You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-ALK (ALK) Antibodies

Full name:
anti-Anaplastic Lymphoma Receptor tyrosine Kinase Antibodies (ALK)
On www.antibodies-online.com are 0 Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) Antibodies from different suppliers available. A total of 0 ALK products are currently listed.
Synonyms:
ALK, CD246, NBLST3, Tcrz
list all antibodies Gene Name GeneID UniProt
Anti-Mouse ALK ALK 11682 P97793
Anti-Human ALK ALK 238 Q9UM73
Anti-Rat ALK ALK 266802  

Show all synonyms

More Antibodies against ALK Interaction Partners

Mouse (Murine) Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) interaction partners

  1. An oral anaplastic lymphoma kinase (ALK) inhibitor.

  2. ALK knock out male mice exhibit hypogonadotropic hypogonadism.

  3. Ethanol activates ALK (and MDK (show MDK Antibodies)) signaling in the brain which regulates behaviors related to alcohol abuse.

  4. Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice.

  5. Mutations in the ALK gene is associated with neuroblastoma (show ARHGEF16 Antibodies).

  6. Th-MYCN (show MYCN Antibodies) genetically-engineered murine models of neuroblastoma (show ARHGEF16 Antibodies) using MRI (show C7ORF49 Antibodies), we have identified a marked ALK(F1174L)-driven vascular phenotype.

  7. Reduced ALK1 (show ACVRL1 Antibodies) expression is associated with increased extracellular matrix protein expression, proliferation and migration in fibroblasts.

  8. findings demonstrate a pathogenic role for ALK(F1174L) in neuroblastomas overexpressing MYCN (show MYCN Antibodies) and suggest a strategy for improving targeted therapy for ALK-positive neuroblastoma (show ARHGEF16 Antibodies)

  9. KLC1 (show KLC1 Antibodies)-ALK is the first novel oncogenic fusion identified using only formalin-fixed paraffin-embedded tissue tissues

  10. In hippocampus, Alk and Ltk (leukocyte tyrosine kinase (show LTK Antibodies)) are expressed throughout dentate gyrus, CA1 (show CA1 Antibodies), and CA3 (show CA3 Antibodies). Data suggest enhanced performance in spatial memory and reduced neurogenesis in Alk mutant/knockout mice.

Human Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) interaction partners

  1. TERT (show TERT Antibodies) promoter mutation is an independent predictor for distant metastasis of thyroid neoplasms, but ALK testing is not useful for clinical decision-making in Korean patients with a high prevalence of the BRAF (show BRAF Antibodies) V600E mutation.

  2. Data show that anaplastic lymphoma kinase (ALKinhibitor ASP3026 was well tolerated with no treatment-related deaths.

  3. Cystic Brain Metastases Occurring in Anaplastic Lymphoma Kinase Gene Rearranged Non-Small-Cell Lung Cancer Patients Receiving Crizotinib.

  4. We will also provide a timely review on all ALK inhibitors and their current status of development in clinical settings

  5. Non-CpG methylation observed essentially in clinically favorable cases was associated with the differentiation status of neuroblastoma (show ARHGEF16 Antibodies) and expression of key genes such as ALK.

  6. Data show that inhibition of echinoderm microtubule-associated protein-like 4 (EML4 (show EML4 Antibodies))-anaplastic lymphoma kinase (ALK)-mediated stem-like properties enhances the anti-tumor effect.

  7. Data identified several cases of complex EGFR (show EGFR Antibodies) mutations, and concomitant EGFR (show EGFR Antibodies) mutations and ALK rearrangements in non-small cell lung cancer

  8. ALK and ROS1 rearrangements found in advanced non-small cell lung cancer patients

  9. Meta-analysis: immunohistochemistry assay using D5F3 and 5A4 antibodies reliably detected NSCLC with ALK rearrangement and may be useful as a screening method to identify these tumors.

  10. In conclusion, these data show that ALK is robustly activated by the FAM150A/B ligands.

ALK Antigen Profile

Antigen Summary

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)\\/EML4 (chromosome 2), ALK\\/RANBP2 (chromosome 2), ALK\\/ATIC (chromosome 2), ALK\\/TFG (chromosome 3), ALK\\/NPM1 (chromosome 5), ALK\\/SQSTM1 (chromosome 5), ALK\\/KIF5B (chromosome 10), ALK\\/CLTC (chromosome 17), ALK\\/TPM4 (chromosome 19), and ALK\\/MSN (chromosome X).

Alternative names and synonyms associated with ALK

  • anaplastic lymphoma kinase (Alk) antibody
  • anaplastic lymphoma receptor tyrosine kinase (ALK) antibody
  • ALK tyrosine kinase receptor-like (LOC536642) antibody
  • anaplastic lymphoma receptor tyrosine kinase (Alk) antibody
  • ALK antibody
  • CD246 antibody
  • NBLST3 antibody
  • Tcrz antibody

Protein level used designations for ALK

ALK tyrosine kinase receptor , anaplastic lymphoma kinase (Ki-1) , CD246 antigen , mutant anaplastic lymphoma kinase , anaplastic lymphoma receptor tyrosine kinase , anaplastic lymphoma kinase

GENE ID SPECIES
11682 Mus musculus
421297 Gallus gallus
238 Homo sapiens
483021 Canis lupus familiaris
100518423 Sus scrofa
536642 Bos taurus
266802 Rattus norvegicus
Did you look for something else?