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anti-Human RBP4 Antibodies:
anti-Rat (Rattus) RBP4 Antibodies:
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Chicken Monoclonal RBP4 Primary Antibody for IF, IP - ABIN967847
Blomhoff, Green, Berg, Norum: Transport and storage of vitamin A. in Science (New York, N.Y.) 1990
Show all 5 Pubmed References
Mouse (Murine) Polyclonal RBP4 Primary Antibody for WB - ABIN1881735
Wang, Yeh, Wang, Chen, Chuang, Ker, Lee: Decreased retinol binding protein 4 concentrations are associated with cholesterol gallstone disease. in Journal of the Formosan Medical Association = Taiwan yi zhi 2010
Show all 4 Pubmed References
Human Monoclonal RBP4 Primary Antibody for ICC, FACS - ABIN969380
van Hoek, Dehghan, Zillikens, Hofman, Witteman, Sijbrands: An RBP4 promoter polymorphism increases risk of type 2 diabetes. in Diabetologia 2008
Show all 2 Pubmed References
Human Polyclonal RBP4 Primary Antibody for IHC, IHC (p) - ABIN4349659
Kelly, Kashyap, OLeary, Major, Schauer, Kirwan: Retinol-binding protein 4 (RBP4) protein expression is increased in omental adipose tissue of severely obese patients. in Obesity (Silver Spring, Md.) 2010
Show all 2 Pubmed References
Human Polyclonal RBP4 Primary Antibody for ELISA, WB - ABIN188698
Soares, Coelho, Sousa, Batalov, Conceição, Sales-Luís, Ritchie, Williams, Nievergelt, Schork, Saraiva, Buxbaum: Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease. in Human molecular genetics 2005
Rat (Rattus) Polyclonal RBP4 Primary Antibody for ICC, IHC (fro) - ABIN1078484
Zhou, Ye, Li: Expression of retinol binding protein 4 and nuclear factor-κB in diabetic rats with atherosclerosis and the intervention effect of pioglitazone. in Experimental and therapeutic medicine 2016
Human Polyclonal RBP4 Primary Antibody for ELISA, WB - ABIN1169042
Sung, Hong, Suh, Cho, Park, Bae, Park, Han, Song: Role of (-)-epigallocatechin-3-gallate in cell viability, lipogenesis, and retinol-binding protein 4 expression in adipocytes. in Naunyn-Schmiedeberg's archives of pharmacology 2010
Mouse (Murine) Polyclonal RBP4 Primary Antibody for ELISA, WB - ABIN1169044
Chiefari, Paonessa, Iiritano, Le Pera, Palmieri, Brunetti, Lupo, Colantuoni, Foti, Gulletta, De Sarro, Fusco, Brunetti: The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis. in BMC biology 2009
Human Monoclonal RBP4 Primary Antibody for IHC (p), ELISA - ABIN519688
Petta, Tripodo, Grimaudo, Cabibi, Cammà, Di Cristina, Di Marco, Di Vita, Ingrao, Mazzola, Marchesini, Pipitone, Craxì: High liver RBP4 protein content is associated with histological features in patients with genotype 1 chronic hepatitis C and with nonalcoholic steatohepatitis. in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2011
RBP4 (show POLR2D Antibodies) may be associated with higher cardiovascular risk in overweight/obese adolescent girls, but this association is mediated by abdominal obesity.
Bi-allelic mutations in RBP4 (show POLR2D Antibodies) were identified (c.248+1G>A), consistent with a diagnosis of inherited vitamin A deficiency.
Childhood obesity may be associated with variations in RBP4 (show POLR2D Antibodies) gene. The presence of selective SNPs in the RBP4 (show POLR2D Antibodies) gene may account for metabolic complications.
Low levels of vitamin A, E and RBP4 (show POLR2D Antibodies) at the time of renal cell carcinoma (show MOK Antibodies) diagnosis are associated with a poorer prognosis after surgery.
RBP4 (show POLR2D Antibodies) is some 6-fold lower when active TB patients have chronic energy deficiency (CED (show TGFB1 Antibodies)) than when BMI is >25 kg/m sq; however, free fatty acids were not associated with CED (show TGFB1 Antibodies) in active TB patients, which may be a type 2 error or represent an energy impasse where infection and the host's metabolic needs are in competition.
Data show that the tissue-specific expression pattern of human transgenic retinol binding protein 4 (hRBP4orf) was roughly the same as that of mouse Rbp4 (show POLR2D Antibodies).
