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Browse our anti-EZH2 (EZH2) Antibodies

Full name:
anti-Enhancer of Zeste Homolog 2 (Drosophila) Antibodies (EZH2)
On www.antibodies-online.com are 225 Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) Antibodies from 31 different suppliers available. Additionally we are shipping EZH2 Kits (22) and EZH2 Proteins (8) and many more products for this protein. A total of 267 EZH2 products are currently listed.
Synonyms:
Enx-1, ENX1, Enx1h, eya2, EZH1, ezh2, EZH2b, im:7149338, KMT6, KMT6A, mKIAA4065, olezh2, WVS, WVS2, xez, zgc:136376, zgc:152758
list all antibodies Gene Name GeneID UniProt
EZH2 2146 Q15910
EZH2 14056 Q61188
EZH2 312299  

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Most Popular Reactivities for anti-EZH2 (EZH2) Antibodies

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anti-Human EZH2 Antibodies:

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anti-Rat (Rattus) EZH2 Antibodies:

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Top referenced anti-EZH2 Antibodies

  1. Human Monoclonal EZH2 Primary Antibody for IF, IHC (p) - ABIN659002 : Tsai, Manor, Wan, Mosammaparast, Wang, Lan, Shi, Segal, Chang: Long noncoding RNA as modular scaffold of histone modification complexes. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 6 references for ABIN659002

  2. Human Polyclonal EZH2 Primary Antibody for ChIPSeq, ChIP - ABIN2668958 : Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ... in Molecular cancer therapeutics 2014 (PubMed)
    Show all 6 references for ABIN2668958

  3. Human Monoclonal EZH2 Primary Antibody for ChIP - ABIN2668955 : Bengani, Mendiratta, Maini, Vasanthi, Sultana, Ghasemi, Ahluwalia, Ramachandran, Mishra, Brahmachari: Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. in PLoS ONE 2013 (PubMed)
    Show all 6 references for ABIN2668955

  4. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668957 : Izzo, Mercogliano, Venturutti, Tkach, Inurrigarro, Schillaci, Cerchietti, Elizalde, Proietti: Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. in Breast cancer research : BCR 2015 (PubMed)
    Show all 4 references for ABIN2668957

  5. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668964 : Kaneko, Li, Son, Xu, Margueron, Neubert, Reinberg: Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. in Genes & development 2010 (PubMed)
    Show all 2 references for ABIN2668964

  6. Chicken Monoclonal EZH2 Primary Antibody for IF, WB - ABIN968906 : Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 references for ABIN968906

  7. Human Polyclonal EZH2 Primary Antibody for ICC, IF - ABIN438771 : Hyland, McDade, McCloskey, Dickson, Arthur, McCance, Patel: Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. in Journal of virology 2011 (PubMed)

More Antibodies against EZH2 Interaction Partners

Xenopus laevis Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 leads to reduced retinal progenitor proliferation.

Human Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. EZH2 and ZFX genes do not seem to have an impact on the onset of most parathyroid tumours, both benign and malignant, though further studies on larger cohorts of different ethnicity are needed.

  2. BRD4 (show BRD4 Antibodies) positively regulates EZH2 transcription through upregulation of C-MYC (show MYC Antibodies), and is a novel promising target for pharmacologic treatment in transcriptional program intervention against this intractable disease.

  3. findings suggest that EZH2 possesses anti-apoptotic activity in gastric tumorigenesis following STAT3 (show STAT3 Antibodies) activation

  4. Inhibition of EZH2 (by GSK-343 or EPZ-6438) or inhibition of EHMT2 (show EHMT2 Antibodies) (by UNC-0638) in the Th17 primary cell model of HIV latency or resting memory T cells isolated from HIV-1-infected patients receiving highly active antiretroviral therapy, was sufficient to induce the reactivation of latent proviruses.

  5. Data indicate that enhancer of zeste homolog 2 (Drosophila) protein (EZH2) is a direct target of microRNA miR (show MLXIP Antibodies)-126 and restoration of EZH2 expression blocks the suppressive roles of miR (show MLXIP Antibodies)-126.

  6. the functional association between EZH2 expression and silencing of key tumor suppressor loci , was investigated.

