RBP4 antibody

Catalog No. ABIN1169042

There is 1 publication for this product available. The Guinea Pig Polyclonal anti-RBP4 antibody is suitable to detect RBP4 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for RBP4 antibody (ABIN1169042)

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reactivity: Human

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This RBP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RBP4 Antibody

Purpose: anti-RBP4 (human), pAb

Specificity: Recognizes human RBP4. Detects a band of ~22-25 kDa by Western blot. Weakly cross-reacts with mouse and rat RBP4.

Cross-Reactivity (Details): Weakly cross-reacts with mouse and rat RBP4.

Characteristics: Polyclonal Antibody. Recognizes human RBP4. Detects a band of ~22-25 kDa by Western blot. Weakly cross-reacts with mouse and rat RBP4. Source: Guinea pig. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human RBP4.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

References for anti-RBP4 antibody (ABIN1169042)

Sung, Hong, Suh, Cho, Park, Bae, Park, Han, Song: "Role of (-)-epigallocatechin-3-gallate in cell viability, lipogenesis, and retinol-binding protein 4 expression in adipocytes." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 382, Issue 4, pp. 303-10, (2010) (PubMed).

Target Details for RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: RBP4

Background:

Alternate Names/Synonyms: Retinol Binding Protein 4

Product Description: Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response