Browse our anti-EZH2 (EZH2) Antibodies

Full name:
anti-Enhancer of Zeste Homolog 2 (Drosophila) Antibodies (EZH2)
On www.antibodies-online.com are 224 Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) Antibodies from 30 different suppliers available. Additionally we are shipping EZH2 Kits (22) and EZH2 Proteins (8) and many more products for this protein. A total of 266 EZH2 products are currently listed.
Synonyms:
Enx-1, ENX1, Enx1h, eya2, EZH1, ezh2, EZH2b, im:7149338, KMT6, KMT6A, mKIAA4065, olezh2, WVS, WVS2, xez, zgc:136376, zgc:152758
list all antibodies Gene Name GeneID UniProt
EZH2 2146 Q15910
EZH2 14056 Q61188
EZH2 312299  

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Top referenced anti-EZH2 Antibodies

  1. Human Polyclonal EZH2 Primary Antibody for ChIPSeq, ChIP - ABIN2668958 : Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ... in Molecular cancer therapeutics 2014 (PubMed)
    Show all 6 references for 2668958

  2. Human Monoclonal EZH2 Primary Antibody for IF, IHC (p) - ABIN659002 : Tsai, Manor, Wan, Mosammaparast, Wang, Lan, Shi, Segal, Chang: Long noncoding RNA as modular scaffold of histone modification complexes. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 6 references for 659002

  3. Human Monoclonal EZH2 Primary Antibody for ChIP - ABIN2668955 : Bengani, Mendiratta, Maini, Vasanthi, Sultana, Ghasemi, Ahluwalia, Ramachandran, Mishra, Brahmachari: Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. in PLoS ONE 2013 (PubMed)
    Show all 6 references for 2668955

  4. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668957 : Izzo, Mercogliano, Venturutti, Tkach, Inurrigarro, Schillaci, Cerchietti, Elizalde, Proietti: Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. in Breast cancer research : BCR 2015 (PubMed)
    Show all 4 references for 2668957

  5. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668964 : Kaneko, Li, Son, Xu, Margueron, Neubert, Reinberg: Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. in Genes & development 2010 (PubMed)
    Show all 2 references for 2668964

  6. Chicken Monoclonal EZH2 Primary Antibody for IF, WB - ABIN968906 : Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 references for 968906

  7. Human Polyclonal EZH2 Primary Antibody for ICC, IF - ABIN438771 : Hyland, McDade, McCloskey, Dickson, Arthur, McCance, Patel: Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. in Journal of virology 2011 (PubMed)

More Antibodies against EZH2 Interaction Partners

Xenopus laevis Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 leads to reduced retinal progenitor proliferation.

Human Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. our results revealed a novel mechanism in which EZH2 stability is regulated by SKP2 through the TRAF6 (show TRAF6 Antibodies)-mediated and K63-linked ubiquitination, which contributes to elevated levels of H3K27me3 during prostate tumorigenesis and CRPC growth.

  2. Our results showed EZH2 to be highly overexpressed in astrocytic tumors with a significant positive correlation with grade.we identified SLC25A23 (show SLC25A24 Antibodies) as important target of H3K27me3 modification, which was downregulated in GBM and its low expression was associated with poor prognosis in glioblastomas (GBMs).

  3. EZH2 may mediate, at least partially, the senescence-inducing effects of lidamycin by regulating p21 (show CDKN1A Antibodies) expression and DNA damage effect.

  4. These results illustrate that EZH2 may promote carcinogenesis and cancer development of nasopharyngeal carcinoma by transcriptional repression of XPA (show XPA Antibodies) gene and inactivation of nucleotide excision repair pathway.

  5. Data show that EZH2 plays a critical role in the FMR1 (show FMR1 Antibodies) gene silencing process and that its inhibition can prolong expression of the FMR1 (show FMR1 Antibodies) gene even in the presence of its transcript.

  6. N-Myc (show MYCN Antibodies) Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer and redirects EZH2 activity and sensitizes cells to EZH2 inhibitors.

  7. BAP1 (show RNF2 Antibodies) loss and high EZH2 expression were highly specific to malignant mesothelioma in differentiating it from benign mesothelial proliferations

  8. Loss of the histone methyltransferase EZH2 and subsequent reduction of histone H3K27 trimethylation is a novel pathway of acquired resistance to tyrosine kinase (show TXK Antibodies) inhibitors (TKIs) and cytotoxic drugs in acute myeloid leukemia (show BCL11A Antibodies).

