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Browse our AXL Proteins (AXL)

Full name:
AXL Receptor tyrosine Kinase Proteins (AXL)
On are 18 AXL Receptor tyrosine Kinase (AXL) Proteins from 10 different suppliers available. Additionally we are shipping AXL Antibodies (264) and AXL Kits (28) and many more products for this protein. A total of 327 AXL products are currently listed.
AI323647, Ark, JTK11, Tyro7, Ufo
list all proteins Gene Name GeneID UniProt
AXL 558 P30530
AXL 26362 Q00993
AXL 308444  

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AXL Proteins (AXL) by Origin

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Top referenced AXL Proteins

  1. Human AXL Protein expressed in HEK-293 Cells - ABIN2180607 : Varnum, Young, Elliott, Garcia, Bartley, Fridell, Hunt, Trail, Clogston, Toso: Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6. in Nature 1995 (PubMed)
    Show all 4 references for ABIN2180607

  2. Mouse (Murine) AXL Protein expressed in Human Cells - ABIN2007367 : Nagata, Ohashi, Nakano, Arita, Zong, Hanafusa, Mizuno: Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. in The Journal of biological chemistry 1997 (PubMed)
    Show all 3 references for ABIN2007367

  3. Human AXL Protein expressed in Human Cells - ABIN2002499 : Braunger, Schleithoff, Schulz, Kessler, Lammers, Ullrich, Bartram, Janssen: Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site. in Oncogene 1997 (PubMed)
    Show all 3 references for ABIN2002499

More Proteins for AXL Interaction Partners

Human AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. Axl expression suggests more aggressive tumor invasiveness and predicts worse prognosis for HCC (show FAM126A Proteins) patients undergoing resection.

  2. Most importantly, in an intracranial tumour model with BP wafer in situ treatment, we demonstrated that the BP wafer not only significantly increased the survival rate but also decreased Axl expression, and inhibited tumour invasion

  3. these results suggested that Axl, which is regulated by long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1, may exert great influence on invasion and migration of neuroblastoma (show ARHGEF16 Proteins)

  4. AXL overexpression or activation through growth arrest-specific 6 (Gas6 (show GAS6 Proteins)) ligand stimulation increases MDMX (show MDM4 Proteins) and MDM2 (show MDM2 Proteins) protein levels and decreases p53 (show TP53 Proteins) activity.

  5. Structure, regulation, and function of AXL; the role of AXL in the tumor microenvironment; the development of AXL as a therapeutic target; and areas of ongoing and future investigation.[review]

  6. Study provides evidence that AXL and MET are associated with cell proliferation and metastasis in lung cancer, and the crosstalk between these receptors affects tumor progression.

  7. these results confirm the correlation between AXL and PKCalpha (show PKCa Proteins), and suggest PKCalpha (show PKCa Proteins)-AXL signaling may be a treatment target, particularly in malignant cancer cells.

  8. Authors concluded that the molecular mechanisms of AXL mediated resistance involved in the increased activity of the PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) and MAPK (show MAPK1 Proteins)/ERK1/2 pathways, and AXL overexpression could promote resistance, but it can be weakened when AXL expression is silenced.

  9. The study suggests that Axl may play a role in the function of endothelial progenitor cells, thereby being involved in the pathogenesis of preeclampsia.

  10. Data show that strong AXL expression in surgically resected that lung adenocarcinomas (LADs) was a predictor of poor prognosis.

Mouse (Murine) AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.

  2. Axl, Mertk (show MERTK Proteins) and Tyro3 (show TYRO3 Proteins) receptors are not required for Zika virus entry and infection.

  3. Axl plays an essential role in the regulation of NK cell development as well as natural killer effector function.

  4. Matrix metalloproteases ADAM10 (show ADAM10 Proteins) and TACE (ADAM17 (show ADAM17 Proteins)) cleave AXL receptor tyrosine kinase (Axl) in lupus-prone leukocytes.

  5. Gas6 (show GAS6 Proteins)/Axl and Akt (show AKT1 Proteins)/FoxO1a (show FOXO1 Proteins) were involved in protective effects of testosterone on VSMCs senescence and collagen synthesis.

  6. Axl allows specific identification of airway macrophages, and that its expression is critical for macrophage functional compartmentalization in the airspaces or lung interstitium.

  7. results establish TAM (show CCNA1 Proteins) receptors as both controllers of microglial physiology and potential targets for therapeutic intervention in central nervous system disease

  8. These results suggest that TAM (show CCNA1 Proteins) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.

  9. Gas6 (show GAS6 Proteins)-induced Axl signaling is a critical driver of pancreatic cancer progression.

  10. The results indicate that Axl and Mer (show ERH Proteins) receptors cooperatively regulate the systemic immune tolerance to male germ cell antigens.

Cow (Bovine) AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. activation of receptor tyrosine kinase (show RET Proteins) Axl inhibits the osteogenic differentiation of vascular pericytes.

AXL Protein Profile

Protein Summary

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with AXL

  • AXL receptor tyrosine kinase (AXL)
  • AXL receptor tyrosine kinase (Axl)
  • Axl receptor tyrosine kinase (Axl)
  • AI323647 protein
  • Ark protein
  • JTK11 protein
  • Tyro7 protein
  • Ufo protein

Protein level used designations for AXL

AXL oncogene , AXL transforming sequence/gene , tyrosine-protein kinase receptor UFO , adhesion-related kinase , ufo oncogene homolog

100064907 Equus caballus
558 Homo sapiens
26362 Mus musculus
308444 Rattus norvegicus
484490 Canis lupus familiaris
100144875 Sus scrofa
516598 Bos taurus
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