Browse our anti-EZH2 (EZH2) Antibodies

Full name:
anti-Enhancer of Zeste Homolog 2 (Drosophila) Antibodies (EZH2)
On are 233 Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) Antibodies from 30 different suppliers available. Additionally we are shipping EZH2 Kits (22) and EZH2 Proteins (8) and many more products for this protein. A total of 275 EZH2 products are currently listed.
Enx-1, ENX1, Enx1h, eya2, EZH1, ezh2, EZH2b, im:7149338, KMT6, KMT6A, mKIAA4065, olezh2, WVS, WVS2, xez, zgc:136376, zgc:152758
list all antibodies Gene Name GeneID UniProt
EZH2 2146 Q15910
EZH2 14056 Q61188
EZH2 312299  

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Top referenced anti-EZH2 Antibodies

  1. Human Polyclonal EZH2 Primary Antibody for ChIPSeq, ChIP - ABIN2668958 : Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ... in Molecular cancer therapeutics 2014 (PubMed)
    Show all 9 references for 2668958

  2. Human Monoclonal EZH2 Primary Antibody for ChIP - ABIN2668955 : Bengani, Mendiratta, Maini, Vasanthi, Sultana, Ghasemi, Ahluwalia, Ramachandran, Mishra, Brahmachari: Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. in PLoS ONE 2013 (PubMed)
    Show all 8 references for 2668955

  3. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668957 : Izzo, Mercogliano, Venturutti, Tkach, Inurrigarro, Schillaci, Cerchietti, Elizalde, Proietti: Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. in Breast cancer research : BCR 2015 (PubMed)
    Show all 7 references for 2668957

  4. Human Monoclonal EZH2 Primary Antibody for IF, IHC (p) - ABIN659002 : Tsai, Manor, Wan, Mosammaparast, Wang, Lan, Shi, Segal, Chang: Long noncoding RNA as modular scaffold of histone modification complexes. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 6 references for 659002

  5. Chicken Monoclonal EZH2 Primary Antibody for IF, WB - ABIN968906 : Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 references for 968906

  6. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668964 : Kaneko, Li, Son, Xu, Margueron, Neubert, Reinberg: Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. in Genes & development 2010 (PubMed)
    Show all 2 references for 2668964

  7. Human Polyclonal EZH2 Primary Antibody for ICC, IF - ABIN438771 : Hyland, McDade, McCloskey, Dickson, Arthur, McCance, Patel: Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. in Journal of virology 2011 (PubMed)

More Antibodies against EZH2 Interaction Partners

Xenopus laevis Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 leads to reduced retinal progenitor proliferation.

Human Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. that EZH2 is phosphorylated by the DNA damage responsive complex DNA-PK and regulates DNA damage-mediated T-cell apoptosis.

  2. EZH2 mutations were mostly early events in leukemogenesis and showed a complex mutational hierarchy

  3. The EZH2 was recruited to the IRF8 (show IRF8 Antibodies) promoter after RANKL (show TNFSF11 Antibodies) stimulation to deposit the negative histone mark H3K27me3 and downregulate IRF8 (show IRF8 Antibodies) expression.

  4. Authors demonstrate that inhibition of the non-canonical NF-kB pathway by targeting NF-kB2/p52 (show NFKB2 Antibodies) or the upstream kinase NIK (show MAP3K14 Antibodies) restores the senescence program in melanoma cells through the decrease of EZH2.

  5. The data suggest that EZH2-H3K27me3 regulatory mechanism dynamically changes the expression levels of DNA mismatch repair gene MutS homolog 2 (show MSH2 Antibodies), through epigenetic mark H3K27me3.

  6. TRIM28 (show TRIM28 Antibodies) depletion repressed EZH2 recruitment to chromatin and expression of this gene set, in parallel with decreased CD44 (show CD44 Antibodies)(hi)/CD24 (show CD24 Antibodies)(lo) mammosphere formation.

  7. EZH2 overexpression is significantly associated with inferior outcome in patients with primary gastrointestinal diffuse large B-cell lymphoma.

  8. High EZH2 expression is associated with liver neoplasms.

  9. EZH2 not only acts through the direct regulation of signaling modules and lineage-specific transcription factors but also targets many novel genes important for mediating mesenchymal stem cell osteogenic differentiation.

