Rb with ZEB1, a zinc-finger E-box-binding transcription factor that regulates expression of E- and N-cadherins. Finally Rb dephosphorylation led to inhibition of ZEB1 transcriptional activity, this data supports the notion that Rb dephosphorylation modulates the EMT (show ITK Antibodies).

  5. Network analysis on shortest paths connecting gene targets suggested ZEB1 and TP53 (show TP53 Antibodies) as key miRNA targets during the follicular differentiation pathway. These data confirm and extend our knowledge on the miRNAs-related regulatory pathways involved in the late B cell maturation (show TNFRSF17 Antibodies).

  6. ZEB1-induced epithelial-to-mesenchymal transition and associated molecular changes in ESRP1 (show ESRP1 Antibodies) and CD44 (show CD44 Antibodies) contribute to early pathogenesis and metastatic potential in established lung cancer

  7. We identified HAS2 (show HAS2 Antibodies), tumor cell-derived hyaluronic acid (HA) and ZEB1 to form a positive feedback loop as ZEB1, elevated by HA, directly activates HAS2 (show HAS2 Antibodies) expression in breast cancer

  8. CSN5 (show COPS5 Antibodies) led to the metastasis and EMT (show ITK Antibodies) activation of RCC (show XRCC1 Antibodies) cells through increasing ZEB1 expression. Mechanistically, CSN5 (show COPS5 Antibodies) directly bound ZEB1 and decreased its ubiquitination to enhance the protein stability of ZEB1 in RCC (show XRCC1 Antibodies) cells.

  9. Overall, these results demonstrate that ZEB1 is a major driver of melanoma cell plasticity, driving drug adaptation and phenotypic resistance to MAPK (show MAPK1 Antibodies) inhibitors.

  10. Ets1 (show ETS1 Antibodies) induces ZEB expression and activates the ZEB1 promoter.

Mouse (Murine) Zinc Finger E-Box Binding Homeobox 1 (ZEB1) interaction partners

  1. activation of hepatic H19RNA promoted cholestatic liver fibrosis through the ZEB1/EpCAM (show EPCAM Antibodies) signaling pathway

  2. Furthermore, activation of the EMT (show ITK Antibodies) program on its own, as orchestrated by Zeb1, is sufficient to incite metastatic outgrowth by causing carcinoma cells to enter stably into a metastasis-initiating cell state.

  3. Epithelial mesenchymal transformation-transcription factor Zeb1 is a key driver of pancreatic tumour progression from early tumorigenesis to late-stage metastasis, underscoring the important role of EMT (show ITK Antibodies) activation in these processes.

  4. Data suggest that, in a cell transdifferentiation system to convert mouse embryonic fibroblasts into functional neurons (transplanted into hippocampus), expression of Zeb1 is up-regulated during the early stages of transdifferentiation; knockdown of Zeb1 expression dramatically attenuates cell transdifferentiation efficiency; Zeb1 overexpression up-regulates expression of neuron-specific genes.

  5. This work has established a new role for ZEB1 as an inhibitor of senescence in cancer cells, thus expanding the set of cancer cell hallmarks regulated by ZEB1.

  6. The results suggest that an antagonistic cascade exists between the TGF-beta1/Smad/deltaEF1 pathways and Npr1 expression and receptor signaling that is relevant to renal and vascular remodeling, and may be critical in the regulation of blood pressure and cardiovascular homeostasis.

  7. Zeb1 promotes proliferation and apoptosis and inhibits the migration of metanephric mesenchyme cells, in association with Six2 (show SIX2 Antibodies).

  8. Porphyromonas gingivalis regulates ZEB1 expression in gingival epithelial cells.

  9. decrease of ZEB1 expression resulted in inhibitory effects on the B16F10 CD133+CD44 (show CD44 Antibodies)+ cancer-stem-cell-like properties, and reduced the tumorigenesis and metastatic potential in the melanoma model

  10. CRP (show CRP Antibodies) suppresses expression of N-cadherin (show CDH2 Antibodies) (p < 0.01), a mesenchymal marker of EMT (show ITK Antibodies), and ZEB-1, an EMT (show ITK Antibodies)-related transcription factor (p < 0.01). These findings suggest that CRP (show CRP Antibodies) inhibits EMT (show ITK Antibodies) in a MCA (show RSPH1 Antibodies)-38 tumor-bearing mouse model.

ZEB1 Antigen Profile

Antigen Summary

This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with ZEB1

  • zinc finger E-box binding homeobox 1b (zeb1b) antibody
  • zinc finger E-box binding homeobox 1 (zeb1) antibody
  • zinc finger E-box binding homeobox 1 (ZEB1) antibody
  • zinc finger E-box binding homeobox 1 (LOC100226179) antibody
  • zinc finger E-box binding homeobox 1 (Zeb1) antibody
  • 3110032K11Rik antibody
  • AREB6 antibody
  • BZP antibody
  • deltaef1 antibody
  • fecd6 antibody
  • kheper antibody
  • MEB1 antibody
  • MGC97552 antibody
  • nil-2-a antibody
  • nil-2a antibody
  • Nil2 antibody
  • NIL2A antibody
  • PPCD3 antibody
  • TCF-8 antibody
  • Tcf8 antibody
  • Tcf18 antibody
  • Tw antibody
  • ZEB antibody
  • zeb1 antibody
  • ZFH/[d]EF1 antibody
  • Zfhep antibody
  • zfhx1 antibody
  • Zfhx1a antibody
  • Zfx1a antibody
  • Zfx1ha antibody
  • [delta]EF1 antibody

Protein level used designations for ZEB1

zfhx1a , zinc finger E-box binding homeobox 1 , zinc finger E-box-binding homeobox 1 , zinc finger homeobox 1 , transcription factor 8 (represses interleukin 2 expression) , zinc finger E-box-binding homeobox 1-like , delta-crystallin enhancer binding factor 1 , negative regulator of IL2 , posterior polymorphous corneal dystrophy 3 , zinc finger homeodomain enhancer-binding protein , transcription factor 8 , twirler , zinc finger homeobox protein 1a , TCF-8 , zfhep , delta EF1 , delta-crystallin enhancer-binding factor , deltaEF1

GENE ID SPECIES
114425 Danio rerio
548525 Xenopus (Silurana) tropicalis
701157 Macaca mulatta
100171534 Pongo abelii
100226179 Taeniopygia guttata
100386906 Callithrix jacchus
100473701 Ailuropoda melanoleuca
6935 Homo sapiens
21417 Mus musculus
25705 Rattus norvegicus
444391 Xenopus laevis
396029 Gallus gallus
477966 Canis lupus familiaris
535183 Bos taurus
100520325 Sus scrofa
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