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Browse our anti-EZH2 (EZH2) Antibodies

Full name:
anti-Enhancer of Zeste Homolog 2 (Drosophila) Antibodies (EZH2)
On www.antibodies-online.com are 221 Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) Antibodies from 32 different suppliers available. Additionally we are shipping EZH2 Kits (17) and EZH2 Proteins (8) and many more products for this protein. A total of 258 EZH2 products are currently listed.
Synonyms:
Enx-1, ENX1, Enx1h, eya2, EZH1, ezh2, EZH2b, im:7149338, KMT6, KMT6A, mKIAA4065, olezh2, WVS, WVS2, xez, zgc:136376, zgc:152758
list all antibodies Gene Name GeneID UniProt
EZH2 2146 Q15910
EZH2 14056 Q61188
EZH2 312299  

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Most Popular Reactivities for anti-EZH2 (EZH2) Antibodies

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anti-Human EZH2 Antibodies:

anti-Mouse (Murine) EZH2 Antibodies:

anti-Rat (Rattus) EZH2 Antibodies:

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Top referenced anti-EZH2 Antibodies

  1. Human Monoclonal EZH2 Primary Antibody for IF, IHC (p) - ABIN659002 : Tsai, Manor, Wan, Mosammaparast, Wang, Lan, Shi, Segal, Chang: Long noncoding RNA as modular scaffold of histone modification complexes. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 6 references for ABIN659002

  2. Human Polyclonal EZH2 Primary Antibody for ChIPSeq, ChIP - ABIN2668958 : Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ... in Molecular cancer therapeutics 2014 (PubMed)
    Show all 6 references for ABIN2668958

  3. Human Monoclonal EZH2 Primary Antibody for ChIP - ABIN2668955 : Bengani, Mendiratta, Maini, Vasanthi, Sultana, Ghasemi, Ahluwalia, Ramachandran, Mishra, Brahmachari: Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. in PLoS ONE 2013 (PubMed)
    Show all 6 references for ABIN2668955

  4. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668957 : Izzo, Mercogliano, Venturutti, Tkach, Inurrigarro, Schillaci, Cerchietti, Elizalde, Proietti: Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. in Breast cancer research : BCR 2015 (PubMed)
    Show all 4 references for ABIN2668957

  5. Chicken Monoclonal EZH2 Primary Antibody for IF, WB - ABIN968906 : Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 references for ABIN968906

  6. Human Polyclonal EZH2 Primary Antibody for WB - ABIN2668964 : Kaneko, Li, Son, Xu, Margueron, Neubert, Reinberg: Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. in Genes & development 2010 (PubMed)
    Show all 2 references for ABIN2668964

  7. Human Polyclonal EZH2 Primary Antibody for ICC, IF - ABIN438771 : Hyland, McDade, McCloskey, Dickson, Arthur, McCance, Patel: Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. in Journal of virology 2011 (PubMed)

More Antibodies against EZH2 Interaction Partners

Xenopus laevis Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 leads to reduced retinal progenitor proliferation.

Human Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. MiR (show MLXIP Antibodies)-203 may contribute to the metastasis and enhance apoptosis of hepatocellular carcinoma cells by regulating EZH2 and Bmi-1 (show BMI1 Antibodies) expression.

  2. We found a novel heterozygous EZH2 mutation within exon 5 that caused an amino acid change from proline to leucine at position 132 (p.Pro132Leu) within the catalytic D1 domain. Analysis of a remission sample also showed this mutation, indicating a germline mutation.

  3. Suppression of EHZ2 using lentiviral small hairpin RNA inhibited hepatoblastoma cell proliferation, induced cell cycle arrest in G1 phase and enhanced the expression of G1/Sphase checkpoint protein p27 (show PAK2 Antibodies).

  4. Notch1 (show NOTCH1 Antibodies) and EZH2 coexpression contributes to the progression and prognosis of breast invasive ductal carcinoma.

  5. Mutating or deleting EZH2 can have both oncogenic and tumor suppressive functions by increasing or decreasing H3K27me3. (Review)

  6. Loss of EZH2 expression is associated with increased transformation of myelodysplastic syndrome into acute myeloid leukemia (show BCL11A Antibodies).