  7. H19 (show NCKAP1 Antibodies) inhibited E-cadherin (show CDH1 Antibodies) expression and promoted cell invasion of NPC (show NPC1 Antibodies) cells via the miR (show MLXIP Antibodies)-630/EZH2 pathway

  8. We also showed that knockdown of urothelial carcinoma-associated 1 increased the p21 protein (show NRAS Antibodies) expression through regulating enhancer of zeste homolog 2. In addition, bioinformatics analysis and dual-luciferase reporter assays confirmed that miR (show MLXIP Antibodies)-495 was a target of urothelial carcinoma-associated 1 in renal cell carcinoma (show MOK Antibodies), and urothelial carcinoma-associated 1 promoted cell proliferation by negatively regulating miR (show MLXIP Antibodies)-495

  9. EZH2, through a methyltransferase-independent mechanism, promotes the transcriptional activation of the non-canonical NF-kappaB (show NFKB1 Antibodies) subunit RelB (show RELB Antibodies)

  10. enhancer of zeste homolog 2 (EZH2) accounts for the silence of 11beta-HSD2 (show HSD11B2 Antibodies) expression via trimethylation of histone H3 (show HIST3H3 Antibodies) lysine 27 at the promoter of the 11beta-HSD2 (show HSD11B2 Antibodies) gene.

Mouse (Murine) Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. the functional association between EZH2 expression and silencing of key tumor suppressor loci , was investigated.

  2. Menin (show MEN1 Antibodies) binds on the promoter of Inhbb (show INHBB Antibodies) gene where it favours the recruitment of Ezh2 via an indirect mechanism involving Akt (show AKT1 Antibodies)-phosphorylation.

  3. EZH2 directly interacted with and stabilized BubR1 (show BUB1B Antibodies), an effect driving EZH2 into the concert of meiosis regulation.

  4. A long noncoding RNA, lnc-beta-Catm, elicits EZH2-dependent beta-catenin (show CTNNB1 Antibodies) stabilization and sustains liver cancer stem cells self-renewal.

  5. these results suggest that the inflammatory milieu found in Crohn's disease could lead to or result from deregulation of FOXP3 (show FOXP3 Antibodies)/EZH2-enforced T cell gene networks contributing to the underlying intestinal inflammation.

  6. Data show that enhancer of zeste 2 polycomb (show CBX2 Antibodies) repressive complex 2 subunit (EZH2-containing PRC2) is required for differentiation of terminal effector CD8 (show CD8A Antibodies)+ T cells.

  7. these data suggest that inhibition of Ezh2 promotes paracrine signaling in osteoblasts a

  8. demonstrate that a specific interaction between the polycomb protein EZH2 and RNA made from B2 SINE retrotransposons controls stress-responsive genes in mouse cells. In the heat-shock model, B2 RNA binds stress genes and suppresses their transcription. Upon stress, EZH2 is recruited and triggers cleavage of B2 RNA. B2 degradation in turn upregulates stress genes.

  9. The Ezh2 expression could be clearly seen in outer and inner hair cells, supporting cells, the stria vascularis, and spiral ganglion cells. Ezh2 continued to be expressed in the cochlear epithelium of adult mice.

  10. Genetic inactivation of Ezh2 or Eed (show EED Antibodies) cooperates with NRASQ61K in leukemogenesis.

EZH2 Antigen Profile

Antigen Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with EZH2

  • enhancer of zeste homolog 2 (Drosophila) (EZH2) antibody
  • enhancer of zeste homolog 2 (ezh2) antibody
  • enhancer of zeste homolog 2 (ezh2-a) antibody
  • enhancer of zeste homolog 2 (Drosophila) (Ezh2) antibody
  • enhancer of zeste homolog 2 (Drosophila) (ezh2) antibody
  • Enx-1 antibody
  • ENX1 antibody
  • Enx1h antibody
  • eya2 antibody
  • EZH1 antibody
  • ezh2 antibody
  • EZH2b antibody
  • im:7149338 antibody
  • KMT6 antibody
  • KMT6A antibody
  • mKIAA4065 antibody
  • olezh2 antibody
  • WVS antibody
  • WVS2 antibody
  • xez antibody
  • zgc:136376 antibody
  • zgc:152758 antibody

Protein level used designations for EZH2

enhancer of zeste 2 , enhancer of zeste homolog 2 (Drosophila) , Polycomb protein EZH2 , histone-lysine N-methyltransferase EZH2 , histone-lysine N-methyltransferase EZH2-like , Enhancer of zeste homolog 2-A , Polycomb protein EZH2-A , lysine N-methyltransferase 6 , enhancer of zeste homolog 2 , eyes absent homolog 2

GENE ID SPECIES
745437 Pan troglodytes
100051290 Equus caballus
550047 Xenopus (Silurana) tropicalis
709075 Macaca mulatta
100125823 Oryzias latipes
100394758 Callithrix jacchus
100447447 Pongo abelii
100540374 Meleagris gallopavo
100580962 Nomascus leucogenys
399174 Xenopus laevis
2146 Homo sapiens
14056 Mus musculus
420784 Gallus gallus
475511 Canis lupus familiaris
100625497 Sus scrofa
509106 Bos taurus
312299 Rattus norvegicus
768133 Danio rerio
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