Elevated levels of RBP4 (show POLR2D Antibodies) are associated with higher cardiovascular mortality among men with type 2 diabetes.
RBP4 (show POLR2D Antibodies) and retinol levels were increased approximately twofold in patients with chronic kidney disease.
RBP4 (show POLR2D Antibodies) level was associated with increased arterial stiffness in young subjects with family history of type 2 diabetes.
Retinol-binding protein 4 is able to function as biomarker to distinguish severe pre-eclampsia from normal pregnancy. More importantly, these results may shed light on the role of Retinol-binding protein 4 in the pathogenesis in pre-eclampsia.
There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found.
RBP4 has a role in adipogenesis of porcine preadipocytes through the insulin (show INS Antibodies) signaling pathways
Data show that there were two genotypes for RBP4 gene in Tibet pig, which did not have significant effect on the reproductive traits.
The aim of this work was to study the effects on litter size of variants of the porcine genes RBP4, ESR1 and IGF2, currently used in genetic tests for different purposes.
Response to selection for increased litter size could not be attributed to effects at the estrogen receptor (show ESR1 Antibodies), retinol-binding protein or follistatin (show FST Antibodies) loci.
study found significant association of two diallelic polymorphisms in the porcine genes for leukaemia inhibitory factor (LIF (show LIF Antibodies)) and retinol-binding protein 4 (RBP4) with number of piglets born alive (NBA) in two German pig lines
The results showed that the polymorphic sites of both PRLR (show PRLR Antibodies) and RBP4 genes are closely related to litter size traits.
progesterone modulates uterine RBP4 mRNA and protein abundance in a time- and concentration-dependent manner.
Two novel single nucleotide polymorphisms (SNPs) and 4-bp deletion mutation of RBP4 gene in Chinese cattle
results suggest that retinol-binding protein 4 is transferred from maternal stores to calves through colostrum
Serum albumin (show ALB Antibodies) and serum retinol-binding protein(sRBP) are not components of bovine interphotoreceptor matrix(IPM). Serum albumin (show ALB Antibodies) and sRBP can not participate in binding and transport of visual cycle retinoids in IPM of bovine retina.
New insights into ghrelin (show GHRL Antibodies) cell physiology, and given the known functions of RBP4 and TTR (show TTR Antibodies), support an emerging role for the ghrelin (show GHRL Antibodies) cell in blood glucose handling and metabolism.
Retinal degeneration in RBP4-Tg mice is RBP4-dependent and light-independent.
Rbp4-deficient mice accumulated retinol in the liver but it was undetectable in the serum, indicating an inverse relation between serum and liver retinol levels. RBP4 is critical for the mobilization of retinol from hepatic storage pools, and such mobilization is necessary for ocular development and visual function.
Hepatocytes Are the Principal Source of Circulating RBP4 in Mice
RBP4 may be a critical modulator promoting the vicious cycle of insulin (show INS Antibodies) resistance and heart failure by activating TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)-mediated inflammatory pathways. Potentially, lowering RBP4 might break the vicious cycle and improve both insulin (show INS Antibodies) resistance and cardiac hypertrophy.
Data (including data from studies in knockout mice) suggest that Rbp4 (plasma retinol-binding protein 4) is critical for antigen presentation and activation of CD4 (show CD4 Antibodies)-positive T-lymphocyte in development of insulin (show INS Antibodies) resistance in mice obese due to high-fat diet.
A novel mechanism for circadian regulation of RBP4, but also a critical role of RBP4, acting as a hepatokine in the regulation of glucose metabolism by the circadian clock.
Elevated serum RBP4 raises BP.
These data show that decreasing circulating TTR (show TTR Antibodies) levels or altering TTR (show TTR Antibodies)-RBP4 binding could be a potential therapeutic approach for the treatment of type 2 diabetes.
findings suggest that RBP4 impaired in vivo adipogenesis, partly through the repression of the insulin (show INS Antibodies) pathway
these data support the model thatretinol binding protein 4 and retinoic acid precursors are present within the CSF (show CSF2 Antibodies) and used for synthesis of retinoic acid, which promotes embryonic neuroepithelial survival
YSL-expressed Rbp4 plays a role in formation of both yolk extension and liver bud, the latter may also require migration of liver progenitor cells
STRA6 deficiency lead to accumulation of RBP-4 bound vitamin A and developmental abnormalities.
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
, plasma retinol-binding protein
, retinol-binding protein 4
, retinol-binding protein 4, interstitial
, retinol-binding protein 4, plasma
, Plasma retinol-binding protein
, retinol binding protein 4, cellular
, serum retinol binding protein