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DROSHA Products

(Drosha, Ribonuclease Type III (DROSHA))
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM, Mar 2008].

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Featured DROSHA Categories

DROSHA Antibodies

High quality antibodies with extensive validation data.

DROSHA ELISA Kits

Reliable ELISA kits for a wide range of species.

DROSHA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DROSHA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7188005
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN334479
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7264363
Quantity 200 μL
Datasheet Datasheet

Recommended DROSHA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966423
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955459
Quantity 96 tests
Datasheet Datasheet

Recommended DROSHA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318168
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095060
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3135197
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DROSHA products

Veronese, Pepe, Chiacchia, Pagotto, Lanuti, Veschi, Di Marco, DArgenio, Innocenti, Vannata, Autore, Marchisio, Wernicke, Verginelli, Leone, Rassenti, Kipps, Mariani-Costantini, Laurenti, Croce, Visone: "Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia." in: Leukemia, Vol. 29, Issue 1, pp. 86-95, (2015) (PubMed).

Macias, Cordiner, Gautier, Plass, Cáceres: "DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs." in: Molecular cell, Vol. 60, Issue 6, pp. 873-85, (2015) (PubMed).

Rupaimoole, Wu, Pradeep, Ivan, Pecot, Gharpure, Nagaraja, Armaiz-Pena, McGuire, Zand, Dalton, Filant, Miller, Lu, Sadaoui, Mangala, Taylor, van den Beucken, Koch, Rodriguez-Aguayo, Huang, Bar-Eli et al.: "Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. ..." in: Nature communications, Vol. 5, pp. 5202, (2014) (PubMed).

Yamakawa, Okuyama, Ogata, Kanai, Helwak, Takamatsu, Imadome, Takakura, Chanda, Kurosaki, Yamamoto, Ando, Matsui, Inaba, Kotani: "Novel functional small RNAs are selectively loaded onto mammalian Ago1." in: Nucleic acids research, Vol. 42, Issue 8, pp. 5289-301, (2014) (PubMed).

Teta, Choi, Okegbe, Wong, Tam, Chong, Seykora, Nagy, Littman, Andl, Millar: "Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin." in: Development (Cambridge, England), Vol. 139, Issue 8, pp. 1405-16, (2012) (PubMed).

Hsieh, Lin, Liu, Chang, Shih, Zhong, Lee, Tan: "WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway." in: Nucleic acids research, Vol. 39, Issue 10, pp. 4048-62, (2011) (PubMed).

Thomson, Newman, Parker, Morin-Kensicki, Wright, Hammond: "Extensive post-transcriptional regulation of microRNAs and its implications for cancer." in: Genes & development, Vol. 20, Issue 16, pp. 2202-7, (2006) (PubMed).

Synonyms and alternative names related to DROSHA

ribonuclease type III, nuclear (rnasen), Ribonuclease 3 (Thicy_0885), Ribonuclease 3 (Sinme_0866), ribonuclease 3 (Isova_2087), Ribonuclease 3 (Sphch_0770), drosha ribonuclease III (DROSHA), drosha, ribonuclease type III (DROSHA), drosha, ribonuclease type III (Drosha), drosha ribonuclease III (Drosha), 1110013A17Rik, AI874853, ETOHI2, Etohi2, HSA242976, im:7150667, RANSE3L, RGD1307626, RN3, Rn3, RNASE3L, RNASEN, Rnasen, zgc:158612

Protein level used designations for DROSHA

  • drosha
  • ribonuclease 3
  • Ribonuclease 3
  • RNase III
  • drosha, double-stranded RNA-specific endoribonuclease
  • nuclear RNase III Drosha
  • p241
  • protein Drosha
  • putative protein p241 which interacts with transcription factor Sp1
  • putative ribonuclease III
  • ribonuclease III, nuclear
  • ribonuclease type III, nuclear
  • ethanol induced 2
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