Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human EZH2 Antibodies:
anti-Mouse (Murine) EZH2 Antibodies:
anti-Rat (Rattus) EZH2 Antibodies:
Go to our pre-filtered search.
Human Polyclonal EZH2 Primary Antibody for ChIPSeq, ChIP - ABIN2668958
Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ... in Molecular cancer therapeutics 2014
Show all 9 Pubmed References
Human Monoclonal EZH2 Primary Antibody for ChIP - ABIN2668955
Bengani, Mendiratta, Maini, Vasanthi, Sultana, Ghasemi, Ahluwalia, Ramachandran, Mishra, Brahmachari: Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. in PLoS ONE 2013
Show all 8 Pubmed References
Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668957
Izzo, Mercogliano, Venturutti, Tkach, Inurrigarro, Schillaci, Cerchietti, Elizalde, Proietti: Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. in Breast cancer research : BCR 2015
Show all 7 Pubmed References
Polyclonal EZH2 Primary Antibody for WB - ABIN540724
Hobert, Jallal, Ullrich: Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression. in Molecular and cellular biology 1996
Show all 3 Pubmed References
Chicken Monoclonal EZH2 Primary Antibody for IF, WB - ABIN968906
Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 2 Pubmed References
Chicken Monoclonal EZH2 Primary Antibody for IF, WB - ABIN968907
van Kemenade, Raaphorst, Blokzijl, Fieret, Hamer, Satijn, Otte, Meijer: Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma. in Blood 2001
Show all 2 Pubmed References
Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668964
Kaneko, Li, Son, Xu, Margueron, Neubert, Reinberg: Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. in Genes & development 2010
Show all 2 Pubmed References
Human Polyclonal EZH2 Primary Antibody for ICC, IF - ABIN438771
Hyland, McDade, McCloskey, Dickson, Arthur, McCance, Patel: Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. in Journal of virology 2011
Human Monoclonal EZH2 Primary Antibody for IF, IHC (p) - ABIN659002
Tsai, Manor, Wan, Mosammaparast, Wang, Lan, Shi, Segal, Chang: Long noncoding RNA as modular scaffold of histone modification complexes. in Science (New York, N.Y.) 2010
Show all 6 Pubmed References
Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 leads to reduced retinal progenitor proliferation.
Transwell invasion assay, wound healing assay and flow cytometry results showed that the inhibition of EZH2 or the up-regulation of miR (show MLXIP Antibodies)-101-3p inhibited the viability, migration, invasion and cell cycle but promoted cell apoptosis of lung squamous cell carcinoma.
inactivating mutations of KDM6A (show KDM6A Antibodies), which are common in urothelial bladder carcinoma, are potentially targetable by inhibiting EZH2.
Loss of PRC2-mediated gene expression is accompanied by up-regulation of EZH2 and HIF1A (show HIF1A Antibodies) in breast cancer.
Combination of TPA (show PLAT Antibodies) with GSK126, an inhibitor of the catalytic activity of EZH2, has a synergic effect on the induction of muscle differentiation in embryonal rhabdomyosarcoma cells.
decline in HDAC9c expression over time was accompanied by increased EZH2 expression.
TT genotype of EZH2 (rs2072408) was associated with lymph node metastasis and the depth of gastric wall invasion in patients with gastric cancer.
Results show that EZH2 is a direct target of miR (show MLXIP Antibodies)-101 and an inverse relationship was found between lncRNA XIST and miR (show MLXIP Antibodies)-101 where lncRNA XIST exerted its tumor-suppressive effects at least in part through regulating miR (show MLXIP Antibodies)-101 to modulate EZH2 expression.
Overexpression of the wild-type TET1 (show TET1 Antibodies)/2/3 3'UTR (show UTS2R Antibodies) caused a significant increase in EZH2 expression and tumor growth, whereas the mutation in miR (show MLXIP Antibodies)-26-binding sites abolished this effect.
The EZH2-mediated change in the epigenome of oral squamous cell carcinoma cells induces upregulation of ROS1 and its target genes, conferring greater invasiveness and plasticity to cope with the tumor microenvironment.
Long non-coding RNA LOC554202 may play an important role in the progression of chordoma by the direct upregulation of EZH2 and indirect promotion of RNF144B (show RNF144B Antibodies) via miR (show MLXIP Antibodies)-31
Gfi1 (show ZNF163 Antibodies) disruption antagonized the tumor-promoting effects of Ezh2 loss; conversely, Gfi1 (show ZNF163 Antibodies) overexpression collaborated with Myc (show MYC Antibodies) to bypass effects of Trp53 (show TP53 Antibodies) inactivation in driving medulloblastoma progression in primary cerebellar neuronal progenitors.
EZH2-deficient hESCs can initiate differentiation toward developmental lineages; however, they cannot fully differentiate into mature specialized tissues. Thus, EZH2 is required for stable ESC self-renewal, regulation of transcriptional programs, and for late-stage differentiation in this model of early human development.
we found that the miRNA biogenesis enzyme DICER was required for the binding of the PRC2 core components EZH2 and SUZ12, and for the presence of the PRC2-mediated histone modification H3K27me3 at many bivalent genes
High EZH2 expression is associated with Neuroblastoma (show ARHGEF16 Antibodies).
Biochemical as well as functional experiments revealed that Spt6 could compete for binding of the PRC2 methyltransferase Ezh2 to Suz12 and reduce PRC2 chromatin engagement.
These findings indicate that Ezh2 targets are the major targets of the epigenetic switch in MDS (show MECOM Antibodies) with Ezh2 insufficiency.
Insight regarding how androgen-induced extranuclear kinase signaling and intranuclear transcription through Ezh2 modifications may influence the expression pattern of genes, ultimately affecting various downstream physiological processes.
results uncover a crucial role for EZH2 in adaptive lymphocytes to control the developmental timing of effectors of the pre-Ag receptor checkpoints
ezh2-deficient mutants fail to properly regenerate their spinal cord after caudal (show CAD Antibodies) fin transection suggesting that Ezh2 and H3K27me3 methylation might also be involved in the process of regeneration in zebrafish.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
enhancer of zeste 2
, enhancer of zeste homolog 2 (Drosophila)
, Polycomb protein EZH2
, histone-lysine N-methyltransferase EZH2
, histone-lysine N-methyltransferase EZH2-like
, Enhancer of zeste homolog 2-A
, Polycomb protein EZH2-A
, lysine N-methyltransferase 6
, enhancer of zeste homolog 2
, eyes absent homolog 2