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ZEB1 Products

(Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

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This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010].

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Featured ZEB1 Categories

ZEB1 Antibodies

High quality antibodies with extensive validation data.

ZEB1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended ZEB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN1724885
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
  • (5)
Cat. No. ABIN520780
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application WB, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN2779631
Quantity 100 μL
Datasheet Datasheet

Recommended ZEB1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971219
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5593446
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1167841
Quantity 96 tests
Datasheet Datasheet

Recommended ZEB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125772
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325707
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3096429
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ZEB1 products

Fang, Lin, Liang, Liang: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).

Ordonez, Hay, McEwen, Polanska, Hughes, Delpuech, Cadogan, Powell, Dry, Tornillo, Silcock, Leo, OConnor, Clarke, Smalley: "Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours." in: Oncotarget, Vol. 10, Issue 27, pp. 2586-2606, (2019) (PubMed).

Katsuno, Meyer, Zhang, Shokat, Akhurst, Miyazono, Derynck: "Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition." in: Science signaling, Vol. 12, Issue 570, (2019) (PubMed).

Fujiwara, Saiki, Ishizawa, Fukushige, Yamanaka, Sato, Ishida, Motoi, Unno, Horii: "Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas." in: Cancer medicine, Vol. 8, Issue 4, pp. 1671-1678, (2019) (PubMed).

Rios, Capaldo, Vaillant, Pal, van Ineveld, Dawson, Chen, Nolan, Fu, Jackling, Devi, Clouston, Whitehead, Smyth, Mueller, Lindeman, Visvader: "Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging." in: Cancer cell, Vol. 35, Issue 4, pp. 618-632.e6, (2019) (PubMed).

Maturi, Morén, Enroth, Heldin, Moustakas: "Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells." in: Molecular oncology, Vol. 12, Issue 7, pp. 1153-1174, (2019) (PubMed).

Vanneste, Huang, Li, Moose, Zhao, Stamnes, Schultz, Wu, Henry: "High content screening identifies monensin as an EMT-selective cytotoxic compound." in: Scientific reports, Vol. 9, Issue 1, pp. 1200, (2019) (PubMed).

Sippel, Johnson, Li, Hanson, Nguyen, Bullock, Poczobutt, Kwak, Kleczko, Weiser-Evans, Nemenoff: "Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGFβ1." in: Molecular cancer research : MCR, Vol. 17, Issue 8, pp. 1748-1758, (2019) (PubMed).

You, Li, Cao, Gu, Deng, Tan, Hu: "Snail1-dependent cancer-associated fibroblasts induce epithelial-mesenchymal transition in lung cancer cells via exosomes." in: QJM : monthly journal of the Association of Physicians, Vol. 112, Issue 8, pp. 581-590, (2019) (PubMed).

Yoon, Till, Cho, Chang, Lin, Huang, Ryeom, Yoon: "KRAS Activation in Gastric Adenocarcinoma Stimulates Epithelial-to-Mesenchymal Transition to Cancer Stem-Like Cells and Promotes Metastasis." in: Molecular cancer research : MCR, Vol. 17, Issue 9, pp. 1945-1957, (2019) (PubMed).

Synonyms and alternative names related to ZEB1

zinc finger E-box binding homeobox 1b (zeb1b), zinc finger E-box binding homeobox 1 (zeb1), zinc finger E-box binding homeobox 1 (ZEB1), zinc finger E-box binding homeobox 1 (Zeb1), zinc finger E-box binding homeobox 1 S homeolog (zeb1.S), 3110032K11Rik, areb6, AREB6, bzp, BZP, DELTAEF1, deltaEF1, deltaef1, FECD6, fecd6, kheper, MEB1, MGC97552, nil-2-a, nil-2a, Nil2, nil2a, NIL2A, PPCD3, TCF-8, tcf8, TCF8, Tcf8, Tcf18, Tw, zeb, ZEB, zeb1, ZFH/[d]EF1, zfhep, ZFHEP, Zfhep, zfhx1, zfhx1a, ZFHX1A, Zfhx1a, Zfx1a, Zfx1ha, [delta]EF1

Protein level used designations for ZEB1

  • zfhx1a
  • zinc finger E-box binding homeobox 1
  • zinc finger E-box-binding homeobox 1
  • zinc finger homeobox 1
  • transcription factor 8 (represses interleukin 2 expression)
  • zinc finger E-box-binding homeobox 1-like
  • delta-crystallin enhancer binding factor 1
  • negative regulator of IL2
  • posterior polymorphous corneal dystrophy 3
  • zinc finger homeodomain enhancer-binding protein
  • transcription factor 8
  • twirler
  • zinc finger homeobox protein 1a
  • TCF-8
  • zfhep
  • delta EF1
  • delta-crystallin enhancer-binding factor
  • deltaEF1
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