  10. EZH2 expression was associated with survival in patients with colorectal cancer who were treated with anti-EGFR (show EGFR Antibodies) therapeutics. Moreover, low EZH2 expression was independently associated with shorter progression-free survival in patients with cancer, suggesting that EZH2 expression is a useful additional prognostic biomarker for anti-EGFR (show EGFR Antibodies) therapy.

Mouse (Murine) Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. results uncover a crucial role for EZH2 in adaptive lymphocytes to control the developmental timing of effectors of the pre-Ag receptor checkpoints

  2. These findings identify the Ezh2-Hsp90 (show HSP90 Antibodies) interaction as a previously unrecognized mechanism essential for T-cell responses and an effective target for controlling graft-versus-host disease.

  3. Eed (show EED Antibodies) and Ezh2 have distinct roles in urothelial differentiation

  4. Findings uncover an Ezh2-dependent mechanism to restrict the smooth muscle gene expression program in the developing mesothelium and allow appropriate cell fate decisions to occur in this multipotent mesoderm lineage.

  5. The evidence has been presented that the retinoblastoma protein utilizes a cell-cycle-independent interaction with E2F1 (show E2F1 Antibodies) to recruit EZH2 to diverse repeat sequences.

  6. This study identified Ezh2 as enriched in melanoma cancer stem cells (MCS (show SMCP Antibodies) cells) and showed that Ezh2 knockdown or treatment with small molecule Ezh2 inhibitors reduces MCS (show SMCP Antibodies) cell spheroid formation, survival, invasion and migration.

  7. Ezh2-/- deletion resulted in skeletal deformities, increased osteoclastogenic potential and upregulation of Rankl (show TNFSF11 Antibodies) and M-csf (show CSF1R Antibodies) expression by mesenchymal stem cells.

  8. These findings indicate Ezh2/PRC2 plays crucial roles in regulating neurogenesis from both cerebellar germinal zones.

  9. our results revealed a novel mechanism in which EZH2 stability is regulated by SKP2 through the TRAF6 (show TRAF6 Antibodies)-mediated and K63-linked ubiquitination, which contributes to elevated levels of H3K27me3 during prostate tumorigenesis and CRPC growth.

  10. N-Myc (show MYCN Antibodies) Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer and redirects EZH2 activity and sensitizes cells to EZH2 inhibitors.

EZH2 Antigen Profile

Antigen Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with EZH2

  • enhancer of zeste homolog 2 (Drosophila) (EZH2) antibody
  • enhancer of zeste homolog 2 (ezh2) antibody
  • enhancer of zeste homolog 2 (ezh2-a) antibody
  • enhancer of zeste homolog 2 (Drosophila) (Ezh2) antibody
  • enhancer of zeste homolog 2 (Drosophila) (ezh2) antibody
  • Enx-1 antibody
  • ENX1 antibody
  • Enx1h antibody
  • eya2 antibody
  • EZH1 antibody
  • ezh2 antibody
  • EZH2b antibody
  • im:7149338 antibody
  • KMT6 antibody
  • KMT6A antibody
  • mKIAA4065 antibody
  • olezh2 antibody
  • WVS antibody
  • WVS2 antibody
  • xez antibody
  • zgc:136376 antibody
  • zgc:152758 antibody

Protein level used designations for EZH2

enhancer of zeste 2 , enhancer of zeste homolog 2 (Drosophila) , Polycomb protein EZH2 , histone-lysine N-methyltransferase EZH2 , histone-lysine N-methyltransferase EZH2-like , Enhancer of zeste homolog 2-A , Polycomb protein EZH2-A , lysine N-methyltransferase 6 , enhancer of zeste homolog 2 , eyes absent homolog 2

745437 Pan troglodytes
100051290 Equus caballus
550047 Xenopus (Silurana) tropicalis
709075 Macaca mulatta
100125823 Oryzias latipes
100394758 Callithrix jacchus
100447447 Pongo abelii
100540374 Meleagris gallopavo
100580962 Nomascus leucogenys
399174 Xenopus laevis
2146 Homo sapiens
14056 Mus musculus
420784 Gallus gallus
475511 Canis lupus familiaris
100625497 Sus scrofa
509106 Bos taurus
312299 Rattus norvegicus
768133 Danio rerio
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