  7. miR (show MLXIP Antibodies)-214 was able to prevent cell death by targeting EZH2, the catalytic core component of PRC2 complex that is responsible for tri (show VANGL2 Antibodies)-methylation reaction at lysine 27 (K27 (show KRT27 Antibodies)) of histone 3 (H3 (show HIST3H3 Antibodies)) (H3K27me3), by which As-induced miR (show MLXIP Antibodies)-214 reduction

  8. In patients with B-cell non-hodgkin's lymphoma, none of them had well-known hot spot mutations in EZH2 and CD79B (show CD79B Antibodies).

  9. EZH2 overexpression was associated with poor overall survival in lung cancer, this effect appears also significant when the analysis is restricted in Asian population, lung AC and stage I patients, but not among Caucasians.

  10. expression of EZH2 and H3K27me3 could serve as biomarkers in the prediction of esophageal squamous cell carcinoma (ESCC) patients' survival and ESCC metastasis.

Mouse (Murine) Enhancer of Zeste Homolog 2 (Drosophila) (EZH2) interaction partners

  1. Genetic inactivation of Ezh2 or Eed (show EED Antibodies) cooperates with NRASQ61K in leukemogenesis.

  2. Study demonstrated that redundant EZH2 shifted mesenchymal stem cell lineage commitment to adipocyte, which contributed to the development of osteoporosis.

  3. Data indicate increased natural killer (NK) lineage cells in Ezh2 (enhancer of zeste homolog 2)-deficient mice.

  4. Ezh2 cooperates with let-7 microRNAs in silencing the fetal gene signature in BM HSPCs and restricts their transformation.

  5. Conditional deletion of Ezh2 in the developing midbrain resulted in decreased neural progenitor proliferation, which is associated with derepression of cell cycle inhibitors and negative regulation of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  6. The dichotomous function of EZH2 in regulating differentiation and senescence in effector and regulatory T cells helps to explain the apparent existing contradictions in literature.

  7. Modulation of Polycomb repressive complexes by either Ezh2 overexpression or Eed deletion enhances KRAS-driven adenomagenesis and inflammation

  8. Study used Ezh2 conditional knockout mice to clarify the role of histone H3K27me3 modification in the retina

  9. The presence of EZH2 is required to control progressive differentiation of milk secreting epithelium during pregnancy.

  10. These results clearly demonstrated an essential role of Ezh1 (show EZH1 Antibodies) in the pathogenesis of hematopoietic malignancies induced by Ezh2 insufficiency, and highlighted the differential functions of Ezh1 (show EZH1 Antibodies) and Ezh2 in hematopoiesis.

EZH2 Antigen Profile

Antigen Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with EZH2

  • enhancer of zeste homolog 2 (Drosophila) (EZH2) antibody
  • enhancer of zeste homolog 2 (ezh2) antibody
  • enhancer of zeste homolog 2 (ezh2-a) antibody
  • enhancer of zeste homolog 2 (Drosophila) (Ezh2) antibody
  • enhancer of zeste homolog 2 (Drosophila) (ezh2) antibody
  • Enx-1 antibody
  • ENX1 antibody
  • Enx1h antibody
  • eya2 antibody
  • EZH1 antibody
  • ezh2 antibody
  • EZH2b antibody
  • im:7149338 antibody
  • KMT6 antibody
  • KMT6A antibody
  • mKIAA4065 antibody
  • olezh2 antibody
  • WVS antibody
  • WVS2 antibody
  • xez antibody
  • zgc:136376 antibody
  • zgc:152758 antibody

Protein level used designations for EZH2

enhancer of zeste 2 , enhancer of zeste homolog 2 (Drosophila) , Polycomb protein EZH2 , histone-lysine N-methyltransferase EZH2 , histone-lysine N-methyltransferase EZH2-like , Enhancer of zeste homolog 2-A , Polycomb protein EZH2-A , lysine N-methyltransferase 6 , enhancer of zeste homolog 2 , eyes absent homolog 2

GENE ID SPECIES
745437 Pan troglodytes
100051290 Equus caballus
550047 Xenopus (Silurana) tropicalis
709075 Macaca mulatta
100125823 Oryzias latipes
100394758 Callithrix jacchus
100447447 Pongo abelii
100540374 Meleagris gallopavo
100580962 Nomascus leucogenys
399174 Xenopus laevis
2146 Homo sapiens
14056 Mus musculus
420784 Gallus gallus
475511 Canis lupus familiaris
100625497 Sus scrofa
509106 Bos taurus
312299 Rattus norvegicus
768133 Danio rerio
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