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Browse our DROSHA Proteins (DROSHA)

Full name:
Drosha, Ribonuclease Type III Proteins (DROSHA)
On www.antibodies-online.com are 6 Drosha, Ribonuclease Type III (DROSHA) Proteins from 4 different suppliers available. Additionally we are shipping DROSHA Antibodies (63) and DROSHA Kits (11) and many more products for this protein. A total of 87 DROSHA products are currently listed.
Synonyms:
1110013A17Rik, AI874853, Etohi2, HSA242976, im:7150667, RANSE3L, RGD1307626, Rn3, RNASE3L, Rnasen, zgc:158612
list all proteins Gene Name GeneID UniProt
DROSHA 29102 Q9NRR4
DROSHA 14000 Q5HZJ0
Rat DROSHA DROSHA 310159  

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DROSHA Proteins (DROSHA) by Origin

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More Proteins for DROSHA Interaction Partners

Human Drosha, Ribonuclease Type III (DROSHA) interaction partners

  1. An essential role of DROSHA in the canonical miRNA pathway

  2. DICER1 (show DICER1 Proteins) and DROSHA copy number variation may be an important mechanism of upregulation/downregulation of miRNAs in lung cancer

  3. Gradual loss of cytoplasmic Drosha was accompanied by tumor progression in both gastric cancer tissues and cell lines, and was inversely associated with tumor volume (P = 0.002), tumor grade (P < 0.001), tumor stage (P = 0.018), and distant metastasis

  4. we found that both the structural features of shmiR hairpins and the nucleotide sequence at Drosha and Dicer (show DICER1 Proteins) processing sites contribute to cleavage site selection and cleavage precision.

  5. DGCR8 (show DGCR8 Proteins) and Drosha assemble into a heterotrimeric complex on RNA, comprising two DGCR8 (show DGCR8 Proteins) molecules and one Drosha molecule.

  6. Study reports the X-ray structure of DROSHA in complex with the C-terminal helix of DGCR8 (show DGCR8 Proteins); DROSHA contains two DGCR8 (show DGCR8 Proteins)-binding sites, one on each RNase III domain (RIIID), which mediate the assembly of Microprocessor; overall structure of DROSHA is surprisingly similar to that of Dicer (show DICER1 Proteins) despite no sequence homology apart from the C-terminal part.

  7. Results indicate the role of Drosha, Dicer (show DICER1 Proteins) and Ago2 (show EIF2C2 Proteins) proteins in the development of non-small cell lung carcinomas (NSCLC) and suggest that Dicer (show DICER1 Proteins) may be implicated in the progression of these tumors to advanced stages.

  8. We aimed to evaluate the expression of the major components of microRNA biogenesis machinery including Drosha, Dicer (show DICER1 Proteins) and DiGeorge syndrome critical region gene 8 (DGCR8 (show DGCR8 Proteins)) in multiple sclerosis patients

  9. Variations in DROSHA rs10719 of Korean patients are significantly associated with their risk of colorectal cancer.

  10. Drosha expression was reduced gradually with the degrading histological differentiation of gastric adenocarcinoma, and the knock-down of Drosha expression could promote gastric adenocarcinoma cell invasion.

Mouse (Murine) Drosha, Ribonuclease Type III (DROSHA) interaction partners

  1. These data indicate that oocyte DICER (show DICER1 Proteins) expression in the fetal ovary is required, and oocyte DROSHA is dispensable, for postnatal follicular development and female fertility in adulthood.

  2. Drosha repressed the expression of two mRNAs encoding inhibitors of myelopoiesis in early hematopoietic progenitors.

  3. Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.

  4. Data indicate that Arf-deficient cells transformed by oncogenic Ras were dependent on increased Drosha expression as Drosha knockdown was sufficient to inhibit Ras-dependent cellular transformation.

  5. Drosha is required for VSMC survival by targeting multiple signaling pathways.

  6. the podocyte-specific deletion of Drosha results in a similar phenotype to Dicer (show DICER1 Proteins) mutants, confirming that the Dicer (show DICER1 Proteins) mutant phenotype is due to the loss of miRNAs

  7. DROSHA is essential mainly for the canonical miRNA production, and DROSHA-mediated miRNA production is essential for normal spermatogenesis and male fertility.

  8. Drosha is required for maintenance of neural stem cell self-renewal.

  9. epidermal Dicer (show DICER1 Proteins) and Drosha have multiple functions in postnatal skin

  10. The expression profiles of Hoxd4 (show HOXD4 Proteins) and miR (show MLXIP Proteins)-10b transcripts during neural differentiation of mouse embryonal carcinoma (EC) P19 (show CDKN2D Proteins) cells are co-ordinately regulated and generated by Drosha cleavage.

DROSHA Protein Profile

Protein Summary

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002

Alternative names and synonyms associated with DROSHA

  • ribonuclease type III, nuclear (rnasen)
  • Ribonuclease 3 (Thicy_0885)
  • Ribonuclease 3 (Sinme_0866)
  • ribonuclease 3 (Isova_2087)
  • Ribonuclease 3 (Sphch_0770)
  • drosha, ribonuclease type III (DROSHA)
  • drosha, ribonuclease type III (Drosha)
  • ribonuclease III, nuclear (LOC100349331)
  • 1110013A17Rik protein
  • AI874853 protein
  • Etohi2 protein
  • HSA242976 protein
  • im:7150667 protein
  • RANSE3L protein
  • RGD1307626 protein
  • Rn3 protein
  • RNASE3L protein
  • Rnasen protein
  • zgc:158612 protein

Protein level used designations for DROSHA

drosha , ribonuclease 3 , Ribonuclease 3 , RNase III , drosha, double-stranded RNA-specific endoribonuclease , nuclear RNase III Drosha , p241 , protein Drosha , putative protein p241 which interacts with transcription factor Sp1 , putative ribonuclease III , ribonuclease III, nuclear , ribonuclease type III, nuclear , ethanol induced 2

GENE ID SPECIES
567505 Danio rerio
10719711 Thioalkalimicrobium cyclicum ALM1
10725435 Sinorhizobium meliloti AK83
10733713 Isoptericola variabilis 225
10741092 Sphingobium chlorophenolicum L-1
29102 Homo sapiens
479375 Canis lupus familiaris
14000 Mus musculus
310159 Rattus norvegicus
420911 Gallus gallus
540168 Bos taurus
100349331 Oryctolagus cuniculus
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