  9. No EZH2 Y646 mutations were identified among the 82 sporadic parathyroid adenomas. Furthermore, no copy number variations of EZH2 were found in any of the 61 parathyroid adenomas analyzed.

  10. Residual PRC2 activity, via EZH2 binding to mutant H3K27M histones, is required for the proliferation of H3K27M-expressing diffuse intrinsic pontine gliomas.

Mouse (Murine) Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. These findings indicate Ezh2/PRC2 plays crucial roles in regulating neurogenesis from both cerebellar germinal zones.

  2. our results revealed a novel mechanism in which EZH2 stability is regulated by SKP2 through the TRAF6 (show TRAF6 Antibodies)-mediated and K63-linked ubiquitination, which contributes to elevated levels of H3K27me3 during prostate tumorigenesis and CRPC growth.

  3. N-Myc (show MYCN Antibodies) Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer and redirects EZH2 activity and sensitizes cells to EZH2 inhibitors.

  4. we propose that through its control of PLZF (show ZBTB16 Antibodies) concentration, Ezh2 maintains NKT (show CTSL1 Antibodies) cell numbers at appropriate levels and facilitates immune homeostasis. We believe that our study establishes a paradigm for alternative roles of Ezh2 and non-histone methylation in the regulation of cell fate determination.

  5. Residual PRC2 activity, via EZH2 binding to mutant H3K27M histones, is required for the proliferation of H3K27M-expressing diffuse intrinsic pontine gliomas.

  6. EZH2 is part of the protein machinery that shapes the aging epigenome.

  7. S6K1 (show RPS6KB1 Antibodies) phosphorylation of H2B mediates EZH2 trimethylation of H3 early in adipogenesis, contributing to the promotion of obesity.

  8. results suggest that loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in Jak2V617F

  9. JAK2 (show JAK2 Antibodies)-V617F-expressing mice treated with an Ezh2 inhibitor showed higher platelet counts than vehicle controls. Our data support the proposed tumor suppressor function of EZH2

  10. an EZH2 insufficiency not only cooperated with active JAK2 (show JAK2 Antibodies) to induce MF, but also conferred an oncogenic addiction to the H3K27ac modification in primary myelofibrosis -initiating cells that was capable of being restored by bromodomain inhibition.

EZH2 Antigen Profile

Antigen Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with EZH2

  • enhancer of zeste homolog 2 (Drosophila) (EZH2) antibody
  • enhancer of zeste homolog 2 (ezh2) antibody
  • enhancer of zeste homolog 2 (ezh2-a) antibody
  • enhancer of zeste homolog 2 (Drosophila) (Ezh2) antibody
  • enhancer of zeste homolog 2 (Drosophila) (ezh2) antibody
  • Enx-1 antibody
  • ENX1 antibody
  • Enx1h antibody
  • eya2 antibody
  • EZH1 antibody
  • ezh2 antibody
  • EZH2b antibody
  • im:7149338 antibody
  • KMT6 antibody
  • KMT6A antibody
  • mKIAA4065 antibody
  • olezh2 antibody
  • WVS antibody
  • WVS2 antibody
  • xez antibody
  • zgc:136376 antibody
  • zgc:152758 antibody

Protein level used designations for EZH2

enhancer of zeste 2 , enhancer of zeste homolog 2 (Drosophila) , Polycomb protein EZH2 , histone-lysine N-methyltransferase EZH2 , histone-lysine N-methyltransferase EZH2-like , Enhancer of zeste homolog 2-A , Polycomb protein EZH2-A , lysine N-methyltransferase 6 , enhancer of zeste homolog 2 , eyes absent homolog 2

GENE ID SPECIES
745437 Pan troglodytes
100051290 Equus caballus
550047 Xenopus (Silurana) tropicalis
709075 Macaca mulatta
100125823 Oryzias latipes
100394758 Callithrix jacchus
100447447 Pongo abelii
100540374 Meleagris gallopavo
100580962 Nomascus leucogenys
399174 Xenopus laevis
2146 Homo sapiens
14056 Mus musculus
420784 Gallus gallus
475511 Canis lupus familiaris
100625497 Sus scrofa
509106 Bos taurus
312299 Rattus norvegicus
768133 Danio rerio
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