Browse our DROSHA Proteins (DROSHA)

Full name:
Drosha, Ribonuclease Type III Proteins (DROSHA)
On are 6 Drosha, Ribonuclease Type III (DROSHA) Proteins from 4 different suppliers available. Additionally we are shipping DROSHA Antibodies (69) and DROSHA Kits (14) and many more products for this protein. A total of 96 DROSHA products are currently listed.
1110013A17Rik, AI874853, Etohi2, HSA242976, im:7150667, RANSE3L, RGD1307626, Rn3, RNASE3L, Rnasen, zgc:158612
list all proteins Gene Name GeneID UniProt
Rat DROSHA DROSHA 310159  

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DROSHA Proteins (DROSHA) by Origin

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More Proteins for DROSHA Interaction Partners

Human Drosha, Ribonuclease Type III (DROSHA) interaction partners

  1. HPV E6/E7 increased expression of DROSHA and DICER (show DICER1 Proteins) mRNA and protein in cervical carcinoma cells.

  2. Knockdown of Drosha, the apoptosis rate of MGC-803 cells was increased, the protein expressions of caspase-3 (show CASP3 Proteins) , caspase-9 (show CASP9 Proteins) and Bax (show BAX Proteins) were significantly upregulated and Bcl-2 (show BCL2 Proteins) was downregulated.

  3. The rs417309 and rs1640299 polymorphisms of the DGCR8 (show DGCR8 Proteins) gene as well as rs6877842 of the DROSHA gene might be associated with a risk of laryngeal cancer occurrence in the Polish population.

  4. miR (show MLXIP Proteins)-27b mimics, DROSHA siRNA, and miR (show MLXIP Proteins)-27b inhibitors to verify the negative regulatory relationship between MiR (show MLXIP Proteins)-27b and DROSHA. The presence of rs10719 disrupted the interaction between miR (show MLXIP Proteins)-27b and DROSHA, which might be the underlying mechanism of the observation that rs10719 is significantly associated with risk of primary hypertension.

  5. For overall breast cancer risk, three single-nucleotide polymorphisms (SNPs) in miRNA biogenesis genes DROSHA rs78393591 (OR = 0.69, 95 % CI: 0.55-0.88, P = 0.003), ESR1 (show ESR1 Proteins) rs523736 (OR = 0.88, 95 % CI: 0.82-0.95, P = 3.99 x 10(-4)), and ZCCHC11 (show ZCCHC11 Proteins) rs114101502 (OR = 1.33, 95 % CI: 1.11-1.59, P = 0.002), and one SNP in primary miRNA sequence (rs116159732 in miR (show MLXIP Proteins)-6826, OR = 0.74, 95 % CI: 0.63-0.89, P = 0.001) were found to have s

  6. Drosha and DGRC8 were significantly downregulated in healthy-appearing perilesional skin from hidradenitis suppurativa patients compared to healthy controls.

  7. Authors found that DENV4 infection exhibited the highest viral load 3 days post-infection. Dicer (show DICER1 Proteins), Drosha, and DGCR8 (show DGCR8 Proteins) showed reduced expression following DENV4 infection as compared with negative controls.

  8. Mutations of DROSHA gene underlie Wilms tumor recurrences.

  9. DICER (show DICER1 Proteins), DROSHA and DNA damage response RNAs act in the response to DNA damage after primary recognition of DNA lesions and, together with gammaH2AX (show H2AFX Proteins), are essential for enabling the secondary recruitment of DDR (show DDR1 Proteins) factors and fuel the amplification of DDR (show DDR1 Proteins) signaling.

  10. An essential role of DROSHA in the canonical miRNA pathway

Mouse (Murine) Drosha, Ribonuclease Type III (DROSHA) interaction partners

  1. Knockdown of NFIB (show NFIB Proteins) in Drosha-deficient hippocampal neural stem cells restores neurogenesis, suggesting that the Drosha/NFIB (show NFIB Proteins) mechanism robustly prevents oligodendrocyte fate acquisition in vivo.

  2. FMRP (show FMR1 Proteins) is involved in pri-miRNA processing via enhancing DROSHA expression that may play an important role in fragile X (show FMR1 Proteins) syndrome.

  3. our findings suggest that DROSHA is involved in stromal decidualization and may play an important role in embryo implantation in mice.

  4. These data indicate that oocyte DICER (show DICER1 Proteins) expression in the fetal ovary is required, and oocyte DROSHA is dispensable, for postnatal follicular development and female fertility in adulthood.

  5. Drosha repressed the expression of two mRNAs encoding inhibitors of myelopoiesis in early hematopoietic progenitors.

  6. Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.

  7. Data indicate that Arf-deficient cells transformed by oncogenic Ras were dependent on increased Drosha expression as Drosha knockdown was sufficient to inhibit Ras-dependent cellular transformation.

  8. Drosha is required for VSMC survival by targeting multiple signaling pathways.

  9. the podocyte-specific deletion of Drosha results in a similar phenotype to Dicer (show DICER1 Proteins) mutants, confirming that the Dicer (show DICER1 Proteins) mutant phenotype is due to the loss of miRNAs

  10. DROSHA is essential mainly for the canonical miRNA production, and DROSHA-mediated miRNA production is essential for normal spermatogenesis and male fertility.

DROSHA Protein Profile

Protein Summary

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002

Alternative names and synonyms associated with DROSHA

  • ribonuclease type III, nuclear (rnasen)
  • Ribonuclease 3 (Thicy_0885)
  • Ribonuclease 3 (Sinme_0866)
  • ribonuclease 3 (Isova_2087)
  • Ribonuclease 3 (Sphch_0770)
  • drosha, ribonuclease type III (DROSHA)
  • drosha, ribonuclease type III (Drosha)
  • ribonuclease III, nuclear (LOC100349331)
  • 1110013A17Rik protein
  • AI874853 protein
  • Etohi2 protein
  • HSA242976 protein
  • im:7150667 protein
  • RANSE3L protein
  • RGD1307626 protein
  • Rn3 protein
  • RNASE3L protein
  • Rnasen protein
  • zgc:158612 protein

Protein level used designations for DROSHA

drosha , ribonuclease 3 , Ribonuclease 3 , RNase III , drosha, double-stranded RNA-specific endoribonuclease , nuclear RNase III Drosha , p241 , protein Drosha , putative protein p241 which interacts with transcription factor Sp1 , putative ribonuclease III , ribonuclease III, nuclear , ribonuclease type III, nuclear , ethanol induced 2

567505 Danio rerio
10719711 Thioalkalimicrobium cyclicum ALM1
10725435 Sinorhizobium meliloti AK83
10733713 Isoptericola variabilis 225
10741092 Sphingobium chlorophenolicum L-1
29102 Homo sapiens
479375 Canis lupus familiaris
14000 Mus musculus
310159 Rattus norvegicus
420911 Gallus gallus
540168 Bos taurus
100349331 Oryctolagus cuniculus
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