RBP4 antibody

Catalog No. ABIN1169044

This Rabbit Polyclonal antibody specifically detects RBP4 in WB and ELISA. It exhibits reactivity toward Mouse.It has been mentioned in 1 publication

Quick Overview for RBP4 antibody (ABIN1169044)

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RBP4 Antibody

Purpose: anti-RBP4 (mouse), pAb

Specificity: Recognizes mouse RBP4. Detects a band of ~22-25 kDa by Western blot.

Characteristics: Polyclonal Antibody. Recognizes mouse RBP4. Detects a band of ~22-25 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse RBP4.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

References for anti-RBP4 antibody (ABIN1169044)

Chiefari, Paonessa, Iiritano, Le Pera, Palmieri, Brunetti, Lupo, Colantuoni, Foti, Gulletta, De Sarro, Fusco, Brunetti: "The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis." in: BMC biology, Vol. 7, pp. 24, (2009) (PubMed).

Target Details for RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: RBP4

Background:

Alternate Names/Synonyms: Retinol Binding Protein 4

Product Description: Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

UniProt: Q00724

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response