You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-ALK (ALK) Antibodies

Full name:
anti-Anaplastic Lymphoma Receptor tyrosine Kinase Antibodies (ALK)
On www.antibodies-online.com are 0 Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) Antibodies from different suppliers available. A total of 0 ALK products are currently listed.
Synonyms:
ALK, CD246, NBLST3, Tcrz
list all antibodies Gene Name GeneID UniProt
Anti-Mouse ALK ALK 11682 P97793
Anti-Human ALK ALK 238 Q9UM73
Anti-Rat ALK ALK 266802  

Show all synonyms

More Antibodies against ALK Interaction Partners

Mouse (Murine) Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) interaction partners

  1. ALK knock out male mice exhibit hypogonadotropic hypogonadism.

  2. Ethanol activates ALK (and MDK (show MDK Antibodies)) signaling in the brain which regulates behaviors related to alcohol abuse.

  3. Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice.

  4. Mutations in the ALK gene is associated with neuroblastoma (show ARHGEF16 Antibodies).

  5. Th-MYCN (show MYCN Antibodies) genetically-engineered murine models of neuroblastoma (show ARHGEF16 Antibodies) using MRI (show C7ORF49 Antibodies), we have identified a marked ALK(F1174L)-driven vascular phenotype.

  6. Reduced ALK1 (show ACVRL1 Antibodies) expression is associated with increased extracellular matrix protein expression, proliferation and migration in fibroblasts.

  7. findings demonstrate a pathogenic role for ALK(F1174L) in neuroblastomas overexpressing MYCN (show MYCN Antibodies) and suggest a strategy for improving targeted therapy for ALK-positive neuroblastoma (show ARHGEF16 Antibodies)

  8. KLC1 (show KLC1 Antibodies)-ALK is the first novel oncogenic fusion identified using only formalin-fixed paraffin-embedded tissue tissues

  9. In hippocampus, Alk and Ltk (leukocyte tyrosine kinase (show LTK Antibodies)) are expressed throughout dentate gyrus, CA1 (show CA1 Antibodies), and CA3 (show CA3 Antibodies). Data suggest enhanced performance in spatial memory and reduced neurogenesis in Alk mutant/knockout mice.

  10. High anaplastic lymphoma kinase is associated with angiogenesis in neuroblastoma (show ARHGEF16 Antibodies).

Human Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) interaction partners

  1. In conclusion, these data show that ALK is robustly activated by the FAM150A/B ligands.

  2. These findings are of clinical importance given the potential role of ALK mutations in clonal evolution and relapse.

  3. Data show FAM150B, which was named as augmentor-alpha (AUG-alpha), binds and activtes both anaplastic lymphoma kinase (ALK) and tyrosine kinase (show TXK Antibodies) (LTK (show LTK Antibodies)).

  4. Suggest novel small molecule ALK inhibitors combined with RNA interfering based nanoliposomes in treatment of neuroblastomas.

  5. analysis of ALK rearrangement in colorectal adenocarcinoma by immunohistochemistry screening

  6. Results suggest that co-treatment with crizotinib and chloroquine could be beneficial for ALK-positive ALK-positive anaplastic large cell lymphoma patients.

  7. the discovery of EGFR (show EGFR Antibodies) mutations and ALK rearrangements has enabled the identification of patients who are more likely to benefit from a specific drug.

  8. Rather than by secondary ALK mutations.

  9. Data show that 11/105 patients failed all molecular analysis: no mutations in oncogenes EGFR (show EGFR Antibodies), KRAS and NRAS (show NRAS Antibodies) were detected, and no ALK gene rearrangements or MET gene amplifications were identified.

  10. This review describes the biology of EML4 (show EML4 Antibodies) and ALK, explains the main features of EML4 (show EML4 Antibodies)-ALK fusion proteins and outline the therapies that target EML4 (show EML4 Antibodies)-ALK in cancer. [review]

ALK Antigen Profile

Antigen Summary

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)\\/EML4 (chromosome 2), ALK\\/RANBP2 (chromosome 2), ALK\\/ATIC (chromosome 2), ALK\\/TFG (chromosome 3), ALK\\/NPM1 (chromosome 5), ALK\\/SQSTM1 (chromosome 5), ALK\\/KIF5B (chromosome 10), ALK\\/CLTC (chromosome 17), ALK\\/TPM4 (chromosome 19), and ALK\\/MSN (chromosome X).

Alternative names and synonyms associated with ALK

  • anaplastic lymphoma kinase (Alk) antibody
  • anaplastic lymphoma receptor tyrosine kinase (ALK) antibody
  • ALK tyrosine kinase receptor-like (LOC536642) antibody
  • anaplastic lymphoma receptor tyrosine kinase (Alk) antibody
  • ALK antibody
  • CD246 antibody
  • NBLST3 antibody
  • Tcrz antibody

Protein level used designations for ALK

ALK tyrosine kinase receptor , anaplastic lymphoma kinase (Ki-1) , CD246 antigen , mutant anaplastic lymphoma kinase , anaplastic lymphoma receptor tyrosine kinase , anaplastic lymphoma kinase

GENE ID SPECIES
11682 Mus musculus
421297 Gallus gallus
238 Homo sapiens
483021 Canis lupus familiaris
100518423 Sus scrofa
536642 Bos taurus
266802 Rattus norvegicus
Did you look for something else?